scholarly journals An Experimental Pilot Study of Global Postural Reeducation Concerning the Cognitive Approach of Patients With Alzheimer’s Disease

2019 ◽  
Vol 35 ◽  
pp. 153331751986782 ◽  
Author(s):  
Jasemin Todri ◽  
Orges Lena ◽  
José Luis Martínez Gil

Background: Several recent studies have examined the positive effects of physical exercise and equilibrium on individuals with neurodegenerative diseases. Objectives: In this sense, this study based on an experimental design, tested whether global postural reeducation (GPR) can affect equilibrium and cognition, life quality, and psychological symptoms of patients with Alzheimer’s disease (AD). Methods: One hundred thirty-five participants with mild and moderate AD diagnosis were assigned to 2 groups: experimental group (EG, n = 90) and control group (CG, n = 45). The GPR therapy was implemented in the EG for 6 months, while both groups underwent neuropsychological assessments prior and after the 6-month period. Results: According to the repeated measures of analysis of variance, significant differences between groups were found at the 6-month follow-up period, in benefit of the EG such as Mini-Mental State Examination ( P = .000), Geriatric Depression Scale ( P = .000), Neuropsychiatric Inventory ( P = .000), quality of life in AD/patient ( P = .000), quality of life in AD/caregivers ( P = .000), Barthel index ( P = .000), and Tinetti Scale ( P = .000), while the CG showed a low performance in the neuropsychological tests. Conclusions: We suggest that GPR is a therapeutic option, which can improve the psychological, physical, and cognitive aspects of patients with AD.

2009 ◽  
Vol 3 (3) ◽  
pp. 241-247 ◽  
Author(s):  
Fernanda Machado ◽  
Paula V. Nunes ◽  
Luciane F. Viola ◽  
Franklin S. Santos ◽  
Orestes V. Forlenza ◽  
...  

Abstract Quality of life is seldom explored in evaluations of therapeutic interventions in Alzheimer's disease. Objective: To verify whether participation in a cognitive and functional rehabilitation program improves quality of life (QOL) among Alzheimer's disease (AD) patients. Methods: 19 AD patients participated in this study, 12 of whom attended 24 multi-professional intervention sessions - the experimental group - whereas the remaining 7 comprised the control group. The following tools were used to assess changes: a) Mini-Mental State Examination (MMSE); b) Geriatric Depression Scale (GDS); c) Quality of Life in AD evaluation scale (QOL-AD); d) Open question on QOL. Results: Participation had no positive impact on quantitative clinical variables (MMSE, GDS, QOL-AD). The answers to the open question, examined using the Collective Subject Discourse (CSD) method, suggested that QOL improved after the intervention. Conclusion: Combining pharmacological treatment with psychosocial intervention may prove to be an effective strategy to enhance the QOL of AD patients.


2019 ◽  
Vol 18 (4) ◽  
pp. 27-37
Author(s):  
Angie L. Sardina, PhD ◽  
Suzanne Fitzsimmons, MSN, ARNP, GNP ◽  
Catherine M. Hoyt, BA ◽  
Linda L. Buettner, PhD

This study evaluated whether a mentally stimulating activities (MSA) program reduced neuropsychiatric symptoms and improved cognitive status and quality of life, as compared to a support group for persons in the early stage of Alzheimer’s disease (AD). This randomized controlled trial included 81 adults (aged 55+), who were randomly assigned to the MSA group (treatment) or a social support group (control). A repeated measures multivariate analysis of variance (MANOVA) identified that MSA participants significantly reduced apathy (p 0.001) and depressive symptoms (p 0.001), as well as improved cognitive status (p 0.001) and quality of life (p 0.001) as compared to the control group. A structured classroom-style MSA program may be a viable and therapeutic intervention to alleviate neuropsychiatric symptoms, and improve cognitive status and quality of life in early-stage AD.


