A Study on the Rearrangement of Dialkyl 1-Aryl-1-hydroxymethylphosphonates to Benzyl Phosphates

2020 ◽  
Vol 24 (4) ◽  
pp. 465-471 ◽  
Author(s):  
Zita Rádai ◽  
Réka Szabó ◽  
Áron Szigetvári ◽  
Nóra Zsuzsa Kiss ◽  
Zoltán Mucsi ◽  
...  
Keyword(s):  
Quantum Chemical ◽  
Room Temperature ◽  
Phase Transfer ◽  
One Pot ◽  
Substrate Dependence ◽  
Triethylbenzylammonium Chloride ◽  
One Step ◽  
The Pudovik Reaction ◽  
The One ◽  
Solid Liquid

The phospha-Brook rearrangement of dialkyl 1-aryl-1-hydroxymethylphosphonates (HPs) to the corresponding benzyl phosphates (BPs) has been elaborated under solid-liquid phase transfer catalytic conditions. The best procedure involved the use of triethylbenzylammonium chloride as the catalyst and Cs2CO3 as the base in acetonitrile as the solvent at room temperature. The substrate dependence of the rearrangement has been studied, and the mechanism of the transformation under discussion was explored by quantum chemical calculations. The key intermediate is an oxaphosphirane. The one-pot version starting with the Pudovik reaction has also been developed. The conditions of this tandem transformation were the same, as those for the one-step HP→BP conversion.

scholarly journals Trifluoroacetic Acid Hydroxylamine System as Organocatalyst Reagent in a One-Pot Salt Free Process for the Synthesis of Caprolactam and Amides of Industrial Interest

2021 ◽  
Author(s):  
F. Manente ◽  
L. Pietrobon ◽  
L. Ronchin ◽  
A. Vavasori
Keyword(s):  
Trifluoroacetic Acid ◽  
Room Temperature ◽  
Beckmann Rearrangement ◽  
One Pot ◽  
Free Process ◽  
Hydrogenation Reactions ◽  
One Step ◽  
The One ◽  
Industrial Relevance

AbstractIn this work we studied the reactivity of the Trifluoroacetic acid hydroxylamine system in the one step salt free synthesis of amides from ketones. A particular regards was paid to the caprolactam synthesis because of its industrial relevance. Synthesis, reactivity and characterization of the hydroxylamine trifluoroacetate is given. Fast oximation reaction of several ketones was gained at room temperature (1 h of reaction quantitative conversion for several ketones). In the same reactor, by raising the temperature at 383 K, the Beckmann rearrangement of the so obtained oximes is easily accomplished in the presence of three equivalent of TFA. The possibility of obtaining the trifluoroacetate of the hydroxylamine with a modified nitric acid hydrogenation reactions was verified, too. Reuse of solvent and trifluoroacetic acid is easily achieved by distillation. Graphical abstract Salt free one-pot caprolactam and amides process catalyzed by CF3COOH, in the presence of NH2OH TFA as the oximation agent.

scholarly journals Sustainable One-Pot Immobilization of Enzymes in/on Metal-Organic Framework Materials

Catalysts ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1002 ◽  
Author(s):  
M. Asunción Molina ◽  
Victoria Gascón-Pérez ◽  
Manuel Sánchez-Sánchez ◽  
Rosa M. Blanco
Keyword(s):  
Room Temperature ◽  
Metal Organic Framework ◽  
One Pot ◽  
Framework Materials ◽  
Immobilization Of Enzymes ◽  
Metal Organic ◽  
One Step ◽  
The One ◽  
Synthetic Approaches ◽  
Organic Framework

The industrial use of enzymes generally necessitates their immobilization onto solid supports. The well-known high affinity of enzymes for metal-organic framework (MOF) materials, together with the great versatility of MOFs in terms of structure, composition, functionalization and synthetic approaches, has led the scientific community to develop very different strategies for the immobilization of enzymes in/on MOFs. This review focuses on one of these strategies, namely, the one-pot enzyme immobilization within sustainable MOFs, which is particularly enticing as the resultant biocomposite Enzyme@MOFs have the potential to be: (i) prepared in situ, that is, in just one step; (ii) may be synthesized under sustainable conditions: with water as the sole solvent at room temperature with moderate pHs, etc.; (iii) are able to retain high enzyme loading; (iv) have negligible protein leaching; and (v) give enzymatic activities approaching that given by the corresponding free enzymes. Moreover, this methodology seems to be near-universal, as success has been achieved with different MOFs, with different enzymes and for different applications. So far, the metal ions forming the MOF materials have been chosen according to their low price, low toxicity and, of course, their possibility for generating MOFs at room temperature in water, in order to close the cycle of economic, environmental and energy sustainability in the synthesis, application and disposal life cycle.

