Keratocystic odontogenic tumor

ABSTRACT Objective: to evaluate the frequency of keratocystic odontogenic tumor (KOT) in the Oral Surgery Service (OSS) of the University Hospital Clementino Fraga Filho of the Federal University of Rio de Janeiro (HUCFF / UFRJ), with respect to recurrence rate, gender, age of recurrence and location of the injury Methods: clinical records were reviewed and histopathological reports of KOT patients of the HUCFF/UFRJ between 2002 and 2012. Patients diagnosed with KOT were divided into two groups for the occurrence of relapse: positive (n=6) and negative (n=19) Results: regarding the location, there was a predilection for the mandible. In the average age of patients in the positive group was 40.5 and the negative group, 35.53. In the distribution by gender, positive group showed equal distribution, different from that observed in the negative group, which showed a predilection for males Conclusion: KOT was the second most frequent injury in our patients, recurrence was lower among males and had the jaw as most affected location

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Dental pathologies in tumor patients with bone metastases or multiple myeloma scheduled for antiresorptive therapy

Future Oncology ◽

10.2217/fon-2020-1240 ◽

2021 ◽

Author(s):

Johannes Laimer ◽

Martin Hechenberger ◽

Daniela Müller ◽

Benjamin Walch ◽

Andreas Kolk ◽

...

Keyword(s):

Multiple Myeloma ◽

Oral Surgery ◽

Osteonecrosis Of The Jaw ◽

University Hospital ◽

Antiresorptive Therapy ◽

Jaw Cysts ◽

Dental Focus ◽

Antiresorptive Drugs ◽

The University ◽

Tooth Extractions

Background: Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe complication of mainly antiresorptive drugs. We evaluated the frequency of dentoalveolar pathologies in patients scheduled for antiresorptive therapy in a ‘real-world’ setting, also including patients with poor oral health potentially requiring tooth extractions and/or other dentoalveolar surgery. This approach is in contrast to the setting of recent randomized trials with restrictive exclusion criteria. Patients & methods: We prospectively included patients suffering from solid tumors with osseous metastases or multiple myeloma. Screening for dentoalveolar pathologies was done prior to initiation of antiresorptive therapy at the specialized MRONJ clinic of the University Hospital for Cranio-Maxillofacial and Oral Surgery, Innsbruck, Austria. Results: 119 subjects could be included. In 76 patients (63.9%), a dental focus was revealed including deep caries (24.4% of patients), chronic apical periodontitis (26.9%), periodontal disease (45.8%), root remnants (16%), jaw cysts (2.5%), partially impacted teeth (5.0%) and peri-implantitis (5.0%). Conclusion: Considering the high number of dentoalveolar pathologies (63.9%), systematic dental focus screening prior to initiation of antiresorptive therapy is of utmost importance to lower the risk for MRONJ.

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Abstract 2753: Initial and 24h After Admisson DWI Can Predict Recurrence of Ischemic Event of TIA Patients

Stroke ◽

10.1161/str.43.suppl_1.a2753 ◽

2012 ◽

Vol 43 (suppl_1) ◽

Author(s):

Yasuyuki Iguchi ◽

Kazumi Kimura ◽

Jyunya Aoki ◽

Kazuto Kobayashi ◽

Kenichiro Sakai ◽

...

Keyword(s):

Recurrence Rate ◽

Negative Group ◽

Initial Examination ◽

Ischemic Lesion ◽

Ischemic Event ◽

Positive Group ◽

Significant Difference ◽

Weighted Magnetic Resonance Imaging ◽

Ischemic Attack

Background and Purpose Our aim is to investigate the diagnostic utility of diffusion weighted magnetic resonance imaging (DWI) for transient ischemic attack (TIA), not only admission but also 24 h after first study. Methods We prospectively enrolled TIA patients who were admitted within 24 h of onset. We examined trans-thoracic echocardiography, 24 h Holter electrocardiography, and carotid duplex ultrasonography in order to give the best medication. All of patients received DWI immediately after admission. At first, when we observed hyper-intense lesion considered as ischemia, additional DWI examination was not conducted. When there was no hyper-intense lesion on initial DWI study, we conducted follow-up DWI 24 h after initial examination. We defined a recurrence of ischemic event as an occurrence of symptomatic ischemic stroke or TIA at 3 months after onset. Regarding initial DWI study, we compared proportional frequency of recurrence between patients with ischemic lesion (i-positive group) and without any lesion (i-negative group), and also compared recurrence rate between patients with ischemic lesion on initial and/or follow-up studies (if-positive group) and without any lesion on both studies (if-negative group). Results We registered 100 TIA patients (men; 63, median age; 74 years, ABCD2 score <3; 32). On initial DWI study, 34 patients had ischemic lesion (i-positive group) and 66 had no lesion (i-negative group). Among 66 patients of i-negative group, 12 (19%) had hyper-intense lesion in follow-up study. Finally, there were 46 patients in if-positive group and 54 in if- negative. Recurrence ischemic event occurred in 19 (19%) of 100 patients. There was no significant difference of recurrence rate between i-positive and i-negative groups (27% vs. 16%, p=0.172). However, recurrence rate was significantly higher in if-positive group than these of if-negative group (29% vs. 12%, p=0.024) Conclusions New ischemic lesions on follow up DWI appeared in approximately 20% of TIA patients who did not have ischemic lesion on initial DWI. Only initial DWI but initial and follow-up DWI was important role of predicting the recurrence of ischemic events in TIA patients.

