scholarly journals A RARE CASE OF COLON CANCER IN A YOUNG PATIENT: A CASE REPORT AND LITERATURE REVIEW

2021 ◽  
Vol 9 (11) ◽  
pp. 454-458
Author(s):  
Reem Mohammed Alshiakh ◽  
◽  
Ahmad Omar Alghamdi ◽  
Suhad Ali Aljuhani ◽  
Hadeel Hamid Ahmad ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Case Report ◽  
Clinical Symptoms ◽  
Hepatic Flexure ◽  
Malignant Neoplasms ◽  
Average Risk ◽  
Sessile Polyp ◽  
Screening Guidelines ◽  
Histopathology Result ◽  
The Right

Malignant neoplasms of the colon and rectum are often missed in patients younger than 45 years, the uncertainty of the diagnosis by the surgical team due to unavailability of clear screening guidelines in this population may be one of the reasons. The objective of this case report is to highlight the occurrence of colon cancer in a patient younger than 45 years to avoid the delay in management and the need for clear screening guidelines. Our patient, a 30 years old lady with an average risk of colon cancer demonstrated clinical symptoms and signs suggestive of partial bowel obstruction. After full radiological and laboratory investigations, she was initially diagnosed with inflammatory vs infectious cause of this obstruction. Colonoscopy showed a mass in the right hepatic flexure and sessile polyp in the transverse colon, Histopathology result showed moderately differentiated colon cancer. The patient was taken to the operation theater, right extended hemicolectomy was done, final histopathology result showed stage IIIc cancer, the patient was sent for oncology. In a conclusion, Colon cancer in patients younger than 45 years old requires a high index of suspicion by the surgeon and the managing team despite the unavailability of clear guidelines for screening at a young age.

scholarly journals A case report of unilateral conductive hearing loss as a consequence of malignant sinonasal melanoma: the importance of completing a full clinical history and examination

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Victoria Blackabey ◽  
Olivia Kenyon ◽  
Rishi Talwar
Keyword(s):  
Hearing Loss ◽  
Case Report ◽  
Clinical Symptoms ◽  
Symptomatic Relief ◽  
Clinical History ◽  
Histological Diagnosis ◽  
Unusual Presentation ◽  
Sinus Surgery ◽  
Cancer Management ◽  
The Right

Abstract Background Sinonasal melanoma is a rare head and neck tumour. It is associated with a poor prognosis, high rates of loco-regional recurrence and distant metastasis. Treatment of the disease is therefore complicated, and because of limited data regarding the cancer, management is frequently tailored to the individual patient. We describe an unusual presentation of sinonasal melanoma with relevant histology, radiology and clinical photography. Case presentation The case report describes the presentation of a 64-year-old man to the Ear, Nose and Throat department with progressive right-sided hearing loss. A thorough history highlighted other clinical symptoms including unilateral nasal obstruction and epistaxis. Clinical examination showed a right middle ear effusion with a polypoidal lesion in the right nasal cavity. Relevant imaging demonstrated a destructive process that required further assessment. An endoscopic sinus procedure was performed to obtain histological diagnosis as well as providing symptomatic relief. Histology confirmed malignant mucosal melanoma. The patient underwent maxillectomy and orbital exenteration (due to further progression of disease) at a tertiary centre with a plan for subsequent immunotherapy. This however has been delayed due to further surgery to excise a metastatic lesion to the right femur. Conclusions This case report highlights the importance of a thorough clinical history and examination. An unusual presentation of a sinonasal tumour can easily be missed leading to a significant delay in treatment. The case report also describes the use of functional endoscopic sinus surgery in order to obtain histological diagnosis and to debulk the tumour, providing symptomatic relief. The current literature regarding management will be discussed as well as current developments guiding future treatment.

scholarly journals Unclear Retroperitoneal Tumors, an Interdisciplinary Challenge – A Case Report and Review of the Literature

