scholarly journals LABORATORY-CLINICAL SUBSTANTIATION OF ATRAVMATICITY OF USING INDIVIDUAL HEALING ABUTMENT OF THE AUTHOR'S DESIGN

2019 ◽  
Vol 15 (3) ◽  
pp. 96-102
Author(s):  
Петрос Нерсесян ◽  
Petros Nersesyan ◽  
Сергей Жолудев ◽  
Sergey Zholudev ◽  
Владимир Базарный ◽  
...  
Keyword(s):  
Tooth Loss ◽  
Comparison Group ◽  
Control Group ◽  
Laboratory Studies ◽  
Clinical Observations ◽  
Dental Implantation ◽  
Before And After ◽  
Connective Tissue Matrix ◽  
Tissue Matrix

Subject. To improve the effectiveness of prosthetics for tooth loss, an abutment is proposed, which is used both as an artificial crown and a gum former, which is especially important for prosthetics in the frontal group of teeth. An analysis was made of the local content of matrix metalloproteinases (MMP) 8 and 9 and their tissue inhibitor (TIMP) and buccal cytology in patients before and after dental implantation surgery using the author's technique and the traditional protocol. Objective ― to evaluate the effectiveness and non-invasiveness of using the author’s abutment design under immediate loading by evaluating oral homeostasis and the level of cell proliferation. Methodology. Three groups of patients were examined: the main of 25 patients from 30 to 60 years old, who used the original technique, comparisons - 40 patients of the same age, where prosthetics and implantation were performed according to the traditional two-stage protocol and a control group of 40 somatically preserved patients of the same age, which do not require dental prosthetics. In all groups, MPP 8, 9, TIMP were studied, and the buccal cytology was also evaluated. Results. The pathogenetic role of disorders of the connective tissue matrix in the development of early complications of dental implantation was revealed. Findings: Laboratory studies and clinical observations of patients of the main group and the comparison group indicate the effectiveness and non-invasiveness of the original methods of prosthetics on implants using an individual abutment with a gingiva shaper.

Carvacrol attenuates amikacin-induced nephrotoxicity in the rat

2021 ◽  
Author(s):  
Atta Mohammad Dost ◽  
Mehmet Gunata ◽  
Onural Ozhan ◽  
Azibe Yildiz ◽  
Nigar Vardi ◽  
...  
Keyword(s):  
Inflammatory Cell ◽  
Kidney Tissue ◽  
Control Group ◽  
Histopathological Changes ◽  
Sprague Dawley ◽  
Tissue Samples ◽  
Sprague Dawley Rats ◽  
Before And After ◽  
Per Oral

Abstract Amikacin (AK) is frequently used in the treatment of gram-negative and some gram-positive infections. However, its use is limited due to nephrotoxicity due to the increase in reactive oxygen radicals. The aim of this study was to investigate the role of carvacrol (CAR) against AK-induced nephrotoxicity in rats. Thirty-two Sprague Dawley rats were randomly divided into four groups as control (Vehicle), AK (400 mg/kg), CAR + AK (80 mg/kg CAR + 400 mg/kg AK), and AK + CAR (400 mg/kg AK + 80 mg/kg CAR) groups. AK and CAR were administered via intramuscular and per-oral for 7 days, respectively. Blood and kidney tissue samples were taken at the end of the experiment. Renal function and histopathological changes were compared, and the relevant parameters of oxidative stress and inflammation were detected. Histopathological findings (necrotic changes and dilatation and inflammatory cell infiltration) significantly increased in the AK group compared to the control group. Also, the rats in the AK group lost weight significantly. It was found that CAR treatment before and after AK significantly improved nephrotoxicity histopathologically (p < 0.05). However, this improvement was not detected biochemically. These results show that CAR treatment before and after AK improves nephrotoxicity in the histopathological level.

