Purpose. In modern conditions of the transport services market functioning, the main task of a customer-oriented carrier is to provide high-quality services for the needs of the clientele in cargo transportation, taking into account modern technologies and world experience. The aim of the work is to analyze the existing problems and prospects for organizing piggyback transportation and the effectiveness assessment of this technology application on the example of one of the most potential routes. Methodology. During the research, methods of analysis and synthesis were used to study the main provisions of scientific publications about world experience of organizing piggyback transportation, methods for determining tariffs for cargo transportation and technical - economic calculations for the selected variants. Findings. Ukraine has significant potential for the development of combined transportation, in particular, in international traffic. One of the most efficient and perspective combined transport technologies in the world is a piggyback transportation. A comparative assessment of the shippers’ costs for cargo transportation using different technologies between the terminals Dnepr-Liski and Chop has been carried out. Scientific novelty. The obtained results make it possible to provide a scientific and economic basis for the selection of expedient variants for combined cargo transportation. Practical value. The obtained results of the analysis of the use effectiveness of piggyback technology, taking into account the existing tariffs and competition with road transport on the specific logistics route, can be used for a preliminary assessment and decision-making about the use of different types of combined transport as an alternative to direct road or rail cargo transportation.