Physical Activity in Prevention of Risk and Disability in Some Neurological Diseases

2014 ◽  
Vol 22 (1) ◽  
pp. 21-27
Author(s):  
Józef Opara
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Multiple Sclerosis ◽  
Physical Disability ◽  
Neurological Diseases ◽  
Review Of The Literature ◽  
Disability Progression ◽  
Multiple Sclerosis Patients

Abstract The question of the role of physical activity in preventing disability in neurological diseases is the issue which is not in doubt. There is well known that physical activity in Parkinson`s disease and in Multiple Sclerosis patients is less than is the case in the general population. Numerous scientific studies have confirmed the low physical activity of people with PD and MS. Improving physical activity delays the progress of physical disability and has the effect on increasing the quality of life in those two diseases. In this paper an descriptive review of the literature devoted to the effect of physical activity on risk of PD and its impact on disability progression in PD and MS has been presented. The different recommendations for physical activity and different methods of assessment have been described.

scholarly journals 178Depression but not physical activity mediates the fatigue-mental quality of life relationship in multiple sclerosis

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Alexander Fidao ◽  
Alysha De Livera ◽  
Tracey Weiland ◽  
George Jelinek ◽  
Sandra Neate ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Multiple Sclerosis ◽  
Indirect Effect ◽  
Mediation Effect ◽  
Study Cohort ◽  
Wide Range ◽  
Clinically Significant

Abstract Background Fatigue is among the most prevalent symptoms of multiple sclerosis (MS), and significantly detrimental to mental quality of life. We examined the role of depression and physical activity as mediators in the fatigue-QoL relationship in MS. Methods Using an international study cohort measuring a wide range of lifestyle and clinical factors, determinants of fatigue (Fatigue Severity Scale) and mental quality of life (MSQoL-54; QoL) were assessed in 2,104 participants using log-binomial and linear regression, respectively. Structural equation modelling (SEM) was used to assess the mediating role of depression and physical activity between fatigue and mental QoL. Results The median mental QoL score in the sample was 73.8/100. The mean fatigue score was 40.5/63, with 65.6% having clinically significant fatigue. In SEM analyses evaluating depression as a mediator of the fatigue-QoL relationship, mental QoL was 14.17-points lower in those with clinically significant fatigue, of which the indirect effect via depression accounted for over 30.8% (p < 0.001). This mediation effect was most pronounced for the Role Limitations from Emotional Issues (44.9%, p < 0.001) and Emotional Wellbeing (41.6%, p < 0.001) subdomains. Evaluating physical activity as a mediator of the fatigue-QoL relationship, mental QoL was 11.03-points lower in those with clinically significant fatigue, of which the indirect effect via physical activity accounted for only 1.0% (p = 0.001). Conclusions This study provides evidence that depression accounts for a majority of the fatigue-mental QoL relationship, while physical activity only plays a small role. While replication and longitudinal studies are required for validation, our findings may inform the development of treatments for reducing the impacts of fatigue and improving QoL in people with MS. Key messages Fatigue’s negative impact on emotional quality of life in multiple sclerosis is not a function of reduced ambulation but instead its impact on depression. Reducing depression may thus markedly improve quality of life in this population.

Reduced quality of life among multiple sclerosis patients with sexual disturbance and bladder dysfunction

2001 ◽  
Vol 7 (4) ◽  
pp. 231-235 ◽  
Author(s):  
M W Nortvedt ◽  
T Riise ◽  
K-M Myhr ◽  
A-M Landtblom ◽  
A Bakke ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Physical Disability ◽  
Bladder Dysfunction ◽  
Survey Methods ◽  
Normal Population ◽  
Cross Sectional ◽  
Sf 36 ◽  
Multiple Sclerosis Patients

Objective: Physical disability explains only part of the reduced quality of life found among multiple sclerosis (MS) patients. Bladder dysfunction and sexual disturbance are frequent and distressing problems for MS patients. We therefore estimated the relationship between the presence and degree of sexual disturbance/bladder dysfunction and the patients' quality of life as measured by the SF-36 Health Survey. Methods: We performed a cross-sectional study of all individuals with the onset of MS between 1976 and 1986 in Hordaland County, Norway. The disease duration at examination was 9-19 years; 194 patients (94%) participated. Results: Fifty-three per cent of the patients with low physical disability (Expanded Disability Status Scale (EDSS)≤44.0) reported disease-related sexual disturbance and 44% had bladder dysfunction according to the Incapacity Status Scale. The corresponding figures for the patients with a high physical disability (EDSS>44.0) were 86 and 81% respectively. The patients with sexual disturbance had markedly and significantly reduced scores on all eight SF-36 scales, this was after adjustment for disease development measured by the EDSS. The patients without sexual disturbance scored 0.5 s.d. lower than a normal population on the social functioning scale, whereas those with marked sexual disturbance scored 1.5 s.d. lower. Similar results were found for the patients with bladder dysfunction. Conclusion: Bladder and sexual problems are associated with a marked reduction in the quality of life, also among patients with otherwise low disability. This underlines the need for identifying and treating these problems.