Learning Transfer from Flexion to Extension Movements: Importance of the Final Position

Motor Control ◽  
1998 ◽  
Vol 2 (3) ◽  
pp. 221-227 ◽  
Author(s):  
Dusko B. Ilic ◽  
Dragan M. Mirkov ◽  
Slobodan Jaric
Keyword(s):  
Elbow Flexion ◽  
Control Group ◽  
Final Position ◽  
Variable Error ◽  
Before And After ◽  
Movement Distance ◽  
Level Of Significance ◽  
Experimental Group ◽  
Flexion And Extension

Nine subjects (experimental group) were tested on rapid elbow flexion and extension movements performed in the same final position, before and after extensive practice of the movements. Nine additional subjects (control group) were also tested, but without any practice between the tests. Comparison of the pretest and posttest results suggested that the experimental group decreased their variable error (i.e., standard deviation of the final movement position) in both practiced (elbow flexion) and nonpracticed (elbow extension) movements. The control group, however, did not improve in either of tested movements. The experimental group demonstrated lower variable error in the nonpracticed elbow extensions than the control group, while the same difference for practiced elbow flexion movements was slightly below the level of significance. The results support the importance of the final position in programming of rapid, self-terminated movements; however, they do not rule out the role of other kinetic and kinematic variables (such as movement distance).

scholarly journals The role of zinc sulphate and omega 3 in improving of albumin level on pulmonary tuberculosis patients in Paru Hospital Surabaya 2015

2017 ◽  
Vol 4 (1) ◽  
pp. 51
Author(s):  
Fara Disa Durry ◽  
Bambang Wirjatmadi
Keyword(s):  
Immune System ◽  
Treatment Group ◽  
Pulmonary Tuberculosis ◽  
Zinc Sulphate ◽  
Albumin Level ◽  
Control Group ◽  
Omega 3 ◽  
Tuberculosis Patients ◽  
Before And After

The epidemiology of Tuberculosis (TB) showed that TB is a disease which is associated with malnutrition. Malnutrition and lacking of certain essential nutrients required by immune system might cause immune function deficiency resulting higher susceptibility to bacterial and viral infections. There is positive correlation between immune system and high nutrient contents, such as Vitamin C, zinc, and antioxidants that brings good effect on infections, including Tuberculosis. One of the efforts conducted to help promoting improving albumin level on pulmonary tuberculosis patients is through zinc and sulphate provision followed by Omega-3 supplementation. This study was conducted in 2015 aimed to analyze the role of Zinc Sulphate Omega-3 provision in improving albumin level on pulmonary tuberculosis patients in Paru Hospital, Surabaya.This study applied randomized study design using Pre-test and Post-test Control group design on patients suffering pulmonary tuberculosis. This study was conducted by administering Zinc Sulphate and Omega-3 on treatment group and placebo on the control group. The samples of this study consisted of 20 pulmonary tuberculosis patients divided into two groups: treatment group and control group. Each group consisted of 10 patients. Statistical analysis was conducted using paired T-test and independent t-test. The results is There were significant differences in albumin level (p = 0.001) in the treatment group before and after supplementation Zinc Sulphate And Omega 3. While in the control group between before and after supplementation Zinc Sulphate And Omega 3 showed no significant differences in body weight (p = 0.224). The conclusions is Zinc Sulphate and Omega 3 plays a role in increasing albumin level respondents. There are significant differences on albumin level before and after supplementation Zinc Sulphate And Omega 3.

scholarly journals The role of interleukins 17, 23 and antibodies to the thyroid-stimulating hormone receptor in the pathogenesis of endocrine ophthalmopathy

2018 ◽  
Vol 14 (2) ◽  
pp. 72-80
Author(s):  
Svetlana V. Charinzeva ◽  
Elizaveta S. Taskina
Keyword(s):  
Hormone Receptor ◽  
Comparison Group ◽  
Study Groups ◽  
Thyroid Stimulating Hormone ◽  
Control Group ◽  
Clinical Activity ◽  
Clinical Group ◽  
Endocrine Ophthalmopathy ◽  
Stimulating Hormone

