scholarly journals RED BLOOD CELL (RBC) MEMBRANE DEFORMABILITY AND WHOLE BLOOD VISCOSITY IN INFANTS OF DIABETIC MOTHERS (IDM)

1984 ◽  
Vol 18 ◽  
pp. 341A-341A
Author(s):  
Arun K Pramanik ◽  
Narla Mohandas
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Whole Blood Viscosity ◽  
Infants Of Diabetic Mothers ◽  
Rbc Membrane ◽  
Diabetic Mothers

A physiometer for simultaneous measurement of whole blood viscosity and its determinants: hematocrit and red blood cell deformability

The Analyst ◽  
2019 ◽  
Vol 144 (9) ◽  
pp. 3144-3157 ◽  
Author(s):  
Byung Jun Kim ◽  
Ye Sung Lee ◽  
Alexander Zhbanov ◽  
Sung Yang
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Viscosity ◽  
Simultaneous Measurement ◽  
Whole Blood ◽  
Cell Deformability ◽  
Whole Blood Viscosity ◽  
Red Blood Cell Deformability ◽  
Rbc Deformability

In this study, a microfluidic-based physiometer capable of measuring the whole blood viscosity, hematocrit, and red blood cell (RBC) deformability on a chip is introduced.

scholarly journals Whole blood viscosity and red blood cell adhesion: Potential biomarkers for targeted and curative therapies in sickle cell disease

2020 ◽  
Vol 95 (11) ◽  
pp. 1246-1256 ◽  
Author(s):  
Erdem Kucukal ◽  
Yuncheng Man ◽  
Ailis Hill ◽  
Shichen Liu ◽  
Allison Bode ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Sickle Cell Disease ◽  
Blood Cell ◽  
Sickle Cell ◽  
Red Blood Cell ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Cell Disease ◽  
Whole Blood Viscosity ◽  
Potential Biomarkers

scholarly journals Changes of whole blood viscosity, plasma viscosity and red blood cell filtrability in patients with obese fatty liver in the process of recovery.

1987 ◽  
Vol 13 (1) ◽  
pp. 6-10 ◽  
Author(s):  
HIROYOSHI NAKAMURA ◽  
SATORU KOBAYASHI ◽  
KUNIHIKO OHNISHI ◽  
FUMIO NOMURA ◽  
YOSHIO KANAKUBO ◽  
...  
Keyword(s):  
Blood Cell ◽  
Fatty Liver ◽  
Red Blood Cell ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Plasma Viscosity ◽  
Whole Blood Viscosity

Blood Electrical Impedance Closely Matches Whole Blood Viscosity as Parameter of Hemorheology and Inflammation

2003 ◽  
Vol 13 (6) ◽  
pp. 305-312 ◽  
Author(s):  
G.A.M. Pop ◽  
W.J. Hop ◽  
L. Moraru ◽  
M. van der Jagt ◽  
J. Quak ◽  
...  
Keyword(s):  
Shear Rate ◽  
Blood Cell ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Cell Aggregation ◽  
Whole Blood Viscosity ◽  
Red Blood Cell Aggregation ◽  
Exponential Increase ◽  
Blood Impedance ◽  
Low Shear

AbstractRed blood cell aggregation (RBCa) is a sensitive inflammation marker. RBCa determination from erythrocyte sedimentation rate, ESR, is used since long, but is unspecific unless corrected for hematocrit, Ht. Whole blood viscosity measurement at low shear rate is also sensitive to RBCa but is cumbersome to apply. To investigate whether electrical blood impedance, being sensitive to spatial red cell distribution, can be a good alternative to determine RBCa in low shear conditions. Blood was collected from 7 healthy volunteers. From each 16 different samples were prepared with 4 different Ht’s and with 4 different fibrinogen concentrations. Viscosity was measured at low shear rate (4.04 s-1) with a rotational viscometer at 37˚C. Electrical blood impedance was measured during similar shear conditions and temperature in a specially designed cuvette. ESR was determined according to Westergren. A logarithmic increase of viscosity as well as of capacitance, Cm, is seen when fibrinogen rises and an exponential increase when Ht rises. However, ESR shows a logarithmic decrease with increasing Ht and an exponential increase when fibrinogen rises. The viscosity could be accurately described using an exponential model. Under similar low shear conditions and temperature in-vitro, either whole blood viscosity or electrical blood capacitance reflect red blood cell aggregation due to fibrinogen and Ht variation in a similar way.

