scholarly journals Pituitary macroadenoma presenting as a nasal tumor: case report

2014 ◽  
Vol 132 (6) ◽  
pp. 377-381 ◽  
Author(s):  
Nivaldo Adolfo Silva Junior ◽  
Fabiano Reis ◽  
Larissa Kaori Miura ◽  
Guilherme Henrique Vieira ◽  
Luciano Souza Queiroz ◽  
...  
Keyword(s):  
Pituitary Adenoma ◽  
Nasal Cavity ◽  
Nasal Obstruction ◽  
Sphenoid Sinus ◽  
Sella Turcica ◽  
Rare Condition ◽  
Lower Surface ◽  
Large Mass ◽  
Histopathological Analysis ◽  
Tumor Extension

CONTEXT: Pituitary macroadenomas are rare intracranial tumors. In a few cases, they may present aggressive behavior and invade the sphenoid sinus and nasal cavity, causing unusual symptoms. In this paper, we report an atypical case of pituitary adenoma presenting as a nasal mass.CASE REPORT: The patient was a 44-year-old woman who had had amenorrhea and galactorrhea for ten months, with associated nasal obstruction, macroglossia and acromegaly. Both growth hormone and prolactin levels were increased. Magnetic resonance imaging showed a large mass originating from the lower surface of the pituitary gland, associated with sella turcica erosion and tumor extension through the sphenoid sinus and nasal cavity. Histopathological analysis demonstrated a chromophobe pituitary adenoma with densely packed rounded epithelial cells, with some atypias and rare mitotic figures. There was no evidence of metastases.CONCLUSION: Macroadenoma invading the nasal cavity is a rare condition and few similar cases have been reported in the literature. This study contributes towards showing that tumor extension to the sphenoid sinus and nasopharynx needs to be considered and investigated in order to make an early diagnosis when atypical symptoms like nasal obstruction are present.

scholarly journals Collision Occurrence of Sinonasal Carcinosarcoma and Pituitary Adenoma: A Case Report and Literature Review.

2020 ◽  
Author(s):  
Yufei Liu ◽  
Jihu Yang ◽  
Xiejun Zhang ◽  
Yanhua Sun ◽  
Fanfan Chen ◽  
...  
Keyword(s):  
Pituitary Adenoma ◽  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Large Mass ◽  
Cranial Base ◽  
Endonasal Approach ◽  
Ki 67 ◽  
Expanded Endonasal Approach ◽  
Anterior Cranial Base

Abstract BACKGROUND: Collision occurrences of sinonasal carcinosarcoma and pituitary adenoma are rarely reported. Sinonasal carcinosarcomas represent rare neoplasms with invasive characteristics and unfavorable prognoses.CASE DESCRIPTION: We present a rare case of a collision occurrence of sinonasal carcinosarcoma and pituitary adenoma in a 45‐year‐old male patient. MRI demonstrated a large mass involving the sellar region, nasal cavity, paranasal sinuses and anterior cranial base. Total surgical resection with a pure endoscopic expanded endonasal approach was performed successfully with neuronavigational assistance. Histopathologic results were a carcinosarcoma in the nasal cavity, paranasal sinuses, and anterior cranial base and a pituitary adenoma in the intrasellar zone. The Ki-67 index of the carcinosarcoma was high (more than 95%). Although the patient received chemotherapy, he died 6 months after surgery because of in situ recurrence and extensive metastatic growth.CONCLUSIONS: Collision occurrences of sinonasal carcinosarcoma and pituitary adenoma are rare events. Such tumor could be removed successfully by neuronavigational guidance with a pure endoscopic expanded endonasal approach. A contralateral nasal septum mucosa flap without tumor invasion can be used as a kind of skull base repair material. A high Ki-67 index may be a biomarker of rapid tumor progression and poor prognosis in such patients.

scholarly journals Cerebrospinal fluid fistula as the presenting manifestation of pituitary adenoma: case report with a 4-year follow-up

