The Potential Application of Moringa oleifera Leaves in Functional Herbal Beverages: A Review of its Nutritional, Medicinal and Toxicity Profiles.

2020 ◽  
Vol 16 ◽  
Author(s):  
Yvonne Bailey-Shaw ◽  
Shawntae Rodney ◽  
Channtal Golding ◽  
Shadae Foster ◽  
Melaine Randle ◽  
...  
Keyword(s):  
Moringa Oleifera ◽  
Nutritive Value ◽  
Therapeutic Potential ◽  
Scientific Evidence ◽  
Journal Articles ◽  
Leaf Extracts ◽  
Moringa Oleifera Leaves ◽  
The Subject ◽  
Medicinal Properties ◽  
Moringa Oleifera Lam

: In recent times, Moringa oleifera Lam. has become one of the most sought after therapeutic cure-all plants in tropical and subtropical zones, including Jamaica. Anecdotally, the most popular choice of Moringa consumption locally is in the form of functional herbal beverages such as teas and juices, prepared from the leaves of the plant. However, there is little or no scientific evidence to validate the efficacy and or safety of such beverages. An extensive search of scientific literature published over the last decade (2010-2020) related to the nutritional, medicinal and toxicological profiles of Moringa oleifera was therefore conducted, with special emphasis on literature related to the dried leaves and aqueous leaf extracts thereof. Google Scholar, Science Direct and PubMed databases were the main search tools employed. Articles which referred to varieties of Moringa, other than oleifera were excluded from the searches, as were articles which referred to subject matters outside of nutrition, medicinal properties and toxicity. All peer-reviewed journal articles, and other online articles, which referred to the subject matters of interest were critically read and included in the review. This review is a compilation of evidence-based literature, indicating the outstanding nutritive value, high therapeutic potential and the relatively non-toxic properties of the dried leaves and aqueous leaf extracts of Moringa oleifera. Prospects for their application in the development of safe and efficacious functional herbal beverages are indicated.

scholarly journals Effect of aqueous extract of Moringa oleifera leaves on pharmacological models of epilepsy and anxiety in mice

2016 ◽  
Vol 03 (01) ◽  
pp. 012-019 ◽  
Author(s):  
Suvarna Ingale ◽  
Foram Gandhi
Keyword(s):  
Aqueous Extract ◽  
Moringa Oleifera ◽  
Scientific Evidence ◽  
Antiepileptic Activity ◽  
Board Test ◽  
Plus Maze ◽  
Moringa Oleifera Leaves ◽  
Hole Board ◽  
Hole Board Test ◽  
Moringa Oleifera Lam

Abstract Objective Among the psychiatric co-morbidities in epilepsy, anxiety disorders are highly frequent and have profound influence on the quality of life of epilepsy patients. Moringa oleifera Lam. (Moringaceae) is used in traditional medicine to treat various ailments including anxiety and epilepsy. However, no scientific evidence exists to support its use. We studied antiepileptic and anxiolytic activities of aqueous extract of Moringa oleifera Lam. leaves (AEMO). Methods Antiepileptic activity was evaluated using pentylenetetrazole (PTZ) induced seizure and maximum electroshock (MES) induced seizure test and anxiolytic activity was evaluated using elevated plus maze, light/dark box and hole board test. Results In present study, AEMO (250, 375 and 500 mg/kg, i.p.) demonstrated significant antiepileptic and anxiolytic effects. To study involvement of GABA in anxiolytic and antiepileptic activity of AEMO, we also evaluated effect of AEMO on Baclofen induced catatonia, a GABA mediated behavior, wherein AEMO significantly potentiated (preponed) baclofen induced catatonia, which is suggestive of its GABA mimetic action. Conclusion Thus, it may be concluded that aqueous extract of M. oleifera possess anxiolytic and antiepileptic effects possibly mediated via of GABA mimetic action and these findings authenticate the traditional claims about use of Moringa oleifera in treatment of epilepsy and anxiety.

scholarly journals Antimicrobial activity of Moringa oleifera: A short review

2020 ◽  
Vol 12 (1) ◽  
pp. 128-132
Author(s):  
I.A. Raubilu ◽  
U. Isah ◽  
M.A. Ahmad
Keyword(s):  
Antimicrobial Activity ◽  
Middle East ◽  
Key Words ◽  
Large Scale ◽  
Moringa Oleifera ◽  
Short Review ◽  
Medicinal Properties ◽  
Pathogenic Microbes ◽  
Potential Use ◽  
Moringa Oleifera Lam

Moringa oleifera Lam. (Family Moringaceae) is well – known for its various medicinal properties. It grows wild in the tropical and subtropical areas of Asia, Africa and the Middle East. In Nigeria, Moringa oleifera trees are planted at a large scale especially in the northern part of the country. It has been widely used in the treatment of certain diseases as a traditional medicinal herb. Antimicrobial activity is the most studied property of Moringa oleifera. Many studies have shown that nearly all types of Moringa oleifera tissues exhibit antimicrobial activity including antibacterial, antifungal, antiviral and anti parasitic property. This review describes progress on research conducted to understand the antimicrobial activity of Moringa oleifera and discusses the potential use of Moringa oleifera in the control of pathogenic microbes. Key words: Antimicrobial activity; Moringa oleifera; pathogenic microbes, control.  

