scholarly journals Antibiotic prescribing in paediatric inpatients in Ghana: a multi-centre point prevalence survey

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Appiah-Korang Labi ◽  
Noah Obeng-Nkrumah ◽  
Gifty Sunkwa-Mills ◽  
Antoinette Bediako-Bowan ◽  
Christiana Akufo ◽  
...  
Keyword(s):  
Point Prevalence ◽  
Antibiotic Prescribing ◽  
Prevalence Survey ◽  
Point Prevalence Survey

scholarly journals A prospective antibiotic point prevalence survey in two primary referral hospitals during and after pilgrims stay in Madinah, Saudi Arabia

2020 ◽  
Vol 19 (2) ◽  
pp. 391-399
Author(s):  
Yaser M. ◽  
Ahmad K. Aljabri ◽  
Faisal N. Alsaadi ◽  
Lamiaa M. Rizk ◽  
Renad Y. Alahmadi ◽  
...  
Keyword(s):  
Quality Improvement ◽  
Antibiotic Therapy ◽  
Prevalence Rate ◽  
Antibiotic Use ◽  
Point Prevalence ◽  
Antibiotic Prescribing ◽  
Prevalence Survey ◽  
Point Prevalence Survey ◽  
Significant Difference ◽  
Referral Hospitals

Purpose: To assess current patterns of antibiotic use by carrying out two point-prevalence surveys (PPS) in Madinah after the return of hajj pilgrims from Makkah and when Madinah is free from pilgrims. Methods: In September 2016 and November 2016, a prospective PPS was conducted on two separate dates (during the hajj pilgrims stay in Madinah and after they leave). Data on antibiotics use were generated during these two periods. This involved an audit from all the departments of two referral hospitals (King Fahad Hospital (KFH) - 425 beds, and Al Ansar Hospital - 100 beds) of inpatients records. Data were collected using standard forms adapted from the European Centre for Disease Control (ECDC). Results: A total of 675 inpatients were included in PPS; among them, 332 (49.18 %) patients were receiving antibiotic therapy. In September 2016, 168 patients were treated with antibiotics, with a prevalence rate of 50.60 %, whereas, in November 2016, the prevalence rate was 49.40 %. Overall, 198 patients were identified in surgical wards, of which 132 patients (66.6 %) were receiving antibiotic therapy; 121 patients in ICU of which 70 patients (57.8 %) received antibiotics; 13 patients in other wards of which 6 (46.1 %) received antibiotic treatment; and 343 patients in medical wards of which 126 patients (36.7 %) were treated with antibiotics. There was no significant difference in prevalence of antibiotic prescribing between the two surveys (Pearson Chi-square test, p = 0.56) and with regards to patient age between the two surveys (Mann-Whitney U-test, p = 0.32). Conclusion: The results demonstrate that antibiotic use with adherence to hospital guidelines and PPS helps in identifying targets for quality improvement. Moreover, to escalate the prudent use of antibiotics in hospitals, PPS provides a useful tool. Furthermore, this survey provides a background to evaluate antibiotic use by a standardized methodology. Keywords: Point prevalence survey, Antibiotic use, Prescribing practices, Antibiotic resistance, Quality improvement, Antibiotic stewardship, Hajj, Pilgrims

scholarly journals Antimicrobial Consumption and Resistance in a Tertiary Care Hospital in Jordan: Results of an Internet-Based Global Point Prevalence Survey

Antibiotics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 598
Author(s):  
Khawla Abu Hammour ◽  
Esraa AL-Heyari ◽  
Aya Allan ◽  
Ann Versporten ◽  
Herman Goossens ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Point Prevalence ◽  
Antibiotic Prescribing ◽  
Prescription Data ◽  
Care Hospital ◽  
Antimicrobial Consumption ◽  
Healthcare Associated Infection ◽  
Prevalence Survey ◽  
Point Prevalence Survey ◽  
Healthcare Associated

