scholarly journals Incidence of contrast-induced acute kidney injury (CI-AKI) in high-risk oncology patients undergoing contrast-enhanced CT with a reduced dose of the iso-osmolar iodinated contrast medium iodixanol

PLoS ONE ◽  
2020 ◽  
Vol 15 (5) ◽  
pp. e0233433
Author(s):  
Sebastian Werner ◽  
Christian Bez ◽  
Clemens Hinterleitner ◽  
Marius Horger
Keyword(s):  
Acute Kidney Injury ◽  
High Risk ◽  
Contrast Medium ◽  
Kidney Injury ◽  
Reduced Dose ◽  
Iodinated Contrast Medium ◽  
Iodinated Contrast ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct

Iso-Osmolality versus Low-Osmolality Iodinated Contrast Medium at Intravenous Contrast-enhanced CT: Effect on Kidney Function

Radiology ◽  
2008 ◽  
Vol 248 (1) ◽  
pp. 97-105 ◽  
Author(s):  
Shaun A. Nguyen ◽  
Pal Suranyi ◽  
James G. Ravenel ◽  
Patrick K. Randall ◽  
Peter B. Romano ◽  
...  
Keyword(s):  
Contrast Medium ◽  
Kidney Function ◽  
Intravenous Contrast ◽  
Iodinated Contrast Medium ◽  
Iodinated Contrast ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct

scholarly journals Intravenous iodinated contrast is not associated with acute kidney injury in adult patients with nephrotic syndrome

2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Andrew Bacyinski
Keyword(s):  
Acute Kidney Injury ◽  
Nephrotic Syndrome ◽  
Retrospective Cohort ◽  
Critical Appraisal ◽  
Kidney Injury ◽  
European Radiology ◽  
Iodinated Contrast ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct

<p>A critical appraisal and clinical application of Tao SM, Kong X, Schoepf UJ, et al. Acute kidney injury in patients with nephrotic syndrome undergoing contrast-enhanced CT for suspected venous thromboembolism: a propensity score-matched retrospective cohort study. <em>European Radiology</em>. 2018;28(4):1585-1593. doi: <a href="https://doi.org/10.1007/s00330-017-5109-0">10.1007/s00330-017-5109-0</a></p>

Risk of acute kidney injury in cancer patients after iodinated contrast medium administration and prophylactic strategies: Summary from the most recent guidelines

2021 ◽  
pp. 239936932110285
Author(s):  
Pirovano Marta ◽  
Minei Silvia ◽  
Re Sartò Giulia Vanessa ◽  
Cosmai Laura
Keyword(s):  
Acute Kidney Injury ◽  
Contrast Medium ◽  
Cancer Patients ◽  
Kidney Injury ◽  
Post Contrast ◽  
Iodinated Contrast Medium ◽  
Iodinated Contrast ◽  
Contrast Enhanced ◽  
Nephrotoxic Drugs ◽  
Enhanced Computed Tomography

Post-contrast acute kidney injury (PC-AKI) is a serious complication that primarily affects people with multiple comorbidities who undergo imaging examination with iodinated contrast medium (CM), worsening their outcome and prognosis. This is particularly true for cancer patients, for whom contrast enhanced computed tomography (CECT) is of considerable value in diagnosis and management of the tumor and who are frequently subjected to dehydration and administration of nephrotoxic drugs. The debate on the real prevalence and severity of acute kidney injury (AKI) due to CM administration is still ongoing and the lack of controlled studies and reliable evidence has generated wide heterogeneity in patient management and prophylaxis. The whole idea of this protocol is to analyze most up-to-date guidelines on preventing AKI due to CM administration trying to provide a practical guide.

scholarly journals Contrast-Induced Acute Kidney Injury: Definition, Epidemiology, and Outcome

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Felix G. Meinel ◽  
Carlo N. De Cecco ◽  
U. Joseph Schoepf ◽  
Richard Katzberg
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Renal Insufficiency ◽  
Time Window ◽  
Contrast Material ◽  
Kidney Injury ◽  
Preventive Strategy ◽  
Iodinated Contrast ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced

Contrast-induced acute kidney injury (CI-AKI) is commonly defined as a decline in kidney function occurring in a narrow time window after administration of iodinated contrast material. The incidence of AKI after contrast material administration greatly depends on the specific definition and cutoff values used. Although self-limiting in most cases, postcontrast AKI carries a risk of more permanent renal insufficiency, dialysis, and death. The risk of AKI from contrast material, in particular when administered intravenously for contrast-enhanced CT, has been exaggerated by older, noncontrolled studies due to background fluctuations in renal function. More recent evidence from controlled studies suggests that the risk is likely nonexistent in patients with normal renal function, but there may be a risk in patients with renal insufficiency. However, even in this patient population, the risk of CI-AKI is probably much smaller than traditionally assumed. Since volume expansion is the only preventive strategy with a convincing evidence base, liberal hydration should be encouraged to further minimize the risk. The benefits of the diagnostic information gained from contrast-enhanced examinations will still need to be balanced with the potential risk of CI-AKI for the individual patient and clinical scenario.

scholarly journals Post-Contrast Acute Kidney Injury in Patients with Various Stages of Chronic Kidney Disease—Is Fear Justified?

Toxins ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 395
Author(s):  
Inga Chomicka ◽  
Marlena Kwiatkowska ◽  
Alicja Lesniak ◽  
Jolanta Malyszko
Keyword(s):  
Computed Tomography ◽  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Kidney Injury ◽  
Creatinine Concentration ◽  
Post Contrast ◽  
Iodinated Contrast ◽  
Contrast Enhanced Ct ◽  
Enhanced Ct

Post-contrast acute kidney injury (PC-AKI) is one of the side effects of iodinated contrast media, including those used in computed tomography. Its incidence seems exaggerated, and thus we decided to try estimate that number and investigate its significance in our clinical practice. We analyzed all computed tomographies performed in our clinic in 2019, including data about the patient and the procedure. In each case, we recorded the parameters of kidney function (serum creatinine concentration and eGFR) in four time intervals: before the test, immediately after the test, 14–28 days after the test, and over 28 days after the test. Patients who did not have a follow-up after computed tomography were excluded. After reviewing 706 CT scans performed in 2019, we included 284 patients undergoing contrast-enhanced CT and 67 non-enhanced CT in the final analysis. On this basis, we created two comparable groups in terms of age, gender, the severity of chronic kidney disease, and the number of comorbidities. We found that AKI was more common in the non-enhanced CT population (25.4% vs. 17.9%). In terms of our experience, it seems that PC-AKI is not a great risk for patients, even those with chronic kidney disease. Consequently, the fear of using contrast agents is not justified.

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