scholarly journals EVALUATION OF THE EFFECT OF HYALURONIC ACID MIXED WITH BIPHASIC CALCIUM PHOSPHATE ON BONE HEALING AROUND DENTAL IMPLANTS (EXPERIMENTAL STUDY)

2017 ◽  
Vol 42 (1) ◽  
pp. 104-107
Author(s):  
Mostafa M. Shamma ◽  
Sherif S. Ayad ◽  
Riham M. El-dibany ◽  
Dina A. Nagui
Keyword(s):  
Experimental Study ◽  
Hyaluronic Acid ◽  
Calcium Phosphate ◽  
Dental Implants ◽  
Bone Healing ◽  
Biphasic Calcium Phosphate

Bone regeneration of multichannel biphasic calcium phosphate granules supplemented with hyaluronic acid

2019 ◽  
Vol 99 ◽  
pp. 1058-1066 ◽  
Author(s):  
Mirana Taz ◽  
Preeti Makkar ◽  
Khan Mohammad Imran ◽  
D.W. Jang ◽  
Yong-Sik Kim ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Calcium Phosphate ◽  
Bone Regeneration ◽  
Biphasic Calcium Phosphate

scholarly journals Bone Loss around Dental Implants 5 Years after Implantation of Biphasic Calcium Phosphate (HAp/βTCP) Granules

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Vadims Klimecs ◽  
Alexanders Grishulonoks ◽  
Ilze Salma ◽  
Laura Neimane ◽  
Janis Locs ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Calcium Phosphate ◽  
Bone Loss ◽  
Dental Implants ◽  
Biphasic Calcium Phosphate ◽  
Alveolar Bone ◽  
Clinical Situation ◽  
Cone Beam ◽  
Calcium Phosphate Ceramic ◽  
Middle Point

Biphasic calcium phosphate ceramic granules (0.5–1.0 mm) with a hydroxyapatite and β-tricalcium phosphate ratio of 90/10 were used. Biphasic calcium phosphate ceramic granules produced in the Riga Technical University, Riga Rudolph Cimdins Biomaterials Innovation and Development Centre, were used for filling the bone loss on 18 patients with peri-implantitis. After 5 years at the minimum, clinical and 3D cone-beam computed tomography control was done. Clinical situation confirmed good stability of implants without any signs of inflammation around. Radiodensity of the previous gap and alveolar bone horizontally from middle point of dental implants showed similar radiodensity as in normal alveolar bone. This trial is registered with ISRCTN13514478.

Bone Healing around Titanium and Titanium Nitride-Coated Dental Implants with Three Surfaces: An Experimental Study in Rats

2003 ◽  
Vol 5 (2) ◽  
pp. 103-111 ◽  
Author(s):  
Antonio Scarano ◽  
Maurizio Piattelli ◽  
Giuseppe Vrespa ◽  
Giovanna Petrone ◽  
Giovanna Iezzi ◽  
...  
Keyword(s):  
Experimental Study ◽  
Titanium Nitride ◽  
Dental Implants ◽  
Bone Healing

Processing and Characterization of a Composite of Hyaluronic Acid (HA) and Microspheres Biphasic Calcium Phosphate (BCP) for Dermal Repair

2012 ◽  
Vol 529-530 ◽  
pp. 421-425
Author(s):  
Edirlaine Soares Silva ◽  
Deny Gomes de Freitas ◽  
Sidney Nicodemos da Silva
Keyword(s):  
Hyaluronic Acid ◽  
Calcium Phosphate ◽  
Soft Tissue ◽  
Biphasic Calcium Phosphate ◽  
Soft Tissues ◽  
Biological Response ◽  
Water Soluble ◽  
Potential Candidate ◽  
Dermal Fillers

