scholarly journals Resin Infiltration into Differentially Extended Experimental Carious Lesions

2014 ◽  
Vol 8 (1) ◽  
pp. 251-256 ◽  
Author(s):  
Wolfgang H Arnold ◽  
Lena Bachstaedter ◽  
Korbinian Benz ◽  
Ella A Naumova

Resin infiltration of initial caries lesions is a novel method of caries therapy. However, it has some limitations. Therefore, further experimental studies are needed to improve resin infiltration. It was the aim of this investigation to study resin infiltra-tion into different experimental carious lesions. Caries-free extracted human molars and premolars were demineralized for 3, 6, 9 and 12 days and infiltrated with resin. Prior to infiltration, the teeth were incubated with sodium fluorescein. After em-bedding, serial sections were cut through the experimental lesions, and the penetration of the resin was measured with fluo-rescence microscopy. Two infiltrated teeth from each time interval were not embedded and cut. Infiltration of the resin was then studied with EDS element analysis. The results showed that with increasing demineralization time, the lesion expansion was also increasing, and the resin infiltration was always almost complete. From these results it can be concluded that artifi-cial standardized caries-like lesions are suitable for experimental studies of resin infiltration.

2011 ◽  
Vol 58 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Tatjana Savic-Stankovic ◽  
Milica Jovanovic-Medojevic ◽  
Slavoljub Zivkovic

Introduction. Dental status of most people with special needs is not satisfactory. Many of them are edentulous or toothless, with acute extensive caries lesions present, high DMFT index and severe periodontal disease. The objective of this study was to examine the dental status of mentally impaired persons who live in the special institution ?Srce u jabuci? in Pancevo. Material and Methods. Clinical examination was performed on 114 institutionalized patients (68 male and 46 female), age 22 to 71 years. Patients were divided in two groups; the first group consisted of 71 persons who had a moderate mental disorder (F71), while the second group included 43 respondents with severe mental retardation (F72). Oral examination revealed: the number of present teeth, caries lesions, the presence of restorations, the number of extracted teeth, the presence of residual roots, fractures and the presence and number of fixed restorations. Results. The mean DMFT of total examined teeth was 20.33?7.63. The greatest percentage found for extracted teeth (63.76%): in the first group 63.23%, and in the second 64.06%. The percentage of teeth that had caries lesions of all examined teeth was 33.48%, while the lowest percentage was for restored teeth (2.76%). In majority of examined people, initial caries, deep caries, or tooth with the exposed pulp (K1 - 51.74% K2 - 40.35%, K3 - 51.75%) were not found. A high percentage of examined people had more than 10 extracted teeth (52.63%). Most of them did not have any restoration in the mouth (81%) and only three persons had fixed denture. Conclusion. Dental status of institutionalized mentally impaired persons showed high prevalence of extracted teeth, significant presence of carious lesions and small percentage of restored teeth with inadequate oral hygiene.


Author(s):  
V. Melnik ◽  
L. Gorzov ◽  
S. Melnik ◽  
Ya. Duganchik

Introduction. The largest amount of information about the dental caries is provided by the International Caries Detection and Assessment II system (ICDAS II), which is known as evidence-based approach to clinical visual detection of dental caries and enables to detect the stage and depth of carious lesions from the slightest changes in dental enamel to visible cavities affecting dentin. This system has been developed by the group of leading experts in the field of cariology. The results obtained by determining the ICDAS II index contribute to making right clinical decision in the choice of prevention and treatment methods, as well as to predicting the carious progression. The aim of the study is to assess the prevalence and intensity of initial dental caries in people using the ICDAS II index. Materials and methods. A total of 32 patients aged 12 to 25 years were examined. During the dental examination, we assessed the prevalence of dental caries using the ICDAS II. Clinical findings were recorded in oral follow-up charts proposed by the ICDAS Foundation for Epidemiological Studies, which allow us to record dental hard tissue status using six codes: three for assessing carious changes in enamel and three for assessing carious changes in dentine in a sequence of growing severity. Statistical processing of the findings was performed using Student's t-test. Results. Carious lesions were detected in all study participants, their total number was 285, of which 140 (49.1%) had the code 1 and 145 (50.8%) had the code 2 according to the ICDAS II. On average, each of the participants had 9.28 ± 0.67 foci of enamel demineralization. The average number of lesions with codes 1 and 2 by the ICDAS II was respectively 4.54 ± 0.51 and 4.74 ± 0.38 (p> 0.05). The average intensity of dental caries increased with age from 8.29 ± 0.83 in 12-15 year old individuals to 9.39 ± 1.20 in 18-25 year old individuals (p> 0.05), mainly by the growth of the average number of the mean number of caries lesions with the code 1 according to the ICDAS II. Mostly carious lesions are found on the masticatory surfaces, their total number made up 159 (55.7%). 101 (35.4%) caries lesions were found on the vestibular and oral parts of the tooth surfaces, and 25 (8.9%) average lesions were detected on the proximal surfaces. The average intensity of caries detected on the chewing surfaces of the teeth was 5.15 ± 0.49 and was significantly higher than on the vestibular and oral (3.33 ± 0.57, p <0.05) and proximal (0.79 ± 0, 20, p <0.001) surfaces. Conclusion. The obtained results showed a high intensity of carious lesions, with their predominance in the active stages in the two age groups under the study. This proves the appropriateness of using diagnostic ICDAS criteria for early detection of initial caries and its proper treatment.


