scholarly journals Iota-Carrageenan as an Antiviral Treatment for the Common Cold

2020 ◽  
Vol 14 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Ronald Eccles
Keyword(s):  
Clinical Trials ◽  
Respiratory Tract ◽  
Common Cold ◽  
Antiviral Treatment ◽  
Respiratory Viruses ◽  
Common Disease ◽  
Upper Respiratory Tract ◽  
Good Tolerability ◽  
The Common ◽  
Positively Charged

Introduction: The common cold syndrome of acute upper respiratory tract viral infection is the most common disease among mankind and is an extremely common illness in children. There is a great need for a safe and effective antiviral treatment with minimal side effects. The challenge in developing a treatment is the numerous and varied respiratory viruses that cause this common illness and the need for a treatment with good tolerability and safety. Explanation: All respiratory viruses must reach the cell surface by passing through respiratory fluid and mucus, and this common feature may allow for the development of antivirals that capture viruses during this transit. This article discusses how large polyanionic molecules such as iota-carrageenan may trap positively charged respiratory viruses. Iota-carrageenan is a large polysaccharide molecule which is neither absorbed from the respiratory tract nor metabolised. It, therefore, does not have any pharmacological properties. Iota-carrageenan nasal spray has been shown to reduce the titres of respiratory viruses and to reduce the severity of symptoms in placebo-controlled clinical trials, including children and adults. The results of four clinical trials are presented. Conclusion: Iota-carrageenan is a good candidate as a safe and effective non-specific antiviral treatment for common cold, and more research is justified on polyanionic molecules like carrageenans as antivirals.

Respiratory viruses

2011 ◽  
pp. 208-211
Author(s):  
Dr Mark Harrison
Keyword(s):  
Respiratory Syncytial Virus ◽  
Respiratory Tract ◽  
Common Cold ◽  
Respiratory Viruses ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
The Common ◽  
Upper Respiratory ◽  
Syncytial Virus ◽  
Tract Infections

15.1 Rhinovirus, 209 15.2 Influenza, 210 15.3 Parainfluenza, 211 15.4 Respiratory syncytial virus (RSV), 211 • There are more than 100 different serotypes of rhinovirus. • Rhinovirus is chiefly limited to upper respiratory tract infections and is the major cause of the common cold....

scholarly journals Animal Coronaviruses and SARS-COV-2 in Animals, What Do We Actually Know?

Life ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 123
Author(s):  
Paolo Bonilauri ◽  
Gianluca Rugna
Keyword(s):  
Veterinary Medicine ◽  
Respiratory Tract ◽  
Common Cold ◽  
Domestic Animals ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
The Common ◽  
Upper Respiratory

Coronaviruses (CoVs) are a well-known group of viruses in veterinary medicine. We currently know four genera of Coronavirus, alfa, beta, gamma, and delta. Wild, farmed, and pet animals are infected with CoVs belonging to all four genera. Seven human respiratory coronaviruses have still been identified, four of which cause upper-respiratory-tract diseases, specifically, the common cold, and the last three that have emerged cause severe acute respiratory syndromes, SARS-CoV-1, MERS-CoV, and SARS-CoV-2. In this review we briefly describe animal coronaviruses and what we actually know about SARS-CoV-2 infection in farm and domestic animals.

scholarly journals THE PROTECTION AFFORDED BY VACCINATION AGAINST SECONDARY INVADERS DURING COLDS IN INFANCY

1934 ◽  
Vol 60 (5) ◽  
pp. 655-660 ◽  
Author(s):  
Yale Kneeland
Keyword(s):  
Respiratory Tract ◽  
Respiratory Disease ◽  
Common Cold ◽  
Pathogenic Bacteria ◽  
Upper Respiratory Tract ◽  
The Common ◽  
Upper Respiratory ◽  
Intensive Course

All intensive course of vaccination with the pathogenic bacteria of the upper respiratory tract modified favorably the winter outbreak of severe respiratory disease in an infant population. The incidence of the common cold was not affected. The significance of these findings is discussed.

scholarly journals STUDIES IN THE COMMON COLD

1928 ◽  
Vol 47 (2) ◽  
pp. 193-206 ◽  
Author(s):  
Katherine C. Mills ◽  
G. S. Shibley ◽  
A. R. Dochez
Keyword(s):  
Respiratory Tract ◽  
Common Cold ◽  
General Character ◽  
Upper Respiratory Tract ◽  
Normal Flora ◽  
Gram Negative ◽  
The Common ◽  
Upper Respiratory

1. A study of the Gram-negative, filter-passing, anaerobic organisms, described by Olitsky and Gates, and Gates and McCartney, has been undertaken with a view to determining their general character and their possible rôle in the causation of the common cold. 2. These organisms seem to constitute part of the normal flora of the upper respiratory tract and would seem to bear no etiological relationship to the common cold.

