scholarly journals Mediastinal mature teratoma in an adolescent: a rare case presentation

2019 ◽  
Vol 6 (11) ◽  
pp. 4177
Author(s):  
Divyang Dave ◽  
Nipun Bansal ◽  
Hardik Astik ◽  
Varun Joshi ◽  
Ojas Patel
Keyword(s):  
Germ Cell ◽  
Rare Case ◽  
Mature Teratoma ◽  
Germ Cell Tumour ◽  
Anterior Mediastinum ◽  
Government Medical College ◽  
Common Site ◽  
Case Presentation ◽  
Medical College ◽  
Low Incidence

Teratomas are the most common germ cell tumours composed of two or more germ layers. Mediastinum is the most common site of extragonadal germ cell tumour. Teratomas are relatively rare of all tumours in mediastinum. Here, we report a rare case of an adolescent who presented with chest pain and breathlessness. CT scan showed a large, well-defined lesion with internal fat density, calcifications, cystic and solid components arising from anterior mediastinum. He was successfully operated and treated at New Civil Hospital Surat attached to Government Medical College Surat. The purpose of this case report is to bring in light to the mediastinal mature teratomas in adolescents as they have very low incidence rate.

scholarly journals CT features of mature teratoma in the mediastinum of two young adults—a report of two cases

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Naqibullah Foladi ◽  
Farhad Farzam ◽  
Najibullah Rahil ◽  
Mer Mahmood Shah Hoshang
Keyword(s):  
Germ Cell ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Anterior Mediastinum ◽  
Good Prognosis ◽  
Chest Ct ◽  
Case Presentation ◽  
Superior Mediastinum ◽  
Chest Ct Scan ◽  
Ct Features

Abstract Background Germ cell tumors prefer gonadal regions, but they can be expected in extragonadal sites such as the anterior mediastinum, which is the commonly involved region after gonads. Amongst germ cell tumors, teratomas are the rarer subtypes which develop in the anterior mediastinum. Case presentation The authors present two adult patients, a male and a female, both complaining of chronic chest pain and cough. Chest CT scans were performed revealing characteristic CT features of mature teratomas in the anterior mediastinum which were extending to the superior mediastinum in both patients. Conclusion Germ cell tumors are involving the mediastinum; however, amongst all germ cell tumors, teratoma is the least common type arising in the mediastinum, and a chest CT scan considered the imaging investigation of choice. Surgery is the best option and patients may have a very good prognosis.

scholarly journals A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Sammy G. Nakhla ◽  
Srinath Sundararajan
Keyword(s):  
Germ Cell ◽  
Rare Case ◽  
Germ Cell Tumors ◽  
Anterior Mediastinum ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Elderly Adult ◽  
Children And Young Adults ◽  
Extragonadal Germ Cell Tumors ◽  
Mediastinal Germ Cell Tumors

Mediastinal germ cell tumors are extragonadal germ cell tumors (EGGCTs) commonly seen in children and young adults. They are more common in men. Clinically they are classified as teratomas, seminomas, and nonseminomatous germ cell tumors. Primary mediastinal yolk sac neoplasm is an extremely rare tumor. We present here a very rare case of primary yolk sac tumor of the anterior mediastinum in a 73-year-old male. Mediastinal germ cell tumors have a worse prognosis than gonadal germ cell tumors. Chemotherapy followed by adjuvant surgery improves overall response in EGGCTs. However, comorbidities can render treatment with chemotherapy and surgery challenging in elderly patients.

scholarly journals Sympathetic ophthalmitis: A rare case presentation

2016 ◽  
Vol 4 (2) ◽  
pp. 65-67
Author(s):  
Paras Panjiyar ◽  
Natwar Singh Parihar
Keyword(s):  
Surgical Procedure ◽  
Rare Case ◽  
Eye Injury ◽  
Case Presentation ◽  
Granulomatous Uveitis ◽  
Medical College ◽  
Sympathetic Ophthalmitis ◽  
Perforating Eye Injury

Sympathetic Ophthalmitis is a rare, granulomatous uveitis occurring after perforating eye injury or ocular surgical procedure to one eye. The pathophysiologyis not clearly understood. We report a rare case of sympathetic ophthalmitis that presented to us in our hospital.Journal of Kathmandu Medical College, Vol. 4, No. 2, Issue 12, Apr.-Jun., 2015 page: 65-67

scholarly journals Choroidal Metastasis Secondary to Testicular Mature Teratoma: A Case Report

2021 ◽  
pp. 1-6
Author(s):  
Bashar M. Bata ◽  
Sachin M. Salvi
Keyword(s):  
Germ Cell ◽  
Adjuvant Radiotherapy ◽  
Rare Case ◽  
Mature Teratoma ◽  
Germ Cell Tumours ◽  
Macular Disease ◽  
Choroidal Metastasis ◽  
Testicular Germ Cell ◽  
Testicular Germ Cell Tumours ◽  
Normal Visual Acuity

We report a case of a choroidal metastasis secondary to testicular mature teratoma, a subtype of non-seminoma germ cell tumours, in a young adult male. The choroidal metastasis was treated successfully with bleomycin, etoposide, and cisplatin chemotherapy without the need for adjuvant radiotherapy. This represents a rare case of mature teratoma metastasizing to the choroid and one of very few reported testicular germ cell tumours to achieve normal or near normal visual acuity with chemotherapy alone despite severe macular disease at presentation.

scholarly journals A Study on Histopathological Pattern of Ovarian Tumours in Chittagong Medical College Hospital