2021 ◽  
Author(s):  
Benno Traub ◽  
Benedikt Haggemüller ◽  
Lisa Baumann ◽  
Johannes Lemke ◽  
Doris Henne-Bruns ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Symptoms ◽  
Malignant Tumors ◽  
Tumor Resection ◽  
Vena Cava ◽  
Retroperitoneal Tumors ◽  
Common Clinical Presentation ◽  
One Year ◽  
The Right ◽  
Upper Abdomen

Abstract BackgroundUnclear retroperitoneal tumors still impose major challenges for clinicians. Tumors can originate primarily from retroperitoneal tissue or secondarily invade into the retroperitoneal space. While benign lesions also occur, malignant tumors are far more common. Clinical presentation often depends on replacement or invasion of other organs and is therefore highly variable. The heterogeneous tumor composition makes a definitive preoperative diagnosis difficult. Nevertheless, surgical resection is the gold standard for treatment but often proves challenging due to frequent involvement of large retroperitoneal vessels.Case presentationWe present a case report of a 70-year old woman diagnosed with a large, unclear retroperitoneal tumor. Initial clinical symptoms were increasing dyspnea and dysphagia in our clinic. Gastroenterologic and cardiologic workup was unremarkable. Computed Tomography (CT) revealed a large retroperitoneal mass in the right upper abdomen with severe displacement of the inferior vena cava and renal veins. Without signs of irresectability, the patient was scheduled for tumor resection. The procedure was challenging due to the vessel involvement and large blood pressure alterations during tumor mobilization. The post-op pathologic workup then revealed the rare finding of a completely resected paraganglioma. The post-surgical course was uneventful. One year after diagnosis, the patient is relapse-free.CconclusionThis case impressively shows the challenges of retroperitoneal tumors and the importance of interdisciplinary work in these cases.

scholarly journals Localized Adenomyomatosis of Gallbladder Mimicking Advanced Hepatic Flexure Colon Cancer: A Case Report

2018 ◽  
Vol 79 (5) ◽  
pp. 290
Author(s):  
Pae Sun Suh ◽  
Bohyun Kim ◽  
Dakeun Lee ◽  
Ki Myung Lee ◽  
Jei Hee Lee ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Case Report ◽  
Hepatic Flexure

scholarly journals Case report: Liposarcoma of the breast in a man

Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
Marina Fontes Medeiros ◽  
Soraya de Paula Paim ◽  
Rachel Saraiva Teatini Selim de Sales ◽  
Thássia Mariz de Melo ◽  
Janaina Cotta Rodrigues Ferreira
Keyword(s):  
Case Report ◽  
Soft Tissues ◽  
Metastatic Potential ◽  
Malignant Neoplasms ◽  
Safety Margins ◽  
Muscle Fascia ◽  
Progressive Growth ◽  
Belo Horizonte ◽  
Well Differentiated ◽  
The Right

Introduction: Sarcomas are a heterogeneous group of malignant neoplasms and represent less than 1% of neoplasms among adults; 80% of these cases originate in soft tissues. The liposarcoma corresponds to 20% of the subtypes of sarcoma in adults. Objectives: To present a rare case of liposarcoma of the breast. Methods: We studied the case of A.N.R, a 54-year old male patient, from Belo Horizonte, Minas Gerais, presenting a progressive growth nodule in the right breast. Mammography and breast ultrasound suggested lipoma. Core-needle biopsy of the nodule in the right breast was performed, and the anatomopathological was compatible with lipoma. Case report: Due to the progressive growth, the patient was submitted to nodule resection, with safety margins. Anatomopathological and immunohistochemical of the surgical piece were compatible with well-differentiated liposarcoma. The patient was followed-up by the oncologist and had a staging computed thoracic and abdominal tomography without changes, thus not indicative of adjuvant treatment. Discussion: Liposarcoma presents as a painless mass, of progressive growth, being more common in extremities and the retroperitoneum. When the well-differentiated morphological subgroup is located in the extremities and the torso, its excision is curative, and its metastatic potential is null in comparison to other locations; however, it is not recommended to underestimate the risk of local recurrence. Conclusion: even though the prevalence of benign lesions in soft tissues is higher than malignant lesions, it is important to consider a differential diagnosis of malignancy when the behavior and presentation of the tumor are atypical (deep location to the muscle fascia, larger than 5 centimeters, progressive growth), therefore leading to better surgical and therapeutic planning and to a more accurate treatment for the patient.

