A New Fluorescent Salen-uranyl Sensor for the Sub-ppm Detection of Chemical Warfare Agents

2020 ◽  
Vol 24 (20) ◽  
pp. 2378-2382
Author(s):  
Andrea Pappalardo ◽  
Chiara M.A. Gangemi ◽  
Rosa Maria Toscano ◽  
Giuseppe Trusso Sfrazzetto

Real-time sensing of Chemical Warfare Agents (CWAs) is today a crucial topic to prevent the lethal effects of a terroristic chemical attack. For this reason, the development of efficient, selective, sensitive and reversible sensoristic devices, able to detect by optical response ppm levels of these compounds, is strongly required. Here, the synthesis of a new fluorescent sensor based on a salen-uranyl scaffold, functionalized with two bodipy moieties, and its application for the detection of sub-ppm levels of CWAs is reported. Detection properties were evaluated by fluorescence measurements and selectivity tests demonstrated the strong affinity for CWAs.

2020 ◽  
Vol 24 (20) ◽  
pp. 2378-2382
Author(s):  
Andrea Pappalardo ◽  
Chiara M.A. Gangemi ◽  
Rosa Maria Toscano ◽  
Giuseppe Trusso Sfrazzetto

Real-time sensing of Chemical Warfare Agents (CWAs) is today a crucial topic to prevent the lethal effects of a terroristic chemical attack. For this reason, the development of efficient, selective, sensitive and reversible sensoristic devices, able to detect by optical response ppm levels of these compounds, is strongly required. Here, the synthesis of a new fluorescent sensor based on a salen-uranyl scaffold, functionalized with two bodipy moieties, and its application for the detection of sub-ppm levels of CWAs is reported. Detection properties were evaluated by fluorescence measurements and selectivity tests demonstrated the strong affinity for CWAs.


2021 ◽  
Vol 57 (28) ◽  
pp. 3430-3444
Author(s):  
Vinod Kumar

This article describes our journey and success stories in the development of chemical warfare detection, detailing the range of unique chemical probes and methods explored to achieve the specific detection of individual agents in realistic environments.


2009 ◽  
Vol 81 (16) ◽  
pp. 6744-6749 ◽  
Author(s):  
J. Michael Nilles ◽  
Theresa R. Connell ◽  
H. Dupont Durst

2021 ◽  
Vol 136 (5) ◽  
Author(s):  
Dieter Rothbacher

AbstractNATO doctrine considers clearance decontamination to be applicable after the termination of a CBRN incident and largely deems the conduct of clearance decontamination to be a civilian, not a military, capability (NATO Standard NATO STANREC 4784 CBRN Clearance Decontamination, Study Draft 1, November 2015). Clearance decontamination procedures are such that the process is verified as being achieved by determining the residual contamination levels on every part of various surfaces of equipment and infrastructure, and by demonstrating that such levels are below the ones that are pre-determined by the relevant civilian authorities, who are responsible for the safety of the civilian population (NATO Standard NATO STANREC 4784 CBRN Clearance Decontamination, Study Draft 1, November 2015). The current desirable surface contamination detection levels for some Chemical Warfare Agents are technically challenging and may be beyond the capabilities of current technologies of military and civilian authorities. Can those low levels be detected, in real time, with existing technologies? Proton Transfer Reaction–Time of Flight–Mass Spectrometry (PTR–ToF–MS) enables simultaneous real-time detection, monitoring, and quantification of volatile organic compounds. Trials and evaluations with this PTR–ToF–MS technology, using Chemical Warfare Agents as contaminants, will show that this technology is an invaluable asset in supporting civilian authorities when determining safe levels of surface contamination in real time, after the completion of decontamination operations.


