8 Paramagnetic Metal Ion Probes for 19F Magnetic Resonance Imaging

2021 ◽  
pp. 239-270
Author(s):  
Petr Hermann ◽  
Jan Blahut ◽  
Jan Kotek ◽  
Vít Herynek
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Metal Ion ◽  
Resonance Imaging ◽  
Paramagnetic Metal ◽  
19F Magnetic Resonance Imaging

scholarly journals Monitoring Transport Phenomena of Paramagnetic Metal-Ion Complexes Inside Catalyst Bodies with Magnetic Resonance Imaging

2008 ◽  
Vol 14 (8) ◽  
pp. 2363-2374 ◽  
Author(s):  
Jaap A. Bergwerff ◽  
Anna A. Lysova ◽  
Leticia Espinosa-Alonso ◽  
Igor V. Koptyug ◽  
Bert M. Weckhuysen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Metal Ion ◽  
Transport Phenomena ◽  
Resonance Imaging ◽  
Metal Ion Complexes ◽  
Paramagnetic Metal

scholarly journals Metal Ion Sensing Using Ion Chemical Exchange Saturation Transfer 19F Magnetic Resonance Imaging

2013 ◽  
Vol 135 (33) ◽  
pp. 12164-12167 ◽  
Author(s):  
Amnon Bar-Shir ◽  
Assaf A. Gilad ◽  
Kannie W. Y. Chan ◽  
Guanshu Liu ◽  
Peter C. M. van Zijl ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Metal Ion ◽  
Chemical Exchange ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Resonance Imaging ◽  
Ion Sensing ◽  
Metal Ion Sensing ◽  
19F Magnetic Resonance Imaging

Parameter optimization and calibration of 19F magnetic resonance imaging at 1.5 Tesla

1991 ◽  
Vol 9 (1) ◽  
pp. 101-106 ◽  
Author(s):  
Benzhi Gong ◽  
Michael Gill ◽  
David B. Washburn ◽  
W. Clark Davenport ◽  
Dorothy Adams ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Parameter Optimization ◽  
Resonance Imaging ◽  
19F Magnetic Resonance Imaging

Detection of Tumors with 19F Magnetic Resonance Imaging

1988 ◽  
Vol 23 (5) ◽  
pp. 361-364 ◽  
Author(s):  
ADAM V. RATNER ◽  
HOLDE H. MULLER ◽  
BEVERLY BRADLEY-SIMPSON ◽  
DANNA E. JOHNSON ◽  
RALPH E. HURD ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
19F Magnetic Resonance Imaging

scholarly journals Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0163704 ◽  
Author(s):  
Alexander J. Taylor ◽  
Josef Granwehr ◽  
Clémentine Lesbats ◽  
James L. Krupa ◽  
Joseph S. Six ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Detection Limits ◽  
Resonance Imaging ◽  
Specific Procedure ◽  
19F Magnetic Resonance Imaging

scholarly journals Functionalized Gold Nanoparticles as Contrast Agents for Proton and Dual Proton/Fluorine MRI

Nanomaterials ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 879 ◽  
Author(s):  
Maria Şologan ◽  
Francesco Padelli ◽  
Isabella Giachetti ◽  
Domenico Aquino ◽  
Mariangela Boccalon ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Gold Nanoparticles ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
High Sensitivity ◽  
Mri Contrast Agents ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Gold Core ◽  
19F Magnetic Resonance Imaging

Gold nanoparticles carrying fluorinated ligands in their monolayer are, by themselves, contrast agents for 19F magnetic resonance imaging displaying high sensitivity because of the high density of fluorine nuclei achievable by grafting suitable ligands on the gold core surface. Functionalization of these nanoparticles with Gd(III) chelates allows adding a further functional activity to these systems, developing materials also acting as contrast agents for proton magnetic resonance imaging. These dual mode contrast agents may allow capitalizing on the benefits of 1H and 19F magnetic resonance imaging in a single diagnostic session. In this work, we describe a proof of principle of this approach by studying these nanoparticles in a high field preclinical scanner. The Gd(III) centers within the nanoparticles monolayer shorten considerably the 19F T1 of the ligands but, nevertheless, these systems display strong and sharp NMR signals which allow recording good quality 19F MRI phantom images at nanoparticle concentration of 20 mg/mL after proper adjustment of the imaging sequence. The Gd(III) centers also influence the T1 relaxation time of the water protons and high quality 1H MRI images could be obtained. Gold nanoparticles protected by hydrogenated ligands and decorated with Gd(III) chelates are reported for comparison as 1H MRI contrast agents.

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