scholarly journals Biomimetic Oxidation of 2-Methylimidazole Derivative with a Chemical Model System for Cytochrome P-450

2002 ◽  
Vol 50 (8) ◽  
pp. 1137-1140 ◽  
Author(s):  
Hiroyuki Miyachi ◽  
Yoshio Nagatsu
Keyword(s):  
Model System ◽  
Chemical Model ◽  
Biomimetic Oxidation ◽  
Cytochrome P 450

scholarly journals Analysis of a chemical model system leading to chiral symmetry breaking: Implications for the evolution of homochirality

2013 ◽  
Vol 52 (1) ◽  
pp. 268-282 ◽  
Author(s):  
Brandy N. Morneau ◽  
Jaclyn M. Kubala ◽  
Carl Barratt ◽  
Pauline M. Schwartz
Keyword(s):  
Symmetry Breaking ◽  
Chiral Symmetry ◽  
Chiral Symmetry Breaking ◽  
Model System ◽  
Chemical Model

First industrial-scale biomimetic oxidation of hydrocarbon with air over metalloporphyrins as cytochrome P-450 monooxygenase model and its mechanistic studies

2009 ◽  
Vol 13 (12) ◽  
pp. 1250-1254 ◽  
Author(s):  
Can-Cheng Guo ◽  
Xiao-Qin Liu ◽  
Qiang Liu ◽  
Yang Liu ◽  
Ming-Fu Chu ◽  
...  
Keyword(s):  
Cyclohexane Oxidation ◽  
Industrial Scale ◽  
Coupling Mechanism ◽  
Mechanistic Studies ◽  
Biomimetic Oxidation ◽  
Low Concentrations ◽  
Temperature And Pressure ◽  
Chemical Cycle ◽  
Cytochrome P 450 ◽  
Oxidation System

A novel industrial-scale trial for cyclohexane oxidation with air over metalloporphyrins as cytochrome P-450 monooxygenase model was reported. Upon addition of extremely low concentrations (1–5 ppm) of simple cobalt porphyrin to the commercial cyclohexane oxidation system, and decrease of the reaction temperature and pressure about 20 °C and 0.4 MPa respectively, the conversion rate of the cyclohexane oxidation increased from 4.8% to 7.1%, the yield of cyclohexanone raised from 77% to 87%, and a 70,000-ton cyclohexanone equipment set yielded an output of 125,000 tons cyclohexanone. Furthermore, a novel biological-chemical-cycle coupling mechanism was proposed to rationalize the aerobic oxidations of hydrocarbons catalyzed by the metalloporphyrins.

Sign in / Sign up

Export Citation Format

Share Document