Background. Endocrine ophthalmopathy (EOP) is an autoimmune orbit disease characterized by soft retrobulbar tissues damage. The level of antibodies to the thyroid-stimulating hormone receptor (TSHRAbs) is considered as a laboratory marker of EOP activity. Interleukins 17 (IL-17) and 23 (IL-23) play an important role in the pathogenesis of some autoimmune diseases and directly correlate with clinical activity. At present, there is an open question about the role of these cytokines in EOP and their relationship with TSHRAbs. Aims. To assess pathogenetic role of IL-17, IL-23 and TSHRAbs in patients with EOP. Materials and methods. The study included 50 people (100 eyes) at the age of 43 [35; 50] years. Three study groups were formed: 32 patients with moderate severity of EOP (clinical group), 18 patients with thyroid pathology without EOP (comparison group) and 15 healthy subjects (control group). All groups were comparable in age and sex. The diagnosis was verified clinically, laboratory and instrumentally. A comprehensive ophthalmologic examination and blood sampling were performed to determine the concentrations of IL-17, IL-23 and TSHRAbs. Statistical processing of the data was carried out in the program “Statistica 10.0”, StatSoft, Inc. Results. An increase in the level of TSHRAbs was observed in all phases of EOP activity in comparison with both comparison group and control (p < 0.05). But in the active phase TSHRAbs level reached the maximum values in 100% of patients. An increase in the IL-17 concentration in 5,3 times was found in the active EOP in comparison with the control group (p < 0.05). Concentration of TSHRAbs and IL-17 in blood serum directly correlates with EOP activity (p < 0.001). After carrying out pulse therapy with glucocorticosteroids, the consentration of IL-17 decreased almost to zero. There were no significant differences in the level of IL-23 in the groups (p = 0.56). Conclusions. Determination of TSHRAbs and IL-17 levels in serum can be used as a laboratory diagnostic marker of EOP activity.  

scholarly journals Effect of Stimulation to Grow Baby in Bukittinggi City in 2018

2018 ◽  
Vol 3 (1) ◽  
pp. 115
Author(s):  
Wiwit Fetrisia ◽  
Aisyah Elyanti ◽  
Yantri Maputra
Keyword(s):  
Growth And Development ◽  
Health Workers ◽  
Intervention Group ◽  
Infant Growth ◽  
Control Group ◽  
Initial Stage ◽  
Before And After ◽  
Quasi Experimental ◽  
Role Of Parents

The initial stage of a human's life in infancy is considered important because at this time the foundations of personality are laid down which will give color when they grow up. The role of parents is very necessary in providing early stimulation. Stimulation is stimulation that comes from the baby's outer environment. The baby health service coverage in 2014 in Bukittinggi was 88.4%, lower than Padang city as much as 90.6%. It is known that the number of infants aged 0-1 years in Padang city amounted to 3,498 people, while in Bukittinggi city only 629 people. Supposedly with a small number of infants achieving early detection of infant growth and development is better than the number of babies in a larger city. The design of this study was a quasi-experimental design with two group pretest-posttest with the control group to identify the effect of stimulation on infant growth and development before and after the intervention, which was carried out from November 2017 - August 2018, in the environmental health center of Bukittinggi City Health Office. The population is infants with ages 0 - 6 months, and the number of samples taken is 46 people. The results of the study carried out with the Wolcoxon test, obtained there were differences in development before and after the intervention was given to the intervention group p = 0,000, there was a development difference in the control group p = 0.014, there were differences in growth before and after the intervention p = 0.000, there was no difference growth in the control group p = 0.083. It can be concluded that stimulation plays a role in preventing delays in growth and development in infants 0-6 months. From this study health workers can socialize about how to stimulate babies to mothers for early prevention of growth and development disorders in infants.

scholarly journals Agonistic behaviour and biogenic amines in shore crabs Carcinus maenas

