scholarly journals Group B streptococci vaginal colonization and drug susceptibility pattern among pregnant women attending in selected public antenatal care centers in Addis Ababa, Ethiopia

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Solomon Assefa ◽  
Kassu Desta ◽  
Tsehaynesh Lema
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Addis Ababa ◽  
Drug Susceptibility ◽  
Susceptibility Pattern ◽  
Group B Streptococci ◽  
Vaginal Colonization ◽  
Drug Susceptibility Pattern ◽  
Group B

scholarly journals Group B Streptococcus Recto-Vaginal Colonization in Near-Term Pregnant Women, Southwest Ethiopia

2020 ◽  
Vol 30 (5) ◽  
Author(s):  
Woubishet Girma ◽  
Nadia Yimer ◽  
Tesfaye Kassa ◽  
Elias Yesuf
Keyword(s):  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Group B Streptococcus ◽  
Susceptibility Pattern ◽  
Southwest Ethiopia ◽  
Vaginal Colonization ◽  
History Of ◽  
Near Term ◽  
Group B

BACKGROUND: Group B Streptococcus (GBS) is recognized as an important cause of maternal and neonatal morbidity and mortality. Maternal vaginal carriage of GBS (Streptococcus agalactiae) can lead to vertical transmission to the neonate at the time of delivery. However, little is known about its prevalence, predictors and antibiotic susceptibility pattern in Jimma, Ethiopia. This study assessed the prevalence, antimicrobial susceptibility pattern and determinants of GBS recto-vaginal colonization among near-term pregnant women.METHODS: A cross-sectional study was conducted from May to August 2015 at Jimma University Medical Centre in Southwest Ethiopia. Data through questionnaire and GBS isolates from vaginal and rectal swabs were collected. Antimicrobial susceptibility testing was performed.RESULTS: The overall prevalence of GBS colonization among near term pregnant women (35-37 weeks) was 16.3% (22/135). The majority of GBS isolates were sensitive to Ampicillin and Penicillin G with 95.5% and 90.1%, respectively. Erythromycin and clindamycin were resisted by 50% and 40.9% of the isolates, respectively, whereas gentamicin was resisted by all isolates. GBS colonization was significantly associated with a history of preterm delivery (PTD) (AOR: 6.3, 95% CI: 1.42, 28.3) and history of urinary tract infection (UTI) during current pregnancy (AOR: 6.4, 95% CI, 1.95, 21.1).CONCLUSION: Our study indicated that one among six near-term pregnant women had recto-vaginal GBS colonization. In places where universal screening is not feasible, selective screening for factors particularly history of PTD and UTI during current pregnancy may be a reasonable option. Antibiotic susceptibility testing should be performed while using Erythromycin, Clindamycin or Gentamicin. 

scholarly journals Asymptomatic Bacteriuria Bacterial Profile and Antibiotic Susceptibility Pattern Among Pregnant Women Attending Antenatal Care (Anc) Clinic of Assosa General Hospital, Benishangul Gumuz Region, Western Ethiopia

2020 ◽  
Author(s):  
Duresa Abu Tusuna ◽  
Teferra Abula Orjino
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
General Hospital ◽  
Antimicrobial Susceptibility ◽  
Asymptomatic Bacteriuria ◽  
Susceptibility Pattern ◽  
Group B Streptococci ◽  
Biochemical Tests ◽  
Care Clinic ◽  
Western Ethiopia

Abstract Background: ASB is a common problem in pregnant women and about 40% of women with untreated asymptomatic bacteriuria during pregnancy develop pyelonephritis, which might lead to low birth weight, preterm, premature rupture of membranes and preterm labour. Therefore, this study aimed to assess the prevalence of asymptomatic bacteriuria, antimicrobial susceptibility pattern of the isolates among pregnant women attending antenatal care clinic of Assosa General Hospital, western Ethiopia.Methods: A facility-based cross sectional study was conducted from January to February 2019. Well-mixed and uncentrifuged urine specimens obtained from the pregnant women was directly inoculated on cystine lactose electrolyte deficient agar (CLED) (Oxoid, Ltd, England) media by streak plate method. Bacterial isolates were identified as per the standard bacteriological procedure using colony characteristics, gram-staining, and series of biochemical tests. Antimicrobial susceptibility test was carried out by Kirby- Bauer disk diffusion technique on Muller-Hinton agar medium and the diameter of zone of inhibition was interpreted according toClinical Laboratory Standard Institute (CLSI) guidelinesResult: The overall prevalence of ASB among pregnant women in this study was 14.85%.E. coli was the most predominant isolate (50 %,) followed by K. pneumoniae (16.7%,), S. aureus (14.3%), coagulase negative staphylococci (CONS) (11.9%), and group B streptococci (GBS) (7.1%).Gram-negative bacteria were highly resistant for tetracycline (96.4%), ampicillin .Gram-positive bacteria were 100% sensitive for ceftazidime. Conclusion: Significant bacteriuria was observed in asymptomatic pregnant women. Therefore, routine laboratory diagnosis of ASB in pregnant women and providing appropriate treatment should be needed to reduce its complications.

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