Advantages and Functions of Clinical and Decision Support Systems

Clinical Decision Support Systems (CDSSs) signify the framework shift in the medical sector in the modern age. CDSSs are utilized in augmenting healthcare facilities in the process of making complex clinical decisions. Since the first application of CDSSs in the 80s, the framework has witnessed significant transformation. The frameworks are now administered through electronic healthcare records with complex capacities. Irrespective of these complex advancements, there are existing questions concerning the impacts of CDSSs on service providers, healthcare costs, and patients’ records. There are many published texts concerning the success stories of CDSSs, but significant setbacks have proved that CDSSs are not without any potential risks. In this research, we provide critical analysis on the application of CDSSs in clinical setting, integrating various forms, present application cases with proven effectiveness, potential harms and common pitfalls. We therefore conclude with evidence-centered recommendation for mitigating the issues of CDSSs maintainability, evaluation, implementation and designing.

Catch-Up Development VS. Forward-Looking Development: from Theoretical Models to Developmental State Practices

The presented article was carried out within the framework of scientific project dedicated to Russia's participation in the export and import of institutions. The solid question arose that the conditions and specificity of Russia's place in these processes are related to its position in the global world economy. These problems are considered within the framework of competing concepts of catch-up and forward-looking development in the economic literature. Comparative characteristics of methodological foundations, provisions and normative recommendations of these concepts are highlighted in the article. The analysis shows that there is no ground to justify the absolutization of their differences. Representatives of competing approaches came to the conclusion that it was necessary to search for the optimal configuration of imported and genuine institutions at the level of specific problems of development of countries that were largely on the periphery of the modern global economy. This configuration provides productive orientation of economic actors and creation of favorable conditions for the development of Schumpeterian type innovations. The solution of these tasks is linked with the formation and activities of developmental state. The functions of such a state are fundamentally different from compensating market failures that is characteristic of developed market economy. Such a state acts as a subject that forms the basic institutions of the economic system. Fundamental importance is its ability to ensure the combination of selective imports of institutions with the modification of genuine institutions that have historical and cultural specificity. Characteristics of the reasons and conditions for the successful solution of these tasks by countries such as Japan, Taiwan and South Korea, are highlighted in the article. The success stories are compared to the experience of partial failure of developmental state in Brazil. The fulfilled study is of interest not only for positive analysis, but also for the elaboration of normative recommendations for the formation of optimal configuration of imported and genuine institutions in contemporary Russia.

Anti-crisis Transformation of Corporate Culture in Russian Companies During the COVID-19 Pandemic

From April 2020 to August 2021 the Public Opinion Foundation conducted a study of the top management of small, medium and large businesses in a pandemic. We focused on “success stories” and on what characteristics of a company determine its survival. Despite the pandemic crisis these organizations were successfully able to adapt, they launched new products and processes, their teams stayed consolidated and in some cases even grew to accommodate new functions. One of the factors of a company’s success and its survival in a crisis is having a system of values shared by all team members, which is an integral part of corporate culture. The heads of companies point out: taking care of the collective means to make a very profitable investment in business development. During the crisis, corporate culture helped managers to preserve a tightly knit team around them, create a certain work atmosphere in the collective and inspire employees to continue growing. This article examines different levels of corporate culture, showing the role of each of them when it comes to the survival of a business in a pandemic crisis. The text also contains the results of a case study and content analysis of 70 in-depth interviews with company leaders, reflecting changes in corporate culture given an ongoing pandemic. Particular attention is paid to the transformation of the role of the business leader. In the final section we consider the specifics of culture for businesses of various sizes, and then summarize the results by outlining areas for future research.

Relevance of developing public health service cadres alongside a more prevention oriented Indian health system: an overview

The relevance of public health has been emphasized in the wake of the global epidemic COVID-19. There are several success stories that we often tend to forget, such as the fight against various infectious illnesses like smallpox, poliomyelitis, and current human-immunodeficiency virus (HIV) prevention, to name a few, public health has played a significant impact. Diarrheal diseases, for example, which contributes significantly to India's under-five mortality rate and is one of the leading causes of malnutrition, can be effectively handled by improving access to safe water and sanitation. Because public health encompasses more than just health, we require a workforce with managerial and leadership skills as well as training in public health as a specialty. This paper explores some of the successes and lessons learned from systematic investments in public health in the Indian state of Tamil Nadu, namely The Tamil Nadu model and other countries, as well as the system's flaws. In India, a feasible framework for establishing dedicated public health cadres has also been explored. Evidence was acquired from PubMed, Google Scholar, newspaper stories, and publicly released government orders and papers. The recruitment of cadres may resemble that of the Indian economic/statistical services (IES/ ISS) by the UPSC. Another area to emphasize for health professionals interested in public health is training. Starting from frontline workers, block level workers to district and state we need dedicated public health workforce. Moreover, the need of the hour is to establish such a system which will work alongside pre-existing clinical fields.