2000 ◽  
Vol 203 (3) ◽  
pp. 537-545 ◽  
Author(s):  
L.U. Sneddon ◽  
A.C. Taylor ◽  
F.A. Huntingford ◽  
D.G. Watson
Keyword(s):  
Mass Spectrometry ◽  
Carcinus Maenas ◽  
Gas Chromatography Mass Spectrometry ◽  
Control Group ◽  
Agonistic Behaviour ◽  
Blood Samples ◽  
Dopamine Concentration ◽  
Before And After ◽  
Shore Crabs

To investigate the role of certain neurohormones in agonistic behaviour, fights were staged between pairs of size-matched male shore crabs Carcinus maenas, and blood samples were taken immediately after the contests had been resolved. Samples were also taken from these crabs at rest (before and after fighting) and after walking on a treadmill. A control group of crabs also had samples taken on each experimental day. Concentrations of tyramine, dopamine, octopamine, serotonin (5-HT) and norepinephrine were determined in each blood sample using a gas chromatography/mass spectrometry (GC-MS) system. Norepinephrine was not detectable in any of the samples, but the standards were recovered. Tyramine values were not significantly different between the control group and the fought group, so tyramine does not appear to be important in agonistic behaviour. A comparison between the control and fought groups shows that fighting had an effect on the concentrations of octopamine, dopamine and 5-HT, but exercise only had an effect on octopamine levels, which showed a reduction from resting values in both winners and losers. Resting and post-fight concentrations of octopamine, dopamine and 5-HT were higher in winners than in losers. 5-HT concentration increased in the blood of fought crabs from resting values, whereas dopamine concentration decreased. In winners, octopamine concentrations decreased from resting values, but in losers octopamine levels increased from resting concentrations. The escalatory behaviour or intensity of fighting performed by winners and losers was related to dopamine levels but not to those of octopamine or 5-HT. Therefore, there appears to be a link between relative concentrations of these three amines (dopamine, octopamine and 5-HT) and fighting ability; the effects are not simply a result of activity. The better competitors have higher concentrations of these three amines at rest and after fighting.

Role of Pleural Mesothelial Cells in the Production of the Submesothelial Connective Tissue Matrix of Lung

1984 ◽  
Vol 130 (2) ◽  
pp. 267-274 ◽  
Author(s):  
Stephen I. Rennard ◽  
Marie-Claude Jaurand ◽  
Jean Bignon ◽  
Oichi Kawanami ◽  
Victor J. Ferrans ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Mesothelial Cells ◽  
Pleural Mesothelial Cells ◽  
Connective Tissue Matrix ◽  
Tissue Matrix

A Pilot Study on the Effect of Rapport on the Task Performance of an Elderly Confused Population

1988 ◽  
Vol 55 (5) ◽  
pp. 255-258 ◽  
Author(s):  
Linda Porszt-Miron ◽  
Majka Florian ◽  
Jean Burton
Keyword(s):  
Task Performance ◽  
Effective Interaction ◽  
Control Group ◽  
Helping Professions ◽  
Group Leaders ◽  
Control Subjects ◽  
Clinical Observations ◽  
Before And After ◽  
Experimental Subjects ◽  
Positive Effect

Rapport has been viewed traditionally by the helping professions as a prerequisite to effective interaction between therapist and patient. Clinical observations indicate that confused elderly residents of a Home for the Aged have the capacity to establish warm personal relationships with their therapists and caregivers. In order to determine if this apparent rapport has a positive effect on task performance, six confused subjects were assigned either to an experimental or control group. They were administered the Picture Identification Task before and after receiving a program designed to establish rapport with their respective leaders. All testing was done by the experimental group leaders. Thus the experimental subjects had rapport with the administrators, while the control subjects did not. The data indicated that experimental subjects decreased their inappropriate behaviours, were able to respond quicker, and made better use of nonverbal test cues at posttest. Control subjects did not demonstrate these changes. It was concluded that rapport can facilitate some task behaviours despite cognitive impairment.

