The association of body mass index with endometriosis and disease severity in women with pain

2018 ◽  
Vol 10 (2) ◽  
pp. 79-87 ◽  
Author(s):  
Sarah J Holdsworth-Carson ◽  
Uri P Dior ◽  
Eliza M Colgrave ◽  
Martin Healey ◽  
Grant W Montgomery ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Retrospective Study ◽  
Disease Severity ◽  
Body Mass ◽  
Inverse Relationship ◽  
Population Based ◽  
The Body ◽  
World Health ◽  
Obese Women ◽  
American Fertility Society

Introduction: There is a well-established inverse relationship between body mass index and frequency of endometriosis. However, these population-based studies have relied mostly on self-reported cases of endometriosis, rather than surgically confirmed endometriosis where disease severity has been objectively assessed. The aim of the current retrospective study was to establish whether the established relationship between endometriosis and low body mass index was independent of disease severity. Methods: Women with menstrual and/or pelvic pain undergoing laparoscopy for suspected endometriosis were recruited for this retrospective study (n = 509). Women were grouped by body mass index (kg/m2) according to World Health Organization criteria: underweight (<18.5), normal (18.5–24.99), pre-obese (25–29.99) or obese (≥30). Endometriosis was scored according to the revised American Fertility Society system. Data were analysed based on body mass index and endometriosis status to identify any relationship between body mass index and disease. Results: The average body mass index of women with endometriosis was 25.0 kg/m2. The body mass index distribution of women with endometriosis differed relative to women in the general population. As expected, fewer obese women had endometriosis than in the lower body mass index categories. However, the obese women who did have endometriosis had significantly higher revised American Fertility Society scores compared to women with normal and pre-obese body mass indices. Discussion: Our results are consistent with the established finding of an inverse relationship between body mass index and endometriosis. The novel finding from this study is that obesity is associated with increased disease severity and reduced frequency of stage I endometriosis. It remains unclear what role body mass index has in the cause or effect of endometriosis; we speculate that body mass index may be useful for sub-classifying the disease.

Anaesthetic Management of a Super Morbid Obese Patient

2021 ◽  
Vol 8 (32) ◽  
pp. 3039-3042
Author(s):  
Lekshmi Raj Jalaja ◽  
Stuti Lohia ◽  
Priyadarsini Bentur ◽  
Ravi Ramgiri
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Recovery Period ◽  
Well Being ◽  
Anaesthetic Management ◽  
The Body ◽  
World Health ◽  
Morbidly Obese ◽  
Multisystem Disorder ◽  
Increased Risk

‘Obesity’ is defined as a condition with excess body fat to the extent that health and well-being are adversely affected and uses a class system based on the body mass index (BMI), by the world health organization (WHO). Anaesthetic management of morbidly obese is challenging, as there is an increased risk of perioperative respiratory insufficiency and supplemental oxygen must be given throughout recovery period. The incidence of morbid obesity continues to grow and anaesthesiologists are exposed to obese patients presenting for various procedures. The prevalence of obesity is on the upward trend worldwide. Obesity is a multisystem disorder, involving the respiratory and cardiovascular systems, and therefore, undergoing a surgical procedure under anaesthesia may entail a considerable risk. Thus, a multidisciplinary approach is required in treating such patients. Quantification of the extent of obesity is done using the body mass index. BMI is defined as the relationship between weight and height (weight [kg] / height2 [m2 ]).

The association of body mass index, weight gain and central obesity with activity-related breathlessness: the Swedish Cardiopulmonary Bioimage Study

Thorax ◽  
2019 ◽  
Vol 74 (10) ◽  
pp. 958-964 ◽  
Author(s):  
Magnus Pär Ekström ◽  
Anders Blomberg ◽  
Göran Bergström ◽  
John Brandberg ◽  
Kenneth Caidahl ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Weight Gain ◽  
Body Mass ◽  
Lung Volume ◽  
Airflow Obstruction ◽  
Adult Life ◽  
Population Based ◽  
Obese Women ◽  
Adverse Health Outcomes ◽  
Lower Lung

