scholarly journals Correlation of Fine Needle Aspiration Cytology with Histopathological Findings in the Diagnosis of Thyroid Swellings – A One Year Study in a Tertiary Care Hospital, Hyderabad

2021 ◽  
Vol 8 (18) ◽  
pp. 1246-1251
Author(s):  
Keerthana Muppidi ◽  
Vidya Kedarisetti ◽  
Kanya Kumari Mahankali
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Nodular Goitre ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

BACKGROUND Most of the thyroid swellings are non-neoplastic and with normal thyroid hormone. So, it doesn't require any surgical excision, even though the thyroid swelling is an indication for surgical excision. The present study was done to evaluate the accuracy of fine needle aspiration cytology (FNAC) for the thyroid swellings and correlate it with the histopathological findings. METHODS This is a prospective study. A total of 47 cases were studied. Fine needle aspiration cytology was done, slides were made and studied. Histopathological examination of the corresponding 47 cases was also done and correlated with FNAC findings. Sensitivity, specificity and accuracy were calculated. RESULTS Age of the patients varied from 20 - 69 yrs. Most of them were in the age group of 30 - 39 years and 50 - 59 years. The ratio of male to female was 1:4.9. Swelling of the neck was the most common presentation in most of the patients. On FNAC 33 (70.2 %) cases were diagnosed as colloid nodular goitre, 04 (8.5 %) as autoimmune thyroiditis, 08 (17.0 %) as follicular neoplasm, 01 (2.1 %) as suspicious of malignancy, 01 (2.1 %) as papillary carcinoma. On histopathological examination 25 (53.2 %) cases were diagnosed as colloid nodular goitre, 01 (2.1 %) as fibrous thyroiditis, 01 (2.1 %) as Graves’ disease, 07 (14.9 %) as Hashimoto’s’ thyroiditis, 06 (12.8 %) as follicular adenoma, 01 (2.1 %) as follicular carcinoma, 04 (8.5 %) as papillary carcinoma and 02 (4.2 %) as NIFTP (noninvasive follicular thyroid neoplasm with papillary like nuclear features). The overall sensitivity was 69.2 %, specificity was 97.0 % and accuracy was 89.3 %. CONCLUSIONS FNAC is a minimally invasive, highly accurate and cost-effective procedure. FNAC helps the clinician to diagnose malignant lesions with confidence. It has high rates of specificity and accuracy but comparatively has less sensitivity. However, it is very important for the management of patients with thyroid swelling. KEYWORDS Fine Needle Aspiration, Prospective Study, Sensitivity, Specificity, Thyroid Swelling

scholarly journals Comparative study of fine needle aspiration cytology and histopathology of thyroid swellings in tertiary health centre

2021 ◽  
Vol 8 (1) ◽  
pp. 53
Author(s):  
Gangadhara K. S. ◽  
Chaitanya Vadva ◽  
Sridhara S.
Keyword(s):  
Fine Needle Aspiration ◽  
Predictive Value ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Health Centre ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

<p><strong>Background: </strong>Thyroid swelling being the most common presentation in ENT clinical practice, a prospective study was done to assess the role of Fine needle aspiration cytology in diagnosing the nature of thyroid swellings and comparing its results with histopathological examination findings.<strong></strong></p><p><strong>Methods: </strong>This is a prospective institutional based study comparing cytology and corresponding histopathology findings reported in 60 cases of thyroid swelling. The statistical analysis included sensitivity, specificity, positive predictive value, negative predictive value and accuracy in thyroid swelling.<strong></strong></p><p><strong>Results: </strong>Out of 60 cases, FNAC showed 93.3% and 6.6% of benign and malignant cases respectively whereas HPE showed 86.7% and 13.3% of benign and malignant cases respectively. On FNAC-HPE correlation using HPE as standard reference the diagnostic accuracy of present study is 91.66%.<strong></strong></p><p><strong>Conclusions: </strong>It was observed that FNAC is a reliable tool, safe and accurate method in evaluating thyroid swelling thus having great influences in treatment decision. Thus FNAC is the investigation of choice in thyroid swellings with excellent patient compliance, simple, safe and cost effective.<strong></strong></p>

scholarly journals Study of Correlation of Preoperative Fine Needle Aspiration Cytology with Histopathological Examination in Thyroid Swellings

