scholarly journals Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Appraisal of the Available Clinical Evidence

2021 ◽  
Vol Volume 14 ◽  
pp. 1697-1724
Author(s):  
Hong Xiao ◽  
Dan Xu ◽  
Rui Mao ◽  
Minqin Xiao ◽  
Yang Fang ◽  
...  
Keyword(s):  
Clinical Evidence ◽  
Platelet Rich Plasma ◽  
Facial Rejuvenation ◽  
Systematic Appraisal

O uso de plasma rico em plaquetas e da fbrina rica em plaquetas injetável como terapias de rejuvenescimento facial

2020 ◽  
Vol 2 (5) ◽  
pp. 92-97
Author(s):  
Kely Pereira Borges ◽  
Sidmarcio Ziroldo
Keyword(s):  
Clinical Evidence ◽  
Platelet Rich Plasma ◽  
Therapeutic Option ◽  
Facial Rejuvenation ◽  
Production Costs ◽  
Allergic Reactions ◽  
Platelet Rich Fibrin ◽  
Aesthetic Practice ◽  
Qualitative Nature ◽  
The Aesthetic

The autologous concentrates of platelets and of growth factors have been used as a therapeutic option for facial rejuvenation, as they provide a biostimulation in the production of collagen. Platelet Rich-Plasma (PRP) and Injectable Platelet Rich-Fibrin (i-PRF) are safe options, without allergic reactions, and are autologous materials with reduced production costs, and with different protocols and presentations. The aim of this study was to highlight the benefits and specificities of the application of PRP and i-PRF in the treatment of interfacial rejuvenation, in the current clinical activities of aesthetic treatment in the Dentistry field based on clinical evidence. It was based on a systematic search of qualitative nature in databases, evaluating electronic scientific articles published between the years 2013 to 2020. Searches in English and Portuguese were included, with the terms ["platelet rich plasma" OR "Platelet Rich Fibrin Injectable "] AND ["Facial Rejuvenation" OR "rejuvenation"], investigating clinical applications in the studies. The results achieved after therapy with the autologous concentrates PRP and i-PRF report the improvement in the skin appearance and promote the reduction of wrinkles. More detailed studies are needed in order to clarify their quantification and qualification, and the standardization of the methods to obtain these concentrates, in order to expand their use in the aesthetic practice of facial rejuvenation.

scholarly journals Use of PRP, PRF and CGF in Periodontal Regeneration and Facial Rejuvenation—A Narrative Review

Biology ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 317
Author(s):  
Eitan Mijiritsky ◽  
Haya Drora Assaf ◽  
Oren Peleg ◽  
Maayan Shacham ◽  
Loredana Cerroni ◽  
...  
Keyword(s):  
Growth Factors ◽  
Platelet Rich Plasma ◽  
Periodontal Regeneration ◽  
Clinical Work ◽  
Gingival Recession ◽  
Vital Role ◽  
Facial Rejuvenation ◽  
Cochrane Library ◽  
The Past ◽  
Autologous Platelet

Growth factors (GFs) play a vital role in cell proliferation, migration, differentiation and angiogenesis. Autologous platelet concentrates (APCs) which contain high levels of GFs make them especially suitable for periodontal regeneration and facial rejuvenation. The main generations of APCs presented are platelet-rich plasma (PRP), platelet-rich fibrin (PRF) and concentrated growth factor (CGF) techniques. The purpose of this review is to provide the clinician with an overview of APCs’ evolution over the past decade in order to give reliable and useful information to be used in clinical work. This review summarizes the most interesting and novel articles published between 1997 and 2020. Electronic and manual searches were conducted in the following databases: Pubmed, Scopus, Cochrane Library and Embase. The following keywords were used: growth factors, VEGF, TGF-b1, PRP, PRF, CGF and periodontal regeneration and/or facial rejuvenation. A total of 73 articles were finally included. The review then addresses the uses of the three different techniques in the two disciplines, as well as the advantages and limitations of each technique. Overall, PRP is mainly used in cases of hard and soft tissue procedures, while PRF is used in gingival recession and the treatment of furcation and intrabony defects; CGF is mainly used in bone regeneration.

