scholarly journals Study of feto-maternal outcome in patients with hepatitis E infection during pregnancy

2022 ◽  
Author(s):  
Dipti M. Shah ◽  
Prakash P. Prajapati ◽  
Munjal J. Pandya ◽  
Nimisha J. Chaudhary ◽  
Gira C. Dabhi
Keyword(s):  
Mortality Rate ◽  
Pregnant Women ◽  
Maternal Morbidity ◽  
Monsoon Season ◽  
Fetal Monitoring ◽  
Hepatitis E ◽  
Maternal Outcome ◽  
Morbidity And Mortality ◽  
Third Trimester ◽  
Maternal Morbidity And Mortality

Background: Hepatitis E is considered as a common cause of high maternal morbidity and mortality particularly in third trimester and also high perinatal morbidity and mortality. Thus, this study is conducted to evaluate the feto-maternal outcome in patients infected with hepatitis E during pregnancy.Methods: It is a retrospective observational study conducted in department of obstetrics and gynecology at L. G. hospital. Fifty pregnant women with clinical hepatitis in third trimester of pregnancy were included in this study and thorough investigation were carried out. Patients were monitored till postpartum period and fetal monitoring data were collected from neonatal ICU.Results: In this study, majority of pregnant patients with hepatitis B were admitted during monsoon season suggests that HEV outbreaks are more common during monsoon months. Majority of the patients (70%) were emergency cases. Majority of these patients (82%) were belonged to lower socio-economic class. Co-infection with HAV was in 2% and with HBV in 4%. S. bilirubin >15 mg/dl in 16% of patients. PT and APTT were raised in 28% of patients. FDP was raised in 70% of patients. 76% were delivered vaginally and 22% were delivered by LSCS. Most common complication in HEV infected pregnant women was disseminated intravascular coagulation (DIC) (26%). Maternal mortality rate is 14%. Out of 50 patients, 88% delivered live baby, out of which 72% needed NICU admission. Perinatal mortality rate was as high as 28%.Conclusions: Hepatitis E infection and pregnancy is a deadly and fatal combination. Specifically, in 3rd trimester of pregnancy, acute hepatitis E has a grave prognosis with high maternal morbidity and mortality. Prevention is the mainstay of controlling HEV especially in developing countries.

scholarly journals A study on faeto-maternal outcome in pregnancy with jaundice due to hepatitis E

2017 ◽  
Vol 6 (3) ◽  
pp. 861
Author(s):  
Sushanta Kumar Jena ◽  
Minakshi Mohanty ◽  
Sasmita Behuria
Keyword(s):  
Pregnant Women ◽  
Hepatitis E Virus ◽  
Rna Virus ◽  
Hepatitis E ◽  
Oral Route ◽  
Maternal Outcome ◽  
Third Trimester ◽  
Medical College ◽  
Maternal Morbidity And Mortality ◽  
Careful Management

Background: Hepatitis E virus is a non-envelope RNA virus responsible for large epidemics in Asia, the Middle east Mexico and Africa. It spreads via the feco-oral route, and has an incubation period of 8-10 weeks. The objective of the study was to find out the effect of hepatitis E during pregnancy on faeto-maternal outcome.Methods: A study on faeto-maternal outcome of 38 pregnant women admitted with jaundice due to hepatitis E to the Department of Hepatology, Shri Ramachandra Bhanj (SCB) Medical College, Cuttack, Odisha, India during January 2015 to December 2015.Results: 38 Pregnant women admitted to the Department of Hepatology of SCB Medical College, Cuttack, Odisha, India were studied. 65.7% were from rural area, 92.1% were in their third trimester of pregnancy. Serum bilirubin >10 mg in 52.19 %, SGOT, SGPT and alkaline phosphatase were raised in majority of them. Out of 38 women 32 delivered and 6 remain undelivered. In 81.25% of cases labor was spontaneous, perinatal mortality was observed in 46.87% of cases and 5 women died during child birth.Conclusions: When pregnancy is associated with jaundice due to hepatitis E, there is high perinatal and maternal morbidity and mortality. Early diagnosis and careful management is required for such cases.

scholarly journals The screening of heart disease by cardiac auscultation and electrocardiography examination in pregnant women in Puskesmas Tegalrejo, Yogyakarta, Indonesia

