Pinealectomy in Agonadal Infantile Male Rhesus Monkeys (Macaca mulatto) Does not Interrupt Initiation of the Prepubertal Hiatus in Gonadotropin Secretion*

Endocrinology ◽  
1986 ◽  
Vol 118 (1) ◽  
pp. 227-232 ◽  
Author(s):  
T. M. PLANT ◽  
D. S. ZORUB
Keyword(s):  
Rhesus Monkeys ◽  
Gonadotropin Secretion ◽  
Macaca Mulatto ◽  
Male Rhesus

Testosterone and the Control of Gonadotropin Secretion in the Male Rhesus Monkey (Macaca mulatto)*

Endocrinology ◽  
1978 ◽  
Vol 103 (2) ◽  
pp. 535-541 ◽  
Author(s):  
T. M. PLANT ◽  
D. L. HESS ◽  
J. HOTCHKISS ◽  
E. KNOBIL
Keyword(s):  
Rhesus Monkey ◽  
Gonadotropin Secretion ◽  
Macaca Mulatto ◽  
Male Rhesus

A Comparison of Moment to Moment and Diurnal Changes in Circulating Inhibin and Testosterone Concentrations in Male Rhesus Monkeys (Macaca mulatto)*

Endocrinology ◽  
1991 ◽  
Vol 129 (4) ◽  
pp. 1755-1761 ◽  
Author(s):  
STEPHEN J. WINTERS ◽  
RUDRIAH MEDHAMURTHY ◽  
VERNON L. GAY ◽  
TONY M. PLANT
Keyword(s):  
Rhesus Monkeys ◽  
Diurnal Changes ◽  
Macaca Mulatto ◽  
Male Rhesus

Evaluation of hippocampus in rhesus monkeys after chronic (1-year) inhalation exposure to marijuana: I. Electron microscopy

1990 ◽  
Vol 48 (3) ◽  
pp. 398-399
Author(s):  
A.M. Andrews ◽  
S.W. Wilson ◽  
A.C. Scallet ◽  
S.F. Ali ◽  
J. Bailey ◽  
...  
Keyword(s):  
Synaptic Vesicles ◽  
Rhesus Monkeys ◽  
Low Dose ◽  
Inhalation Exposure ◽  
Synaptic Cleft ◽  
High Dose ◽  
Withdrawal Time ◽  
Treatment Groups ◽  
Ultrastructural Evidence ◽  
Male Rhesus

Exposure of rhesus monkeys (Macaca mulatta) to marijuana via inhalation or to intravenous delta-9-tetrahydrocannabinol (THC), reportedly caused ultrastructural evidence of increased synaptic width. Chronic marijuana smoke in a single rhesus monkey examined after a six month withdrawal time caused ultrastructure changes in the septal, hippocampal and amygdala regions; the synaptic cleft was widened, electron opaque material was found in the cleft and in the pre- and postsynaptic regions, with some clumping of the synaptic vesicles. The objective of our study was to assess neuropathological alterations produced by chronic inhalation of marijuana smoke.Nineteen male rhesus monkeys, 3-5 years of age and weighing 3-8 kg, were divided into four treatment groups: a) sham control, b) placebo smoke (7 days/ week) c) low dose marijuana (2 times/week with 5 days/week sham) and d) high dose marijuana (7 times/week). A smoke exposure consisted of smoke from one cigarette (2.6% THC) burned down to 10 mm butt length. Smoke was administered via smoke generator (ADL II, Arthur D. Little, Inc. Cambridge, MA) and nose-mouth only masks (local production) equipped with one-way valves.

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