Background: The Global Point Prevalence Survey (Global-PPS) provides a standardised method to conduct surveillance of antimicrobial prescribing and resistance at hospital level. The aim of the present study was to assess antimicrobial consumption and resistance in a Jordan teaching hospital as part of the Global-PPS network. Methods: Detailed antimicrobial prescription data were collected according to the Global Point Prevalence Survey protocol. The internet-based survey included all inpatients present at 8:00 am on a specific day in June–July 2018. Resistance data were based on microbiological results available on the day of the PPS. Results: Data were collected for 380 patients admitted to adult wards, 72 admitted children, and 36 admitted neonates. The overall prevalence of antimicrobial use in adult, paediatric, and neonatal wards was 45.3%, 30.6%, and 22.2% respectively. Overall, 36 patients (7.4%) were treated for at least one healthcare-associated infection (HAI). The most frequent reason for antimicrobial treatment was pneumonia. Cephalosporins and carbapenems were most frequent prescribed among adult (50.6%) and paediatric/neonatal wards (39.6%). Overall resistance rates among patients treated for a community or healthcare-associated infection was high (26.0%). Analysis of antibiotic quality indicators by activity revealed good adherence to treatment guidelines but poor documentation of the reason for prescription and a stop/review date in the notes. Conclusion: The present study has established baseline data in a teaching hospital regarding the quantity and quality of prescribed antibiotics in the hospital. The study should encourage the establishment of tailor-made antimicrobial stewardship interventions and support educational programs to enhance appropriate antibiotic prescribing.

scholarly journals A multicentre point prevalence survey of patterns and quality of antibiotic prescribing in Indonesian hospitals

2021 ◽  
Author(s):  
Ralalicia Limato ◽  
Erni J. Nelwan ◽  
Manzilina Mudia ◽  
Justin de Brabander ◽  
Helio Guterres ◽  
...  
Keyword(s):  
Point Prevalence ◽  
High Rate ◽  
Antibiotic Prescribing ◽  
Gastrointestinal Infections ◽  
Prevalence Survey ◽  
Hospital Acquired Infection ◽  
Point Prevalence Survey ◽  
Hospital Acquired ◽  
Third Generation Cephalosporins

SynopsisBackgroundAntibiotic misuse and overuse are a major driver of antimicrobial resistance, but systematic data in Indonesia are scarce.ObjectivesTo evaluate patterns and quality indicators of antibiotic prescribing in six acute-care hospitals in Jakarta, Indonesia.MethodsWe conducted a hospital-wide point prevalence survey (PPS) between March and August 2019, using Global-PPS and WHO-PPS protocols. The analysis focused on antibacterials for systemic use (antibiotics).ResultsOf 1602 inpatients, 993 (62.0%) received ≥1 antimicrobials. Of 1666 antimicrobial prescriptions, 1273 (76.4%) were antibiotics. Most common reasons for prescribing were pneumonia (27.7%), skin and soft tissue infections (8.3%), gastrointestinal prophylaxis (7.9%), and gastrointestinal infections (5.4%). The most common indication was community-acquired infection (42.6%), followed by surgical prophylaxis (22.6%), hospital-acquired infection (18.5%), medical prophylaxis (9.6%), unknown (4.6%) and other indications (2.1%). The most prescribed antibiotic classes were third-generation cephalosporins (44.3%), fluoroquinolones (13.5%), carbapenems (7.4%), penicillins with B-lactamase inhibitor (6.8%) and aminoglycosides (6.0%). According to the WHO AWaRe classification, Watch antibiotics accounted for 67.4%, followed by 28.0% Access, 2.4% Reserve, and 2.2% Unclassified. Reason for prescribing, stop/review date and planned duration were poorly documented. Hospital antibiotic guidelines were not available for 28.1% of prescriptions, and guideline compliance was 52.2% (478/915). Parenteral administration was high (85.1%). Targeted (non-empirical) prescriptions comprised 8.1% (44/542) for community-acquired infections and 26.8% (63/235) for hospital-acquired infections.ConclusionsOur data indicate a high rate of parenteral, empiric use of broad-spectrum antibiotics in Indonesian hospitals, coupled with poor documentation and guideline adherence. The findings suggest important areas for antimicrobial stewardship interventions.

scholarly journals Point Prevalence Survey of Antibiotic Prescribing in the Hospital Sector in Albania