2001 ◽  
Vol 59 (2A) ◽  
pp. 263-265 ◽  
Author(s):  
Ricardo Alexandre Hanel ◽  
Daniel Monte Serrat Prevedello ◽  
Alceu Correa ◽  
Affonso Antoniuk ◽  
João Cândido Araújo
Keyword(s):  
Cerebrospinal Fluid ◽  
Pituitary Adenoma ◽  
Sella Turcica ◽  
Rare Condition ◽  
Normal Serum ◽  
Cerebrospinal Fluid Fistula ◽  
Csf Rhinorrhea ◽  
Csf Leakage ◽  
Bony Erosion

We report the case of a young woman who presented with cerebrospinal fluid (CSF) rhinorrhea due to an undiagnosed and untreated pituitary adenoma. The tumor had extended well beyond sella turcica and caused bony erosion. The patient initially refused surgery and was treated with bromocriptine and a radiation therapy. CSF leakage did not improved and she was submitted to surgery by the transsphenoidal approach with removal of a tumor mass located in sphenoid sinus and sellar region. Origin of the leak was localized and repaired with fascia lata and a lumbar subarachnoid drain was left in place for 5 days. After 4 years she has normal serum PRL levels and no rhinorrhea. The management, complications and mechanisms involved in this rare condition are discussed.

scholarly journals Rhinolithiasis: A Rare Clinical Case

2021 ◽  
pp. 23-26
Author(s):  
Sylvain Diembi ◽  
Harol Boris Otouana ◽  
Gerard Chidrel Gouoni ◽  
A Tsieri Tsoba ◽  
Brice Diabassana ◽  
...  
Keyword(s):  
Foreign Body ◽  
Ct Scan ◽  
Nasal Cavity ◽  
Nasal Obstruction ◽  
Endoscopic Surgery ◽  
Clinical Case ◽  
Current Practice ◽  
Rare Condition ◽  
Therapeutic Management ◽  
Positive Diagnosis

Rhinolithiasis is a rare condition in our current practice. We report the case of a 19 year old woman, presenting with a double symptom marked by rhinorrhea and chronic unilateral nasal obstruction evolving since the age of 7 years, without any known foreign body. Rhinoscopy and nasal endoscopy coupled with CT scan were decisive examinations for the positive diagnosis. The therapeutic management consisted in the extraction of the rhinolithiasis resulting in the vacuity of the nasal cavity. The evolution was favorable with simple postoperative courses. Keywords: Rhinolithiasis; Woman; Rhinoscopy; Endoscopic Surgery

scholarly journals Newborn Nasal Obstruction due to Congenital Nasal Pyriform Aperture Stenosis

2016 ◽  
Vol 7 (1) ◽  
pp. ar.2016.7.0146 ◽  
Author(s):  
Thiago L. I. Serrano ◽  
Leopoldo Pfeilsticker ◽  
Vanessa Silva ◽  
Igor Hazboun ◽  
Jorge Paschoal ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Respiratory Distress ◽  
Nasal Cavity ◽  
Nasal Obstruction ◽  
Treatment Strategies ◽  
Rare Condition ◽  
Surgical Correction ◽  
Severe Respiratory Distress ◽  
First Case ◽  
Pyriform Aperture