Imagining the Possibilities: The Effects of a Possible Selves Intervention on Self-Regulatory Efficacy and Exercise Behavior

2010 ◽  
Vol 32 (4) ◽  
pp. 537-554 ◽  
Author(s):  
Elisa C. Murru ◽  
Kathleen A. Martin Ginis
Keyword(s):  
Goal Setting ◽  
Self Efficacy ◽  
Possible Selves ◽  
Exercise Behavior ◽  
Control Group ◽  
Regulatory Processes ◽  
Before And After ◽  
Activity Measures ◽  
Intervention Condition

This experiment examined the effects of a possible selves intervention on self-regulatory efficacy and exercise behavior among 19 men and 61 women (M age = 21.43 years, SD = 3.28) who reported exercising fewer than 3 times per week. Participants were randomly assigned to a control condition, a hoped-for possible selves intervention condition, or a feared possible selves intervention condition. The hoped-for and feared possible selves interventions required participants to imagine themselves in the future as either healthy, regular exercisers or as unhealthy, inactive individuals, respectively. Participants in the control condition completed a quiz about physical activity. Measures of self-regulatory efficacy (scheduling, planning, goal setting, and barrier self-efficacy) were taken immediately before and after the intervention. Participants who received either possible selves intervention reported greater exercise behavior 4 weeks and 8 weeks postintervention than participants in the control group. Planning self-efficacy partially mediated the effects of the possible selves intervention on exercise behavior over the first 4 weeks of the study. These findings highlight the effectiveness of possible selves interventions for increasing exercise behavior and the role of self-regulatory processes for explaining such effects.

Aldosterone in panhypopitutarism: dynamic studies and therapeutic effects in Sheehan's syndrome

1986 ◽  
Vol 112 (3) ◽  
pp. 329-335 ◽  
Author(s):  
Fawzi Bakiri ◽  
Anne M. Riondel ◽  
Moulai Benmiloud ◽  
Michel B. Vallotton
Keyword(s):  
Thyroid Hormone ◽  
Control Group ◽  
Minor Role ◽  
Therapeutic Effects ◽  
Aldosterone Secretion ◽  
Before And After ◽  
Basal Plasma ◽  
Stimulation Tests ◽  
A Minor

Abstract. To appreciate the aldosterone secretion status in panhypopituitarism, the steroid response to stimulation was studied in a homogeneous group of 20 female patients presenting with global hypopituitarism. Specific effects of glucocorticoid and thyroid hormone deficiencies were also assessed by studying the same patients before and after cortisol (F) and cortisol plus thyroid hormone (F + T) substitution. The patients were submitted to two stimulation tests before and after each treatment: the orthostasis test (O-T) and the furosemide test (Furo-T). The results obtained in the 3 situations were compared, each patient serving as her own control. Comparison was also established with the results obtained in healthy women serving as control group. Basal plasma aldosterone levels in the untreated patients were not significantly different from those of the control group (5.43 ± 0.51 vs 7.16 ±0.80 ng/100 ml, mean ± sem). They were significantly lower after F (3.91 ± 0.42) and F + T substitution (3.31 ± 0.23) than those of untreated patients and controls. Response to both stimulations was blunted in the untreated patients (O-T: 14.10 ± 2.81; Furo-T: 9.78 ± 1.35) as compared to the control group (O-T: 26.46 ± 4.67; Furo-T: 23.96 ± 3.30). F treatment did not improve the response to either tests, (O-T: 11.42 ± 2.55; Furo-T: 10.32 ± 1.23). F + T treatment normalized the orthostasis response (20.83 ± 3.59) and increased the response to furosemide which remained, however, lower (15.28 ± 1.83) than in the control group. These results are in favour of a minor role of the pituitary in the regulation of aldosterone secretion. They emphasize the role of thyroid hormones which may act partly directly, partly through their effect on renin secretion.

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