Viscosity and Red Cell Deformity in Arterial Disease

1979 ◽  
Author(s):  
G Cella ◽  
H de Haas ◽  
M Rampling ◽  
V Kakkar
Keyword(s):  
Vascular Disease ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Arterial Disease ◽  
Plasma Viscosity ◽  
Control Group ◽  
Fibrinogen Concentration ◽  
Red Cell ◽  
Whole Blood Viscosity ◽  
Significant Difference

Haemorrheological factors have been shown to be affected in many kings of vascular disease. The present study was undertaken to correlate these factors in normal subjects and patients suffering from peripheral arterial disease. Twenty-two patients were investigated; they had moderate or severe intermittent claudication, extent of disease being confirmed by aorto-arteriography and ankle-systolic pressure studies. Twenty-five controls with no symptoms or signs of arterial disease were selected with comparable age and sex distribution. Whole blood viscosity was measured at shear rates of 230 secs-1 and 23 secs-lat 37°c using a Wells Brookfield cone plate microvisco meter. Plasma viscosity was also measured in an identical manner. Erythrocyte flexibility was measured by centrifuge technique and fibrinogen concentration as well as haematocrit by standard techniques. The fibrinogen concentration appeared to be the only significant parameter; the mean concentration in patients with peripheral vascular disease of 463 ± 73mg/l00ml in the control group ( < 0.05). Although whole blood viscosity was high in patients, when corrected to a common haematocrit, there was no significant difference between patients and controls. The same megative correlation was found for plasma viscosity. The red cell flexibility was found to be increased in patients as compared to the control group, but this effect appeared to be simply proportional to the fibrinogen concentration.

In vitro effects of temperature on red blood cell deformability and membrane stability in human and various vertebrate species

2021 ◽  
pp. 1-10
Author(s):  
Adam Attila Matrai ◽  
Gabor Varga ◽  
Bence Tanczos ◽  
Barbara Barath ◽  
Adam Varga ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Whole Blood ◽  
Mechanical Stability ◽  
Cell Deformability ◽  
Blood Samples ◽  
Effects Of Temperature ◽  
The Way ◽  
Rbc Deformability

BACKGROUND: The effects of temperature on micro-rheological variables have not been completely revealed yet. OBJECTIVE: To investigate micro-rheological effects of heat treatment in human, rat, dog, and porcine blood samples. METHODS: Red blood cell (RBC) - buffer suspensions were prepared and immersed in a 37, 40, and 43°C heat-controlled water bath for 10 minutes. Deformability, as well as mechanical stability of RBCs were measured in ektacytometer. These tests were also examined in whole blood samples at various temperatures, gradually between 37 and 45°C in the ektacytometer. RESULTS: RBC deformability significantly worsened in the samples treated at 40 and 43°C degrees, more expressed in human, porcine, rat, and in smaller degree in canine samples. The way of heating (incubation vs. ektacytometer temperation) and the composition of the sample (RBC-PBS suspension or whole blood) resulted in the different magnitude of RBC deformability deterioration. Heating affected RBC membrane (mechanical) stability, showing controversial alterations. CONCLUSION: Significant changes occur in RBC deformability by increasing temperature, showing inter-species differences. The magnitude of alterations is depending on the way of heating and the composition of the sample. The results may contribute to better understanding the micro-rheological deterioration in hyperthermia or fever.

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