A Series of Metal-Organic Frameworks for Selective CO2 Capture and Catalytic Oxidative Carboxylation of Olefins

2018 ◽  
Author(s):  
Huong T. D. Nguyen ◽  
Y B. N. Tran ◽  
Hung N. Nguyen ◽  
Tranh C. Nguyen ◽  
Felipe Gándara ◽  
...  
Keyword(s):  
Room Temperature ◽  
Gas Adsorption ◽  
New Materials ◽  
One Pot ◽  
Acid Gas ◽  
Naphthalene Diimide ◽  
Styrene Carbonate ◽  
Metal Organic ◽  
Adsorption Of Co ◽  
The One

<p>Three novel lanthanide metal˗organic frameworks (Ln-MOFs), namely MOF-590, -591, and -592 were constructed from a naphthalene diimide tetracarboxylic acid. Gas adsorption measurements of MOF-591 and -592 revealed good adsorption of CO<sub>2</sub> (low pressure, at room temperature) and moderate CO<sub>2</sub> selectivity over N<sub>2</sub> and CH<sub>4</sub>. Accordingly, breakthrough measurements were performed on a representative MOF-592, in which the separation of CO<sub>2</sub> from binary mixture containing N<sub>2</sub> and CO<sub>2</sub> was demonstrated without any loss in performance over three consecutive cycles. Moreover, MOF-590, MOF-591, and MOF-592 exhibited catalytic activity in the one-pot synthesis of styrene carbonate from styrene and CO<sub>2</sub> under mild conditions (1 atm CO<sub>2</sub>, 80 °C, and solvent-free). Among the new materials, MOF-590 revealed a remarkable efficiency with exceptional conversion (96%), selectivity (95%), and yield (91%). </p><br>

scholarly journals Clean one-pot multicomponent synthesis of pyrans using a green and magnetically recyclable heterogeneous nanocatalyst

SynOpen ◽  
2021 ◽  
Author(s):  
Mina Ghassemi ◽  
Ali Maleki
Keyword(s):  
Room Temperature ◽  
Significant Loss ◽  
Copper Ferrite ◽  
Multicomponent Synthesis ◽  
Thermo Gravimetric ◽  
Sem Images ◽  
One Pot ◽  
Three Component Reaction ◽  
Ft Ir ◽  
The One

Copper ferrite (CuFe2O4) magnetic nanoparticles (MNPs) were synthesized via thermal decomposition method and applied as a reusable and green catalyst in the synthesis of functionalized 4H-pyran derivatives using malononitrile, an aromatic aldehyde and a β-ketoester in ethanol at room temperature. Then it was characterized by Fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX) analysis, scanning electron microscopy (SEM) images, thermo gravimetric and differential thermo gravimetric (TGA/DTG) analysis. The catalyst was recovered from the reaction mixture by applying an external magnet and decanting the mixture. Recycled catalyst was reused for several times without significant loss in its activity. Running the one-pot three-component reaction at room temperature, no use of eternal energy source and using a green solvent provide benign, mild, and environmentally friendly reaction conditions; as well, ease of catalyst recovering, catalyst recyclability, no use of column chromatography and good to excellent yields are extra advantages of this work.

Study of Antioxidant Property of the Rhizome Extract of Polygonatum cirrhifolium (Mahameda) and its use in the green synthesis of Gold nanoparticles

2017 ◽  
Vol 1 (2) ◽  
Author(s):  
Braja Gopal Bag ◽  
Shib Shankar Dash ◽  
Anup Mandal
Keyword(s):  
Gold Nanoparticles ◽  
Green Synthesis ◽  
Room Temperature ◽  
Chemical Constituents ◽  
Antioxidant Property ◽  
Dpph Radical ◽  
Mild Conditions ◽  
One Step ◽  
The One

The antioxidant efficacy of the rhizome extract of Polygonatum cirrhifolium (Mahameda) has been studied against a stable 2, 2-diphenylpicrylhydrazyl (DPPH) radical at room temperature. The chemical constituents present in the rhizome extract have been utilized for the one step synthesis of stable gold nanoparticles at room temperature under very mild conditions.