scholarly journals Laparoscopic Repair of Morgagni Hernia Combined with Right Hemicolectomy for Bleeding Ascending Colon Carcinoma Lodged within the Chest: A Case Report and Review of the Literature

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Oluwatobi O Onafowokan ◽  
Kiran Khosa ◽  
Hugo Bonatti
Keyword(s):  
Colon Cancer ◽  
Case Report ◽  
Hernia Repair ◽  
Laparoscopic Hernia Repair ◽  
Laparoscopic Approach ◽  
Rare Condition ◽  
Right Hemicolectomy ◽  
Morgagni Hernia ◽  
The Right ◽  
Diaphragmatic Hernias

Background. Morgagni hernias are rare in adults and may be asymptomatic but, nevertheless, require surgical repair, with laparoscopy offering an excellent option. The colon dislodged into the chest through diaphragmatic hernias may be affected by various disorders, including malignancies. Case Report. A 70-year-old obese male presented with fatigue and shortness of breath. CT scan showed the right colon lodged in the chest through a Morgagni hernia. He was anaemic, and colonoscopy revealed a colon cancer. He underwent combined laparoscopic hernia repair with bioabsorbable mesh and right hemicolectomy. Recovery was uneventful, but the patient died 5 months later from chemotherapy-associated cardiac failure. Literature review revealed eight similar published cases, and including ours, there were seven Morgagni hernias, one traumatic hernia, and one Bochdalek hernia. Median age of the five men and four women was 66 (range 49-85) years. Surgical approach was thoracotomy (2), laparotomy (5), and laparoscopy (2). Conclusion. Outcome of the rare condition is determined by the course of the colon cancer. Hernia repair was successful in ours and all other published cases. A combined laparoscopic approach can be safely done.

Metastatic Pulmonary Calcification With Coexisting Nonspecific Interstitial Pneumonia: A Case Report

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S52-S52
Author(s):  
Arati Inamdar ◽  
Rajiv Pulinthanathu
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Interstitial Pneumonia ◽  
Clinical Symptoms ◽  
Ground Glass ◽  
Rapid Progression ◽  
Pulmonary Calcification ◽  
Nonspecific Interstitial Pneumonia ◽  
The Right ◽  
Metastatic Pulmonary Calcification

Abstract Patients with underlying chronic kidney disease (CKD) often have elevated serum calcium and parathyroid hormones due to compromised kidney function. We present a case of a 63-year-old female nonsmoker with surgical history of three renal transplants (at age 47, 51, and 58) along with thyroidectomy and parathyroidectomy who came to the emergency department with complaint of persistent dry cough and shortness of breath for the last 2 months. The patient had been on immunosuppressive drugs, tacrolimus, prednisolone, and mycophenolic acid since her first renal transplant as well as on cinacalcet after parathyroidectomy (at age 54). Initial computed tomography (CT) scan demonstrated ground-glass opacities in bilateral upper lobes while bronchoscopy revealed few inflammatory cells without any fungi or bacteria. Repeat CT scan performed 5 days later due to rapid progression of her clinical symptoms showed worsening of ground-glass opacities in bilateral upper lobes and new nodules in right middle and lower lung lobes. The wedge lung biopsy revealed metastatic pulmonary calcification (MPC) in the right upper lobe while nonspecific interstitial pneumonia (NISP) in the right lower lobe confirmed the coexistence of two different pathological processes most likely complicating the patient’s clinical symptoms. Despite comprehensive medical therapy, patient’s symptoms have been progressively worsening and she is currently undergoing evaluation for both renal and lung transplants. Our case report not only presents a rare case of MPC coexisting with NSIP but also sheds light on the associated morbidity due to pulmonary diseases in CKD patients.