Introduction Nasal obstruction is an important condition that can lead to severe respiratory distress in newborns. There are several differential diagnoses, and one of them is congenital nasal pyriform aperture stenosis (CNPAS). CNPAS is a rare case of respiratory distress caused by excessive growth of the nasal process of the maxilla and leads to narrowing of the anterior third of the nasal cavity. Diagnosis, associated anomalies, and treatment strategies are reviewed by the following presentation of two cases. Case Presentation We report two cases of infants diagnosed with CNPAS. The patients in the first case had no concomitant comorbidities, and the outcome was successful after surgical correction of stenosis. The patient in the second case had an associated holoprosencephaly, and although surgical correction and nasal cavity patency, the patient remains dependent on tracheostomy due to dysphagia and neurologic impairment. Discussion Airway obstruction affects 1 in 5000 children, and CNPAS is a diagnosis frequently forgotten and even unknown to neonatal and pediatric intensivists. Newborns are obligate nasal breathers, and, nasal obstruction, therefore, can lead to severe respiratory distress. CNPAS is not only rare but, many times, is not easily recognized. It is important to bear in mind the diagnostic criteria when evaluating infants with nasal obstruction. Conservative treatment should be prioritized, but surgical treatment is required in severe cases with failure to thrive and persistent respiratory distress. Respiratory distress and dysphagia may persist to some degree despite correction of the stenotic pyriform aperture due to associated narrowing of the entire nasal cavity and association with other anomalies. Final Comments CNPAS is a rare condition and may be lethal in newborns. Differential diagnosis of nasal obstruction must be remembered to recognize this anomaly, and the otolaryngologist must be familiarized with this condition and its diagnosis. Precise surgical treatment in severe cases have high rates of success in children without other comorbidities.

Immunoglobulin G4 related disease isolated to the nasal cavity: a rare cause of nasal obstruction

2014 ◽  
Vol 129 (S1) ◽  
pp. S57-S59 ◽  
Author(s):  
C Morris ◽  
T Ng ◽  
P Kevin ◽  
N Singh
Keyword(s):  
Case Report ◽  
Nasal Cavity ◽  
Nasal Obstruction ◽  
Rare Condition ◽  
Imaging Findings ◽  
Immunoglobulin G4 ◽  
Related Disease ◽  
Oral Corticosteroids ◽  
Anterior Septum

AbstractBackground:Immunoglobulin G4 related disease is a rare condition. Cases involving the sinonasal region are exceptionally uncommon. This paper describes a case of immunoglobulin G4 related disease isolated solely to the nasal cavity.Methods:Case report and literature review.Results:A 34-year-old man presented with painless, progressive bilateral nasal obstruction. Clinical examination and imaging findings demonstrated bilateral submucosal swelling of the anterior septum and right external nasal wall. Biopsy revealed immunoglobulin G4 related disease. The patient responded to oral corticosteroids initially, followed by long-term methotrexate.Conclusion:To the best of our knowledge, this case represents the first report in the literature of immunoglobulin G4 related disease isolated solely to the nasal cavity.

scholarly journals Sphenochoanal polyp

2021 ◽  
Vol 4 (3) ◽  
pp. 127-129
Author(s):  
Ankita Yadav ◽  
Ginni Datta ◽  
Amarjeet
Keyword(s):  
Nasal Cavity ◽  
Nasal Obstruction ◽  
Sphenoid Sinus ◽  
Sinus Surgery ◽  
Nasal Endoscopy ◽  
Antrochoanal Polyp ◽  
Polypoidal Mass ◽  
Rare Tumours ◽  
Sphenochoanal Polyp ◽  
The Right

Sphenochoanal polyp are rare tumours arising from sphenoid sinus. The main presenting complain is gradually progressing nasal obstruction. Sphenochoanal polyp mimics antrochoanal polyp clinically. To differentiate it from antrochoanal polyp, diagnostic nasal endoscopy, computer tomography and magnetic resonance imaging of the paranasal sinuses are the investigation of choice. Functional endoscopic sinus surgery is the line of treatment.: A 33years old female presented with right nasal obstruction since 2 years. On Diagnostic nasal endoscopy polypoidal mass was seen partially obliterating the right nasal cavity not arising from middle meatus. CT scan showed polypoidal mass obliterating the nasal cavity, choana and Sphenoid sinus. It was completely excised by functional endoscopic surgery.We present this rare case to highlight the use of diagnostic nasal endoscopy and Computed Tomography in the diagnosis and treatment of Sphenochoanal polyps

scholarly journals Leiomyosarcoma of the Nasal Cavity

2020 ◽  
pp. 014556132096120
Author(s):  
Rakan Saadoun ◽  
Theresa Obermueller ◽  
Mareike Franke ◽  
Angela Schell ◽  
Kersten Mückner ◽  
...  
Keyword(s):  
Nasal Cavity ◽  
Case Reports ◽  
Tumor Resection ◽  
Bone Destruction ◽  
Rare Condition ◽  
Nasolacrimal Duct ◽  
Resection Margins ◽  
Histopathological Analysis ◽  
Left Nasal Cavity ◽  
Data Set