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Does the Excision of Overlying Oral Mucosa Reduce the Recurrence Rate in the Treatment of the Keratocystic Odontogenic Tumor? A Systematic Review and Meta-Analysis

Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.joms.2016.03.043 ◽

2016 ◽

Vol 74 (10) ◽

pp. 1974-1982 ◽

Cited By ~ 10

Author(s):

Essam Ahmed Al-Moraissi ◽

M. Anthony Pogrel ◽

Edward Ellis

Keyword(s):

Systematic Review ◽

Recurrence Rate ◽

Oral Mucosa ◽

Meta Analysis ◽

Odontogenic Tumor ◽

Keratocystic Odontogenic Tumor

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Ectopic schistosomiasis: description of five cases involving skin, one ovarian case and one adrenal case

Revista da Sociedade Brasileira de Medicina Tropical ◽

10.1590/s0037-86822008000600021 ◽

2008 ◽

Vol 41 (6) ◽

pp. 668-671 ◽

Cited By ~ 10

Author(s):

Wendell Luiz Santos Poderoso ◽

Wagner Barreto de Santana ◽

Emerson Ferreira da Costa ◽

Rosana Cipolotti ◽

Ricardo Fakhouri

Keyword(s):

Adjuvant Chemotherapy ◽

The State ◽

Age At Diagnosis ◽

University Hospital ◽

Embryonic Carcinoma ◽

Praziquantel Treatment ◽

Clinical Records ◽

The University

Seven cases of patients with ectopic schistosomiasis from the State of Sergipe, Brazil, are presented (five involving skin, one ovarian and one adrenal). Data were collected from surveying the clinical records and anatomopathological reports in the files of the dermatology and pathology clinics of the University Hospital of the Federal University of Sergipe, from 1995 to 2005. The patients' mean age at diagnosis was 21.1 years. In the dermatological cases, full cures were achieved after treatment with oxamniquine. In the ovarian case, there was an association with embryonic carcinoma: this patient underwent surgery with adjuvant chemotherapy and praziquantel treatment, with satisfactory evolution. The adrenal case was associated with adenoma.

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Facial Injuries Due to Criminal Violence: A Retrospective Study of Hospital Attenders

Medicine Science and the Law ◽

10.1177/002580249203200411 ◽

1992 ◽

Vol 32 (4) ◽

pp. 345-353 ◽

Cited By ~ 9

Author(s):

C Ström ◽

G Johanson ◽

Å Nordenram

Keyword(s):

Women Victims ◽

Oral Surgery ◽

Nasal Bone ◽

Fracture Site ◽

University Hospital ◽

Patient Records ◽

Criminal Violence ◽

Assault Victims ◽

The University ◽

Nose And Throat

The material comprised 222 assault victims whose injuries required attention at the Departments of Oral Surgery and Ear, Nose, and Throat diseases, the Central Hospital in Falun or corresponding departments at the Karolinska Institutet, Stockholm or the University Hospital in Huddinge. Information was obtained from patient records. One hundred and thirty-eight patients had fractures and the remainder had flesh-wounds, haematomas or swellings. The most frequent fracture site was the nasal bone followed by the jaws. Forty-one per cent of the patients in Falun and 28 per cent in Stockholm reported the assaults to the police: in Falun the proportion of women victims who reported the assault was significantly higher than those who did not. The willingness to notify the police of the violence was not influenced by the use of drugs or the seriousness of the injuries. The study showed that violence in suburban Stockholm was aggravated: one-third of the patients in the study required hospitalization compared to a quarter in a rural area.