scholarly journals The Role of Stress Perception and Coping with Stress and the Quality of Life Among Multiple Sclerosis Patients

2021 ◽  
Vol Volume 14 ◽  
pp. 805-815
Author(s):  
Aleksandra Kołtuniuk ◽  
Magdalena Kazimierska-Zając ◽  
Kinga Cisek ◽  
Justyna Chojdak-Łukasiewicz
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Coping With Stress ◽  
Stress Perception ◽  
Multiple Sclerosis Patients ◽  
And Coping

scholarly journals Physical Exercise Moderates the Effects of Disability on Depression in People with Multiple Sclerosis during the Covid-19 Outbreak

2021 ◽  
Vol 10 (6) ◽  
pp. 1234
Author(s):  
Antonio Carotenuto ◽  
Cristiano Scandurra ◽  
Teresa Costabile ◽  
Luigi Lavorgna ◽  
Giovanna Borriello ◽  
...  
Keyword(s):  
Physical Activity ◽  
Multiple Sclerosis ◽  
Physical Exercise ◽  
Physical Disability ◽  
Psychosocial Wellbeing ◽  
Interaction Plot ◽  
Post Hoc ◽  
Moderating Role

Physical disability impacts psychosocial wellbeing in people with multiple sclerosis. However, the role of physical activity in this context is still debated. By taking advantage of a previous survey, conducted online from 22 April to 7 May 2020, we performed a post-hoc analysis with the aim to assess the associations between disability, physical exercise, and mental health in multiple sclerosis. We retrieved the following data: (i) sociodemographic information, (ii) changes in lifestyle (including exercise), (iii) physical disability, as measured with the Patient-Determined Disease Steps scale, and (iv) anxiety feelings and depressive symptoms assessed via the items included in the Quality of Life in Neurological Disorders measurement system. Examination of the interaction plot showed that the effect of disability on depression, but not on anxious symptoms, was significant for all levels of physical exercise (low: b = 1.22, 95% C.I. 0.85, 1.58, p < 0.001; moderate: b = 0.95, 95% C.I. 0.66, 1.24, p < 0.001; and high: b = 0.68, 95% C.I. 0.24, 1.13, p = 0.003). Based on these data, we can conclude that disability significantly impacted depression during the COVID-19 pandemic, with physical activity playing a moderating role. Our results suggest that favoring exercise in multiple sclerosis (MS) would ameliorate psychological wellbeing regardless of the level of physical disability.

scholarly journals Health Management for Quality of Life of Multiple Sclerosis Patients

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 86-86
Author(s):  
Emily Weiss ◽  
Hyun Kim
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Multiple Sclerosis ◽  
Health Behaviors ◽  
Health Management ◽  
Medical Community ◽  
Physically Active ◽  
Study Results ◽  
Multiple Sclerosis Patients

Abstract Objectives The purpose of this study is to investigate the associations of health behaviors such as diet, sleep and physical activity with quality of life (QoL) for adults diagnosed with Multiple Sclerosis (MS) and other major chronic diseases. The study hypothesizes that healthier diet in addition to an increased level of physical activity is associated with improving overall quality of life for those with MS. Methods The study includes adults aged 40 and older who are registered members of the Michigan Athletic Club in East Lansing, MI, diagnosed with MS, Parkinson's Disease or Arthritis (n = 30). Data on demographic information, previous health history and health behaviors such as mental health, diet, sleep and physical activity are collected. Multivariate regression models are analyzed in order to describe how current health behaviors are associated with quality of life for those with chronic conditions. Results Study results show that physically active MS patients with proper amount and better quality of sleep are likely to have higher overall quality of life. Healthier diet in addition to an increased level of physical activity is also likely to improve overall quality of life for those with MS. Conclusions When the importance of diet, exercise and sleep on MS is understood by the medical community, MS patients can utilize this information to improve their QoL through their own habits. Therefore, this study could lead to better management of symptoms by healthcare professionals and patients, and an improved QoL for those diagnosed with MS. Funding Sources N/A.

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