IntroductionBreathlessness is common in the population, especially in women and associated with adverse health outcomes. Obesity (body mass index (BMI) >30 kg/m2) is rapidly increasing globally and its impact on breathlessness is unclear.MethodsThis population-based study aimed primarily to evaluate the association of current BMI and self-reported change in BMI since age 20 with breathlessness (modified Research Council score ≥1) in the middle-aged population. Secondary aims were to evaluate factors that contribute to breathlessness in obesity, including the interaction with spirometric lung volume and sex.ResultsWe included 13 437 individuals; mean age 57.5 years; 52.5% women; mean BMI 26.8 (SD 4.3); mean BMI increase since age 20 was 5.0 kg/m2; and 1283 (9.6%) reported breathlessness. Obesity was strongly associated with increased breathlessness, OR 3.54 (95% CI, 3.03 to 4.13) independent of age, sex, smoking, airflow obstruction, exercise level and the presence of comorbidities. The association between BMI and breathlessness was modified by lung volume; the increase in breathlessness prevalence with higher BMI was steeper for individuals with lower forced vital capacity (FVC). The higher breathlessness prevalence in obese women than men (27.4% vs 12.5%; p<0.001) was related to their lower FVC. Irrespective of current BMI and confounders, individuals who had increased in BMI since age 20 had more breathlessness.ConclusionBreathlessness is independently associated with obesity and with weight gain in adult life, and the association is stronger for individuals with lower lung volumes.

Total gestational weight gain and the risk of preeclampsia by pre-pregnancy body mass index categories: a population-based cohort study from 2013 to 2017

2019 ◽  
Vol 47 (6) ◽  
pp. 585-591 ◽  
Author(s):  
Tanja Premru-Srsen ◽  
Zorana Kocic ◽  
Vesna Fabjan Vodusek ◽  
Ksenija Geršak ◽  
Ivan Verdenik
Keyword(s):  
Body Mass Index ◽  
Weight Gain ◽  
Gestational Weight Gain ◽  
Body Mass ◽  
Odds Ratio ◽  
Protective Factor ◽  
Population Based ◽  
Normal Weight ◽  
Obese Women ◽  
Gestational Weight

Abstract Background Identifying the risk factors for preeclampsia (PE) is essential for the implementation of preventive actions. In the present study, we aimed at exploring the association between total gestational weight gain (GWG) and PE. Methods We performed a population-based cohort survey of 98,820 women with singleton pregnancies who delivered in Slovenia from 2013 to 2017. Aggregated data were obtained from the National Perinatal Information System (NPIS). The main outcome measure was the incidence of PE. The main exposure variable was total GWG standardized for the gestational duration by calculating the z-scores. The associations between total GWG and PE stratified by pre-pregnancy body mass index (BMI) categories adjusted for a variety of covariates were determined using multivariable logistic regression. We calculated the crude odds ratio (OR) and adjusted odds ratio (aOR) with a 95% confidence interval using a two-way test. Results Excessive GWG was associated with increased odds of PE in all pre-pregnancy BMI categories. The increase in the odds of PE by 445% was the highest in underweight women and by 122% was the lowest in obese women. Low GWG was associated with decreased odds of PE in all pre-pregnancy BMI categories except in normal-weight women with a GWG below −2 standard deviation (SD) and underweight women. The decrease in the odds of PE by 67% was the highest in obese women and by 41% was the lowest in normal-weight women. Conclusion Excessive GWG is a significant risk factor for PE, especially in underweight women, while low GWG is an important protective factor against PE, especially in obese women.

scholarly journals Prevalence of Obesity and the Relationship between the Body Mass Index and Body Fat: Cross-Sectional, Population-Based Data

PLoS ONE ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. e29580 ◽  
Author(s):  
Julie A. Pasco ◽  
Geoffrey C. Nicholson ◽  
Sharon L. Brennan ◽  
Mark A. Kotowicz
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Body Fat ◽  
Population Based ◽  
The Body ◽  
Cross Sectional ◽  
Prevalence Of Obesity ◽  
The Relationship

scholarly journals Perception of Body Image and Dietary Habit Among Adults Aged 20–45 Years at Sunyani Metropolis

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 277-277
Author(s):  
Jacob Setorglo ◽  
Philip Narteh Gorleku ◽  
Kyei Roselyn ◽  
Kingsley Kwadwo Asare Pereko
Keyword(s):  
Body Mass Index ◽  
Body Image ◽  
Body Size ◽  
Body Mass ◽  
Who Classification ◽  
The Body ◽  
World Health ◽  
Outcome Variable ◽  
Sugar Consumption ◽  
Normal Body

