scholarly journals Application of principal component analysis to the study of quantitative structure-activity relationships by means of multiple regression analysis.

1985 ◽  
Vol 33 (4) ◽  
pp. 1488-1495 ◽  
Author(s):  
TANEKAZU KUBOTA ◽  
JIRO HANAMURA ◽  
KENJI KANO ◽  
BUNJI UNO
Keyword(s):  
Principal Component Analysis ◽  
Regression Analysis ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Principal Component ◽  
Component Analysis ◽  
Quantitative Structure ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Quantitative Structure Activity Relationships

scholarly journals STRATEGI BUDIDAYA IKAN KOKI BASTER (Carasius Auratus) RAMAH LINGKUNGAN DALAM UPAYAMENINGKATAN PRODUKSI

2018 ◽  
Vol 19 (2) ◽  
pp. 126-137
Author(s):  
Susanti Mariam ◽  
Eddy Supriyono ◽  
Lina Warlina
Keyword(s):  
Principal Component Analysis ◽  
Regression Analysis ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Organic Fertilizer ◽  
Environmentally Friendly ◽  
Principal Component ◽  
Female Parent ◽  
Component Analysis ◽  
Water Height

Koki baster fish (Carasius auratus) or goldfish, besides as ornamental fish are also used as fish feed and fishing bait which demand tends to increase from year to year. However, from 2012 to 2015, the production of koki baster fish has decreased. This study aims to analyze the application of the management of koki baster fish in Cisaat Subdistrict, Sukabumi Regency, so that a management strategy can be formulated in developing environmentally friendly koki baster in Sukabumi Regency. Data collection was conducted through interviews, observations, questionnaires and documentation. The questionnaires were distributed to 100 respondents who were conducting hatchery for koki baster that scattered in 13 villages in Cisaat Subdistrict. As comparative data, the hatchery of koki baster fish was conducted in the research pond. The variables used are the aquaculture stage (x) consisting of lime dosage, organic fertilizer, anorganic fertilizer, water height, female parent, parent feed, comparison of male and female parent, parent age, larvae feed and duration to number of larvae (y). The variables were analyzed by validity, reliability, multiple regression analysis and principal component analysis using SPSS and Minitab application. Based on the results of multiple regression analysis obtained the relationship between variables in the seeding stage with the number of larvae. Correlation test showed that the variable use of fertilizers had a positive correlation of 69,5% to the number of larvae. Conversely, the variable water height has a negative value on the number of larvae, which is -3.5%. The principal component analysis showed that the variable use of organic fertilizer, anorganic fertilizer and larvae feed was in the first component area. It means that the variable has a large correlation to the number of larvae. The conclusion of there search is the community does not yet have standard in managing fish hatching of koki baster fish, they only rely on experience and habits so that the obtained production is still low. Strategies to increase the production of koki baster fish are need to be standardized on how to farm koki baster fish, standarized koki baster fish and community coaching on the need to carry out the stages of koki baster fish breeding in accordance with the good and environmentally friendly method of fish hatchery.   Ikan koki baster (Carasius auratus) selain sebagai ikan hias juga digunakan sebagai pakan ikan dan umpan pancing yang permintaannnya cenderung meningkat dari tahun ke tahun. Namun demikian dari tahun 2012 hingga 2015, produksi ikan baster mengalami penurunan. Penelitian ini bertujuan menganalisa penerapan manajemen usaha budidaya ikan koki baster di Kecamatan Cisaat Kabupaten Sukabumi sehingga dapat dirumuskan strategi pengelolaan dalam pengembangan budidaya ikan koki baster di Kabupaten Sukabumi yang ramah lingkungan. Pengumpulan data dilakukan melalui wawancara, pengamatan, kuesioner dan dokumentasi. Instrumen yang digunakan adalah kuesioner yang dibagikan kepada 100 orang responden yang melakukan kegiatan pembenihan ikan koki baster di 13 desa yang tersebar di Kecamatan Cisaat. Sebagai data pembanding dilakukan kegiatan pembenihan ikan koki baster di kolam penelitian. Variabel yang digunakan dalam analisis keterkaitan produksi adalah tahapan budidaya (x) yang terdiri atas dosis kapur, pupuk organik, pupuk anorganik, tinggi air, induk betina, pakan induk, perbandingan induk jantan dan betina, umur induk, pakan larva, dan lama pemeliharaan terhadap jumlah larva (y). Variabel-variabel tersebut dianalisis dengan regresi berganda dan analisa komponen utama menggunakan aplikasi SPSS dan Minitab yang sebelumnya dilakukan uji validitas dan reliabilitas.  Berdasarkan hasil analisa regresi berganda diperoleh keterkaitan antara varibael-variabel dalam tahapan pembenihan dengan jumlah larva. Uji korelasi menunjukan variabel penggunaan pupuk berkorelasi positif sebesar 69,5% terhadap jumlah larva.  Sebaliknya variabel tinggi air memiliki nilai korelasi negatif terhadap jumlah larva yaitu sebesar -3,5%.  Analisa komponen utama menunjukan bahwa variabel penggunaan pupuk organik, pupuk anorganik dan pakan larva  berada pada wilayah first component artinya variabel tersebut memiliki korelasi yang besar terhadap jumlah larva. Kesimpulan dari penelitian ini adalah masyarakat belum memiliki standar dalam melaksanakan pengelolaan pembenihan ikan koki baster, hanya mengandalkan pengalaman dan kebiasaan saja sehingga produksi yang diperoleh masih rendah. Strategi untuk meningkatkan produksi ikan koki baster di masyarakat, perlu adanya standar tentang cara budidaya ikan koki baster, standardisasi ikan koki baster dan pembinaan kepada masyarakat tentang perlunya melaksanakan tahapan-tahapan budidaya ikan koki baster sesuai dengan cara pembenihan ikan yang baik dan ramah lingkungan.