2017 ◽  
Vol 7 (1) ◽  
pp. 16-19
Author(s):  
Sri Lekha Bodepudi ◽  
KASSN Kalyan ◽  
Ramarao Peddi
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Histopathological Analysis ◽  
Histopathological Diagnosis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Thyroid Swelling ◽  
Needle Aspiration Cytology

ABSTRACT Introduction Though fine needle aspiration cytology (FNAC) for thyroid is acclaimed as a gold standard before going for intervention, there are some limitations with respect to tissue availability, technique, skill of performer, etc. So, a cross-sectional study was conducted to determine the accuracy of FNAC in diagnosis of thyroid swelling and to assess the correlation between preoperative cytopathological diagnosis and postoperative histopathological diagnosis. Materials and methods Data collected from records in the time period of 3 years, i.e., from August 2012 to August 2015, were evaluated and analyzed. Results A total number of 93 cases were included in the study of which majority were females with frequency of 84.94%, most of the incidence of thyroid swellings occur in the age group of 40 to 50 years. Overall mismatch between histopathological examination and FNAC was 43 out of 93 and of which 7 were major and 36 were minor mismatch. Sensitivity of patients having malignancy with positive FNAC is 82.35% from the study and specificity of patients with nonmalignant thyroid disease and positive cytology is 95.18%. Conclusion It was observed that FNAC is a reliable, safe, and accurate method as a first line of evaluation in thyroid swelling before the surgery. Fine needle aspiration cytology is more sensitive in detecting thyroid gland malignancy but still correlation is always necessary and therefore, histopathological analysis still remains essential for final diagnosis. How to cite this article Bodepudi SL, Kalyan KASSN, Peddi R. Study of Correlation of Preoperative Fine Needle Aspiration Cytology with Histopathological Examination in Thyroid Swellings. Int J Phonosurg Laryngol 2017;7(1):16-19.

scholarly journals Cysticercosis: Hooked by a Hooklet on Fine Needle Aspiration Cytology—A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-2 ◽  
Author(s):  
Manav Sawhney ◽  
Shubhra Agarwal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Bladder Wall ◽  
Clinical Manifestations ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Muscle Involvement ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Cysticercosis is a systemic parasitic disease caused by the larval form of cestodeT. solium. It has a worldwide distribution and is potentially harmful with variable clinical manifestations. The patient most commonly presents with subcutaneous and muscle involvement in the form of nodular lesions. The other most commonly involved sites include eye, brain, bladder wall, and heart. Cysticercosis can be diagnosed on serology, and radiologically but confirmatory diagnosis is based on histopathological examination of the involved tissue biopsy specimen. Fine needle aspiration cytology is a useful low-cost outpatient procedure tool for preoperative diagnosis of cysticercosis and is absolutely essential for diagnosis of the parasitic lesions in a peripheral hospital, one like ours.

scholarly journals Fine needle aspiration cytology in feline skeletal muscle as a diagnostic tool for extramedullary plasmacytoma

2017 ◽  
Vol 69 (3) ◽  
pp. 587-592
Author(s):  
D.B. Martins ◽  
C.K. Rossato ◽  
S.L. Silva ◽  
S.S.N. Almeida ◽  
L.S. Ribeiro
Keyword(s):  
Skeletal Muscle ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Extramedullary Plasmacytoma ◽  
Feline Leukemia Virus ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

ABSTRACT Extramedullary noncutaneous plasmacytoma (ENP) is a myeloproliferative disorder of plasma cells that rarely affects cats. This paper describes an ENP case revealed by fine needle aspiration cytology (FNAC) of the mass in the skeletal muscle of an 8-month-old, male, mixed breed cat, which had a nodule in the left hind limb. The rapid immunoassay test confirmed the presence of feline leukemia virus (FeLV). The animal necropsy macroscopically showed the nodule came from the semimembranosus muscle. Histopathological examination ratified the cytological findings. Thus, this paper alerts to the existence of plasmacytoma located in the skeletal muscle of feline species. FNAC is a quick and efficient method for diagnosis of ENP.

scholarly journals Fine-needle aspiration cytology of pilomatrixoma: A short series of three cases