4th Swiss Symposium in Point-of-Care Diagnostics held at the Davos Conference Center on 21 October, 2021

After last year's successful online symposium, the 4th edition of the Swiss Symposium in POC Diagnostics gathered more than 150 participants from medicine, industry and science as well as from different European countries to meet at the Davos Conference Center for an exciting program with 13 expert speakers, a poster session and a product & technology exhibition. The mandatory COVID-certificate to access the event has allowed people to meet (again at last!), network and share their views and success stories in the field of POC Diagnostics that continues to be propelled by digitalization, new technological possibilities, user needs and the COVID-19 pandemic.

Informal Entrepreneurship Education: Overview of the Russian Field

This article analyzes the informal sector of entrepreneurial education — free “open” educational projects at the federal level in the context of broader trends in the development of education and society, including education’s ‘unbundling’. The search for information was carried out using the Internet, as a result 45 initiatives were discovered. The results show that the sector of entrepreneurship education is broad, but there are a large number of areas for improvement, in which universities can play an important role. In particular, this concerns elaborating and implementing a system for evaluating educational results, organizing monitoring of the effectiveness of such initiatives, including the analysis of success stories. In addition, a separate task is to expand the set of targeted programs for specific audiences (for example, unemployed), as well as to improve the content of such initiatives more deeply according to the specifics of the relevant target groups (for example, young mothers or older people).

Fifteen Years of Right to Information Act in India: A Long Way to Go

The passing & enactment of Right to Information Act, 2005 in India has been rightly considered as a milestone in the evolution of Indian Parliamentary Democracy which attempted to ensure transparency & good governance at the grass root levels by making the public authorities accountable & responsible. This Act liberated the harassed commoners who now had a very potent weapon to seek information which had hitherto remained suppressed in the dusty files of Babus (Bureaucrats) under the garb of official secrecy & confidentiality. However, in spite of many initial success stories over a period of time this Right to Information act has been losing its effectiveness & potency as it has failed to adopt the dynamism of complex Socio-Political realities. This paper attempts to give an overview & explain the history of RTI in India, its present status, limitations/drawbacks /challenges & and suggests some remedial measures to ensure its relevance in the rapidly transforming geo political context.

Mediatizing Slum Relocation in Egypt: Between Legitimization and Stigmatization

In Egypt, the relocation of residents of informal areas of housing into “proper” living environments is presented as a major political achievement offering citizens a much-improved quality of life. Therefore, it is not surprising that, following the Arab Uprisings, the current regime is widely publicizing relocation projects as success stories on TV and social media. As a way of garnering legitimization and securing stability, this official representation is reshaping the residents’ urban life and evoking narratives of slum dwellers’ transformation into respected citizens. Tackling a new area of interdisciplinary research between urban studies and media and communication studies, this article investigates the portrayal in mainstream media channels and social media platforms of two relocation projects (Al-Asmarat in Cairo and Al-Max in Alexandria), contrasting them with the residents’ perceptions of their new homes and their efforts to produce counter-imagery. The authors argue that both the state-dominated representation of the Al-Asmarat resettlement as an ideal solution to the crisis of informal settlements, as well as the more bottom-up construction of the Al-Max community as a picturesque fishing community, do not reflect the material experience of the inhabitants—despite it being presented as such in nationwide reporting. The effective centering of the public debate around the mediatized images has thus deflected criticism and enabled urban development projects to be positioned to legitimize the current rule despite the shortcomings of their implementation.

OptDesign: Identifying Optimum Design Strategies in Strain Engineering for Biochemical Production

Computational tools have been widely adopted for strain optimisation in metabolic engineering, contributing to numerous success stories of producing industrially relevant biochemicals. However, most of these tools focus on single metabolic intervention strategies (either gene/reaction knockout or amplification alone) and rely on hypothetical optimality principles (e.g., maximisation of growth) and precise gene expression (e.g., fold changes) for phenotype prediction. This paper introduces OptDesign, a new two-step strain design strategy. In the first step, OptDesign selects regulation candidates that have a noticeable flux difference between the wild type and production strains. In the second step, it computes optimal design strategies with limited manipulations (combining regulation and knockout) leading to high biochemical production. The usefulness 1and capabilities of OptDesign are demonstrated for the production of three biochemicals in E. coli using the latest genome-scale metabolic model iML1515, showing highly consistent results with previous studies while suggesting new manipulations to boost strain performance. Source code is available at https://github.com/chang88ye/OptDesign.