2021 ◽  
Vol 4 (3) ◽  
pp. 155
Author(s):  
Lucia Kris Dinarti ◽  
Detty Siti Nurdiati ◽  
Anggoro Budi Hartopo ◽  
Fika Humaeda Assilmi ◽  
Alifia Salsabila ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Pregnant Women ◽  
Maternal Morbidity ◽  
Screening Program ◽  
Screening Method ◽  
Morbidity And Mortality ◽  
Cardiac Auscultation ◽  
Heart Murmurs ◽  
Maternal Morbidity And Mortality ◽  
Secondary Screening

Women adapt to pregnancy through multi-organ system physiologic changes, including cardiovascular adaptations. These changes affect those with pre-existing cardiovascular problems differently, and subsequently lead to higher probability of death caused by cardiovascular diseases during pregnancy. Therefore, detection of cardiovascular disease early in pregnancy is important to lower maternal morbidity and mortality by providing prompt and adequate management. This study aimed to evaluate and test the feasibility of integrating 12-lead electrocardiogram (ECG) examination and antenatal care (ANC) screening as a simple and effective method for early detection of heart abnormality in pregnant woman. Pregnant women were recruited in this study in any trimester who attended ANC for a routine pregnancy examination in Puskesmas Tegalrejo Yogyakarta. The subjects underwent primary screening which focused on cardiac auscultation and 12-lead ECG examinations, and those who had abnormal findings were further followed-up in secondary screening by using trans-thoracic echocardiography to confirm heart abnormality. A total of 523 pregnant women from Puskesmas Tegalrejo were included in this study. 15 (2.8%) pregnant woman were suspected to have heart abnormalities; from those, 3 (0.5%) were found with heart murmurs with abnormal ECG readings, 1 (0.19%) had heart murmurs with normal ECG results, and 11 (2.1%) had abnormal ECG readings only. The secondary screening of those patients resulted in 1 (0.19%) pregnant woman who was diagnosed with Atrial Septal Defect. Our study found that among 15 patients identified with suspected ECG abnormalities, one mother who underwent ANC was newly diagnosed with a pre-existing cardiac abnormality. Our study concluded this screening method is a simple and feasible integrated heart screening program that can be implemented widely. We hope this integrated heart screening program may benefit pregnant women who may have cardiac abnormalities to be detected as early as possible, thus reducing maternal morbidity and mortality.

scholarly journals FETOMATERNAL OUTCOME IN PREGNANCY WITH CARDIAC DISEASE

2021 ◽  
Vol 5 (7) ◽  
Author(s):  
Kalyani K Bafna ◽  
Kanaklata Nakum ◽  
Aditi Vithal
Keyword(s):  
Heart Disease ◽  
Pregnant Women ◽  
Cardiac Disease ◽  
Maternal Morbidity ◽  
Nyha Class ◽  
Mode Of Delivery ◽  
Fetal Outcome ◽  
Morbidity And Mortality ◽  
Maternal Complications ◽  
Maternal Morbidity And Mortality

Objective(S): Cardiac disease is an important cause of maternal morbidity and mortality in both antepartum as well as in postpartum period. Incidence of heart disease with pregnancy is <1%. Aim of this study is to determine maternal complications with heart disease, mode of delivery & fetal complications. Materials & Methodology: This is a retrospective study conducted at Gopinath Maternity Home, Sir-T Hospital, Bhavnagar. From May 2020- April 2021. All pregnant women with various cardiac disease (previously established or diagnosed during pregnancy) who came to labor room or OPD are included. Result: 30 pregnant women out of 2683 deliveries were identified with cardiac disease giving prevalence of 1.12% in this study. 15(50%) women belonging to NYHA class-1 & 8(26.6%) belonged to NYHA class 2. Class 3(3 patients =10%) & class 4(4patients= 13.3%) were admitted immediately. 18(60%) women were case of valvular heart disease, out of which 12(66.6%) cases were of RHD, 2(11.1%) were MS, 3(16.6%) AS, 1(5.5%) MR. 10(33.33%) cases were congenital heart disease. Maternal mortality were 4(13.33%). Out of 30 cases, 18(69.2%) women had LSCS, 6(23.07%) had vaginal delivery,2(7.7%) had vaccum & 3(10.3%) had abortion. Out of 26 deliveries 2(7.7%) were IUFD, 6(23.07%) Preterm, 7(26.9%) IUGR. Total there were 9(37.5%) NICU admissions. Conclusion: Prognosis of pregnancy with heart disease has improved but management of it is still a challenge for obstetricians. Pre-conceptional counseling plays an important role by benefiting women with severe heart disease and thus help in reducing maternal morbidity and mortality. Keywords:  cardiac disease, maternal outcome, fetal outcome