CytoJournal ◽  
2014 ◽  
Vol 11 ◽  
pp. 30 ◽  
Author(s):  
Jitendra Singh Nigam ◽  
Savitri Singh
Keyword(s):  
Head And Neck ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Neck Region ◽  
Middle Finger ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Pilomatrixoma (PMX) (pilomatricoma, calcifying epithelioma of Malherbe) is a benign tumor with differentiation toward the hair matrix cells and is common in head and neck region. It is most commonly seen in the first two decades of life and presents as a subcutaneous, small, asymptomatic firm solitary nodule. Fine-needle aspiration cytology (FNAC) has been described as an important preoperative diagnostic investigation though on cytology the diagnosis of PMX is sometimes difficult and misdiagnosed. We describe two patients with gradually increasing asymptomatic swelling on pinna and middle finger. FNAC was done and a diagnosis of PMX was given, further confirmed by histopathological examination. The present cases highlight the importance of FNAC in considering PMX as differential diagnosis of dermal or subcutaneous nodules in locations other than head and neck. Cytopathologists who play an important role in the preliminary diagnosis should keep in mind the variability of the cellular composition of these types of lesions to avoid misdiagnosis.

scholarly journals Correlation of ultrasonography and fine needle aspiration cytology for diagnosis of malignancy in thyroid lesions: a study of 100 cases

2021 ◽  
Author(s):  
E. Pavan Kumar ◽  
S. Namratha ◽  
Siva Subba Rao Pakanati ◽  
Uma Pokala
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Prospective Clinical Study ◽  
Specific Information ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

<p class="abstract"><strong>Background:</strong> The majority (90%) of thyroid lesions are benign as malignancy occurs only 1 in 10 thyroid nodules. The purpose of ultrasonography (USG) and fine needle aspiration cytology (FNAC) is to pick the patients having malignancy for surgical intervention. The objective of present study is to correlate ultrasonography findings with FNAC for diagnosis of malignancy in thyroid lesions by relating these findings to histopathological examination (HPE) reports.</p><p class="abstract"><strong>Methods:</strong> A prospective clinical study carried out from September 2019 to February 2021, in the Department of Ear Nose and Throat (ENT), Mamata Medical College, Khammam, in patients with clinical evidence of thyroid swelling. Ultrasound and FNAC were done in all cases and HPE were done in cases where surgeries were performed at our institution. The results were analysed.  </p><p class="abstract"><strong>Results:</strong> According to USG,<strong> </strong>out of 100 cases 93 cases were found to be of benign thyroid swellings, 4 cases were suspected malignant and 3 cases were found malignant. According to FNAC, out of 100 cases 97 cases were benign and 3 cases were confirmed to be malignant. Two cases which were found to be malignant on both USG and FNAC were confirmed as malignant according to HPE report.</p><p class="abstract"><strong>Conclusions:</strong> USG is a sensitive modality in the assessment of thyroid swellings with good accuracy. FNAC also provides the most direct and specific information about thyroid lesions. It is suggested that USG followed by FNAC provides better diagnosis in thyroid lesions.</p>

scholarly journals A large malignant oncocytoma of parotid gland: a case report

2020 ◽  
Vol 6 (12) ◽  
pp. 2310
Author(s):  
Nidhi S. Mohan ◽  
Sunita S. Vernekar ◽  
Mohammed M. Abus Samee ◽  
Manjunath D.
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Fine Needle Aspiration ◽  
Facial Palsy ◽  
Fine Needle Aspiration Cytology ◽  
Histopathological Examination ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

<p class="abstract">Malignant oncocytoma is an extremely rare neoplasm of the salivary gland accounting for 0.5% of epithelial salivary gland malignancies and 0.18% of epithelial salivary gland tumors. We report a case of malignant oncocytoma of left parotid gland in a 61-year old female patient. Patient presented with a 6-year history of painless swelling in the left parotid region. Fine needle aspiration cytology of the swelling was suggestive of pleomorphic adenoma. A computed tomography scan performed did not reveal any features suggestive of malignancy. Patient underwent left superficial parotidectomy. However, histopathological examination of the specimen turned out to be malignant oncocytoma. Malignant oncocytoma of salivary glands have rare incidence and may have similar morphologic features with other neoplasms. Despite the tumor being large and malignant in this case, there was no facial palsy preoperatively. As histopathology is often diagnostic, the possibility of malignancy always must be kept in mind preoperatively even when there is no facial palsy or fine needle aspiration cytology not showing up malignancy.</p>

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