scholarly journals Antichlamydia IgG Antibody in Adult Asthmatics in Al-Najaf

2020 ◽  
Author(s):  
Iman Jabbar Kadhim Al-Ghizzi ◽  
Israa Khudhair Abbas ◽  
Suaad Muhammed Hassan Rasheed ◽  
Falah Abdulhasan Deli
Keyword(s):  
Chlamydia Pneumoniae ◽  
Inverse Correlation ◽  
Control Group ◽  
Igg Antibody ◽  
Asthmatic Patients ◽  
Test Parameters ◽  
Medical City ◽  
Asthma And Allergy ◽  
The Difference ◽  
And Gender

Infection is presumed to have a rule in the promotion of asthma exacerbations, and in deterioration of the course of the disease, Chlamydia pneumoniae (C. pneumoniae) is claimed to be a possible cause for these two issues. To assess the positivity and the titer of C. pneumoniae IgG antibodies in relation to the state of asthma and its severity. 61 asthmatic patients aged 15-85 years (mean of 47.10±14.887), and 29 apparently healthy, nonasthmatic age and gender-matched volunteers (control group) were assessed as at Asthma and Allergy Clinic in Al-Sader Medical City in AL-Najaf province, Chlamydia Pneumoniae IgG ELISA Kit was used for the detection of IgG antibody to C. Pneumoniae in human serum to detect chronic infection, and Spirometric test was done, and the best results for FEV1 and PEFR were taken. IgG antichlamydial antibodies were positive in 21 (34.4%) of patients compared to 4 (13.8%) of controls, and the difference was significant with OR=3.281, the seropositivity in acute exacerbation was more than in stable asthmatic, 43.8% vs. 24.1% (P=0.029), seropositivity was nonsignificantly more in moderate and severe asthma as compared with mild asthma, a significant inverse correlation between IgG titer and pulmonary function test parameters (FEV1, PEFR) was observed as the FEV1 & PEFR values decrease with increase IgG titer. Chronic C. pneumoniae infection is common in adult asthmatics and correlated with exacerbations & increased severity and disturbed lung function.

The role of Chlamydia pneumoniae in severe acute tonsillitis

1994 ◽  
Vol 108 (2) ◽  
pp. 135-137 ◽  
Author(s):  
S. W. Hone ◽  
J. Moore ◽  
J. Fenton ◽  
P. K. Gormley ◽  
R. Hone
Keyword(s):  
Chlamydia Pneumoniae ◽  
Antibody Test ◽  
Control Group ◽  
Direct Immunofluorescence ◽  
Serological Evidence ◽  
Igg Antibody ◽  
Acute Tonsillitis ◽  
Recent Infection ◽  
College Hospital

AbstractChlamydia pneumoniae has been implicated as a cause of tonsillitis and pharyngitis, but the incidence has varied from one to 19 per cent in various studies. We investigated 51 patients admitted to University College Hospital, Galway, with severe tonsillitis. Throat swabs were examined for evidence of Chlamydia pneumoniae using a direct monoclonal antibody test. Blood was taken for serology from 45 patients. A further specimen was taken at six weeks. A control group of 32 blood bank sera was used. Mean hospital stay was three days (one to eight). Five patients (10 per cent) were monospot positive. Chlamydia pneumoniae was identified by direct immunofluorescence on a tonsillar swab from one patient who did not seroconvert. IgG antibody was identified in 13 cases (29 per cent) and in seven of the control group (22 per cent). No serological evidence of recent infection was found. Chlamydia pneumoniae was not found to be a cause of severe acute tonsillitis in our study group.

Seroprevalence of Chlamydia pneumoniae infections in otolaryngeal diseases

1992 ◽  
Vol 106 (3) ◽  
pp. 208-210 ◽  
Author(s):  
Kazuhiro Hashiguchi ◽  
Hiroshi Ogawa ◽  
Yukumasa Kazuyama
Keyword(s):  
Otitis Media ◽  
Chlamydia Pneumoniae ◽  
Control Group ◽  
Past Infection ◽  
The Third ◽  
Acute Infections ◽  
Common Pathogen ◽  
The Difference

