scholarly journals Rapid Decrease in Brain Enkephalin Content after Low-dose Whole-body X-Irradiation of the Rat.

1992 ◽  
Vol 33 (1) ◽  
pp. 11-15 ◽  
Author(s):  
YUKIHISA MIYACHI ◽  
NORIO OGAWA ◽  
AKITANE MORI
Keyword(s):  
Low Dose ◽  
Rapid Decrease ◽  
Whole Body ◽  
X Irradiation

LATE EFFECTS OF LOW-DOSE WHOLE BODY X-IRRADIATION OF FOUR-DAY-OLD RATS

PEDIATRICS ◽  
1966 ◽  
Vol 38 (6) ◽  
pp. 1047-1056
Author(s):  
Marta S. Billings ◽  
James N. Yamazaki ◽  
Leslie R. Bennett ◽  
Baldwin G. Lamson
Keyword(s):  
Life Span ◽  
Low Dose ◽  
Female Rats ◽  
Whole Body ◽  
Sprague Dawley ◽  
Weight Changes ◽  
F1 Hybrid ◽  
Male And Female ◽  
X Irradiation ◽  
Total Body

1. Four-day-old male and female Long-Evans x Sprague-Dawley F1 hybrid rats were exposed to a single total body x-ray dose of 125, 25, 5, and 0 r and then were observed during their entire lifespan for weight changes, signs of morbidity and age at death. 2. There was a 10% reduction of life span in the 125 r exposed female rats. None of the male groups showed significant shortening of longevity. 3. Mean body weights were consistently lower in both male and female groups exposed to 125 r total body irradiation. 4. Female rats exposed to 25 and 125 r attained their maximum weights at a younger age than their non-irradiated controls. 5. External tumors appeared earlier in female rats. Tumor incidence was not increased by irradiation in either sex. 6. Male parentage influenced the length of life span of progeny to a greater degree than the irradiation exposure at the employed dose-level. The influence of female parentage upon longevity cannot be evaluated in this study. 7. Low dose radiation life shortening can only be demonstrated in long-lived strains. Hereditary and radiation life shortening effects are not cumulative under conditions of this study.

scholarly journals A Single Whole-Body Low Dose X-Irradiation Does Not Affect L1, B1 and IAP Repeat Element DNA Methylation Longitudinally

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e93016 ◽  
Author(s):  
Michelle R. Newman ◽  
Pamela J. Sykes ◽  
Benjamin J. Blyth ◽  
Eva Bezak ◽  
Mark D. Lawrence ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Low Dose ◽  
Repeat Element ◽  
Whole Body ◽  
X Irradiation

scholarly journals Statistical modeling of ultrastructural features of murine dermal collagen under chronic low-dose whole body X-irradiation

FEBS Letters ◽  
2007 ◽  
Vol 581 (26) ◽  
pp. 5034-5042 ◽  
Author(s):  
Jyotirmoy Chatterjee ◽  
Anirban Mukherjee ◽  
Kanchan Mukherjee ◽  
Pranab K. Dutta ◽  
Keya Chaudhuri
Keyword(s):  
Statistical Modeling ◽  
Low Dose ◽  
Whole Body ◽  
Dermal Collagen ◽  
X Irradiation

The Response of Testis Cells to Low Dose X-Irradiation

1981 ◽  
Vol 39 ◽  
pp. 542-543
Author(s):  
D. E. Philpott ◽  
W. Sapp ◽  
C. Williams ◽  
Joann Stevenson ◽  
S. Black
Keyword(s):  
Electron Microscopy ◽  
Stem Cell ◽  
Light Microscopy ◽  
Dose Level ◽  
Cross Sections ◽  
Low Dose ◽  
Light And Electron Microscopy ◽  
Cellular Responses ◽  
Post Irradiation ◽  
X Irradiation

The response of spermatogonial cells to X-irradiation is well documented. It has been shown that there is a radiation resistent stem cell (As) which, after irradiation, replenishes the seminiferous epithelium. Most investigations in this area have dealt with radiation dosages of 100R or more. This study was undertaken to observe cellular responses at doses less than 100R of X-irradiation utilizing a system in which the tissue can be used for light and electron microscopy.Brown B6D2F1 mice aged 16 weeks were exposed to X-irradiation (225KeV; 15mA; filter 0.35 Cu; 50-60 R/min). Four mice were irradiated at each dose level between 1 and 100 rads. Testes were removed 3 days post-irradiation, fixed, and embedded. Sections were cut at 2 microns for light microscopy. After staining, surviving spermatogonia were identified and counted in tubule cross sections. The surviving fraction of spermatogonia compared to control, S/S0, was plotted against dose to give the curve shown in Fig. 1.

scholarly journals Whole Body Low Dose Computed Tomography Using Third-Generation Dual-Source Multidetector With Spectral Shaping: Protocol Optimization and Literature Review

Dose-Response ◽  
2020 ◽  
Vol 18 (4) ◽  
pp. 155932582097313
Author(s):  
Dario Baldi ◽  
Liberatore Tramontano ◽  
Vincenzo Alfano ◽  
Bruna Punzo ◽  
Carlo Cavaliere ◽  
...  
Keyword(s):  
Effective Dose ◽  
Low Dose ◽  
Whole Body ◽  
Dose Length Product ◽  
Osteolytic Lesions ◽  
Subjective Image Quality ◽  
Ct Dose ◽  
Dual Source ◽  
Ct Dose Index ◽  
Low Dose Computed Tomography

For decades, the main imaging tool for multiple myeloma (MM) patient’s management has been the conventional skeleton survey. In 2014 international myeloma working group defined the advantages of the whole-body low dose computed tomography (WBLDCT) as a gold standard, among imaging modalities, for bone disease assessment and subsequently implemented this technique in the MM diagnostic workflow. The aim of this study is to investigate, in a group of 30 patients with a new diagnosis of MM, the radiation dose (CT dose index, dose-length product, effective dose), the subjective image quality score and osseous/extra-osseous findings rate with a modified WBLDCT protocol. Spectral shaping and third-generation dual-source multidetector CT scanner was used for the assessment of osteolytic lesions due to MM, and the dose exposure was compared with the literature findings reported until 2020. Mean radiation dose parameters were reported as follows: CT dose index 0.3 ± 0.1 mGy, Dose-Length Product 52.0 ± 22.5 mGy*cm, effective dose 0.44 ± 0.19 mSv. Subjective image quality was good/excellent in all subjects. 11/30 patients showed osteolytic lesions, with a percentage of extra-osseous findings detected in 9/30 patients. Our data confirmed the advantages of WBLDCT in the diagnosis of patients with MM, reporting an effective dose for our protocol as the lowest among previous literature findings.

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