2016 ◽  
Vol 28 (8) ◽  
pp. 1399-1400 ◽  
Author(s):  
Martin Nikolaus Dichter ◽  
Eva-Maria Wolschon ◽  
Gabriele Meyer ◽  
Sascha Köpke

Dementia is a chronic and currently incurable syndrome. Therefore, quality of life (QoL) is a major goal when caring for people with dementia (Gibson et al., 2010) and a major outcome in dementia research (Moniz-Cook et al., 2008). The measurement of QoL, especially proxy-rating, is challenging because of the proxy-perspective (Pickard and Knight, 2005), reliability (Dichter et al., 2016), validity (O'Rourke et al., 2015), and responsiveness (Perales et al., 2013). Probably due to these challenges, it has not been possible to show positive effects for QoL in almost all non-pharmacological interventions for people with dementia (Cooper et al., 2012). One recommended (Moniz-Cook et al., 2008) and frequently used instrument is the Quality of Life in Alzheimer's Disease scale (QoL-AD), which was originally developed in the US for community-dwelling people with dementia. The QoL-AD consists of 13 items based on a 4-point Likert scale ranging from “1”=poor to “4”=excellent (Logsdon et al., 1999). The original instrument has been adapted for people living in nursing homes (NH) by Edelmann et al. (2005).


2003 ◽  
Vol 183 (3) ◽  
pp. 248-254 ◽  
Author(s):  
Aimee Spector ◽  
Lene Thorgrimsen ◽  
Bob Woods ◽  
Lindsay Royan ◽  
Steve Davies ◽  
...  

BackgroundA recent Cochrane review of reality orientation therapy identified the need for large, well-designed, multi-centre trials.AimsTo test the hypothesis that cognitive stimulation therapy (CST) for older people with dementia would benefit cognition and quality of life.MethodA single-blind, multi-centre, randomised controlled trial recruited 201 older people with dementia. The main outcome measures were change in cognitive function and quality of life. An intention-to-treat analysis used analysis of covariance to control for potential variability in baseline measures.ResultsOne hundred and fifteen people were randomised within centres to the intervention group and 86 to the control group. At follow-up the intervention group had significantly improved relative to the control group on the Mini-Mental State Examination (P=0.044), the Alzheimer's Disease Assessment Scale – Cognition (ADAS–Cog) (P=0.014) and Quality of Life – Alzheimer's Disease scales (P=0.028). Using criteria of 4 points or more improvement on the ADAS–Cog the number needed to treat was 6 for the intervention group.ConclusionThe results compare favourably with trials of drugs for dementia. CST groups may have worthwhile benefits for many people with dementia.


2013 ◽  
Vol 25 (8) ◽  
pp. 1345-1355 ◽  
Author(s):  
Livia Pfeifer ◽  
Reinhard Drobetz ◽  
Sonja Fankhauser ◽  
Moyra E. Mortby ◽  
Andreas Maercker ◽  
...  

ABSTRACTBackground: Caregivers of individuals with dementia are biased in their rating of mental health measures of the care receiver. This study examines caregiver burden and depression as predictors of this bias for mild cognitive impairment and mild Alzheimer's disease in different domains.Methods: The sample consisted of 202 persons: 60 with mild cognitive impairment, 41 with mild Alzheimer's disease, and 101 caregivers. Discrepancy scores were calculated by subtracting the mean caregiver score from the respective mean patient score on the following assessment instruments: the Geriatric Depression Scale, Apathy Evaluation Scale, Bayer-Activities of Daily Living Scale, and Quality of Life-AD scale. Caregiver burden and depression were assessed by the Zarit Burden Interview and the Center for Epidemiologic Studies Depression Scale.Results: Intraclass correlation coefficients were low for apathy (0.38), daily functioning (0.38), and quality of life (0.30) and moderate for depression (0.49). These domains showed negative rating discrepancies, which indicates caregiver rating bias for all four domains. Regression analyses revealed that caregiver burden significantly contributed to explaining these discrepancies in the domains apathy, daily functioning, and quality of life.Conclusion: Caregiver rating bias can be attributed to caregiver burden. When caregiver burden is present, data based on caregiver ratings should therefore be interpreted with caution.