AbstractWe studied the seroprevalence of antibodies to Chlamydia pneumoniae, the third species of chlamydia, in patients with acute infections in otolaryngeal sites. The patients were divided into five diagnostic groups, i.e. sinusitis, otitis media, tonsillitis, laryngitis and bronchitis group. Antibodies were measured by the microimmunofluorescent method. Antibodies confirming past infection with C. pneumoniae were found 46.2 per cent of the patients in the diagnostic groups and 44.7 per cent of the subjects in the control group. The difference between these two groups was not statistically significant. Acute or recent antibodies were detected in 10.5 per cent (2/19) of these patients with sinusitis, 19.2 per cent (10/52) of those with tonsillitis, 23.5 per cent (8/34) of those with otitis media, 18.2 percent (6/33) of those with laryngitis and 22.8 percent (13/57) of those with bronchitis, whereas only one member of the control group had acute antibodies. These data suggested that C. pneumoniae is an important and common pathogen of otolaryngeal disease.

Important Role of B2-Glycoprotien in Females with Recurrence Abortion

2018 ◽  
Vol 9 (01) ◽  
Author(s):  
Ahmed Abbas Hasan ◽  
Radhia Hussain Fadel ◽  
Saeed Hilal Khudhair ◽  
Doaa Hashim Jawad
Keyword(s):  
Pearson Correlation ◽  
Mean Value ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
P Value ◽  
Recurrent Abortion ◽  
Significant Difference ◽  
Medical City ◽  
And Gender ◽  
Age Range

Recurrent abortion consider as one of the most common problem in world. There are different causes associated with recurrent abortion, these may be occur due to complication of microorganism infection or associated with immunological disturbance like abortion caused by Anti-phospholipid syndrome, or associated with SLE. The anti-b2glucoprotien antibodies have a role in abortion. In this study, we wish to determine whether there is a relationship between the levels of these anti-b2glucoprotien antibodies and abortion. Thirty females patients with spontaneous abortion (10 of them with Antiphospholipid syndrome,10 of them with systemic lupus erthymatosus and final 10 with toxoplasmosis with ages ranged between (20-46) where taken from (Al-Hussein Medical City/Kerbala). Control group consisted of 20 healthy people who were free from history of abortion who matched in age and gender with patients. B2gp(IgMandIgG) EASIA Kit, generic assay) and was studied using the enzyme-linked immunosorbent assay (ELISA) method. T-test and ANOVA and Pearson correlation used to analyze results by using SPSS version 24. P-value ≤ 0.05 was considered significant. The patients with age range blow 30 years show high percent(63.3%) among the other groups .most of the patients have high percent of 3 times abortion were reported in all different groups .The mean value of anti-B2gP-I IgG (45.354) show highly a significant difference results in aborted patients with APS and significant difference in patients with SLE when compared with controls groups. the Anti-B2gPI IgM not give statistically significant difference when camper to health cases. we conclude that the Anti-B2GPI IgG levels were increased significantly in aborted females with APS and SLE .

scholarly journals Anti-S. typhi Vi IgG levels in children with and without typhoid vaccinations

2014 ◽  
Vol 54 (5) ◽  
pp. 284
Author(s):  
Sriandayani Sriandayani ◽  
Tonny H. Rampengan ◽  
Hesti Lestari ◽  
Novie Rampengan
Keyword(s):  
Typhoid Fever ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Igg Antibody ◽  
Protective Antibody ◽  
Significant Difference ◽  
Antibody Titers ◽  
The Mean ◽  
And Gender ◽  
Antibody Levels

Background Typhoid fever is endemic to Indonesia, with an annual incidence of 13/10,000 people. Vaccination has been shown to be an effective method to prevent typhoid fever. Of several vaccine types, the polysaccharide Vi vaccine is the most commonly used typhoid vaccine in developing countries. Results of previous studies remain inconclusive on the necessity of revaccination every 3 years.Objective To compare the mean serum anrioody titers of anti-S. typhi Vi IgG and the proportion of children with protective antibody levels between children with and without typhoid Vi vaccination.Methods We conducted a cross-secrional study at Tuminring District, 11anado from June to September 2012. Data was analyzed using independent T-test and Fisher's test. Serum anti-S. typhi Vi IgG levels were measured by enzyme-linked immunosorbent assay (ELISA) method.Results Seventy-six subjects were divided into two groups: 38 children who had received the typhoid Vi vaccination more than 3 years prior to this study and 38 children who never had typhoid vaccinations as a control group. No statistically significant difference in age and gender was found between the two groups. The mean serum anti-Vi IgG level was 0.55 ug/mL (SD 0.58; 95%CI 0.36 to 0.74) in the vaccinated group, significantly higher than that of the control group [0.31 ug/mL (SD 0.12); 950/£1 0.17 to 0.44; P􀂥0.0381. The proportion of children with protective antiNi antioody level was higher in the vaccinated group (23.7%) than in the control group  (10.5%), howevet; this difference was not statistically significant (P=0.128).Conclusion The mean serum anti-S. typhi Vi IgG antibody level in children who had been vaccinated more than 3 years prior to the study is higher than in children who had never received typhoid vaccinations. Nevertheless, the mean antibody titers are generally non-protective in ooth groups. Also, the proportion of children with protective antibody levels is not significantly different between the two groups.

