scholarly journals Moderated online social therapy for carers of young people recovering from first-episode psychosis: study protocol for a randomised controlled trial

Trials ◽  
2017 ◽  
Vol 18 (1) ◽  
Author(s):  
John Gleeson ◽  
Reeva Lederman ◽  
Helen Herrman ◽  
Peter Koval ◽  
Dina Eleftheriadis ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Young People ◽  
Study Protocol ◽  
Controlled Trial ◽  
First Episode Psychosis ◽  
First Episode ◽  
Social Therapy ◽  
Episode Psychosis ◽  
Randomised Controlled

Suicide Prevention in First Episode Psychosis: The Development of a Randomised Controlled Trial of Cognitive Therapy for Acutely Suicidal Patients With Early Psychosis

2003 ◽  
Vol 37 (4) ◽  
pp. 414-420 ◽  
Author(s):  
P.J.R. Power ◽  
R.J. Bell ◽  
R. Mills ◽  
T. Herrman-Doig ◽  
M. Davern ◽  
...  
Keyword(s):  
Early Intervention ◽  
Treatment Group ◽  
Young People ◽  
Controlled Trial ◽  
First Episode Psychosis ◽  
Early Psychosis ◽  
First Episode ◽  
Episode Psychosis ◽  
Randomised Controlled ◽  
Suicidal Patients

Background: Young people with early psychosis are at particularly high risk of suicide. However, there is evidence that early intervention can reduce this risk. Despite these advances, first episode psychosis patients attending these new services still remain at risk. To address this concern, a program called LifeSPAN was established within the Early Psychosis Prevention and Intervention Centre (EPPIC). The program developed and evaluated a number of suicide prevention strategies within EPPIC and included a cognitively oriented therapy (LifeSPAN therapy) for acutely suicidal patients with psychosis. We describe the development of these interventions in this paper. Method: Clinical audit and surveys provided an indication of the prevalence of suicidality among first episode psychosis patients attending EPPIC. Second, staff focus groups and surveys identified gaps in service provision for suicidal young people attending the service. Third, a suicide risk monitoring system was introduced to identify those at highest risk. Finally, patients so identified were referred to and offered LifeSPAN therapy whose effectiveness was evaluated in a randomised controlled trial. Results: Fifty-six suicidal patients with first episode psychosis were randomly assigned to standard clinical care or standard care plus LifeSPAN therapy. Forty-two patients completed the intervention. Clinical ratings and measures of suicidality and risk were assessed before, immediately after the intervention, and 6 months later. Benefits were noted in the treatment group on indirect measures of suicidality, e.g., hopelessness. The treatment group showed a greater average improvement (though not significant) on a measure of suicide ideation. Conclusions: Early intervention in psychosis for young people reduces the risk of suicide. Augmenting early intervention with a suicide preventative therapy may further reduce this risk.

scholarly journals HORYZONS trial: protocol for a randomised controlled trial of a moderated online social therapy to maintain treatment effects from first-episode psychosis services

BMJ Open ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. e024104 ◽  
Author(s):  
Mario Alvarez-Jimenez ◽  
Sarah Bendall ◽  
Peter Koval ◽  
Simon Rice ◽  
Daniela Cagliarini ◽  
...  
Keyword(s):  
Social Media ◽  
Randomised Controlled Trial ◽  
Social Functioning ◽  
Controlled Trial ◽  
First Episode Psychosis ◽  
First Episode ◽  
Online Social Media ◽  
Regular Care ◽  
Episode Psychosis ◽  
Randomised Controlled

IntroductionSpecialised early intervention services have demonstrated improved outcomes in first-episode psychosis (FEP); however, clinical gains may not be sustained after patients are transferred to regular care. Moreover, many patients with FEP remain socially isolated with poor functional outcomes. To address this, our multidisciplinary team has developed a moderated online social media therapy (HORYZONS) designed to enhance social functioning and maintain clinical gains from specialist FEP services. HORYZONS merges: (1) peer-to-peer social networking; (2) tailored therapeutic interventions; (3) expert and peer-moderation; and (4) new models of psychological therapy (strengths and mindfulness-based interventions) targeting social functioning. The aim of this trial is to determine whether following 2 years of specialised support and 18-month online social media-based intervention (HORYZONS) is superior to 18 months of regular care.Methods and analysisThis study is a single-blind randomised controlled trial. The treatment conditions include HORYZONS plus treatment as usual (TAU) or TAU alone. We recruited 170 young people with FEP, aged 16–27 years, in clinical remission and nearing discharge from Early Psychosis Prevention and Intervention Centre, Melbourne. The study includes four assessment time points, namely, baseline, 6-month, 12-month and 18-month follow-up. The study is due for completion in July 2018 and included a 40-month recruitment period and an 18-month treatment phase. The primary outcome is social functioning at 18 months. Secondary outcome measures include rate of hospital admissions, cost-effectiveness, vocational status, depression, social support, loneliness, self-esteem, self-efficacy, anxiety, psychological well-being, satisfaction with life, quality of life, positive and negative psychotic symptoms and substance use. Social functioning will be also assessed in real time through our Smartphone Ecological Momentary Assessment tool.Ethics and disseminationMelbourne Health Human Research Ethics Committee (2013.146) provided ethics approval for this study. Findings will be made available through scientific journals and forums and to the public via social media and the Orygen website.Trial registration numberACTRN12614000009617; Pre-results.

scholarly journals Integrated treatment of first episode psychosis with online training (e-learning): study protocol for a randomised controlled trial

Trials ◽  
2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Sara Barbeito ◽  
Patricia Vega ◽  
Sonia Ruiz de Azua ◽  
Vicent Balanza- Martinez ◽  
Francesc Colom ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Online Training ◽  
First Episode Psychosis ◽  
Integrated Treatment ◽  
First Episode ◽  
Learning Study ◽  
Episode Psychosis ◽  
E Learning ◽  
Randomised Controlled

OPUS project: A randomised controlled trial of integrated psychiatric treatment in first episode psychosis

2003 ◽  
Vol 60 (1) ◽  
pp. 297 ◽  
Author(s):  
M. Nordentoft ◽  
P. Jeppesen ◽  
L. Petersen ◽  
A. Thorup ◽  
M. Abel ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Psychiatric Treatment ◽  
Controlled Trial ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis ◽  
Randomised Controlled
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