scholarly journals ANALISIS PENYIMPANGAN PENGGUNAAN LAHAN BERDASARKAN RENCANA TATA RUANG WILAYAH KABUPATEN SUMEDANG

2018 ◽  
Vol 20 (4) ◽  
pp. 399
Author(s):  
Reny Khaerani ◽  
Santun R.P. Sitorus ◽  
Omo Rusdiana
Keyword(s):  
Principal Component Analysis ◽  
Land Use ◽  
Regression Analysis ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Human Resource ◽  
Spatial Planning ◽  
Rapid Development ◽  
Principal Component ◽  
Spatial Plan

Spatial plan is the result of spatial planning which is done through the process and procedure of arranging and determining based on the prevailing laws and regulations. The phenomenon that often happens is the deviation of existing land use with spatial plan. Sumedang Regency is experiencing a fairly rapid development, so there is an increase in human resource activity that implicate the widespread space needs and consequently deviation of land use is very vulnerable. The purpose of this study to determine the extent of deviation of land use occurs as well as what factors affect the occurence of irregular use of land. The analysis used in this study using GIS approach, Principal Component Analysis and Multiple Regression Analysis. The result of analysis shows that there are 25 types of deviation of existing land use and the most dominant is deviation into wetland (18,364 ha), dryland field (8,405 ha) and widened land (7,741 ha). While the factors that influence the occurence of deviation of land use are population and settlement, availability of land, infrastructure and accessibility, and sosioeconomic condition of society

Activity Evaluation and Selection of Some Classes of Antibiotics with the use of Semi-Empirical Quantum Mechanics and Quantitative Structure- Activity Relationships Approach

2019 ◽  
Vol 22 (2) ◽  
pp. 97-112
Author(s):  
Piotr Kawczak ◽  
Leszek Bober ◽  
Tomasz Bączek
Keyword(s):  
Quantum Mechanics ◽  
Principal Component ◽  
Quantitative Structure ◽  
Activity Data ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Empirical Level ◽  
Quantitative Structure Activity Relationships ◽  
Semi Empirical ◽  
Electronic Elements

Background: A set of β-lactam antibiotics, aminoglycoside antibiotics, and tetracycline antibiotics were proposed and analyzed with the use of Quantitative Structure-Activity Relationships (QSAR) method. Objective: The characterization of selected antimicrobial compounds in terms of both physicochemical and pharmacological on the basis of calculations of quantum mechanics and possessed biological activity data. Methods: During the study, Multiple Linear Regression (MLR) supported with Factor Analysis (FA) and Principal Component Analysis (PCA) was made, as the types of proposed chemometric approach; the semi-empirical level of in silico molecular modeling was used for calculations and comparison of molecular descriptors both in a vacuum and in the aquatic environment. Results: The relationships between structure and microbiological activity enabled the characterization and description of the analyzed molecules using statistically significant descriptors belonging in most cases to different structural, geometric and electronic elements defining at the same time the properties of the studied three different classes of examined antibiotics. Conclusion: The chemometric methods used revealed the influence of some of the elements of structures examined molecules belonging to main antibiotics classes and responsible for the antimicrobial activity.

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