Effects of a combination of live yeast and yeast cell wall products supplemented before and after weaning on beef heifer growth performance, immune function, and body temperature

2021 ◽  
Vol 37 (6) ◽  
pp. 710-721
Author(s):  
E.A. Palmer ◽  
E.B. Kegley ◽  
P.A. Beck ◽  
J.J. Ball ◽  
J.E. Koltes ◽  
...  
2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 446-447
Author(s):  
Reagan Cauble ◽  
Elizabeth Palmer ◽  
Jeremy Powell ◽  
Matthew Cravey ◽  
Jana Reynolds ◽  
...  

Abstract Live yeast and yeast cell wall products potentially improve health and performance in cattle during the stocker and feedlot phases. Therefore, the objective of this study was to investigate yeast-product supplementation during late gestation through 88 d of age, and(or) a 42-d backgrounding period on immune function and growth performance. Late gestation cows (n = 97) were assigned randomly to treatment: 1) supplement without yeast (CON) or 2) supplement with yeast products (YP). At weaning, calves from each dam treatment (CON or YP) were pooled by dam treatment and stratified based on BW, sex, dam parity, and sire and split into 8 pens within dam treatment. Pens were assigned randomly to 1 of 2 backgrounding treatments (CON or YP) such that a total of 4 pens/treatment existed. Treatments included: 1) dam YP, calf YP, 2) dam YP, calf CON, 3) dam CON, calf YP, and 4) dam CON, calf CON. Calves were fed 2 kg/d of grain and yeast (5 g/d) was provided in a top-dress (ground corn plus YP). Weaning weights (P = 0.99) and backgrounding ADG (P = 0.29) did not differ. Total ruminal VFA concentrations, sampled on d 0 and 42 post-weaning, were increased in calves from dams supplemented with YP (P = 0.04). There were no effects of treatment (P ≥ 0.32) on molar proportions of acetate and propionate. Haptoglobin (P ≥ 0.49) and neutrophil:lymphocyte ratio (P ≥ 0.46) were not influenced by treatment but were affected by day (P < 0.01). While there was no effect of YP (P = 0.73) on BVD titers, there was a day effect (P < 0.01) where titers were greatest on d 28 and least on d 0. Post-weaning yeast supplementation in combination with dam supplementation did not improve calf immune function or performance during a 42-d backgrounding period.


2018 ◽  
Vol 96 (suppl_2) ◽  
pp. 234-234
Author(s):  
E A Palmer ◽  
E B Kegley ◽  
P A Beck ◽  
J J Ball ◽  
J A Hornsby ◽  
...  

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 333-334
Author(s):  
Hyunjin Kyoung ◽  
Myungwoo Cho ◽  
Hanbae Lee ◽  
Sangwoo Park ◽  
Joowon Kang ◽  
...  

Abstract The study was conducted to investigate effects of yeast cell wall product on growth performance, immune responses, and gene expression of tight junction proteins of weaned pigs. A total of 112 weaned pigs (7.98 ± 0.43 kg BW) were randomly assigned to 2 dietary treatments (8 pigs/pen; 7 replicates/treatments) for 4 weeks in a randomized complete block design (block = BW). Dietary treatments were 1) a commercial basal nursery diet (CON) and 2) CON + 0.05% yeast cell wall product (YCW, EasyBio Inc., Seoul, Korea). Blood was collected from one randomly selected pig per pen on d 0, 7, and 14 after weaning. The randomly selected one pig per replicate was euthanized to collect ileum tissue samples at the end of the experimental period. Measurements were growth performance, number of white blood cells (WBC) by an automated hematology analyzer calibrated for porcine blood, cortisol, tumor necrosis factor-α (TNF-α), transforming growth factor-β1, interleukin-1β (IL-1β), and interleukin-6 (IL-6) by the ELISA, and gene expression of tight junction in ileum tissues. Data were analyzed using the PROC GLM procedure of SAS. The statistical model for every measurement included dietary effect and BW as a covariate. Pigs fed YCW had higher (P < 0.10) ADG than those fed CON during overall experimental period. Pigs fed YCW had lower WBC on d 14 (P < 0.10), TNF-α on d 7 (P < 0.10), and decreased IL-1β on d 14 (P < 0.05) than those fed CON. In addition, The YCW increased (P < 0.05) expression of Claudin family, Occludin, Muc1, INF-α, and IL-6, but decreased (P < 0.05) expression of TNF-α genes in the ileum tissues compared with CON. In conclusion, addition of yeast cell wall product in the nursery diet improved growth performance and gut health and modified immune responses of weaned pigs.


Toxins ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 504
Author(s):  
Debora Muratori Holanda ◽  
Alexandros Yiannikouris ◽  
Sung Woo Kim

Pigs are highly susceptible to mycotoxins. This study investigated the effects of a postbiotic yeast cell wall-based blend (PYCW; Nicholasville, KY, USA) on growth and health of newly-weaned pigs under dietary challenge of multiple mycotoxins. Forty-eight newly-weaned pigs (21 d old) were individually allotted to four dietary treatments, based on a three phase-feeding, in a randomized complete block design (sex; initial BW) with two factors for 36 d. Two factors were dietary mycotoxins (deoxynivalenol: 2000 μg/kg supplemented in three phases; and aflatoxin: 200 μg/kg supplemented only in phase 3) and PYCW (0.2%). Growth performance (weekly), blood serum (d 34), and jejunal mucosa immune and oxidative stress markers (d 36) data were analyzed using MIXED procedure of SAS. Mycotoxins reduced (p < 0.05) average daily feed intake (ADFI) and average daily gain (ADG) during the entire period whereas PYCW did not affect growth performance. Mycotoxins reduced (p < 0.05) serum protein, albumin, creatinine, and alanine aminotransferase whereas PYCW decreased (p < 0.05) serum creatine phosphokinase. Neither mycotoxins nor PYCW affected pro-inflammatory cytokines and oxidative damage markers in the jejunal mucosa. No interaction was observed indicating that PYCW improved hepatic enzymes regardless of mycotoxin challenge. In conclusion, deoxynivalenol (2000 μg/kg, for 7 to 25 kg body weight) and aflatoxin B1 (200 μg/kg, for 16 to 25 kg body weight) impaired growth performance and nutrient digestibility of newly-weaned pigs, whereas PYCW could partially improve health of pigs regardless of mycotoxin challenge.


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