2017 ◽  
Vol 1 (2) ◽  
pp. 39-63

The introduction of poison gases by the Germans at Ypres in April 1915 marked a new era in modern warfare. The cylinder attack of the German Army against the French and the British positions at Ypres on April 22, 1915, became the first large-scale appearance of the new kind of weapons, chemical weapons, on the battlefields of World War 1. The widespread use of chemical munitions of different types, numerous toxic agents and their delivery systems (field and heavy artillery, mortars and Livens projectors) by all the belligerents influenced military tactics and operational art at World War 1. In 1915-1916, during the period of trench warfare, the use of chemical weapons for breaking through the enemy`s first defence lines changed the structure of combat orders and led to their dispersal and the deployment in depth of the defensive zone. In 1917 chemical weapons made it possible to overcome the contradiction between the lengthy preliminary artillery bombardment and the surprise of the offensive. The unprecedented artillery chemical bombardments fired by the German Army, artillery chemical battle, resulted in the significant success of the Germans in spring offensives in 1918, when large parts of the front were given up by the retiring Allied forces. The dynamics of the growth of the chemical warfare agents` (CWA) production, the development of means and methods for delivering the agents efficiently to the target by the Allied countries allowed the authors to suggest that in case Germany had not signed the armistice of 11 November 1918 with the Allies, the large-scale battlefield use of chemical weapons could multiply both in quality and in quantity. The development of the bombardment aviation and the inability of Germany to carry out a retaliatory chemical attack, that became obvious at the end of 1918, offered a golden opportunity for the Allies to use chemical agents in 1919 without any legal or humanitarian limitation on the methods of warfare. This article is concerned also with tactical and operational objectives and targets the belligerents tried to achieve by using chemical weapons during separate battles, the evolution of chemical weapons and chemical warfare agents and their joint impact on military operations at the battlefields of World War 1.


Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5731
Author(s):  
Nunzio Tuccitto ◽  
Luca Spitaleri ◽  
Giovanni Li Destri ◽  
Andrea Pappalardo ◽  
Antonino Gulino ◽  
...  

Real-time sensing of chemical warfare agents by optical sensors is today a crucial target to prevent terroristic attacks by chemical weapons. Here the synthesis, characterization and detection properties of a new sensor, based on covalently functionalized carbon nanoparticles, are reported. This nanosensor exploits noncovalent interactions, in particular hydrogen bonds, to detect DMMP, a simulant of nerve agents. The nanostructure of the sensor combined with the supramolecular sensing approach leads to high binding constant affinity, high selectivity and the possibility to reuse the sensor.


2020 ◽  
Vol 20 (11) ◽  
pp. 7151-7157
Author(s):  
Jinuk Kim ◽  
Eunhyun Kim ◽  
Jihyun Kim ◽  
Joo-Hyung Kim ◽  
Seonggyun Ha ◽  
...  

Recently, efforts have been made to adapt surface acoustic waves (SAWs) for use in chemical sensors for detection of chemical warfare agents (CWAs). In this study, a four-channel real-time CWA detection system was constructed using four 250-MHz SAW sensors. Each system consists of three different chemical sensors and one reference sensor. The reference sensor compensates for frequency variations according to humidity and temperature conditions. Signals from the SAW sensors can be checked on a PC-based graphical user interface without additional measuring equipment. To measure dimethyl methylphosphonate (DMMP), a simulant of sarin gas, polyhedral oligomeric silsesquioxane (POSS) and thiourea (TU)-based synthetic polymers were used as sensing materials. The reference sensor was not coated, whereas the three different chemical sensors were coated with POSS, TU-1, and TU-2. The maximum frequencies of POSS, TU-1, and TU-2 were shifted 15.86, 13.85, and 0.944 kHz, showing significant values. We also found a relatively good linear relation between the frequency shift and the concentration of DMMP. The three sensing materials selected-POSS, TU-1, and TU-2-responded significantly to DMMP and triethylphosphate in the selectivity tests. This response is due to the chemical bonding of the sensing materials with the phosphonate in the nerve-agent simulants. These results indicate that the four-channel SAW monitoring system described in this paper shows potential as a portable real-time monitoring system to detect a variety of toxic vapors simultaneously, without using complex measuring equipment. In addition, this approach has demonstrated potential for developing excellent portable sensors to detect different types of CWAs.


Sign in / Sign up

Export Citation Format

Share Document