scholarly journals Suicidality and associated social, demographic and clinical factors in Thai patients with acutely treated depressive disorder: a cross-sectional study

2020 ◽  
Author(s):  
Mayteewat Chiddaycha ◽  
Peeraphon Lueboonthavatchai
Keyword(s):  
Social Support ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Family Relationships ◽  
Suicide Risk ◽  
Previous History ◽  
Clinical Factors ◽  
Poor Family ◽  
History Of ◽  
Social Demographic

Abstract Background Some depressed people die by suicide although they are in treatment. The aims of this study were to examine the prevalence of suicidality and to identify the associated social, demographic and clinical factors in Thai patients with acutely treated depressive disorders.Patients and methods A sample of 178 in- and outpatients with depressive disorders who were treated within the six-month period of being diagnosed or of a recurrent episode were recruited from a tertiary hospital during November 2017 to April 2018. The associations between suicide risks assessed using the suicidality module of the Mini-International Neuropsychiatric Interview (MINI) and various factors including demographic data, depressive severity, interpersonal problems, social support, family relationships, and life stress events were analyzed by chi-square test. Logistic regression was used for identification of the potential predictors of moderate-to-high suicide risk.Results Most of the subjects were single (80.9%), female (68%), and in early adulthood (mean age 28.9, SD 11.2). The prevalence of suicidal ideation, suicide attempt within one month, and previous history of suicide attempt during lifetime were 62.4%, 35.4% and 41%, respectively. The prevalence of suicidality (76.4%) and moderate-to-high suicide risk (48.4%) were high. The factors associated with moderate-to-high suicide risk were lower age, no religion, unemployment, history of substance use within one year, moderate-to-severe level of depression, being an in-patient, short duration of treatment, receiving benzodiazepines, having interpersonal role disputes, having interpersonal deficits, low social support, poor family relationships and functioning, and high severity level of health stress events. Potential predictors of moderate-to-high suicide risk were moderate-to-severe levels of depression, poor family relationships and functioning, age of 20 or lower, being an in-patient, and receiving benzodiazepines.Conclusion The prevalence of suicidality in patients with acutely treated depressive disorder was found to be high. Depressive severity and social factors such as poor family relationships were highly associated with suicide risk. Knowledge of these factors may raise awareness of suicide prevention during the course of treatment of depression.

Suicide attempts preceding completed suicide

1998 ◽  
Vol 173 (6) ◽  
pp. 531-535 ◽  
Author(s):  
Erkki T. Isometsä ◽  
Jouko K. Lönnqvist
Keyword(s):  
Suicide Attempt ◽  
Suicide Prevention ◽  
Suicide Risk ◽  
Suicide Attempts ◽  
Early Recognition ◽  
Preventive Measure ◽  
Time Interval ◽  
Psychological Autopsy ◽  
Autopsy Study ◽  
History Of

BackgroundThis study investigated three questions with major implications for suicide prevention: the sensitivity of the history of previous suicide attempt(s) as an indicator of suicide risk, the time interval from a preceding suicide attempt to the fatal one, and switching of suicide methods by those eventually completing suicide.MethodThe lifetime history of suicide attempts and the methods the victims (n=1397) used were examined in a nationwide psychological autopsy study comprising all suicides in Finland within a 12-month research period in 1987–1988.ResultsOverall, 56% of suicide victims were found to have died at their first suicide attempt, more males (62%) than females (38%). In 19% of males and 39% of females the victim had made a non-fatal attempt during the final year. Of the victims with previous attempts, 82% had used at least two different methods in their suicide attempts (the fatal included).ConclusionsMost male and a substantial proportion of female suicides die in their first suicide attempt, a fact that necessitates early recognition of suicide risk, particularly among males. Recognition of periods of high suicide risk on the grounds of recent non-fatal suicide attempts is likely to be important for suicide prevention among females. Subjects completing suicide commonly switch from one suicide method to another, a finding that weakens but does not negate the credibility of restrictions on the availability of lethal methods as a preventive measure.