Abstract Objectives The study assessed the body size perception of respondents against the WHO body mass index and related the body sizes to fat and sugar consumption among 20–45-year-old adults. Methods The study design was a descriptive cross-sectional survey which involved 200 respondents aged 20–45 years, sampled conveniently. at Sunyani. Data on socio-demographic, fat and sugar consumption, anthropometry (weight in kg, height in cm) were collected. The weight and height data were later converted into body mass index using the World Health Organisation (WHO) classification. Sugar and fat intakes were measured by dietary food based assessment. (Analysis was done using IBM SPSS version 25. Proportions were presented for categorical values. Chi square test of association was used to determine relationship between the independent and the dependent outcome variable. Statistical significant was set at and P &lt; 0.05. Results The mean age of the respondents was 35 years. About 35.0% of respondents were males and the rest 65.0% females. Sugar and fat consumption among the respondents were within the recommended dietary allowances. Although 75% of respondents had normal body mass index (kg/m2) and 21% were obese based on the WHO classification, Majority (43.0%) of them perceived their body weights were normal. About 48.1% perceived they are either obese or had normal body size. There was no statistically significant association between respondents’ perceived body image and socio-demographic characteristics except for marital status (X2 = 8.82, P = 0.044). There was no statistically significant association between body image perception and dietary intake of fat and sugar. Conclusions There is great disparity in the perception of respondents body image compared to the WHO classification and married women and men are more particular about how they look. Dietary components studied do not have any association with body image. Funding Sources None.

scholarly journals Sex hormones, inflammation and the metabolic syndrome: a population-based study

2003 ◽  
pp. 601-608 ◽  
Author(s):  
DE Laaksonen ◽  
L Niskanen ◽  
K Punnonen ◽  
K Nyyssonen ◽  
TP Tuomainen ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Sex Hormones ◽  
Free Testosterone ◽  
Population Based ◽  
World Health ◽  
Inverse Association ◽  
The Metabolic Syndrome

OBJECTIVE: Mild hypoandrogenism in men is associated with features of the metabolic syndrome, but the association with the metabolic syndrome itself using an accepted definition has not been described. DESIGN: Men with the metabolic syndrome were identified and testosterone and sex hormone-binding globulin (SHBG) levels were determined in a population-based cohort of 1896 non-diabetic middle-aged Finnish men. RESULTS: Calculated free testosterone and SHBG were 11% and 18% lower (P<0.001) in men with the metabolic syndrome (n=345, World Health Organisation definition). After categorisation by tertiles and adjusting for age and body mass index, total and free testosterone and SHBG were inversely associated with concentrations of insulin, glucose, triglycerides, C-reactive protein (CRP) and CRP-adjusted ferritin and positively associated with high-density lipoprotein cholesterol. Men with free testosterone levels in the lowest third were 2.7 (95% confidence interval (CI) 2.0-3.7) times more likely to have the metabolic syndrome in age-adjusted analyses, and 1.7 (95% CI 1.2-2.4) times more likely even after further adjusting for body mass index. Exclusion of men with cardiovascular disease did not alter the association. The inverse association of SHBG with the metabolic syndrome was somewhat stronger. CONCLUSIONS: Low testosterone and SHBG levels were strongly associated not only with components of the metabolic syndrome, but also with the metabolic syndrome itself, independently of body mass index. Furthermore, sex hormones were associated with inflammation and body iron stores. Even in the absence of late-stage consequences such as diabetes and cardiovascular disease, subtle derangements in sex hormones are present in the metabolic syndrome, and may contribute to its pathogenesis.

scholarly journals Clinical verification of body mass index and tumor immune response in patients with breast cancer receiving preoperative chemotherapy

2021 ◽  
Author(s):  
Koji Takada ◽  
Shinichiro Kashiwagi ◽  
Yuka Asano ◽  
Wataru Goto ◽  
Rika Kouhashi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Mass Index ◽  
Body Mass ◽  
Preoperative Chemotherapy ◽  
Early Stage ◽  
The Body ◽  
World Health ◽  
Cancer Type ◽  
Immune Microenvironment ◽  
Tumor Immune Microenvironment

