Prevalence and Risk Factors of Asthma among People aged 45 and Older in Mainland China: A Cross-sectional Study from CHARLS in 2018
Abstract Background: Asthma is one of the most prevalent chronic respiratory disease worldwide. The survey aims to describe the updated prevalence and risk factors of asthma among individuals aged 45 and older in mainland China. Methods: The data for this study come from the fourth wave of China Health and Retirement Longitudinal Study (CHARLS) conducted by the National School of Development of Peking University in 2018. CHARLS is a nationally representative survey targeting populations aged 45 and over from 28 provinces/cities in mainland China. A representative sample of 19816 participants were recruited for the study using a multi-stage stratified sampling method. The prevalence of asthma was described across different characteristics. The potentially risk factors were examined by multivariable logistic regressions. Results: A total of 18504 participants (8759 men and 9745 women) were eligible for the final data analysis. The estimated prevalence of asthma among Chinese people age≥ 45 years in 2018 was 2.16% (95%CI 1.96-2.38). The prevalence of asthma significantly differs according to race (P=0.002), with an overall rate of 2.06% (95% CI 1.86-2.29) in Han and 3.28% (95%CI 2.47-4.34) in minorities. Furthermore, the minorities (OR=1.54 [95% CI 1.114-2.122], P=0.009), elderly people (60-69 years group: OR= 2.65 [95% CI 1.230-5.702], P=0.013; ≥ 70 years group: OR=3.38 [95% CI 1.741-8.036], P=0.001), middle-school education and below (middle-school education: OR=1.91[95%CI: 0.678-1.193], P=0.009; primary education: OR=2.59 [95% CI 0.675- 1.199], P< 0.001; literate: OR=2.60 [95% Cl 0.480- 0.928; illiterate: OR=2.89 [95% CI 0.220-0.572]), smokers (OR=1.36 [95% CI 1.109-1.677], P=0.003), North (OR=1.51[95% CI 1.02-2.078], P=0.01) or Northwest China residence (OR=1.70 [95% CI 1.170-2.472], P=0.005) were associated with prevalent asthma. Conclusions: Asthma is prevalent but underappreciated among middle-aged and elderly people in China. A number of risk factors were identified. These results can help to formulate correct prevention and treatment measures for asthma.