scholarly journals Performance in daily activities, cognitive impairment and perception in multiple sclerosis patients and their caregivers

BMC Neurology ◽  
2018 ◽  
Vol 18 (1) ◽  
Author(s):  
G. Fenu ◽  
M. Fronza ◽  
L. Lorefice ◽  
M. Arru ◽  
G. Coghe ◽  
...  
Author(s):  
Carmen Gutiérrez-Cruz ◽  
F.Javier Rojas-Ruiz ◽  
Juan Carlos De la Cruz-Márquez ◽  
Marcos Gutiérrez-Dávila

This study investigated the effects of a 24-week combined training program (CTP) based on strength exercises and cognitive–motor tasks performed concurrently in participants with multiple sclerosis. A randomized, controlled intervention study was carried out. In total, 31 subjects with a confirmed diagnosis of multiple sclerosis (14 men and 17 women) were stratified and randomized into an intervention group (17 subjects) and a control group (14 subjects). The intervention group completed three weekly training sessions for 24 weeks, while the control group pursued their normal daily activities. In this program, cognitive–motor tasks were completed at once (dual tasking). A 3D photogrammetry connected to a selective attention system designed for dual tasking while walking was used. Ground reaction forces were measured using two force plates, one for sit-to-stand testing, while the other was used for static force measurement. Postural equilibrium was examined using a stabilometric plate based for Romberg test assessment. The 24-week training program for multiple sclerosis patients improved their static peak force by 11% (p < 0 .05), their rate of force development by 36% (p < 0.05), and their balance (p < 0.05). Performance in daily activities such as walking or sitting-to-standing improved significantly in multiple sclerosis participants. CTP training was effective in reducing the dual-task costs of step length (48%) and walking velocity (54%), as compared to a matched control group.


PLoS ONE ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. e30627 ◽  
Author(s):  
Karine Baumstarck ◽  
Jean Pelletier ◽  
Valérie Aghababian ◽  
Françoise Reuter ◽  
Irina Klemina ◽  
...  

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M F Zakaria ◽  
T A Abdo ◽  
A A Abdelaziz ◽  
D A Zamzam ◽  
Y A Abdullah ◽  
...  

Abstract Background Approximately half of all patients with multiple sclerosis (MS) experience cognitive impairment, most commonly with regard to new learning and memory. Cognitive dysfunction is a leading cause of disability in MS and it can have profound social and economic consequences for patients and their families. Objective This study was conducted to discover the early cognitive domains affected in multiple sclerosis patients concomitant with the postulated brain atrophy in an Egyptian sample of multiple sclerosis patients. Patients and Methods A cross-sectional observational case-control study conducted on seventy (60) patients who came for follow-up in Ain Shams University hospitals. 40 patients were taken as cases that followed up in MS unit in Ain-Shams university hospitals. 20 participants were taken as controls taken from the general medicine clinics age and sex matched to our patient group. An informed written consent was taken from parents of each person included in the study. Results There was a statistically significant difference between the two groups in brain volumetric changes and in the parameters of cognitive assessment Conclusion Early detection and examination of cognitive functions is important for patient evaluation, follow up and treatment regimen used.


2016 ◽  
Vol 6 (3) ◽  
pp. 119-127 ◽  
Author(s):  
Nastaran Majdinasab ◽  
Amir Siahpush ◽  
Seyedeh Khatoon Mousavinejad ◽  
Alireza Malayeri ◽  
Seyed Aidin Sajedi ◽  
...  

2006 ◽  
Vol 245 (1-2) ◽  
pp. 77-85 ◽  
Author(s):  
Agnete Jønsson ◽  
Jente Andresen ◽  
Lars Storr ◽  
Thomas Tscherning ◽  
Per Soelberg Sørensen ◽  
...  

1998 ◽  
Vol 19 (S6) ◽  
pp. S392-S398 ◽  
Author(s):  
A. Solari ◽  
A. Ghezzi ◽  
L. Mendozzi ◽  
G. Filippini ◽  
S. Cifani ◽  
...  

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