Abstract Purpose: The body mass index (BMI) is commonly used as a simple indicator of obesity; patients with early-stage breast cancer who are obese (OB) per BMI measurements have been shown to have high postoperative recurrence and low survival rates. On the other hand, it has been shown that lymphocytes present in the vicinity of malignant growths that are involved in the tumors’ immune responses influence the efficacy chemotherapy. Therefore, we hypothesized that OB patients with breast cancer have a lower density of tumor-infiltrating lymphocytes (TILs), which may influence the therapeutic effect of preoperative chemotherapy (POC). In this study, we measured pretreatment BMI and TILs in patients with breast cancer who underwent POC, examined the correlations between these two factors, and retrospectively analyzed their therapeutic outcomes and prognoses.Methods: The participants in this study were 421 patients with breast cancer who underwent surgical treatment after POC between February 2007 and January 2019. The patient’s height and weight were measured before POC to calculate the BMI (weight [kg] divided by the square of the height [m2]). According to the World Health Organization categorization, patients who weighed under 18.5 kg/m2 were classified as underweight (UW), those ≥18.5 kg/m2 and >25 kg/m2 were considered normal weight (NW), those ≥25 kg/m2 and <30 kg/m2 were overweight (OW), and those ≥30 kg/m2 were OB. The TILs were those lymphocytes that infiltrated the tumor stroma according to the definition of the International TILs Working Group 2014.Results: The median BMI was 21.9 kg/m2 (range, 14.3–38.5 kg/m2); most patients (244; 64.5%) were NW. Among all 378 patients with breast cancer, the TIL density was significantly lower in OB than in NW and OW patients (vs. NW: p=0.001; vs. OW: p=0.003). Furthermore, when examining patients with each breast cancer type individually, the OS of those with TNBC who had low BMIs was significantly poorer than that of their high-BMI counterparts (log rank p=0.031).Conclusions: Our data did not support the hypothesis that obesity affects the tumor immune microenvironment; however, we showed that being UW does affect the tumor immune microenvironment.

scholarly journals Association between the body mass index and chronic kidney disease in men and women. A population-based study from Israel

2013 ◽  
Vol 28 (suppl 4) ◽  
pp. iv130-iv135 ◽  
Author(s):  
E. Cohen ◽  
A. Fraser ◽  
E. Goldberg ◽  
G. Milo ◽  
M. Garty ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Body Mass ◽  
Population Based ◽  
The Body ◽  
Population Based Study ◽  
Men And Women

scholarly journals Influence of different body mass index cut-off values in assessing the nutritional status of adolescents in a household survey

2009 ◽  
Vol 25 (8) ◽  
pp. 1850-1857 ◽  
Author(s):  
Fabio da Silva Gomes ◽  
Luiz Antonio dos Anjos ◽  
Mauricio Teixeira Leite de Vasconcellos
Keyword(s):  
Body Mass Index ◽  
Nutritional Status ◽  
Body Mass ◽  
Task Force ◽  
Household Survey ◽  
Population Based ◽  
Female Adolescent ◽  
World Health ◽  
Adolescent Population ◽  
Health Organization

The purpose of this study was to evaluate the anthropometric nutritional status of the adolescent population of Niterói, Rio de Janeiro State, Brazil, and the influence of changes in the adopted body mass index (BMI) cut-offs in the nutritional status assessment of the adolescent population. A population-based survey conducted in 2003 obtained data from a probabilistic sample of 1,734 households and 523 adolescents. The multiple proportions test and prevalence ratios were used to analyze differences between estimates obtained from different BMI cut-offs. Changes in cut-off values from the old to the new recommendation of the World Health Organization (WHO) resulted in a significant increase in overweight prevalence among total, male and female adolescent population (25%, 27% and 23%, respectively) (p < 0.05). There were significant increases in the prevalence of low-BMI-for-age among the total (29% increase) and male (39%) adolescent populations when the proposal of the International Obesity Task Force was compared to current WHO BMI-for-age cut-offs (p < 0.05). It is shown that a simple change in cut-off values used to define the anthropometric nutritional status can significantly modify the nutritional profile of an adolescent population.

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