scholarly journals CORRELATION STUDY BETWEEN THREE DIFFERENT GENES EXPRESSION AND CHRONIC MYELOID LEUKEMIA IN IRAQ

2021 ◽  
Vol 52 (3) ◽  
pp. 611-619
Author(s):  
Aljoubory & Altaee
Keyword(s):  
Gene Expression ◽  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Correlation Study ◽  
Control Group ◽  
Age And Gender ◽  
Patient Groups ◽  
The Difference ◽  
And Gender ◽  
And Control

The following study was conducted to investigate the correlation between the expression of three different genes (NOB1, DDX47, CD101 (with the occurrence and development of chronic myeloid leukemia (CML) in Iraq. The difference in the expression of these genes between patients and healthy controls was studied. Moreover the correlation of age and gender with CML occurrence and comparing with control was also examined. Results showed significant increases in mean of gene expression level (ΔCt) of patient groups for all genes compared to the corresponding ΔCt means in control group, also the gene expression folding (2-∆∆Ct) reflect significant differences in the expression of these genes and CD101, mRNA showed the highest level in CML patients which reached to (3.44), while NOB1 and DDX47 recorded (2.90 and 1.08) respectively. On the other hand no significant differences were recorded according to age and gender between CML patients and control, CML disease could affect any age and both male and female.

scholarly journals The Content of Essential and Toxic Metals in the Hair of Children with Autistic Spectrum Disorders

2021 ◽  
Keyword(s):  
Toxic Metals ◽  
Toxic Metal ◽  
Study Groups ◽  
Autism Spectrum ◽  
Control Group ◽  
Study Group ◽  
Hair Samples ◽  
The Difference ◽  
And Gender ◽  
Cr Concentration

The aim of this study was to assess the possible relationship between the content of essential and toxic metals in the hair samples with the etiology of autism spectrum disorder (ASD) in children from Bosnia and Herzegovina. Taking into account the age and gender of the child, in the study and control group, the samples were divided into three subgroups (1-5 years; 6-9 years; 10-14 years). Altered profiles of the values of the Cu, Fe, Mn, Zn, Cd, Co, Cr, Ni, Pb in the study group were observed in comparison with the control group children with typical neuromotor development. Higher values of toxic metal concentrations (Co, Ni, Cd, Pb) were found in boys, compared to the girls in the study group. The content of Pb in the study group was higher in all three ages compared to their controls, with the difference being especially pronounced in the age group 1-5 years (6.64 mg/kg; 1.89 mg/kg). A strong correlation between the content of Pb and Cd (0.93) was confirmed. Lower values of Cr concentration and higher of Ni, Cu and Fe were recorded in the study group. Statistically significant differences (p<0.05) were found in Zn concentrations (6-9 years; 10 -14 years) between the control and study groups. The findings help highlight the role of heavy metals as environmental factors in the etiology of ASD.

scholarly journals The Effect of Experiential Learning Viewed From Gender Differences Perspective toward Physics Learning Outcome

2019 ◽  
Vol 7 (2) ◽  
pp. 221-234
Author(s):  
Nurfadilah Nurfadilah
Keyword(s):  
Experiential Learning ◽  
Learning Outcome ◽  
Female Students ◽  
Control Group ◽  
Control Group Design ◽  
Physics Learning ◽  
Physics Students ◽  
Post Test ◽  
The Difference ◽  
And Gender

