COMPARISON OF RAPID SHALLOW BREATHING INDEX MEASURED ON PRESSURE SUPPORT VENTILATION AND SPONTANEOUS BREATHING TRIAL TO PREDICT WEANING FROM MECHANICAL VENTILATION

CHEST Journal ◽  
2009 ◽  
Vol 136 (4) ◽  
pp. 32S
Author(s):  
Hiren B. Shingala ◽  
Wissam B. Abouzgheib ◽  
Jamil Darrouj ◽  
Melvin R. Pratter
Surgery ◽  
1997 ◽  
Vol 122 (4) ◽  
pp. 737-741 ◽  
Author(s):  
Jay A Johannigman ◽  
Kenneth Davis ◽  
Robert S Campbell ◽  
Richard D Branson ◽  
Fred A Luchette ◽  
...  

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110100
Author(s):  
Ju Gong ◽  
Bibo Zhang ◽  
Xiaowen Huang ◽  
Bin Li ◽  
Jian Huang

Objective Clinicians cannot precisely determine the time for withdrawal of ventilation. We aimed to evaluate the performance of driving pressure (DP)×respiratory rate (RR) to predict the outcome of weaning. Methods Plateau pressure (Pplat) and total positive end-expiratory pressure (PEEPtot) were measured during mechanical ventilation with brief deep sedation and on volume-controlled mechanical ventilation with a tidal volume of 6 mL/kg and a PEEP of 0 cmH2O. Pplat and PEEPtot were measured by patients holding their breath for 2 s after inhalation and exhalation, respectively. DP was determined as Pplat minus PEEPtot. The rapid shallow breathing index was measured from the ventilator. The highest RR was recorded within 3 minutes during a spontaneous breathing trial. Patients who tolerated a spontaneous breathing trial for 1 hour were extubated. Results Among the 105 patients studied, 44 failed weaning. During ventilation withdrawal, DP×RR was 136.7±35.2 cmH2O breaths/minute in the success group and 230.2±52.2 cmH2O breaths/minute in the failure group. A DP×RR index >170.8 cmH2O breaths/minute had a sensitivity of 93.2% and specificity of 88.5% to predict failure of weaning. Conclusions Measurement of DP×RR during withdrawal of ventilation may help predict the weaning outcome. A high DP×RR increases the likelihood of weaning failure. Statement: This manuscript was previously posted as a preprint on Research Square with the following link: https://www.researchsquare.com/article/rs-15065/v3 and DOI: 10.21203/rs.2.24506/v3


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