A Study of the Role of the Adrenal Glands in the Initiation of the Hiatus in Gonadotropin Secretion during Prepubertal Development in the Male Rhesus Monkey (Macaca mulatto)*

Endocrinology ◽  
1984 ◽  
Vol 114 (2) ◽  
pp. 560-565 ◽  
Author(s):  
T. M. PLANT ◽  
D. S. ZORUB
Keyword(s):  
Rhesus Monkey ◽  
Adrenal Glands ◽  
Gonadotropin Secretion ◽  
Macaca Mulatto ◽  
Male Rhesus

Testosterone and the Control of Gonadotropin Secretion in the Male Rhesus Monkey (Macaca mulatto)*

Endocrinology ◽  
1978 ◽  
Vol 103 (2) ◽  
pp. 535-541 ◽  
Author(s):  
T. M. PLANT ◽  
D. L. HESS ◽  
J. HOTCHKISS ◽  
E. KNOBIL
Keyword(s):  
Rhesus Monkey ◽  
Gonadotropin Secretion ◽  
Macaca Mulatto ◽  
Male Rhesus

scholarly journals Circulating Concentrations of Dimeric Inhibin A and B in the Male Rhesus Monkey (Macaca mulatta)1

1997 ◽  
Vol 82 (8) ◽  
pp. 2617-2621
Author(s):  
T. M. Plant ◽  
V. Padmanabhan ◽  
S. Ramaswamy ◽  
D. S. McConnell ◽  
S. J. Winters ◽  
...  
Keyword(s):  
Rhesus Monkey ◽  
Macaca Mulatta ◽  
Venous Blood ◽  
Peripheral Circulation ◽  
Inhibin B ◽  
Inhibin A ◽  
The Mean ◽  
Juvenile Males ◽  
Male Rhesus

The purpose of this study was to determine the relative concentrations of inhibin A and B in peripheral serum of the adult male rhesus monkey and to examine the testicular contribution to these circulating forms of inhibin. In addition, inhibin B concentrations were also determined in peripheral sera of neonatal and juvenile males and in spermatic vein blood of adults. Immunoradiometric assays specific for the measurement of inhibin A and B were used. These assays also provided an opportunity to reexamine the physiological significance of a replacement infusion of recombinant human (rh)-inhibin A previously employed to study the role of this hormone in regulating FSH secretion in the monkey. In intact adults, the mean (± se) serum concentration of inhibin B was 1008 ± 184 pg/mL. In contrast, circulating inhibin A concentrations were very low (<46 pg/mL). Inhibin B was consistently detected in neonatal monkey serum (275 ± 57 pg/mL), and concentrations of this inhibin dimer increased throughout postnatal development, reaching maximum values in adulthood. Circulating inhibin A concentrations in neonatal and juvenile monkeys were undetectable (<7 pg/mL). Both forms of inhibin were generally undetectable in castrate sera. The ratio of inhibin B concentrations in testicular venous blood to those in the peripheral circulation was 1.4:1. These findings indicate that, in the male monkey, inhibin B is the principal form of circulating dimeric inhibin, and that this hormone is derived exclusively from the testis. The elevated levels of circulating inhibin B in the juvenile male monkey suggest that, during this phase of development, testicular inhibin B secretion is relatively gonadotropin independent. Additionally, we found that the concentration of circulating inhibin A in castrate animals that had earlier received an iv infusion of rh-inhibin A (832 ng/h/kg BW) was 9881 ± 2135 pg/mL, indicating that this mode of inhibin replacement may not have been entirely physiological.

scholarly journals Salmonella Osteomyelitis in a Rhesus Monkey

1986 ◽  
Vol 23 (2) ◽  
pp. 190-197 ◽  
Author(s):  
S. A. Klumpp ◽  
D. S. Weaver ◽  
C. P. Jerome ◽  
M. P. Jokinen
Keyword(s):  
Rhesus Monkey ◽  
Polychlorinated Biphenyl ◽  
Clinical Signs ◽  
Pathologic Fracture ◽  
Left Femur ◽  
Macaca Mulatto ◽  
Severity Of The Disease ◽  
The Right ◽  
Male Rhesus ◽  
Salmonella Osteomyelitis

An adult male rhesus monkey ( Macaca mulatto) developed clinical signs of severe osteomyelitis of the left femur 42 days after onset of enteritis. Salmonella sp. were cultured from feces, blood, and femoral lesions. Response to antibiotic therapy was poor, and the animal was euthanized. The left femur, with pathologic fracture and involucrum, and the right femur, tibia and fibula were most severely affected. Additionally hepatic microgranulomas, mild tubulointcrstitial nephritis, medullary histiocytosis and erythrophagocytosisin the lymph nodes, and a mild colitis were diagnosed microscopically. The severity of the disease and serum electrophoresis findings were suggestive of lowered resistance to the organism, possibly due to anemia or polychlorinated biphenyl toxicosis.

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