scholarly journals Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume

2008 ◽  
Vol 192 (4) ◽  
pp. 285-289 ◽  
Author(s):  
Keith A. Young ◽  
Willy L. Bonkale ◽  
Leigh A. Holcomb ◽  
Paul B. Hicks ◽  
Dwight C. German
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Genetic Variant ◽  
Antidepressant Treatment ◽  
Clinical Factors ◽  
Brain Disorder ◽  
Major Depressive ◽  
History Of ◽  
Post Traumatic ◽  
Psychiatric Conditions

BackgroundThe 5HTTLPR genetic variant of the serotonin transporter gene (SERT or 5-HTT), which is comprised of a short (SERT-s) and a long (SERT-l) allele, is associated with major depressive disorder and post-traumatic brain disorder.AimsThe present study sought to determine whether the total thalamus and major subregions are altered in size in major depressive disorder and in relation to the 5HTTLPR genotype.MethodWe investigated the influence of 5HTTLPR genotype, psychiatric diagnosis, suicide and other clinical factors on the volume of the entire post-mortem thalamus.ResultsMajor depressive disorder, SERT-ss genotype and suicide emerged as independent factors contributing to an enlargement of the total thalamus. The majority of the volume enlargement associated with the SERT-ss genotype occurred in the pulvinar, whereas enlargement associated with major depressive disorder occurred in the limbic nuclei and in other regions of the thalamus. A history of antidepressant treatment was associated with reduced thalamic volume.ConclusionsThe 5HTTLPR genetic variation may affect behaviour and psychiatric conditions, in part, by altering the anatomy of the thalamus.

History of suicide attempt and right superior temporal gyrus volume in youth with treatment-resistant major depressive disorder

2018 ◽  
Vol 239 ◽  
pp. 291-294 ◽  
Author(s):  
Quinn McLellan ◽  
T. Christopher Wilkes ◽  
Rose Swansburg ◽  
Natalia Jaworska ◽  
Lisa Marie Langevin ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Superior Temporal Gyrus ◽  
Treatment Resistant ◽  
Major Depressive ◽  
History Of

scholarly journals Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt

2014 ◽  
Vol 162 ◽  
pp. 34-38 ◽  
Author(s):  
Elizabeth D. Ballard ◽  
Dawn F. Ionescu ◽  
Jennifer L. Vande Voort ◽  
Elizabeth E. Slonena ◽  
Jose A. Franco-Chaves ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Major Depressive ◽  
Lifetime History ◽  
History Of ◽  
Fear Potentiated Startle

Lithium: poisonings and suicide prevention

2002 ◽  
Vol 17 (2) ◽  
pp. 92-95 ◽  
Author(s):  
F. Montagnon ◽  
S. Saïd ◽  
J.P. Lepine
Keyword(s):  
Suicide Attempt ◽  
Suicide Prevention ◽  
Lithium Treatment ◽  
Previous History ◽  
Careful Monitoring ◽  
Lithium Poisoning ◽  
History Of

SummaryThis study concerns 81 cases of lithium poisoning and shows that deliberate intoxications are prevalent during the first 3 years of lithium treatment as well as in cases with a previous history of suicide attempt. Therapeutic intoxications could generally be avoided by education concerning hygiene and diet and careful monitoring in cases of intercurrent diseases.

scholarly journals Prospective study of risk factors for suicidal behavior in individuals with anxiety disorders

2012 ◽  
Vol 43 (7) ◽  
pp. 1465-1474 ◽  
Author(s):  
L. A. Uebelacker ◽  
R. Weisberg ◽  
M. Millman ◽  
S. Yen ◽  
M. Keller
Keyword(s):  
Anxiety Disorder ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Anxiety Disorders ◽  
Prospective Study ◽  
Physical Health ◽  
Social Functioning ◽  
Suicide Attempts ◽  
Past History ◽  
History Of