scholarly journals How Functional Is Moringa oleifera? A Review of Its Nutritive, Medicinal, and Socioeconomic Potential

2017 ◽  
Vol 39 (1) ◽  
pp. 149-170 ◽  
Author(s):  
Oluwadara Oluwaseun Alegbeleye
Keyword(s):  
Moringa Oleifera ◽  
Therapeutic Potential ◽  
Scientific Evidence ◽  
Popular Literature ◽  
Scientific Data ◽  
Personal Health ◽  
Health Food ◽  
Self Medication ◽  
Developing Regions ◽  
Dietary Consumption

Moringa oleifera is an important tropical food plant that seems to have great nutritional, therapeutic, industrial, agricultural, and socioeconomic value. Dietary consumption of its parts and preparations is encouraged by several organizations, health food enthusiasts, and other specialists as a strategy of personal health preservation and self-medication in the treatment of various diseases. Studies extoling its ability to mitigate various degenerative ailments now exist in both the scientific and the popular literature. At face value, and considering the volume of reports available, much of this enthusiasm seems to be indeed justified. However, it is imperative to distinguish rigorous scientific evidence from anecdote. To achieve this, relevant experimental and review articles were sought and read critically to identify recent patterns and trends on this subject matter. Studies on the medicinal and functional properties of M. oleifera are available from various parts of the world, especially developing regions. Attempts have been made to parse the contemporary scientific data available supporting the claims regarding the phytochemical, nutritive, medicinal, environmental, agricultural, and socioeconomic capabilities of this plant. Studies reviewed provide compelling, albeit preliminary experimental evidence of therapeutic potential of the plant. It is important that M. oleifera products and preparations be properly chemically characterized and standardized before being administered.

scholarly journals Moringa oleifera Lam.: A Biofunctional Edible Plant from India, Phytochemistry and Medicinal Properties

2019 ◽  
Vol 8 (1) ◽  
pp. 10 ◽  
Author(s):  
V. N. Pandey ◽  
Vandana Chauhan ◽  
V. S. Pandey ◽  
P. P. Upadhyaya ◽  
Olga R. Kopp
Keyword(s):  
Nutritional Value ◽  
Moringa Oleifera ◽  
Industrial Applications ◽  
Edible Plant ◽  
Medicinal Value ◽  
Form Part ◽  
Medicinal Properties ◽  
Common Illnesses ◽  
Almost All ◽  
Moringa Oleifera Lam

Moringa oleifera is a versatile horticulture tree with important medicinal, nutritional and industrial applications, widely distributed and used in India. The Moringa tree originated in India and was introduced to Africa from India and other countries as a health supplement. Almost all parts of the plant have shown nutritional value and are used in India for a variety of food preparations. In India, M. oleifera leaves are available in powder to treat mild malnourishment in children. About all parts like leaves, seeds and pods are used as vegetables. Phytochemicals such as flavonoids, tannins, triterpenoids, saponins, flavonoids, anthraquinones, alkaloids and others, are responsible for the medicinal value of this plant. This species is rich in protein, fatty acids, vitamins and minerals that form part of its quality as superfood. It has been reported to have strong antimicrobial, antioxidant, anti-inflammatory, hepatoprotective, diuretic, anthelminthic and antiurolithiatic properties, among others. People in India use this species to treat common illnesses because of its availability and easy preparation. This review provides information on the significant potential of Moringa and its nutritional, medicinal, pharmaceutical and industrial values.

scholarly journals Studies on Analysis of Antioxidant and Enzyme Inhibitory Activity of Vitex negundo Linn.

2017 ◽  
Vol 9 (6) ◽  
Author(s):  
Ved Prakash ◽  
Shelly Rana ◽  
Anand Sagar
Keyword(s):  
Urease Activity ◽  
Therapeutic Potential ◽  
Radical Scavenging Activity ◽  
Scientific Evidence ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Vitex Negundo ◽  
Leaf Extracts ◽  
Treatment Of Obesity ◽  
Dpph Radical Scavenging

The current study was designed to investigate the leaf extracts of Vitex negundo Linn. for their antioxidant and enzyme inhibitory (α-amylae and urease) activity. The antioxidant capacity of the different extracts (methanol, acetone and aqueous) of this plant was evaluated by DPPH (1,1-diphenyl-2-picrylhydrazyl) and reducing power tests. The plant exhibited good DPPH radical scavenging activity and moderate reducing power potential Further, all the extracts of V. negundo were reported to possess good anti-alpha amylase and anti-urease activity of greater than 50% in all the solvents used at a concentration of 1 mg/mL. Thus the study provided scientific evidence to the traditional uses of this plant in the treatment of obesity, diabetes, ulcers, kidney stones etc. Therefore, the leaf extracts of this plant can be selected for further investigation to determine their therapeutic potential.