2021 ◽  
Vol 59 (4) ◽  
pp. 533-547
Author(s):  
Silvi Bozo ◽  
Carlo De Giuli Morghen ◽  
Elena Capparelli ◽  
Eftiola Pojani
Keyword(s):  
Point Prevalence ◽  
Antibiotic Prescribing ◽  
Prevalence Survey ◽  
Hospital Sector ◽  
Point Prevalence Survey

scholarly journals 2018. The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance: Quantity and Quality of Antimicrobial Prescribing for Inpatients with Pneumonia in the Philippines in 2018

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S677-S677
Author(s):  
Mari Rose Aplasca De los Reyes ◽  
Maria Charmian M Hufano ◽  
Ines Pauwels ◽  
Ann Versporten ◽  
Herman Goossens
Keyword(s):  
Enzyme Inhibitor ◽  
The Philippines ◽  
Community Acquired Pneumonia ◽  
Point Prevalence ◽  
Antibiotic Prescribing ◽  
Prevalence Survey ◽  
Public And Private ◽  
Point Prevalence Survey ◽  
Stewardship Program

Abstract Background Pneumonia is the most common indication for prescription of antibiotics in hospitals in the Philippines. We describe the quality and quantity of antibiotic prescribing for hospitalized pneumonia patients in the Philippines in 2018 (www.global-PPS.com). Methods A point prevalence survey was performed from September to December 2018 in 28 public and private hospitals in Luzon, Mindanao, and Visayas regions. Ward- and patient-level data were collected using a standardized methodology and entered through a web-based application. We analyzed all antibiotic (ATC J01) prescriptions for inpatients with pneumonia. Results Of all hospitalized patients, 16.2% (n = 1516) received one or more antibiotic (J01) for treatment of pneumonia, majority (78.3%) of which were for community-acquired pneumonia (CAP). In adults, the most commonly used antibiotics were azithromycin (19.5%), ceftriaxone (19.0%), and piperacillin/enzyme inhibitor (13.2%) for CAP and meropenem (19.8%), piperacillin/enzyme inhibitor (18.9%), and levofloxacin (8.6%) for healthcare-associated pneumonia (HAP). In neonates and children, cefuroxime was used most often (20.1%) for treatment of CAP, followed by ampicillin (16.7%) and amikacin (15.3%). Children and neonates with HAP were most commonly treated with amikacin (18.7%), meropenem (15.7%), and ampicillin (10.4%). Overall, 16.0% of all antibiotic prescriptions for pneumonia were based on microbiological results, 11.3% for CAP and 33.9% for HAP. Microbiology-based prescriptions were most commonly targeted at ESBL-producing Enterobacteriaceae (8.4%). Further analysis of quality indicators showed that up to 80.0% of all prescriptions for pneumonia were compliant to local guidelines and reason in notes was documented for 81.0% of prescriptions. However, the stop or review date of antibiotic treatment for pneumonia was less documented (27.8%). Conclusion Global-PPS data provided valuable insights into the quantity and quality of antibiotic prescribing for pneumonia inpatients. These results will be fedback to the Department of Health, medical societies, and hospitals for prioritization of targets and policies toward the improvement of the Philippine antimicrobial stewardship program. Disclosures All authors: No reported disclosures.

scholarly journals Antibiotic Prescribing Patterns at COVID-19 Dedicated Wards in Bangladesh: A Single Center Point-Prevalence Survey

2021 ◽  
Author(s):  
Md. Maruf Ahmed Molla ◽  
Mahmuda Yeasmin ◽  
Md. Khairul Islam ◽  
Md. Mohiuddin Sharif ◽  
Mohammad Robed Amin ◽  
...  
Keyword(s):  
Antibiotic Usage ◽  
Health Care Facilities ◽  
Point Prevalence ◽  
Prescribing Patterns ◽  
Fisher Exact Test ◽  
Antibiotic Prescribing ◽  
Prevalence Survey ◽  
Health Crisis ◽  
Point Prevalence Survey ◽  
Usage Data