2021 ◽  
Author(s):  
Seok-Woo Park ◽  
Si-Mook Kang ◽  
Hyung-Suk Lee ◽  
Sang-Kyeom Kim ◽  
Eun-Song Lee ◽  
...  

Abstract We aimed to determine whether dye-ehanced quantitative light-induced fluorescence (DEQLF), wherein the porous structure of carious lesions is filled in with a fluorescent dye, can be used to quantitatively and intuitively distinguish between active and inactive carious lesions. To simulate active and inactive caries, lesions were artificially formed on 126 bovine specimens. They were demineralized with 1% carbopol solution for 3 (A3), 5 (A5), and 10 days (A10). Half the specimens in each group were remineralized with 2% NaF (I3, I5, and I10). The specimens were dehydrated for 10 s and dyed with 100-µM sodium fluorescein for 10 s. Images were captured with a QLF-digital 2+ Biluminator. Fluorescence intensity of the lesions (ΔG) between the groups and absolute changes in ΔG (|ΔΔG|) between dehydration and dye penetration were compared using the independent t-test. ΔG in A3, A5, and A10 were higher than those in I3, I5, and I10 (P<0.001). In |ΔΔG| comparisons, dye penetration was 3.1-3.7 times higher than dehydration in the active group (P<0.001), and was 1.7-2.2 times lower than dehydration in I3 and I5 (P<0.05), with no significant difference in I10. DEQLF may be used to clinically evaluate early caries activity, and longitudnally monitor changes in lesion activity.


2020 ◽  
Vol 25 (1) ◽  
Author(s):  
Swietłana Kozaczuk

The use of fluoride, a healthy diet and good dental care habits are the pillars of the fight against caries. At a time when the anti-fluoride movement is on the increase and raises doubts even amongst the dentists and dental hygienists, the dental environment should be based on the credible scientific evidence regarding the effectiveness and safety of therapy in their clinical management. The article presents the clinical cases in which the agent for deep penetration fluoridation Tiefenfluorid® junior (Humanchemie, German) was used in the treatment and prevention of carious lesions in children. The visual-tactile method was used for detecting caries lesions. The International Caries Detection and Assessment System – ICDAS II was used for classifying dental caries. Carious lesions activity were assessed using visual-tactile method at control visits every 3 months within 12 months. Fluoride is effective in the treatment of initial caries in enamel, and the agent based on silver and fluorine SDF (Silver Diamine Fluoride) effectively inhibits tooth decay in the dentin. The disadvantage of SDF is the black color of the teeth. In contrast to common fluoride compounds, the solution with fluoride Tiefenfluorid® junior (Humanchemie, German) becomes non-toxic due to the reaction with the second application solution with calcium hydroxide. Furthermore, the process takes place deep in the funnels of the dental enamel, not on the tooth surface. The deep penetration fluoridation can be used for the caries prophylaxis, including the mineral fissure sealing, as well as for the treatment of initial caries lesions. In the treatment of initial caries in small children, it is an alternative to the silver nitrate impregnation and for the fluoride varnishes.


2016 ◽  
Vol 7 (2) ◽  
Author(s):  
Marija Obradović ◽  
Olivera Dolić ◽  
Slava Sukara ◽  
Jovan Vojinović

Objective: The aim of this study was to examine the impact of fluoride varnish and a new generation of nanoapatite varnish containing both Casein PhosphoPeptide − Amorphous Calcium Phosphate (CPP-ACP) and fluoride, on the activity of the initial smooth surface caries lesions of primary teeth. Materials and Methods: A randomized clinical trial was conducted on a total of 120 primary teeth with initial caries lesions in enamel, at children under the age of 24 months. Clinical evaluation of initial carious lesions and its evaluation during the research was carried out using the International Caries Detection and Assessment System (ICDAS-II). Results: There was a change of activity of the carious lesion in all three groups (CPP-ACPFG, FG and KG) during the time of treatment and follow-up, which was statistically significant. However, in the group of CPP-ACPFG, there was a better result compared to the FG and КG. Conclusion: Remineralizing treatment of new generation varnish containing both nanoapatite and fluоride gave a better result compared to conventional varnish with fluoride.