scholarly journals Cardiovascular diseases during pregnancy and delivery

2013 ◽  
Vol 66 (11-12) ◽  
pp. 507-513
Author(s):  
Zoran Stajic ◽  
Zdravko Mijailovic ◽  
Mirjana Bogavac ◽  
Biljana Lazovic ◽  
Maja Stojanovic
Keyword(s):  
Cardiovascular Disease ◽  
Cardiovascular Diseases ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Cardiovascular System ◽  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Circulating Blood Volume ◽  
Maternal Morbidity And Mortality ◽  
In Pregnancy

Introduction. Nowadays, cardiovascular diseases are the leading cause of maternal morbidity and mortality in the current obstetric practice. Physiologically Adapted Mechanisms of the Cardiovascular System in Pregnancy. It is normal that during pregnancy some physiological adaptive changes of the cardiovascular system occur and they may contribute to the deterioration of the clinical cardiac status of a patient with preexisting or acquired cardiovascular disease. The most prominent adaptive mechanisms include the increase of circulating blood volume, decrease of peripheral vascular resistance and decrease of plasma colloid-oncotic pressure. Most Frequent Diseases of the Cardiovascular System in Pregnancy. Due to these changes, pregnant women are prone to tachycardia, palpitations and peripheral edema. Maternal counseling is obligatory for each pregnant woman in order to decrease the maternal morbidity and mortality. The most important predictors of maternal mortality for pregnant women with cardiovascular diseases are severity of pulmonary hypertension, hemodynamic significance of valvular lesion, cyanosis and functional status in heart failure. Cardiovascular diseases in pregnant women may be congenital or acquired. The most frequent congenital cardiac diseases are atrial and ventricular septal defects as well as persistent ductus arteriosus. These diseases are mainly diagnosed and corrected before the pregnancy, or left untreated if hemodynamically insignificant. The most frequent acquired cardiovascular diseases during pregnancy include arrhythmias, ischemic heart disease, rheumatic mitral stenosis and insufficiency, arterial hypertension and aortic dissection. Conclusion. In all cases of pregnancy associated with cardiovascular diseases, early recognition of cardiovascular disease is crucial, as well as correct diagnosis and referral to a tertiary centre equipped for a multidisciplinary approach of specialists experienced in high-risk pregnancies and deliveries in order to prevent maternal mortality.

scholarly journals 639 Co-occuring opioid and methamphetamine use disorder and severe maternal morbidity and mortality in Utah

2021 ◽  
Vol 224 (2) ◽  
pp. S401-S402
Author(s):  
Marcela Smid ◽  
Amanda A. Allshouse ◽  
Kristine Campbell ◽  
Michelle P. Debbink ◽  
Adam G. Gordon ◽  
...  
Keyword(s):  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Severe Maternal Morbidity ◽  
Methamphetamine Use ◽  
Maternal Morbidity And Mortality ◽  
Methamphetamine Use Disorder

scholarly journals Severe Maternal Morbidity and Mortality Among Indigenous Women in the United States

2020 ◽  
Vol 135 (2) ◽  
pp. 294-300 ◽  
Author(s):  
Katy B. Kozhimannil ◽  
Julia D. Interrante ◽  
Alena N. Tofte ◽  
Lindsay K. Admon
Keyword(s):  
United States ◽  
Maternal Morbidity ◽  
The United States ◽  
Indigenous Women ◽  
Morbidity And Mortality ◽  
Severe Maternal Morbidity ◽  
Maternal Morbidity And Mortality

112: An international collaboration for the prevention of severe maternal morbidity and mortality

2015 ◽  
Vol 212 (1) ◽  
pp. S73-S74
Author(s):  
Steve Rad ◽  
Godfrey Mugyenyi ◽  
Gabriel Ganyaglo ◽  
Paul Sobolewski ◽  
Nathaniel Sugiyama ◽  
...  
Keyword(s):  
International Collaboration ◽  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Severe Maternal Morbidity ◽  
Maternal Morbidity And Mortality

scholarly journals Maternal morbidity and mortality : an iceberg phenomenon

2021 ◽  
Author(s):  
S. Leitao ◽  
E. Manning ◽  
R. A. Greene ◽  
P. Corcoran ◽  
Bridgette Byrne ◽  
...  
Keyword(s):  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Maternal Morbidity And Mortality
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