scholarly journals Current methods of the modeling of experimental diabetes mellitus type 2: a literature review

Pathologia ◽  
2016 ◽  
Vol 0 (1) ◽  
Author(s):  
Yu. M. Kolesnyk ◽  
T. V. Ivanenko ◽  
A. V. Abramov ◽  
N. V. Kuzo
Keyword(s):  
Diabetes Mellitus ◽  
Literature Review ◽  
Diabetes Mellitus Type 2 ◽  
Experimental Diabetes ◽  
Diabetes Mellitus Type ◽  
Experimental Diabetes Mellitus

scholarly journals ASSOCIATION OF DIABETES MELLITUS TYPE 2 AND ANTIDIABETIC DRUGS WITH PANCREATIC CARCINOMA: A LITERATURE REVIEW

2021 ◽  
Vol 58 ◽  
pp. eUJ3944-eUJ3944
Author(s):  
Larissa Emilly Fiusa do Monte ◽  
◽  
Juliana Ramos Carneiro ◽  
Antonio Camilo Correia Mendes Filho ◽  
Leonardo Silva dos Santos ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Literature Review ◽  
Pancreatic Carcinoma ◽  
Diabetes Mellitus Type 2 ◽  
Antidiabetic Drugs ◽  
Diabetes Mellitus Type

O câncer de pâncreas possui alta taxa de mortalidade e, com frequência, seu diagnóstico tem sido associado ao de diabetes mellitus tipo 2 (DMT2), embora os mecanismos fisiopatológicos dessa relação ainda necessitem de esclarecimentos. Dessa forma, o objetivo deste estudo é analisar os aspectos da associação entre a DMT2 e sua terapia farmacológica com o desenvolvimento de carcinoma pancreático. Para este fim, realizou-se uma busca criteriosa da literatura publicada entre 2015 e 2020 em bases de dados eletrônicas em saúde, e, após o processo de seleção, 13 artigos na BVS e 14 na PUBMED foram incluídos neste estudo. Em suma, a característica inflamatória da DMT2, a hiperinsulinemia e a resistência à insulina são hipóteses fisiopatológicas da associação. Outrossim, é significativa a relação da diabetes de longa duração com o desenvolvimento do carcinoma, apesar de a diabetes de início recente também demonstrar-se relevante. Ademais, a associação entre medicamentos antidiabéticos e câncer de pâncreas também é avaliada. Sob esse viés, alguns medicamentos, como a metformina, estão associados a efeitos antitumorais. Em contrapartida, as incretinas estão relacionadas à carcinogênese, devido aos seus potenciais efeitos deletérios no pâncreas. Em paralelo, a insulina pode amplificar a relação entre hiperinsulinemia e o risco de malignidade, assim como drogas como as sulfonilureias, que estão associadas ao risco aumentado de câncer por provocar estimulação anormal da proliferação celular.

scholarly journals EVALUASI HUBUNGAN DUKUNGAN KELUARGA DAN KUALITAS HIDUP PENDERITA DIABETES MELITUS TIPE 2 : LITERATUR REVIEW

2020 ◽  
Vol 8 (2) ◽  
pp. 44
Author(s):  
Rensi R. Runtuwarow ◽  
Mario E. Katuuk ◽  
Reginus T. Malara
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Literature Review ◽  
Family Support ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Diabetes Melitus

Abstract: Diabetes mellitus (DM) is a serious public health problem. Where this disease is one of the highest diseases of the four non-communicable diseases. In this DM disease if not treated properly will produce in complications with serious illness. Objective. The purpose of this study was to evaluate the relationship between family support and the quality of life of people with type 2 diabetes mellitus. The method. Used literature review to compile this literature review was to search through an electronic database. The article search was carried out using the keywords Family Support, Quality Of Life, Diabetes mellitus type 2, which was traced through Google Scholar and Pubmed. 945 articles were identified and published from 2015-20120. Out of 945 articles, only  4 articles met the requirements to be analyzed. Results. Based on the articles that have been reviewed show that family support is very important in overcoming the quality of life of people with type 2 diabetes and one in four articles found no results and three of the four articles information. Conclusion. Literature review evaluation results can be concluded from two major themes namely family support and quality of life having their respective categories obtained according to the analysis that researchers conducted. 90% of the results of these four articles show a relationship between family support and the quality of life of people with type 2 diabetes. Keywords: Family Support, Quality of Life, Diabetes Mellitus Type 2. AbstrakDiabetes Melitus (DM) merupakan masalah kesehatan masyarakat yang serius. Dimana penyakit ini menjadi salah satu penyakit tertinggi dari empat penyakit tidak menular. Pada penyakit DM ini apabila tidak ditangani dengan baik akan mengakibatkan timbulnya komplikasi dengan penyakit yang serius. Tujuan Penelitian untuk mengevaluasi hubungan dukungan keluarga dan kualitas hidup penderita diabetes mellitus tipe 2. Metode literature review, yang digunakan untuk menyusun tinjauan pustaka ini adalah dengan mencari melalui database elektronik. Pencarian artikel dilakukan dengan menggunakan kata kunci Family Support, Quality Of Life, Diabetes mellitus type 2 yang ditelusuri melalui Google Scholar dan Pubmed. Didapatkan 945 artikel yang diidentifikasi dan dipublikasikan dari tahun 2015-20120. Dari 945 artikel hanya 4 artikel yang memeuhi syarat untuk dianalisis. Hasil berdasarkan artikel-artikel yang telah ditinjau menunjukan bahwa dukungan keluarga sangat berperan penting dalam mengatasi kualitas hidup dari penderita DM tipe 2 dan satu dari empat artikel menemukan hasil tidak ada buhungan dan tiga dari keempat artikel memberikan hasil adanya hubungan. Kesimpulan hasil evaluasi tinjauan pustaka dapatdisimpulkan dari dua tema besar yaitu dukungan keluarga dan kualitas hidup memiliki kategorinya masing-masing yang diperoleh menurut analisis yang peneliti lakukan. 90% hasil dari keempat artikel ini menunjukan adanya hubungan dukungan keluarga dan kualitas hidup penderita DM tipe 2.Kata Kunci: Dukungan Keluarga, Kualitas Hidup, Diabetes Melitus Tipe 2

Sign in / Sign up

Export Citation Format

Share Document