Synthesis of a titanium ethylene complex via C–H-activation and alternative access to Cp2Ti(η2-Me3SiC2SiMe3)

2020 ◽  
Vol 49 (7) ◽  
pp. 2068-2072 ◽  
Author(s):  
Malte Fischer ◽  
Lisa Vincent-Heldt ◽  
Malena Hillje ◽  
Marc Schmidtmann ◽  
Ruediger Beckhaus
Keyword(s):  
Room Temperature ◽  
One Pot ◽  
Transformation Protocol ◽  
One Step

The synthesis of a room temperature stable titanacyclopropane in a one-step-two-transformation protocol is presented. Additionally, a novel one-pot procedure toward Cp2Ti(η2-Me3SiC2SiMe3) was subsequently developed.

scholarly journals Rhodium catalyzed cascade cyclization featuring B–H and C–H activation: one-step construction of carborane-fused N-polyheterocycles

2018 ◽  
Vol 9 (30) ◽  
pp. 6390-6394 ◽  
Author(s):  
Hairong Lyu ◽  
Yangjian Quan ◽  
Zuowei Xie
Keyword(s):  
Reaction Mechanism ◽  
Structural Identification ◽  
One Pot ◽  
Cascade Cyclization ◽  
One Step ◽  
The One

A novel Rh-catalyzed cascade cyclization featuring both carboranyl B–H and aryl C–H activation has been developed, resulting in the one-pot construction of three new B–C and C–C bonds. The isolation and structural identification of a key intermediate provide solid evidence for the reaction mechanism.

Fast and Facile One-Pot One-Step Preparation of Nonisocyanate Polyurethane Hydrogels in Water at Room Temperature

2019 ◽  
Author(s):  
Maxime Bourguignon ◽  
Jean-Michel Thomassin ◽  
Bruno Grignard ◽  
Christine Jerome ◽  
Christophe Detrembleur
Keyword(s):  
Room Temperature ◽  
One Pot ◽  
One Step ◽  
Nonisocyanate Polyurethane

scholarly journals ZnO-beta zeolite mediated simple and efficient method for the one-pot synthesis of quinoxaline derivatives at room temperature

2010 ◽  
Vol 8 (2) ◽  
pp. 320-325 ◽  
Author(s):  
Santosh Katkar ◽  
Pravinkumar Mohite ◽  
Lakshman Gadekar ◽  
Balasaheb Arbad ◽  
Machhindra Lande
Keyword(s):  
Efficient Method ◽  
Room Temperature ◽  
Environmentally Benign ◽  
Beta Zeolite ◽  
Reaction Conditions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Quinoxaline Derivatives ◽  
The One ◽  
Work Up

AbstractA rapid and an efficient one-pot method for the synthesis of quinoxalines catalysed by ZnO-beta zeolite at room temperature is described. This environmentally benign method provides several advantages over methods that are currently employed such as a simple work-up, mild reaction conditions, good to excellent yields, and a process to recover and reuse the catalyst for several cycles with consistent activity.

Ceric ammonium nitrate (CAN): an efficient and eco-friendly catalyst for the one-pot synthesis of alkyl/aryl/heteroaryl-substituted bis(6-aminouracil-5-yl)methanes at room temperature

RSC Advances ◽  
2015 ◽  
Vol 5 (49) ◽  
pp. 39263-39269 ◽  
Author(s):  
Goutam Brahmachari ◽  
Bubun Banerjee
Keyword(s):  
Ammonium Nitrate ◽  
Room Temperature ◽  
Aqueous Ethanol ◽  
Ceric Ammonium Nitrate ◽  
One Pot ◽  
Alkyl Aryl ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
The One

Ceric ammonium nitrate (CAN)-catalyzed one-pot synthesis of alkyl/aryl/heteroaryl-substituted bis(6-aminouracil-5-yl)methane scaffolds (3a–3u) has been developed via a pseudo three-component reaction in aqueous ethanol at room temperature.

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