scholarly journals The effect of 2-hydroxypropyl β-cyclodextrin on the stability of polyphenolic compounds from Moringa oleifera Lam leaf extracts in a natural low-transition temperature mixture

2018 ◽  
Vol 17 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Ioanna Karageorgou ◽  
Spyros Grigorakis ◽  
Stavros Lalas ◽  
Dimitris P. Makris
Keyword(s):  
Transition Temperature ◽  
Moringa Oleifera ◽  
Protective Action ◽  
Leaf Extracts ◽  
Decay Constants ◽  
Slowing Down ◽  
First Order Kinetics ◽  
Quercetin Glycosides ◽  
The Stability ◽  
Moringa Oleifera Lam

Abstract Polyphenol extracts from Moringa oleifera leaves (MoL) were obtained with a glycerol-based low-transition temperature mixture (LTTM) and a combination of LTTM with 2-hydroxypropyl β-cyclodextrin (HP-β-CD). The extracts were maintained at 4, 22 and 50 °C for 18 days and the antiradical activity (AAR) was recorded to detect modifications in the antioxidant activity of the extracts. AAR displayed a constant decline at every temperature tested, following pseudo first-order kinetics and the decay constants suggested that the presence of HP-β-CD had a protective action, slowing down AAR decline. The analysis of the polyphenolic profiles using liquid chromatography-diode array-mass spectrometry revealed that after storage for 18 days at 50 °C, the major quercetin glycosides occurring in MoL were extensively degraded. Based on the detection of protocatechuic acid in the stored extracts, putative pathways of flavonol glycoside degradation were proposed. It was concluded that the decomposition of these components was mainly responsible for the AAR decline observed.

scholarly journals Phytochemical Analyses, Antioxidant and Anticancer Activities of Ethanolic Leaf Extracts of Moringa oleifera Lam. Varieties

Plants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2348
Author(s):  
Bilques Farooq ◽  
Bhupendra Koul ◽  
Deveshi Mahant ◽  
Dhananjay Yadav
Keyword(s):  
Antioxidant Activity ◽  
Moringa Oleifera ◽  
Sugar Content ◽  
Soluble Proteins ◽  
Mature Stage ◽  
Cytotoxic Activities ◽  
Anticancer Activities ◽  
Leaf Extracts ◽  
Anticancer Compounds ◽  
Moringa Oleifera Lam

Moringa oleifera Lam. (Moringaceae) is revered as s ‘miracle tree’ due to its remarkable nutritional, medicinal and industrial uses. In our study, a comparative analysis of the nutritional parameters (antioxidant activity, sugar content—TSS, total soluble proteins—TSP and mineral contents), phytochemicals (HPLC analysis of four anticancer compounds), and cytotoxicity of M. oleifera leaf extracts (MLEs) of five selected varieties (conventional, PKM-1, PKM-2, ODC, and Jaffna), was performed. Jaffna variety possessed the highest antioxidant activity (FRAP) followed by other four varieties. The trend observed was: Jaffna (9.47 µg/mL, 18.48 µg/mL, 29.39 µg/mL, and 35.37 µg/mL) > PKM-1 (4.82 µg/mL, 7.63 µg/mL, 22.33 µg/mL, and 27.71 µg/mL) > PKM-2 (2.10 µg/mL, 7.04 µg/mL, 13.18 µg/mL, and 21.78 µg/mL) > ODC (0.17 µg/mL, 2.10 µg/mL, 4.41 µg/mL and 13.94 µg/mL) > Conventional (0.05 µg/mL, 1.08 µg/mL, 2.86 µg/mL, and 5.40 µg/mL), total soluble proteins (TSP) [0.69 ± 0.01 and 0.94 ± 0.01 µg/mL (young and mature stage, respectively)], sugar content (TSS) [0.39 ± 0.01 and 0.51 ± 0.01 µg/mL (young and mature stage, respectively)], chlorophyll content [1.07 ± 0.01 (plantlet stage), 1.36 ± 0.003 (vegetative-stage), 0.82 ± 0.004 (reproductive stage) mg/g], followed by the other four varieties. The trend observed for cytotoxic activities of ethanolic MLEs on HepG2 cell line, based on the IC50 values, was conventional (1.22 mg/mL) > ODC (0.90 mg/mL) > PKM-2 (0.65 mg/mL) > PKM-1 (0.35 mg/mL) > Jaffna (0.15 mg/mL). The results of HPLC quantification of anticancer compounds [beta-sitosterol (0.244%), quercetin (0.216%), kaempferol (0.013%), and moringin (0.063%)] was also in consonance with that of MTT assay. In summary, the trend observed in all the parameters tested was Jaffna > PKM-1 > PKM-2 > ODC > conventional. Thus, Jaffna variety has a better potential to combat malnutrition and cancer and must be recommended for commercial plantations.

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