2020 ◽  
Vol 19 (2) ◽  
pp. 13-17
Author(s):  
Mahmuda Begum ◽  
Md Mukhlesur Rahman ◽  
Mahmuda Jahan ◽  
Zillur Rahman ◽  
Shahanara Chowdhury
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumour ◽  
Malignant Tumour ◽  
Ovarian Tumour ◽  
Medical College Hospital ◽  
Cell Tumour ◽  
College Hospital ◽  
Medical College ◽  
Ovarian Tumours ◽  
Serous Cyst

Background: Ovarian tumours may either be asymptomatic, found on the routine ultrasound examination or symptoms may be vague till the patient has an acute emergency like torsion or rupture of a benign cyst. The worst is late presentation of malignant ovarian tumour. There is marked variation in the presentation of the tumour as well as in histological types. This study was under taken to analyse modes of presentation and various histopathological patterns of ovarian tumour. Materials and Methods: A total of 69 cases were selected consecutively. The age range was 13-70 years. This study was carried out in the Department of Pathology, Chittagong Medical College and Department of Gynaecology and obstetrics, Chittagong Medical College Hospital during the period from July 2013 to June 2014. The specimens of ovarian tumours were subjected to histopathological examination in the histopathology section. Results : Out of 69 cases, 54(78.3%) were benign and 15(21.7%) were malignant tumour. There was no borderline malignancy in our study. The commonest histological pattern in this study was surface epithelial tumour 49(70.6%) including both benign and malignant tumour followed by germ cell tumour 6(8.7%). The commonest benign tumour was serous cyst cyst adenoma 23(33.4) and malignant tumour was serous cyst adenocarcinoma 5(7.2%). Conclusion : Surface epithelial tumours are the commonest variety of ovarian tumour followed by germ cell tumour. The histological type of ovarian tumour correlates with the prognosis of the tumour. Chatt Maa Shi Hosp Med Coll J; Vol.19 (2); July 2020; Page 13-17

Testicular non-seminomatous germ cell tumour presenting as a neck lump: a diagnostic and therapeutic challenge

2020 ◽  
Vol 1 (1) ◽  
pp. 19-23
Author(s):  
Mohammad Hasan ◽  
◽  
Leanne Duff ◽  
Sara Katharine Drever ◽  
Andrea Chapman ◽  
...  
Keyword(s):  
Germ Cell ◽  
Mature Teratoma ◽  
Germ Cell Tumour ◽  
Needle Aspiration ◽  
Good Prognosis ◽  
Cell Tumour ◽  
Retroperitoneal Lymphadenectomy ◽  
Young Males ◽  
Left Neck ◽  
Neck Lump

Testicular tumours are one of the most prevalent cancers in young males. Teratoma is one type of testicular tumour, which carries a good prognosis if treated appropriately. We describe a case of a 37 year old man, diagnosed with testicular non-seminomatous germ cell tumour in 2005. He underwent left orchidectomy and radical chemotherapy with Bleomycin, Etoposide and Cisplatin. He had involved retroperitoneal lymph nodes at the time of diagnosis and underwent retroperitoneal lymphadenectomy in 2007. He made a good recovery but presented with a left neck lump in 2009, the appearance of which suggested differentiated teratoma on fine needle aspiration cytology. The neck lump was excised without any complications and histology confirmed the mass to be mature teratoma with no undifferentiated elements. He has remained disease free since then and remains under oncological surveillance, in keeping with current protocols.

scholarly journals Prevalence of ovarian tumours among ovarian mass lesions in Gajra Raja Medical College, Gwalior, India

2017 ◽  
Vol 6 (9) ◽  
pp. 3907
Author(s):  
Jyoti Bindal ◽  
Sangeeta Bankey
Keyword(s):  
Germ Cell ◽  
Ovarian Tumor ◽  
Germ Cell Tumour ◽  
Early Period ◽  
Ovarian Tumour ◽  
Cell Tumour ◽  
Medical College ◽  
Presenting Symptoms ◽  
Ovarian Tumours ◽  
Epithelial Tumour

Background: Ovarian tumor is one of the most common gynecological tumors seen in female although there are different types of ovarian tumor but epithelial ovarian cancer is the fifth most common cause of cancer death in women. It is often called the “silent killer” because the disease is not often detected until it reaches an advance stage.Methods: This observational study conducted on 130 patients from February 2015 to March 2017 in the Department of Obstetrics and Gynaecology in Gajra Raja Medical College, Gwalior. Clinical details of the patients included age, gynaecological and obstetric history, presenting symptoms, and surgery details. Histopathological reporting was done at our Pathology department.Results: Out of total 130 patients with ovarian tumours studied 49.2% were > 60 years of age group, most of them were nullipara (53.8%), 54.6% with ovarian tumours presented after one-year development of symptoms. most of the symptoms were vague and nonspecific. Benign tumours were the most prevalent (79.2%), 19.2% were malignant tumours and 1.5% were borderline. Histological pattern of distribution of ovarian tumour shows that most of ovarian tumour were surface epithelial tumour (72 patients) followed by germ cell tumour (58 patients). Age wise distribution of study population showed that most of the surface epithelial tumour were more common in 3rd to 5th decade while most of germ cell tumour were more frequent in 2nd and 3rd decade.Conclusions: For better prognosis and patient survival, early detection and treatment is mandatory, which may reduce mortality. There is need to increase awareness of population. Abdominal and pelvic bimanual examination should be carried out in every patient presenting with gynecological problem. Appropriate investigations in post-menopausal women in early period to diagnose the disease at an early stage.

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