Dermal fillers are injectable implants made of biological materials (collagen, autologous fat and hyaluronic acid animal) or synthetic (PMMA microparticles of hydroxyapatite and non-animal hyaluronic acid), biodegradable or not, that include features such as ideal biocompatibility, durability, non-profile migration and ability to promote a smooth, natural-looking correction. Its main indication is intended to treat contour defects caused by aging, photo damage, disease, trauma or scarification. The fact of biodegradable fillers are absorbed within a year after application resulted in the emergence of products permanent and semi-permanent to offer patients long-lasting effects. Currently, one of the most effective strategies has been the development of scaffolds formed by combining two or more biomaterials seeking the restoration of tissue function. The bioceramic associated with water-soluble polymers have been developed as substitutes for the repair of soft tissues with optimal biological response. The objective of this study was to process and characterize a composite hydrogel in the form of hyaluronic acid (HA) microspheres and biphasic calcium phosphate (BCP) in order injectable applications for repair of soft tissue. The powders of HA and BCP were characterized by Infrared Spectroscopy Fourier Transform (FTIR) and X-ray diffraction (XRD) and Scanning Electron Microscopy (SEM). The characterization of the hydrogel injectability pure and the composite with different ratios of HA and BCP was performed. The components were characterized compatible for use as dermal fillers. The composite of hyaluronic acid (HA) and biphasic calcium phosphate (BCP) had adequate characterization and injetabilidade proving to be a potential candidate for restoration of soft tissue.

In Vivo Performance of an Injectable Biphasic Calcium Phosphate Bone Filler

2008 ◽  
Vol 396-398 ◽  
pp. 583-586
Author(s):  
Pierre Layrolle ◽  
Serge Baroth ◽  
Eric Goyenvalle ◽  
Eric Aguado ◽  
Françoise Moreau ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Healing ◽  
Biphasic Calcium Phosphate ◽  
Bone Ingrowth ◽  
Submicron Particles ◽  
Bone Filler ◽  
Osteoclastic Resorption ◽  
Tcp Phases

An hydrated putty was prepared by mixing submicron particles, rounded particles and granules of Biphasic Calcium Phosphate (BCP) ceramics composed of HA and β-TCP phases. The material filled entirely critical sized defects in the femoral epiphysis of NZW rabbits. After 3, 6 and 12 weeks, histology revealed that submicron particles were rapidly degraded by multinucleated TRAP-positive cells. This osteoclastic resorption stimulated bone ingrowth while the large BCP particles served as scaffold supporting bone healing by osteoconduction.

scholarly journals Assessment of biphasic calcium phosphate 70/30 alginate scaffold on the tibia in pigs

2020 ◽  
Vol 13 (12) ◽  
pp. 2635-2642
Author(s):  
Gunanti Soeyono ◽  
Kiagus Dahlan ◽  
Melpa Susanti Purba ◽  
Sus Dherthi Widhyari ◽  
Rr. Soesatyoratih ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Healing ◽  
Biphasic Calcium Phosphate ◽  
Tissue Growth ◽  
Radiographic Images ◽  
Beta Tricalcium Phosphate ◽  
The Right ◽  
Implant Density ◽  
Operation Results ◽  
Alginate Scaffold

Background and Aim: Calcium phosphate bioceramics have been used for at least a decade, and many investigations have focused on the use of hydroxyapatite (HA) derivative in the regeneration of bone defects. Biphasic calcium phosphate (BCP) is a biomaterial composed of HA and beta-tricalcium phosphate (BCP), with a structure similar to bone. The aim of the study was to determine the influence of the BCP/alginate scaffold on tissue growth, blood, the lungs, and the electrical activity of the heart during bone healing in the tibia of pig. Materials and Methods: Three pigs were implanted with BCP/alginate scaffolds in the tibias. Pigs were acclimatized and treated with antibiotics and anthelminthic drugs 14 days before implantation. Each pig was implanted with a BCP/ alginate scaffold in the right tibia and a defect without the implant was made in the left tibia as the control. Radiographic images of the tibia were captured 0, 7, 30, and 60 days after the operation. Erythrograms, radiography of the lungs, and electrocardiogram (ECG) recordings were done 0, 30, and 60 days after the operation. Results: Radiographic evaluations showed that the implant and peri-implant density of BCP decreased throughout the process of bone healing. The erythrogram profile indicated that a substantial amount of time (60 days) was required to adapt and return to pre-operative conditions. No significant differences in ECG recordings or pulmonary radiography were detected. Conclusion: The BCP/alginate scaffold did not induce a faster recovery rate from the bone defect compared to the control with no implant. However, the BCP/alginate scaffold was biodegradable, bioresorbable, and non-toxic.

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