2017 ◽  
Vol 68 (11) ◽  
pp. 2588-2592
Author(s):  
Ruxandra Sava Rosianu ◽  
Angela Codruta Podariu ◽  
Meda Lavinia Negrutiu ◽  
Camelia Szuhanek ◽  
Cosmin Sinescu

Resin infiltration is considered a treatment option for initial caries lesions. To prevent enamel lesion s from further demineralization a complete and homogeneous penetration of low-viscosity resins should be accomplished. The aim of this study was to compare the penetration abilities of 3 commercial products: Icon (DMG, Germany), Fluorodose (Centrix Inc. USA) and Tetric flow (IvoclarVivadent, Schaan, Liechtenstein).Artificial white spot lesions were produced in 60 orthodontic extracted human premolars. The samples were randomly divided into 3 groups: F - weeklyapplication of 5%fluoride gel; IC � resin infiltration (Icon1-DMG) and T - treatment with composite resins (Tetric flow). Specimens were studied using confocal microscopy and penetration depths were determined. A good correlation between PC and penetration depth was thereby observed (Pearson correlation coefficient, r=0.820).


2021 ◽  
Vol 20 ◽  
pp. e219022
Author(s):  
Priscila Regis Pedreira ◽  
Janaina Emanuela Damasceno ◽  
Ana Ferreira Souza ◽  
Gabriela Alves de Cerqueira ◽  
Flávio Henrique Baggio Aguiar ◽  
...  

Minimally invasive dentistry is based on conservative techniques for the treatment of initial caries lesions, the so-called white spot lesions. One of the conservative maneuvers includes the use of enamel resin infiltrant: a low viscosity material that penetrates the enamel pores to stop lesion progression. Aim: Therefore, this case report aimed to describe the clinical case of a 28-year-old female patient under routine consultation, in which a radiographic examination showed the presence of two incipient caries lesions in the left upper premolars. Methods: The application of a resin infiltrating agent (Icon®, DMG – Hamburg, Germany) was chosen as treatment to stop caries lesions progression. Conclusion: The use of this conservative technique can be considered a promising approach for the prevention of dental tissue wear, and the resin infiltrant is considered an effective material.


2016 ◽  
Vol 10 (1) ◽  
pp. 505-515 ◽  
Author(s):  
Wolfgang H. Arnold ◽  
Ann-Kathrin Meyer ◽  
Ella A. Naumova

Background:Low viscosity resin infiltration of initial caries lesions is a modern microinvasive method to treat initial cries lesions. However, only scarce information is available about the long-term surface alterations of infiltrated lesions.Methods:Twenty-eight premolar teeth exhibiting non-cavitated initial caries lesions (International Caries Detection and Assessment System (ICDAS code 1&2)) were divided into two groups, one of which was infiltrated with resin, and the other remained untreated. The teeth underwent two thermocycling procedures. The surface roughness was determined quantitatively, and the results were evaluated statistically. In addition, the surfaces of the lesions were investigated by scanning electron microscopy (SEM), and the surface was analyzed visually with respect to surface irregularities.Results:The results showed a reduction in the surface roughness that was significant after 2500 thermocycles compared to the untreated surface. In the control specimens, no change in the surface roughness was found. The qualitative SEM data also showed a smooth surface after thermocycling, which supported the statistical findings.Conclusion:After thermocycling, resin-infiltrated enamel surfaces become smoother and had no additional risk for plaque accumulation.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Saurabhi Samant ◽  
Wei Wu ◽  
Shijia Zhao ◽  
Behram Khan ◽  
Mohammadali Sharzehee ◽  
...  

AbstractLeft main (LM) coronary artery bifurcation stenting is a challenging topic due to the distinct anatomy and wall structure of LM. In this work, we investigated computationally and experimentally the mechanical performance of a novel everolimus-eluting stent (SYNERGY MEGATRON) purpose-built for interventions to large proximal coronary segments, including LM. MEGATRON stent has been purposefully designed to sustain its structural integrity at higher expansion diameters and to provide optimal lumen coverage. Four patient-specific LM geometries were 3D reconstructed and stented computationally with finite element analysis in a well-validated computational stent simulation platform under different homogeneous and heterogeneous plaque conditions. Four different everolimus-eluting stent designs (9-peak prototype MEGATRON, 10-peak prototype MEGATRON, 12-peak MEGATRON, and SYNERGY) were deployed computationally in all bifurcation geometries at three different diameters (i.e., 3.5, 4.5, and 5.0 mm). The stent designs were also expanded experimentally from 3.5 to 5.0 mm (blind analysis). Stent morphometric and biomechanical indices were calculated in the computational and experimental studies. In the computational studies the 12-peak MEGATRON exhibited significantly greater expansion, better scaffolding, smaller vessel prolapse, and greater radial strength (expressed as normalized hoop force) than the 9-peak MEGATRON, 10-peak MEGATRON, or SYNERGY (p < 0.05). Larger stent expansion diameters had significantly better radial strength and worse scaffolding than smaller stent diameters (p < 0.001). Computational stenting showed comparable scaffolding and radial strength with experimental stenting. 12-peak MEGATRON exhibited better mechanical performance than the 9-peak MEGATRON, 10-peak MEGATRON, or SYNERGY. Patient-specific computational LM stenting simulations can accurately reproduce experimental stent testing, providing an attractive framework for cost- and time-effective stent research and development.


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