Cumulative Socioeconomic Adversity, Developmental Pathways, and Mental Health Risks During the Early Life Course

2016 ◽  
Vol 4 (6) ◽  
pp. 378-390 ◽  
Author(s):  
Kandauda A. S. Wickrama ◽  
Catherine Walker O’Neal ◽  
Tae Kyoung Lee
BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e039583
Author(s):  
Lauren E Carson ◽  
Borscha Azmi ◽  
Amelia Jewell ◽  
Clare L Taylor ◽  
Angela Flynn ◽  
...  

PurposeLinked maternity, neonatal and maternal mental health records were created to support research into the early life origins of physical and mental health, in mothers and children. The Early Life Cross Linkage in Research (eLIXIR) Partnership was developed in 2018, generating a repository of real-time, pseudonymised, structured data derived from the electronic health record systems of two acute and one Mental Health Care National Health Service (NHS) Provider in South London. We present early descriptive data for the linkage database and the robust data security and governance structures, and describe the intended expansion of the database from its original development. Additionally, we report details of the accompanying eLIXIR Research Tissue Bank of maternal and neonatal blood samples.ParticipantsDescriptive data were generated from the eLIXIR database from 1 October 2018 to 30 June 2019. Over 17 000 electronic patient records were included.Findings to date10 207 women accessed antenatal care from the 2 NHS maternity services, with 8405 deliveries (8772 infants). This diverse, inner-city maternity service population was born in over 170 countries with an ethnic profile of 46.1% white, 19.1% black, 7.0% Asian, 4.1% mixed and 4.1% other. Of the 10 207 women, 11.6% had a clinical record in mental health services with 3.0% being treated during their pregnancy. This first data extract included 947 infants treated in the neonatal intensive care unit, of whom 19.1% were postnatal transfers from external healthcare providers.Future plansElectronic health records provide potentially transformative information for life course research, integrating physical and mental health disorders and outcomes in routine clinical care. The eLIXIR database will grow by ~14 000 new maternity cases annually, in addition to providing child follow-up data. Additional datasets will supplement the current linkage from other local and national resources, including primary care and hospital inpatient data for mothers and their children.


2013 ◽  
Author(s):  
Jukka Vuori ◽  
Salla Toppinen-Tanner ◽  
Amiram D. Vinokur ◽  
Inbal Nahum-Shani ◽  
Richard H. Price

Author(s):  
Lene Arnett Jensen

This chapter introduces The Oxford Handbook of Moral Development: An Interdisciplinary Perspective. The handbook provides a comprehensive, international, and up-to-date review of research on moral development, including moral motives and behaviors, ontogeny and developmental pathways, and contexts that children, adolescents, and adults experience with respect to morality. Across more than 40 chapters, experts from disciplines such as anthropology, education, human development, psychology, and sociology address moral development through the entire life course among diverse groups within and across countries. This chapter addresses how the chapters provide literature reviews that are inclusive of highly diverse theoretical and research foci, as well as of diverse cultural, socioeconomic, and gender groups. The aim of the handbook is to contribute to the revitalization and flourishing of the field of moral development.


2020 ◽  
Vol 49 (1) ◽  
pp. 55-62
Author(s):  
Anne Nordrehaug Åstrøm ◽  
Otto Robert Frans Smith ◽  
Gerhard Sulo
Keyword(s):  

2021 ◽  
pp. 002214652110054
Author(s):  
Sarah A. Mustillo ◽  
Miao Li ◽  
Patricia Morton ◽  
Kenneth F. Ferraro

Prior research reveals that negative early-life experiences play a major role in the development of obesity in later life, but few studies identify mechanisms that alter the lifetime risk of obesity. This study examines the influence of negative childhood experiences on body mass index (BMI) and obesity (BMI ≥30) during older adulthood and the psychosocial and behavioral pathways involved. Using a nationally representative sample, we examine the influence of cumulative misfortune as well as five separate domains of misfortune on BMI and obesity. Results show that four of the five domains are associated with BMI and obesity either directly, indirectly, or both. The influence of cumulative misfortune on the outcomes is mediated by three adult factors: socioeconomic status, depressive symptoms, and physical activity. The mediators identified here provide targets for intervention among older adults to help offset the health risks of excess BMI attributable of early-life exposure to misfortune.


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