Leiomyosarcoma (LMS) in the sinonasal tract (SNT) is a rarity that has been firstly described in 1958. Since then, there have been only a few articles about this entity. Most of the data available about LMS in the SNT is derived from case reports. We believe that our case will support the data set and help guiding the management of this rare condition. A 84-year-old female presented with nasal airway obstruction on the left side. She experienced several episodes of epistaxis from her left nostril, what made her to seek medical care. A rhinoscopy revealed an obstructing mass in the left nasal cavity. Computed tomography (CT) scan of the paranasal sinuses revealed a homogenous mass occupying the left nasal cavity, bone destruction of the left middle, and inferior nasal turbinates. An infiltration of the left nasolacrimal duct was also present. The patient refused to undergo open surgery and the mass was removed during an endoscopic approach. The histopathological analysis combined with immunohistochemistry was consistent with LMS. The resection margins were positive for tumor cells. A staging with CT-neck-thorax, abdomen ultrasound, and MRI of the head ruled out metastases. She underwent a second endoscopic tumor resection surgery with positive resection margins and obtained adjuvant radiotherapy. On 9 months of follow-up, there was no recurrence or metastases.

scholarly journals Osteoblastoma of the ethmoid

2012 ◽  
Vol 01 (01) ◽  
pp. 086-088
Author(s):  
M.D. Venkatesh ◽  
Prabal Deb ◽  
Harjinder Bhatoe
Keyword(s):  
Nasal Cavity ◽  
Skull Base ◽  
Nasal Obstruction ◽  
Frontal Lobes ◽  
Large Mass ◽  
Clinical Record ◽  
Team Approach ◽  
Rare Tumor ◽  
Endonasal Approach

Abstract Osteoblastoma is a rare, benign bony tumor of skull base. We report one such case. Clinical record. We reviewed the record of a 21-year-old-male, who presented with nasal obstruction and proptosis. The tumor had formed a large mass that displaced the frontal lobes, the orbits and projected into the nasal cavity. Imaging revealed a calcified nodular expansile lesion. The tumor could be excised near-total by bifrontal craniotomy combined with endonasal approach. Histopathology was confirmatory of osteoblastoma. The patient was discharged on the seventh postoperative day and is now on follow-up. Osteoblastoma is a rare tumor of the frontoethmoid region. Surgery requires meticulous planning and team approach.

scholarly journals Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yi Zhang ◽  
Cheng Chen ◽  
Min Lin ◽  
Kan Deng ◽  
Huijuan Zhu ◽  
...  
Keyword(s):  
Case Report ◽  
Pituitary Adenoma ◽  
Literature Review ◽  
Pituitary Adenomas ◽  
Sella Turcica ◽  
Infertile Woman ◽  
Mass Treatment ◽  
Successful Pregnancy ◽  
Case Presentation ◽  
Transsphenoidal Resection

Abstract Background Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual. Case presentation A 30-year-old woman with elevated LH and normal FSH presented with inability to conceive. An MRI revealed an enlarged sella turcica and an intrasellar mass. Treatment with transsphenoidal resection led to normalization of LH and estradiol, as well as successful pregnancy. And we reviewed 6 cases of LH-secreting pituitary adenomas from 1981 to 2020. Conclusions Our case is unique because of the LH-secreting pituitary adenoma without FSH hypersecretion. This case indicates that pituitary adenoma should be considered when other diseases causing infertility have been excluded.

scholarly journals Pituitary adenoma presenting with nasal obstruction: A case report

2021 ◽  
Vol 18 ◽  
pp. 100259
Author(s):  
Mitchell McDonough ◽  
Andre Le Roux ◽  
Christopher J. Chin
Keyword(s):  
Case Report ◽  
Pituitary Adenoma ◽  
Nasal Obstruction
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