scholarly journals Resistance of Cotton Rats, Sigmodon hispidus, to Primary Infection by Nippostrongylus brasiliensis

2002 ◽  
Vol 64 (5) ◽  
pp. 423-426 ◽  
Author(s):  
Hendra WIBAWA ◽  
Deni NOVIANA ◽  
Kimiyuki TSUCHIYA ◽  
Fadjar SATRIJA ◽  
Yoichiro HORII
Keyword(s):  
Primary Infection ◽  
Nippostrongylus Brasiliensis ◽  
Sigmodon Hispidus ◽  
Cotton Rats

Cotton rats ( Sigmodon hispidus ) with a high prevalence of hydrocephalus without clinical symptoms

2021 ◽  
Author(s):  
Daisuke Kondoh ◽  
Teppei Nakamura ◽  
Erika Tsuji ◽  
Marina Hosotani ◽  
Osamu Ichii ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Sigmodon Hispidus ◽  
High Prevalence ◽  
Cotton Rats

Sensitivity of Wild Cotton Rats ( Sigmodon hispidus ) to the Immunotoxic Effects of Low-Level Arsenic Exposure

1998 ◽  
Vol 34 (3) ◽  
pp. 289-296 ◽  
Author(s):  
M. Savabieasfahani ◽  
R. L. Lochmiller ◽  
D. P. Rafferty ◽  
J. A. Sinclair
Keyword(s):  
Arsenic Exposure ◽  
Sigmodon Hispidus ◽  
Low Level ◽  
Wild Cotton ◽  
Cotton Rats

Activity patterns in relation to body mass and ambient temperature among overwintering cotton rats (Sigmodon hispidus)

1998 ◽  
Vol 76 (4) ◽  
pp. 668-672 ◽  
Author(s):  
Maria A Eifler ◽  
Norman A Slade
Keyword(s):  
Specific Activity ◽  
Activity Patterns ◽  
General Linear Model ◽  
Time Of Day ◽  
Sigmodon Hispidus ◽  
Activity Levels ◽  
Class Time ◽  
Time Class ◽  
Cotton Rats ◽  
Probability Of Capture

We examined mass-specific activity patterns among overwintering cotton rats (Sigmodon hispidus) in northeastern Kansas. We livetrapped animals for a 24-h period, checking traps every 2 h. Trapping occurred every 2 weeks for 5 months. We estimated probability of capture for each mass class, time class, and date, then tested for differences in probability of capture (i.e., activity levels) using a General Linear Model with temperature as a covariate. Large cotton rats were significantly less active than small and intermediate-sized cotton rats. Activity of small cotton rats increased with decreasing temperature, whereas larger cotton rats were less responsive to temperature. Finally, activity levels of large and small cotton rats did not vary significantly with time of day, but intermediate-sized cotton rats were significantly less likely to be captured during the night than at dusk.

Passive narcosis for anesthesia induction in cotton rats (Sigmodon hispidus)

Lab Animal ◽  
2016 ◽  
Vol 45 (9) ◽  
pp. 333-337
Author(s):  
Jarod M. Hanson ◽  
Lydia J. Anderson ◽  
Colin M. Williams ◽  
Patricia Jorquera ◽  
Ralph A. Tripp
Keyword(s):  
Anesthesia Induction ◽  
Sigmodon Hispidus ◽  
Cotton Rats

Female cotton rats (Sigmodon hispidus) develop chronic anemia with renal inflammation and cystic changes

2016 ◽  
Vol 146 (3) ◽  
pp. 351-362 ◽  
Author(s):  
Osamu Ichii ◽  
Teppei Nakamura ◽  
Takao Irie ◽  
Hirokazu Kouguchi ◽  
Daisuke Nakamura ◽  
...  
Keyword(s):  
Sigmodon Hispidus ◽  
Chronic Anemia ◽  
Renal Inflammation ◽  
Cystic Changes ◽  
Cotton Rats

Physiological responses of rats to primary infection with Nippostrongylus brasiliensis

1986 ◽  
Vol 60 (4) ◽  
pp. 307-312 ◽  
Author(s):  
K. S. Ovington
Keyword(s):  
Food Intake ◽  
Primary Infection ◽  
Physiological Responses ◽  
Host Responses ◽  
Nippostrongylus Brasiliensis ◽  
Intestinal Nematode ◽  
Microbial Infections ◽  
Rate Of Oxygen Consumption ◽  
Muscle Catabolism ◽  
Ad Libitum

ABSTRACTThe physiological responses of well-nourished rats to primary infection with the intestinal nematode Nippostrongylus brasiliensis were examined. Infected rats fed ad libitum were compared with uninfected control rats fed ad lib. and also with uninfected rats which were pair-fed to the infected rats. Following infection with N. brasiliensis rat food intake was reduced from day 2 post infection (pi) and there were two periods of minimal food intake (day 2 to 3 and 8 to 9 pi). The water intake of infected rats was only reduced on days 2, 3 and 9 pi and not to the same extent as food intake. Muscle catabolism in infected rats was more severe than could be explained on the basis of their food intake reduction. The rectal temperature and rate of oxygen consumption per g body-weight of rats was not significantly altered by the infection. Host responses to N. brasiliensis are compared with those seen in microbial infections and some of them are found to be considerably different.

Fluctuations in rat liver alanine-amino-transferase activity during experimental nippostrongylosis

Parasitology ◽  
1989 ◽  
Vol 98 (2) ◽  
pp. 301-306
Author(s):  
Lucy J. Robertson
Keyword(s):  
Immune Response ◽  
Primary Infection ◽  
Parasitic Infection ◽  
Transferase Activity ◽  
Nippostrongylus Brasiliensis ◽  
Alanine Amino Transferase ◽  
A Value ◽  
Gluconeogenic Enzyme ◽  
Alt Activity

SUMMARYThe activity of the gluconeogenic enzyme, alanine-amino-transferase (ALT), in a preparation from the liver of rats was studied by means of an in vitro assay throughout the course of a primary infection of Nippostrongylus brasiliensis, established by a subcutaneous injection of approximately 4000 3rd-stage larvae. The activity was measured on days 1–14 p.i. in both uninfected and infected rats and a marked pattern in the enzyme's activity was observed. In infected rats, the activity increased from 1·46±0·19 U/g liver on day 1 p.i. to a peak on day 4 p.i. of 10·75±1·62 U/g liver, then decreased to a trough of 0·44±0·18 U/g liver on day 10 p.i. before returning to original levels by day 14 p.i., by which time the infection had been largely eliminated. In uninfected rats the activity of the liver enzyme remained constant throughout this period with a value of 2·54±0·12 U/g liver. The activity of the enzyme in vitro was found to be related to the size of the inoculum on days 4 and 10 p.i. It was proposed that these observations could be due to either (1) a direct effect of the parasite, or (2) a consequence of the host immune response to the infection. In order to investigate the second proposition more fully, liver ALT activity was investigated by in vitro assay on selected days p.i. in rats experiencing a secondary N. brasiliensis infection. In these rats the liver ALT activity was observed to reach a peak on day 2 p.i., with an activity of 3·87 ± 0-28 U/g liver, and a trough on day 4 p.i. with an activity of 0·11 ±0·03 U/g liver, returning to similar levels to those measured in uninfected rats by day 7 p.i. When serum prepared from rats having secondary N. brasiliensis infections collected on day 4 p.i. was added to the assay, a reduction in the activity of liver ALT activity from both the infected and uninfected rats was measured by in vitro assay. The results are discussed in relation to protein metabolism and gluconeogenesis in rats infected with N. brasiliensis, and also in relation to the host’s immune response to the parasitic infection.

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