scholarly journals In Vivo Measurement of Brain GABA Concentrations by Magnetic Resonance Spectroscopy in Smelters Occupationally Exposed to Manganese

2011 ◽  
Vol 119 (2) ◽  
pp. 219-224 ◽  
Author(s):  
Ulrike Dydak ◽  
Yue-Ming Jiang ◽  
Li-Ling Long ◽  
He Zhu ◽  
Jian Chen ◽  
...  
2009 ◽  
Vol 62 (2) ◽  
pp. 307-313 ◽  
Author(s):  
Daniel M. Spielman ◽  
Dirk Mayer ◽  
Yi-Fen Yen ◽  
James Tropp ◽  
Ralph E. Hurd ◽  
...  

1995 ◽  
Vol 37 (2) ◽  
pp. 244-249 ◽  
Author(s):  
Edward J Novotny ◽  
Malcolm J Avison ◽  
Norbert Herschkowitz ◽  
Ognen A C Petroff ◽  
James W Prichard ◽  
...  

2020 ◽  
Author(s):  
Li An ◽  
Shizhe Li ◽  
Maria Ferraris Araneta ◽  
Milalynn Victorino ◽  
Christopher Johnson ◽  
...  

Abstract A single-step spectral editing 1H magnetic resonance spectroscopy (MRS) technique was used to measure fractional enrichments of glutamate and glutamine in the dorsal anterior cingulate cortex of five healthy volunteers after oral administration of [U-13C]glucose. Strong pseudo singlets of glutamate and glutamine were induced at an echo time of 56 ms using an always-on editing pulse at 2.12 ppm. At 113 ± 9 minutes after oral administration of [U-13C]glucose, fractional enrichment of glutamate was found to be 64 ± 5% with 1.7% within-subject coefficient of variation (CV) and fractional enrichment of glutamine was found to be 40 ± 10% with 11% within-subject CV. This study demonstrated that 13C labeling of both glutamate and glutamine can be measured with the high sensitivity and spatial resolution of proton MRS using a proton-only MRS technique with standard commercial hardware. Furthermore, it is now feasible to measure 13C labeling of glutamate and glutamine in limbic structures, which play major roles in behavioral and emotional responses and whose abnormalities are involved in many neuropsychiatric disorders.


NeuroImage ◽  
2021 ◽  
pp. 118215
Author(s):  
Sudeepta K. Basu ◽  
Subechhya Pradhan ◽  
Adre J. du Plessis ◽  
Yehezkel Ben-Ari ◽  
Catherine Limperopoulos

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