Author(s):  
R. Rokkaku ◽  
A. Homma ◽  
S. Kobayashi ◽  
Y. Seki

An aim of the present study is to examine the impact of inter-generational cooperation on the quality of life of elderly Alzheimer’s sufferers. The study is a continuing, two-year intervention report. The subject consist of an intervention and a control groups of six and five sufferers, respectively, who were diagnosed with Alzheimer’s disease. Both groups attend day care services. The intervention group participates in the inter-generational program with children, while the control group does not. In the results, the score of Quality of Life – Alzheimer’s disease (QOL-AD ) of the subjects has been significantly higher in the intervention group comparing with that of the control group. been significantly higher in the intervention group comparing with that of the control group. Also the Philadelphia Geriatric Center Affect Rating Scale(PGC-ARS), have been significantly higher in the intervention group those in the control group., The magnitude of the change was not so remarkable as to influence QOL-AD at home. The present intergenerational cooperation may improve the quality of life of moderate to severe Alzheimer’s sufferers.


2018 ◽  
Vol 46 (1-2) ◽  
pp. 109-118 ◽  
Author(s):  
Helena Kisvetrová ◽  
David Školoudík ◽  
Roman Herzig ◽  
Martin Vališ ◽  
Božena Jurašková ◽  
...  

Background/Aims: The aim of this study was to perform a psychometric validation of the Czech version of the Quality of Life – Alzheimer’s Disease scale (QoL-AD) for patients with early-stage dementia. Methods: The sample included 212 patient-proxy pairs. For convergent validity, the Czech version of the Bristol Activities of Daily Living Scale (BADLS-CZ), the Short Physical Performance Battery (SPPB), and the Geriatric Depression Scale (GDS) were used. Results: The reliability of the QoL-AD for patients and caregivers was good (Cronbach’s α = 0.85, ICC = 0.25–0.54). A positive correlation existed between the QoL-AD and the SPPB, and negative correlations existed between the QoL-AD and the BADLS-CZ as well as between the QoL-AD and the GDS. Factor analysis resulted in a three-factor solution (physical and mental health, family life, and social security). Conclusion: The Czech version of the QoL-AD has good psychometric properties in compliance with international recommendations.


2021 ◽  
Author(s):  
Xin Yu

Abstract BackgroundMusic intervention has been found to be beneficial for neurological diseases, especially in slowing down the progression of clinical symptom in patients. However, it remains unclear to what extend can music intervention may affect patients with Alzheimer’s disease (AD). Questions remain on whether music intervention can improve the quality of life (QOL) of AD patients, who are usually with poor QOL owning to the burden of disease.MethodsA search that compared the effectiveness of music intervention to improve the QOL of AD patients were carried out. PubMed, Cochrane library clinical trial database, and WANFANG database were searched to collect data from randomized controlled trials (RCTs). Two independent researchers extracted data from the selected eligible articles by using collection form and RevMan5.3 statistical software and applied for the meta-analysis.ResultsWe included six RCTs in our meta-analysis. The results showed that compared to the control group, music intervention can significantly increase the score of the QOL-AD scale (MD=5.10, 95%CI: 2.95-7.24, P<0.001) and The World Health Organization QOL Rating Scale Short Form score (MD=5.76, 95%CI: 1.59-9.92, P=0.007). ConclusionsResults suggested that music intervention could improve the QOL for the elderly patients with AD. Our findings indicated that music intervention might be considered as a non-pharmaceutical therapy for patients with AD in the future.


2010 ◽  
Vol 51 (02) ◽  
pp. 72 ◽  
Author(s):  
Oscar Rosas Carrasco ◽  
Laura del Pilar Torres Arreola ◽  
María de Guadalupe Guerra Silla ◽  
Sara Torres Castro ◽  
Luis Miguel Gutiérrez Robledo

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