scholarly journals STUDIES ON THE COMMON COLD

1930 ◽  
Vol 51 (4) ◽  
pp. 617-624 ◽  
Author(s):  
Yale Kneeland
Keyword(s):  
Respiratory Tract ◽  
Common Cold ◽  
Secondary Infection ◽  
Upper Respiratory Tract ◽  
The Common ◽  
Upper Respiratory

1. The upper respiratory tract is sterile at birth. 2. In the first 2 weeks of life the infant acquires a basal flora comparable to that of adults except that the potential pathogens are absent. 3. During the ensuing months the potential pathogens may appear without giving rise to symptoms and by 8 months the infant's flora is entirely comparable to the adult's. 4. There is no evidence of a specific bacterial incitant for the first colds of infancy. 5. In infants with recurrent colds, secondary infection of the nose with pneumococci or B. pfeifferi probably plays a part.

scholarly journals Animal Coronaviruses and SARS-COV-2 in animals, what do we actually know?

2021 ◽  
Author(s):  
Paolo Bonilauri ◽  
Gianluca Rugna
Keyword(s):  
Veterinary Medicine ◽  
Respiratory Tract ◽  
Common Cold ◽  
Domestic Animals ◽  
Respiratory Tract Diseases ◽  
Upper Respiratory Tract ◽  
The Common ◽  
Upper Respiratory

Coronaviruses (CoVs) are a well-known group of viruses in veterinary medicine. We currently know four genera of Coronavirus, alfa, beta, gamma and delta. Wild, farmed and pet animals are infected with CoVs belonging to all four genera. Seven human respiratory coronaviruses have still been identified, four of which cause upper respiratory tract diseases, specifically, the common cold, and the last three that have emerged cause severe acute respiratory syndromes, SARS-CoV-1, MERS-CoV and SARS-CoV-2. In this review we briefly describe animal coronaviruses and what we actually know about SARS-CoV-2 infection in farm and domestic animals.

NEWS AND ANNOUNCEMENTS

PEDIATRICS ◽  
1958 ◽  
Vol 22 (1) ◽  
pp. 179-186
Keyword(s):  
Influenza Virus ◽  
Respiratory Tract ◽  
Common Cold ◽  
Half Life ◽  
Respiratory Viruses ◽  
Atypical Pneumonia ◽  
The Common

Dr. Frank L. Horsfall reviewed the properties of the common respiratory viruses, namely the adenoviruses, influenza virus, atypical pneumonia virus and the common cold viruses. These viruses reside principally in the respiratory tract. It was interesting to learn that the influenza virus has a very brief half-life of only 1 to 2 hours in vitro. The common cold viruses do not produce antibodies or cause the development of immunity. None of this group of viruses are affected by antibiotics except the psittacosis virus.

scholarly journals Bias against Vitamin C in Mainstream Medicine: Examples from Trials of Vitamin C for Infections

Life ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 62
Author(s):  
Harri Hemilä ◽  
Elizabeth Chalker
Keyword(s):  
Clinical Trials ◽  
Vitamin C ◽  
Common Cold ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
The Third ◽  
Nutritional Recommendations ◽  
Mainstream Medicine ◽  
The Common ◽  
Based Medicine

Evidence has shown unambiguously that, in certain contexts, vitamin C is effective against the common cold. However, in mainstream medicine, the views on vitamin C and infections have been determined by eminence-based medicine rather than evidence-based medicine. The rejection of the demonstrated benefits of vitamin C is largely explained by three papers published in 1975—two published in JAMA and one in the American Journal of Medicine—all of which have been standard citations in textbooks of medicine and nutrition and in nutritional recommendations. Two of the papers were authored by Thomas Chalmers, an influential expert in clinical trials, and the third was authored by Paul Meier, a famous medical statistician. In this paper, we summarize several flaws in the three papers. In addition, we describe problems with two recent randomized trial reports published in JAMA which were presented in a way that misled readers. We also discuss shortcomings in three recent JAMA editorials on vitamin C. While most of our examples are from JAMA, it is not the only journal with apparent bias against vitamin C, but it illustrates the general views in mainstream medicine. We also consider potential explanations for the widespread bias against vitamin C.

scholarly journals Antibiotic prescription for under-fives with common cold or upper respiratory tract infection in Savannakhet Province, Lao PDR

2019 ◽  
Vol 47 (1) ◽  
Author(s):  
Bounxou Keohavong ◽  
Manithong Vonglokham ◽  
Bounfeng Phoummalaysith ◽  
Viengsakhone Louangpradith ◽  
Souphalak Inthaphatha ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Common Cold ◽  
Antibiotic Prescription ◽  
Lao Pdr ◽  
Upper Respiratory Tract Infection ◽  
Upper Respiratory Tract ◽  
Upper Respiratory
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