Platelet-Rich Plasma Facial Rejuvenation: Myth or Reality?

2022 ◽  
Author(s):  
Rosita Pensato ◽  
Antonio Zaffiro ◽  
Mirella D’Andrea ◽  
Concetta Errico ◽  
Jean Paul Meningaud ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Facial Rejuvenation

Platelet-Rich Plasma Injections

2018 ◽  
Author(s):  
Juewon Khwarg ◽  
Daniel A. Fung ◽  
Corey Hunter ◽  
Timothy T. Davis
Keyword(s):  
Clinical Evidence ◽  
Scientific Literature ◽  
Platelet Rich Plasma ◽  
Direct Application ◽  
Therapeutic Effects ◽  
Regenerative Processes ◽  
Autologous Plasma ◽  
The Past ◽  
Preparation Techniques ◽  
Insight Into

Platelet-rich plasma (PRP) is an autologous plasma suspension enriched with a supraphysiologic concentrate of platelets, isolated through a process of centrifugation. Administered locally (usually by injection or direct application) to areas of injury, PRP contains a high density of growth factors, which are believed to potentiate the body’s natural regenerative processes. Over the past 20 years, interest in PRP therapy has grown exponentially, as it offers a relatively safe, autologous treatment modality. It has gained particular popularity for a wide variety of musculoskeletal pathologies. There is a growing body of scientific literature that is giving further insight into PRP’s therapeutic effects. This chapter will review the history, preparation techniques, basic science justifications, current clinical evidence, as well as procedural considerations for the therapeutic use of PRP.

Assessment of Efficacy of Platelet-Rich Plasma Injection for Facial Rejuvenation

2019 ◽  
Vol 87 (June) ◽  
pp. 1371-1376
Author(s):  
NOHA N. DOGHIM, M.D. RANIA A. EL-TATAWY, M.D. ◽  
YOMNA M. NEINAA, M.D. ZAMZAM M. IBRAHIM, M.Sc.
Keyword(s):  
Platelet Rich Plasma ◽  
Facial Rejuvenation ◽  
Plasma Injection

Knee Intraosseous Injections: A Systematic Review of Clinical Evidence of Different Treatment Alternatives

Cartilage ◽  
2020 ◽  
pp. 194760352095940 ◽  
Author(s):  
Berardo Di Matteo ◽  
Alberto Polignano ◽  
Francesco Onorato ◽  
Agostino La Porta ◽  
Francesco Iacono ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Adverse Events ◽  
Clinical Evidence ◽  
Platelet Rich Plasma ◽  
Safe Procedure ◽  
Level Of Evidence ◽  
Beneficial Effects ◽  
Short Term Evaluation ◽  
Bone Substitute Materials ◽  
Term Evaluation

Objective To systematically review the available clinical evidence regarding the safety and efficacy of knee intraosseous injections for the treatment of bone marrow lesions in patients affected by knee osteoarthritis. Design A literature search was carried out on PubMed, Embase, and Google Scholar databases in January 2020. The following inclusion criteria were adopted: (1) studies of any level of evidence, dealing with subchondral injection of bone substitute materials and/or biologic agents; (2) studies with minimum 5 patients treated; and (3) studies with at least 6 months’ follow-up evaluation. All relevant data concerning clinical outcomes, adverse events, and rate of conversion to arthroplasty were extracted. Results A total of 12 studies were identified: 7 dealt with calcium phosphate administration, 3 with platelet-rich plasma, and 2 with bone marrow concentrate injection. Only 2 studies were randomized controlled trials, whereas 6 studies were prospective and the remaining 4 were retrospective. Studies included a total of 459 patients treated with intraosseous injections. Overall, only a few patients experienced adverse events and clinical improvement was documented in the majority of trial. The lack of any comparative evaluation versus subchondral drilling alone is the main limitation of the available evidence. Conclusions Knee intraosseous injections are a minimally invasive and safe procedure to address subchondral bone damage in osteoarthritic patients. They are able to provide beneficial effects at short-term evaluation. More high-quality evidence is needed to confirm their potential and to identify the best product to adopt in clinical practice.

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