This research was a quasi-eksperiment by using nonequivalent control group design and factorial design 2x2. It was conducted in class X-1 and X-2 of senior high school 1 of Takkalalla Wajo and aimed to: (1) analyse the difference of physics learning outcome between students who where taught with experiential learning and the ones who where taught conventionally; (2) analyse the difference of physics learning outcome between male students who where taught with experiential learning and the ones who where taught conventionally; (3) analyse the difference of physics learning outcome between female students who where taught with experiential learning and the ones who where taught conventionally; (4) analyse the interaction between learning models (experiential and conventional laerning) and gender (male and female students) toward the achievement of students physics learning outcome. The collection of data carried out before the use of experiential learning in class experiments and conventional in the control class in order to determine whether different initial knowledge of students (pre-test), and the results for the experimental class to learn physiscs of controls didn’t differ significantly. Thus the hypothesis test conducted after the second execution after the learning by giving the final test (post-test) was used parametric test. The results of hypotheses testing that used two-way variance analysis with SPSS 16 showed that (1) there was difference of physiscs learning outcomes significantly between students with experiential learning and conventionally; (2) there are differences in learning outcomes were not significant among physics students with experiential learning and conventionally on male students; (3) there are differences in learning outcome were not significant among physics students with eksperiential learning and conventionally on female students; (4) there was no interaction between learning models (experiential and conventional laerning) and gender (male and female students) toward the achievement of students physics learning outcome.Keywords: experience, gender, learning outcomePenelitian ini merupakan penelitian eksperimen semu menggunakan desain penelitian nonequivalent control group design dan rancangan faktorial 2×2 yang dilaksanakan di kelas X-1 dan X-2 SMAN 1 Takkalalla Kabupaten Wajo dengan tujuan untuk; (1)menganalisis perbedaan hasil belajar Fisika siswa antara yang diajar melalui pembelajaran berdasarkan pengalaman dan secara konvensional, (2)menganalisis perbedaan hasil belajar Fisika siswa antara yang diajar melalui pembelajaran berdasarkan pengalaman dan secara konvensional untuk laki-laki, (3)menganalisis perbedaan hasil belajar Fisika siswa antara yang diajar melalui pembelajaran berdasarkan pengalaman dan secara konvensional untuk perempuan, dan (4)menganalisis interaksi antara pembelajaran (berdasarkan pengalaman dan secara konvensional) dengan gender (siswa laki-laki dan perempuan) terhadap pencapian hasil belajar Fisika siswa. Pengumpulan data dilaksanakan sebelum digunakan pembelajaran berdasarkan pengalaman dikelas eksperimen dan secara konvensional di kelas kontrol dengan tujuan untuk mengetahui berbeda tidaknya pengetahuan awal siswa (pre-test), dan diperoleh hasil belajar fisika untuk kelas eksperimen dan kontrol yang tidak berbeda secara signifikan. Dengan demikian uji hipotesis yang dilakukan setelah pelaksanaan kedua pembelajaran usai maka pemberian tes akhir (post test) digunakan uji parametrik. Hasil pengujian hipotesis yang dilakukan dengan analisis varians dua jalur dengan SPSS 16 yang menunjukkan bahwa (1)terdapat perbedaan hasil belajar fisika yang signifikan antara siswa dengan pembelajaran berdasarkan pengalaman dan secara konvensional, (2)terdapat perbedaan hasil belajar fisika yang tidak signifikan antara siswa dengan pembelajaran berdasarkan pengalaman dan secara konvensional pada siswa laki-laki, (3)terdapat perbedaan hasil belajar fisika yang tidak signifikan antara siswa dengan pembelajaran berdasarkan pengalaman dan secara konvensional pada siswa perempuan, dan (4)tidak terdapat interaksi antara pembelajaran (berdasarkan pengalaman dan secara konvensional) dengan gender (laki-laki dan perempuan) terhadap hasil belajar fisika siswa.Kata kunci: pengalaman, gender, hasil belajar

scholarly journals Serum 25-hydroxy vitamin D in asthmatic children and its relation to disease severity

2019 ◽  
Vol 6 (2) ◽  
pp. 454
Author(s):  
Ihab Hafez El Sawy ◽  
Passant Al-Said Moaz ◽  
Ghada Mohamed Farouk El Deriny ◽  
Mohamed Sami Abd El Moniem El Kholy
Keyword(s):  
Vitamin D ◽  
Severe Asthma ◽  
Control Group ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Moderate Asthma ◽  
Asthmatic Children ◽  
Asthmatic Patients ◽  
Vitamin D Levels ◽  
The Difference

