Comparative Efficacy of N95, Surgical, Medical, and Non-Medical Facemasks in Protection of Respiratory Virus Infection: A Living Systematic Review and Network Meta-Analysis

2021 ◽  
Author(s):  
Min Seo Kim ◽  
Dawon Seong ◽  
Han Li ◽  
Seo Kyoung Chung ◽  
Youngjoo Park ◽  
...  
Keyword(s):  
Systematic Review ◽  
Virus Infection ◽  
Respiratory Virus ◽  
Meta Analysis ◽  
Comparative Efficacy ◽  
Respiratory Virus Infection

scholarly journals A meta-analysis reveals the effectiveness of probiotics and prebiotics against respiratory viral infection

2021 ◽  
Vol 41 (3) ◽  
Author(s):  
Fangyan Wang ◽  
Binhui Pan ◽  
Sheng Xu ◽  
Zhihua Xu ◽  
Tiaotiao Zhang ◽  
...  
Keyword(s):  
Virus Infection ◽  
Viral Infection ◽  
Respiratory Virus ◽  
Meta Analysis ◽  
Critical Role ◽  
Published Data ◽  
Respiratory Viral Infection ◽  
Tnf Α ◽  
Respiratory Virus Infection ◽  
Microbial Agents

Abstract Experimental experience suggests that microbial agents including probiotics and prebiotics (representative microbial agents) play a critical role in defending against respiratory virus infection. We aim to systematically examine these agents’ effect on respiratory viral infection and encourage research into clinical applications. An electronic literature search was conducted from published data with a combination of a microbial agents search component containing synonyms for microbial agents-related terms and a customized search component for respiratory virus infection. Hazard ratio (HR), risk ratio (RR) and standard deviation (SD) were employed as effect estimates. In 45 preclinical studies, the mortality rates decreased in the respiratory viral infection models that included prebiotics or prebiotics as interventions (HR: 0.70; 95% confidence interval (CI): 0.56–0.87; P=0.002). There was a significant decrease in viral load due to improved gut microbiota (SD: −1.22; 95% CI: −1.50 to −0.94; P<0.001). Concentrations of interferon (IFN)-α (SD: 1.05; 95% CI: 0.33–1.77; P=0.004), IFN-γ (SD: 0.83; 95% CI: 0.01–1.65; P=0.05) and interleukin (IL)-12 (SD: 2.42; 95% CI: 0.32–4.52; P=0.02), IL-1β (SD: 0.01; 95% CI: −0.37 to 0.40; P=0.94) increased, whereas those of TNF-α (SD: −0.58; 95% CI: −1.59 to 0.43; P=0.26) and IL-6 (SD: −0.59; 95% CI: −1.24 to 0.07; P=0.08) decreased. Six clinical studies had lower symptom scores (SD: −0.09; 95% CI: −0.44 to 0.26; P=0.61) and less incidence of infection (RR: 0.80; 95% CI: 0.64–1.01; P=0.06). Our research indicates that probiotics and prebiotics pose a defensive possibility on respiratory viral infection and may encourage the clinical application.

Characteristics of Respiratory Virus Infection During the Outbreak of 2019 Novel Coronavirus in Beijing

2020 ◽  
Author(s):  
Yan Li ◽  
Jiangshan Wang ◽  
Chunting Wang ◽  
Qiwen Yang ◽  
Yingchun Xu ◽  
...  
Keyword(s):  
Virus Infection ◽  
Respiratory Virus ◽  
Respiratory Virus Infection ◽  
Novel Coronavirus

scholarly journals Burden of hepatitis E virus infection in pregnancy and maternofoetal outcomes: a systematic review and meta-analysis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jean Joel Bigna ◽  
Abdou Fatawou Modiyinji ◽  
Jobert Richie Nansseu ◽  
Marie A. Amougou ◽  
Moise Nola ◽  
...  
Keyword(s):  
Systematic Review ◽  
Virus Infection ◽  
Hepatitis E Virus ◽  
Meta Analysis ◽  
Hepatitis E ◽  
In Pregnancy
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