scholarly journals Studies on .BETA.-lactam antibiotics. XIV Synthesis and biological activity of the (E)-isomer of FK027.

1986 ◽  
Vol 34 (8) ◽  
pp. 3458-3464 ◽  
Author(s):  
KOHJI KAWABATA ◽  
KENJI MIYAI ◽  
HISASHI TAKASUGI ◽  
TAKAO TAKAYA
Keyword(s):  
Biological Activity ◽  
Beta Lactam ◽  
Beta Lactam Antibiotics

scholarly journals Studies on .BETA.-lactam antibiotics. IX. Synthesis and biological activity of a new orally active cephalosporin, cefixime (FK027).

1985 ◽  
Vol 38 (12) ◽  
pp. 1738-1751 ◽  
Author(s):  
HIDEAKI YAMANAKA ◽  
TOSHIYUKI CHIBA ◽  
KOHJI KAWABATA ◽  
HISASHI TAKASUGI ◽  
TAKASHI MASUGI ◽  
...  
Keyword(s):  
Biological Activity ◽  
Beta Lactam ◽  
Beta Lactam Antibiotics ◽  
Orally Active

MONITORING OF BIOLOGICAL ACTIVITY OF BETA-LACTAM ANTIBIOTICS RECEPTOR BLAR-CTD IN THE PROCESSES OF ITS HETEROLOGICAL EXPRESSION, PURIFICATION AND APPLICATION IN ANALYTICAL SYSTEMS

2021 ◽  
Vol 1 (19) ◽  
pp. 246-248
Author(s):  
P.A. Semizhon ◽  
H.P. Scheslenok ◽  
I.V. Harbachova ◽  
I.I. Vashkevich ◽  
O.V. Sviridov
Keyword(s):  
Biological Activity ◽  
High Purity ◽  
Test System ◽  
Biologically Active ◽  
Beta Lactam ◽  
Binding Ability ◽  
Immune Systems ◽  
Test Strips ◽  
Beta Lactam Antibiotics

To develop the technologies of beta-lactam antibiotics bioassays in foods, high purity beta-lactam receptor BlaR-CTD has been obtained and characterized. A test system for the quantitation of the biologically active and immunoreactive receptor in the processes of its heterological expression, isolation and reagent forms preparation was elaborated. The immunochemical properties and antibiotic binding ability of BlaR-CTD were investigated, and the constructions and application procedures of receptor-immune systems for the assay of beta-lactam antibiotics using microplates or chromatographic test-strips were proposed.

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