BackgroundAnxiety disorders are very common and increase risk for suicide attempts. Little is known about predictors of increased risk specifically among individuals with anxiety disorders. The purpose of this study was to investigate whether specific anxiety disorders and other co-morbid psychiatric disorders, physical health, or work or social functioning increased the future likelihood of a suicide attempts among individuals with anxiety disorders.MethodIn this prospective study, 676 individuals with an anxiety disorder were followed for an average of 12 years.ResultsAs hypothesized, we found that post-traumatic stress disorder, major depressive disorder (MDD), intermittent depressive disorder (IDD), epilepsy, pain, and poor work and social functioning all predicted a shorter time to a suicide attempt in univariate analyses. In multivariate analyses, baseline MDD and IDD were independent predictors of time to suicide attempt, even when controlling for a past history of suicide attempt. No specific anxiety disorder was an independent predictor of time to attempt in this anxiety-disordered sample. Adding baseline physical health variables and social functioning did not improve the ability of the model to predict time to suicide attempt.ConclusionsMood disorders and past history of suicide attempts are the most powerful predictors of a future suicide attempt in this sample of individuals, all of whom have an anxiety disorder.

Drug Overdose-Induced Coma Blisters: Pathophysiology and Clinical and Forensic Diagnosis

2019 ◽  
Vol 11 (1) ◽  
pp. 21-25 ◽  
Author(s):  
Ricardo J. Dinis-Oliveira
Keyword(s):  
Soft Tissue ◽  
Suicide Attempt ◽  
Drug Overdose ◽  
State Of The Art ◽  
Previous History ◽  
Altered State ◽  
Soft Tissue Involvement ◽  
History Of ◽  
Altered State Of Consciousness ◽  
Limiting Condition

Background: Coma blisters or coma bullae are bullous lesions that have been associated with cases of drug overdose-induced coma. Previous history of suicide attempt by administering benzodiazepines, barbiturates, ethanol, antipsychotics, antidepressants or opioids have been particularly implicated. Patients may present also painful deep skin and soft tissue involvement, edema and functional impairment. The pathophysiology remains unknown and lesions are usually self-limited and typically resolve without scarring. Objective: This work aims to fully review the state of the art regarding the causes pathophysiology, diagnosis and treatment of drug overdose-induced coma blisters. Conclusion: Coma blisters are a benign, self-limiting condition that should be suspected in patients who develop pressure blisters several hours after an altered state of consciousness.

The association of suicide risk with negative life events and social support according to gender in Asian patients with major depressive disorder

2015 ◽  
Vol 228 (3) ◽  
pp. 277-282 ◽  
Author(s):  
Subin Park ◽  
Ahmad Hatim Sulaiman ◽  
Manit Srisurapanont ◽  
Sung-man Chang ◽  
Chia-Yih Liu ◽  
...  
Keyword(s):  
Social Support ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Life Events ◽  
Suicide Risk ◽  
Negative Life Events ◽  
Major Depressive ◽  
Asian Patients

Suicide Attempt History, Self-Esteem, and Suicide Risk in a Sample of 116 Depressed Voluntary Inpatients

2004 ◽  
Vol 95 (3_suppl) ◽  
pp. 1092-1094 ◽  
Author(s):  
Charles James Palmer
Keyword(s):  
Suicidal Ideation ◽  
Suicide Attempt ◽  
Suicide Risk ◽  
Suicide Ideation ◽  
Self Esteem ◽  
Significant Difference ◽  
History Of ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

116 consecutively admitted depressed inpatients were divided into three groups based on self-reported history of suicidal ideation and history of suicide attempt. Participants in Group 1 ( M age 34.0, SD = 14.0), 13 men and 24 women, reported no history of suicidal ideation or history of suicide attempt. Group 2 ( M age 34.0, SD = 8.6), 14 men and 25 women, reported having a history of suicidal ideation but no history of suicide attempt. Group 3 ( M age 34.0 yr., SD = 6.3), 14 men and 26 women, reported a history of suicidal ideation and at least one suicide attempt. Each participant completed the Suicide Risk Scale and the Self-esteem Scale. Analysis of variance with Tukey post hoc comparisons yielded a significant difference between Groups 1 and 2, between Groups 1 and 3, and between Groups 2 and 3 on the Suicide Risk Scale. There was a significant difference between Group 1 and Group 2 and between Group 1 and Group 3 on the Self-esteem Scale. These data indicated that suicide ideation and suicide attempt history significantly elevated suicide risk. Self-esteem was significantly decreased by suicide ideation and suicide attempt history.

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