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Epidemiology and Hospital Course of Patients With Acute Salpingitis and Coincident HIV

Infectious Diseases in Obstetrics and Gynecology ◽

10.1155/s1064744993000213 ◽

1993 ◽

Vol 1 (2) ◽

pp. 91-93

Author(s):

Iris Ayala-Rodriguez ◽

Joseph Apuzzio

Keyword(s):

Hospitalized Patients ◽

University Hospital ◽

Hiv Positive ◽

Negative Group ◽

Positive Group ◽

Immunodeficiency Virus ◽

The Mean ◽

Wbc Count ◽

Hiv Seropositive ◽

Hiv Negative

Objective: To compare the epidemiology and hospital course of patients with acute salpingitis with and without coincident human immunodeficiency virus (HIV) seropositivity.Methods: Patients admitted to the UMDNJ-University Hospital in Newark, New Jersey from January 1, 1991, to December 31, 1991, with acute salpingitis were studied.Results: Eight percent of all hospitalized patients with acute salpingitis were HIV-positive. The mean age of the HIV-negative group was 25.4 compared with 29.6 years in the HIV-positive group. Gonorrhea and chlamydia were present in 49% and 22%, respectively, in HIV-negatives and in 40% and 20% of HIV-positives. Two of 5 (40%) HIV-positive patients had tuboovarian abscesses compared with 12 of 59 (20%) HIV-negative patients. Three of 5 (60%) HIV-positive patients had admission WBC counts fewer than 10,000/mm3 compared to 6 of 59 (12%) of HIV-negatives (P = 0.024). The hospital stay was 5.4 days for HIV-positives and 5.8 days for HIV-negatives.Conclusions: Eight percent of hospitalized patients with acute salpingitis were HIV-seropositive. Neisseria gonorrhoeae and chlamydia were commonly found organisms in both groups. The initial WBC count was lower for HIV-positive patients. The hospital course of both groups was similar.

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Utility of prophylactic antibiotics for preventing febrile neutropenia during cabazitaxel therapy for castration-resistant prostate cancer

Scientific Reports ◽

10.1038/s41598-021-87758-y ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Keitaro Watanabe ◽

Takeo Kosaka ◽

Hiroshi Hongo ◽

Mototsugu Oya

Keyword(s):

Prostate Cancer ◽

Febrile Neutropenia ◽

Prophylactic Antibiotics ◽

University Hospital ◽

Negative Group ◽

Castration Resistant Prostate Cancer ◽

Chi Square ◽

Positive Group ◽

Castration Resistant ◽

Chi Square Test

AbstractThe aim was to investigate the efficacy of prophylactic antibiotics for the prevention of febrile neutropenia (FN) during cabazitaxel therapy for castration-resistant prostate cancer (CRPC) with G-CSF. We retrospectively studied 443 cycles of cabazitaxel therapy given to 56 patients with CRPC at Keio University Hospital between May 2012 and August 2018. Statistical analysis was conducted to determine whether the combination of prophylactic G-CSF and antibiotics was more effective in preventing FN, compared with prophylactic G-CSF alone. Prophylactic PEG-G-CSF or G-CSF was administered in all 443 cycles. Only fluoroquinolones were used as prophylactic antibiotics and were administered in 328 cycles (74.0%). FN occurred in 5 cycles (1.1%). Prophylactic antibiotics were administered in 327 cycles (74.6%) in the FN-negative group and in only 1 cycle (20.0%) in the FN-positive group. Chi-square test indicated the incidence of FN was significantly lower in the group that received prophylactic antibiotics compared with the group that did not receive prophylactic antibiotics (P = 0.017). Compared with prophylactic G-CSF alone, prophylactic G-CSF and antibiotics significantly suppressed the occurrence of FN.

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Pregnancy outcomes in women with a hemoglobinopathy trait: a multicenter, retrospective study

Archives of Gynecology and Obstetrics ◽

10.1007/s00404-021-06058-y ◽

2021 ◽

Author(s):

Jan Kasparek ◽

Tilo Burkhardt ◽

Irene Hoesli ◽

Gabriela Amstad Bencaiova

Keyword(s):

Pregnant Women ◽

Neonatal Outcomes ◽

University Hospital ◽

Control Group ◽

Maternal Outcomes ◽

Adverse Neonatal Outcomes ◽

Maternal And Neonatal Outcomes ◽

Clinical Records ◽

The University ◽

Fetal Acidosis

Abstract Purpose To determine the risk of adverse maternal and neonatal outcomes in pregnant women with a hemoglobinopathy trait. Materials and methods Retrospective cohort study was conducted to compare adverse maternal and neonatal outcomes between pregnant women with a hemoglobinopathy trait (study group; n = 172), and without a hemoglobinopathy trait (control group; n = 360). The medical data were extracted from clinical records of pregnant women attending antenatal care and delivering at the University Hospital Basel or University Hospital Zurich between 2015 and 2018. Results A total of 172 pregnant women with a hemoglobinopathy trait and 360 controls were recruited. Apart from fetal acidosis, the groups did not differ significantly in any variables of adverse neonatal outcomes. Whereas, among the maternal outcomes the rate of abortion, gestational diabetes mellitus, bacteriuria or urinary tract infection, intrahepatic cholestasis, abnormal placentation and anemia postpartum were significantly increased in women with a hemoglobinopathy trait. Conclusion In our study, a hemoglobinopathy trait increased the risk of adverse maternal outcomes but did not increase adverse neonatal outcomes.

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