Background: Asthma is a chronic immunological disorder of the lungs. Vitamin D has several effects on the innate and adaptive immune systems. Little is known about vitamin D level and its impact on severity of asthma in children. This study aimed to determine vitamin D levels in asthmatics versus control children; studying the relation if any between these levels and asthma severity.Methods: This cross-sectional study was conducted on 60 asthmatic children and 20 apparently healthy children as controls. Asthma patients were divided into 3 groups (mild, moderate, severe; 20 each). Asthma severity was based on GINA criteria. Vitamin D level was measured to all study group.Results: The difference between the mean values of vitamin D level in control and asthmatic patients was statistically significant (p<0.001). This difference between control group and each asthma subgroup and between asthma subgroups versus each other were statistically significant being highest in control and lowest in patients with severe asthma (p<0.001). Differences in vitamin D status in control and all asthmatic patients were statistically significant (p<0.001). The difference between control group and each asthma subgroup according to vitamin D status were statistically significant (p<0.001). Concerning asthma subgroups the difference in vitamin D status between severe versus mild and moderate asthma were statistically significant (p<0.001), while between mild and moderate asthma it was not.Conclusions: Significantly lower vitamin D level in asthmatic children compared to controls and a differential decrease in vitamin D levels in asthmatic children being lowest in severe asthma was confirmed.

scholarly journals Chlamydia pneumoniaeAntibodies and C-Reactive Protein Levels in Patients with Abdominal Aortic Aneurysms

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
M. A. Sharif ◽  
D. A. McDowell ◽  
S. A. Badger
Keyword(s):  
Chlamydia Pneumoniae ◽  
Aortic Aneurysms ◽  
Control Group ◽  
C Reactive Protein ◽  
Serum Samples ◽  
Igg Antibody ◽  
Protein Levels ◽  
Reactive Protein ◽  
Abdominal Aortic ◽  
Antibody Titres

Introduction. The study aim was to assess the relationship between the presence of antibodies toChlamydia pneumoniaeand abdominal aortic aneurysm (AAA) incidence.Patients and Methods. Consecutive AAA patients and AAA-free controls were recruited prospectively. Serum samples from both groups were examined to determine Immunoglobulin (Ig) A and IgG titres againstChlamydia pneumoniaeby ELISA and C-reactive protein (CRP) concentrations. Results were expressed as mean (SD) or median (IQR) and compared usingχ2and Mann-WhitneyUtests. APvalue of <0.05 was considered statistically significant.Results. Each study group (AAA/nAAA) comprised 250 patients. 196 (78.7%) AAA patients had positive IgA antichlamydial antibody titres, compared to 181 (72.4%) in the control group (P=0.008, OR 2.0, 95% CI 1.2–3.5). However, positive IgG antibody titres were similar (191 versus 203;P=0.222, OR 0.7, 95% CI 0.4–1.3). Average CRP concentrations were higher in AAA individuals. IgA or IgG antibody titres were not related to CRP concentrations.Conclusions. These results demonstrated that the frequent incidence ofChlamydia pneumoniaeantibodies within the general population makes it difficult to relate its presence to AAA development, despite the high IgA antibody titres. In addition, raised CRP concentrations in AAA patients are not related to the presence of antichlamydial antibodies.

scholarly journals Enhancing metacognitive skills of students with different gender using simas eric learning model at state senior high school 6 Malang

Biosfer ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 48-57
Author(s):  
Ericka Darmawan ◽  
Yuli Brasilita ◽  
Siti Zubaidah ◽  
Murni Saptasari
Keyword(s):  
High School ◽  
Learning Model ◽  
Senior High School ◽  
Control Group ◽  
Metacognitive Skills ◽  
Control Group Design ◽  
Group Design ◽  
Quasi Experimental ◽  
The Difference ◽  
And Gender

The aim of the research is to know the influence of Simas eric (Skimming, Mind mapping, Questioning, Exploring, Writing, Communicating) cooperative learning model on difference gender on the XIth grade student’s metacognition skills of Biology in State Senior High School 6 Malang. This research was quasi-experimental with non-equivalent pretest posttest control group design. The sample used was XI MIA 1 and XI MIA 2 class of the State Senior High School 6 Malang. The data had been collected by observation of students’s metacognition skills. The data analysed by Anacova techniques showed that Simas eric learning model on difference gender effect on the XIth grade student’s metacognition skills in State Senior High School 6 Malang. The result of the research showed that Simas eric learning model influenced the XIth grade student’s metacognition skills, the difference gender and interaction of learning model and gender did not influence student’s metacognition skills.

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