SummaryThere is a clear deficiency in antimicrobial usage data and ongoing stewardship programs both in government and private health care facilities in Bangladesh. As evidences are mounting regarding irrational and often unnecessary use of antibiotics during COVID-19 pandemic, a point prevalence survey (PPS) was conducted across COVID-19 dedicated wards in Dhaka Medical College and Hospital (DMCH). Antibiotic usage data were collected from 193 patients at different COVID-19 dedicated wards at DMCH between 21 May, 2020 and 10 June, 2020. Comparisons in antibiotic usage were made between different groups using Pearson chi-square and Fisher exact test. Factors associated with multiple antibiotic prescription were evaluated using binary logistic regression model.On survey date all (100%) patients were receiving at least one antibiotic with 133 patients (68.91%) receiving multiple antibiotics. Overall, patients presenting with severe disease received more antibiotics on average. Third generation cephalosporin ceftriaxone (53.8%), meropenem (40.9%), moxifloxacin (29.5%) and doxycycline (25.4%) were the four most prescribed antibiotics among survey patients. Among comorbidities diabetes mellitus (DM) was independently associated with increased antibiotic prescribing. Abnormal C-reactive protein (CRP) and serum d-dimer were linked with higher odds of antibiotic prescribing among survey patients. Overall, prevalence of antibiotic prescribing in COVID-19 patients at DMCH was very high. This could be attributed to a lack of clear treatment protocol against COVID-19 till date as well as lack of modern laboratory facilities to support judicial antibiotic prescribing in Bangladesh. A well-functioning antibiotic stewardship program in Bangladesh is required to prevent an impending health crisis.

scholarly journals Appropriateness of Antibiotic Prescribing in U. S. Children’s Hospitals: A National Point Prevalence Survey

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S497-S498 ◽  
Author(s):  
Alison Tribble ◽  
Brian Lee ◽  
Lori Handy ◽  
Jeffrey S Gerber ◽  
Adam L Hersh ◽  
...  
Keyword(s):  
Point Prevalence ◽  
Antibiotic Prescribing ◽  
Children's Hospitals ◽  
Prevalence Survey ◽  
Point Prevalence Survey ◽  
Children’S Hospitals

scholarly journals A multicentre point prevalence survey of patterns and quality of antibiotic prescribing in Indonesian hospitals

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Ralalicia Limato ◽  
Erni J Nelwan ◽  
Manzilina Mudia ◽  
Justin de Brabander ◽  
Helio Guterres ◽  
...  
Keyword(s):  
Antibiotic Prescription ◽  
Point Prevalence ◽  
High Rate ◽  
Antibiotic Prescribing ◽  
Prevalence Survey ◽  
Hospital Acquired Infections ◽  
Point Prevalence Survey ◽  
Hospital Acquired ◽  
Third Generation Cephalosporins

Abstract Background The global emergence of antimicrobial resistance is driven by antibiotic misuse and overuse. However, systematic data in Indonesian hospitals to adequately inform policy are scarce. Objectives To evaluate patterns and quality indicators of antibiotic prescribing in six general hospitals in Jakarta, Indonesia. Methods We conducted a hospital-wide point prevalence survey (PPS) between March and August 2019, using Global-PPS and WHO-PPS protocols. The analysis focused on antibacterials (antibiotics) for systemic use. Results Of 1602 inpatients, 993 (62.0%) received ≥1 antimicrobial. Of 1666 antimicrobial prescriptions, 1273 (76.4%) were antibiotics. Indications comprised community-acquired infections (42.6%), surgical prophylaxis (22.6%), hospital-acquired infections (18.5%), medical prophylaxis (9.6%), unknown (4.6%) and other (2.1%). The most common reasons for antibiotic prescribing were pneumonia (27.7%), skin and soft tissue infections (8.3%), and gastrointestinal prophylaxis (7.9%). The most prescribed antibiotic classes were third-generation cephalosporins (44.3%), fluoroquinolones (13.5%), carbapenems (7.4%), and penicillins with β-lactamase inhibitor (6.8%). According to the WHO AWaRe classification, Watch antibiotics accounted for 67.4%, followed by 28.0% Access and 2.4% Reserve. Hospital antibiotic guidelines were not available for 28.1% of prescriptions, and, where available, guideline compliance was 52.2%. Reason for the antibiotic prescription, stop/review date and planned duration were poorly documented. Culture-guided prescriptions comprised 8.1% of community-acquired infections and 26.8% of hospital-acquired infections. Conclusions Our data indicate a high rate of empirical use of broad-spectrum antibiotics in Indonesian hospitals, coupled with poor documentation and guideline adherence. The findings suggest important areas for antimicrobial stewardship interventions.

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