scholarly journals Treatment of Middle Cerebral Artery Occlusion with Concomitant Partially Thrombosed Aneurysm: a Case Report

2020 ◽  
Vol 2 (12) ◽  
pp. 2907-2910
Author(s):  
Michel Klapp Oliger ◽  
Till-Karsten Hauser ◽  
Franz-Josef Strauss ◽  
Ulrike Ernemann
Keyword(s):  
Ischemic Stroke ◽  
Case Report ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Clinical Symptoms ◽  
Recombinant Tissue Plasminogen Activator ◽  
Artery Occlusion ◽  
Clinical Approach ◽  
Thrombosed Aneurysm ◽  
The Right

AbstractA 68-year-old female with an acute ischemic stroke demanding emergency thrombectomy which was complicated by the presence of an intracranial aneurysm. Computer tomography revealed the occlusion of the right middle cerebral artery with a distal non-ruptured partially thrombosed aneurysm. The treatment consisted in the administration of intravenous recombinant tissue plasminogen activator and the removal of the proximal thrombus via direct aspiration in order to prevent perforation of the distal aneurysm. After the procedure, the clinical symptoms improved significantly indicated by the National Institutes of Health Stroke Scale (NIHSS). The aim of the present case report is, therefore, to suggest a clinical approach to help physicians in the decision-making process for early and safe revascularization in patients with ischemic stroke and intracranial aneurysms.

scholarly journals Sudden Odynophagia and Globus—A Unique Presentation of a Nonsecreting Parathyroid Adenoma: A Case Report and Literature Review

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Luxman Srikantha ◽  
Esmael H. Amjad ◽  
Rafic Beydoun
Keyword(s):  
Case Report ◽  
Parathyroid Adenoma ◽  
Clinical Symptoms ◽  
Surgical Excision ◽  
Laryngeal Nerve ◽  
Range Imaging ◽  
Normal Range ◽  
Parathyroid Adenomas ◽  
The Right ◽  
Point Tenderness

Parathyroid adenomas are most commonly diagnosed when symptoms consistent with primary hyperparathyroidism arise. However, certain parathyroid glands may enlarge without such symptoms. Described here is a case in which a patient presented with acute signs of unilateral cervical point tenderness, dysphagia, and odynophagia. Calcium and parathyroid hormone levels tested within normal range. Imaging revealed an enlarged right-sided mass, with compression of the trachea-esophageal groove and potentially the right recurrent laryngeal nerve. Surgical excision was performed, and final pathology revealed an infarcted parathyroid adenoma. Clinical symptoms promptly resolved thereafter. Current NIH criteria for parathyroidectomy include various symptoms of hyperparathyroidism but do not include the above findings. Nonsecreting parathyroid adenomas rarely cause laryngeal symptoms, as this has only been documented once before.

scholarly journals Intraneural glomus tumor within digital nerve: a case report

2022 ◽  
Author(s):  
Sehun Kim
Keyword(s):  
Case Report ◽  
Glomus Tumor ◽  
Clinical Symptoms ◽  
Proximal Interphalangeal Joint ◽  
Careful Examination ◽  
Digital Nerve ◽  
Cold Intolerance ◽  
Results Of Treatment ◽  
Traumatic History ◽  
The Right

A glomus tumor is a soft tissue tumor that arises from the glomus body, a peripheral organ responsible for temperature regulation of the skin. It accounts for about 1% to 5% of tumors occurring in the hand, is mainly located in the subungal, and is less than 1 cm in size. Diagnosis is mainly based on clinical symptoms, and the main symptoms are pain at the site of glomus tumor, pinpoint tenderness, and cold intolerance. The pain is severe and usually requires surgical resection, and the results of treatment are good with complete resection of the tumor. In this case report, the patient is a 37-year-old female who developed pain in the radial side around the proximal interphalangeal joint of the right second finger without any traumatic history. On physical examination and imaging, it was diagnosed as a glomus tumor of the digital nerve and resected. After surgery, the symptoms improved and there was no recurrence. A careful examination and accurate diagnosis and treatment are necessary for symptomatic masses.

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