scholarly journals Molecular Basis of Self-(in)compatibility and Current Status of S-genotyping in Rosaceous Fruit Trees

2009 ◽  
Vol 78 (2) ◽  
pp. 137-157 ◽  
Author(s):  
Hisayo Yamane ◽  
Ryutaro Tao
2012 ◽  
Vol 21 (6) ◽  
pp. 1163-1181 ◽  
Author(s):  
Giorgio Gambino ◽  
Ivana Gribaudo

Cancers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3456 ◽  
Author(s):  
Lorenzo Pilla ◽  
Andrea Alberti ◽  
Pierluigi Di Mauro ◽  
Maria Gemelli ◽  
Viola Cogliati ◽  
...  

Advances in the genomic, molecular and immunological make-up of melanoma allowed the development of novel targeted therapy and of immunotherapy, leading to changes in the paradigm of therapeutic interventions and improvement of patients’ overall survival. Nevertheless, the mechanisms regulating either the responsiveness or the resistance of melanoma patients to therapies are still mostly unknown. The development of either the combinations or of the sequential treatment of different agents has been investigated but without a strongly molecularly motivated rationale. The need for robust biomarkers to predict patients’ responsiveness to defined therapies and for their stratification is still unmet. Progress in immunological assays and genomic techniques as long as improvement in designing and performing studies monitoring the expression of these markers along with the evolution of the disease allowed to identify candidate biomarkers. However, none of them achieved a definitive role in predicting patients’ clinical outcomes. Along this line, the cross-talk of melanoma cells with tumor microenvironment plays an important role in the evolution of the disease and needs to be considered in light of the role of predictive biomarkers. The overview of the relationship between the molecular basis of melanoma and targeted therapies is provided in this review, highlighting the benefit for clinical responses and the limitations. Moreover, the role of different candidate biomarkers is described together with the technical approaches for their identification. The provided evidence shows that progress has been achieved in understanding the molecular basis of melanoma and in designing advanced therapeutic strategies. Nevertheless, the molecular determinants of melanoma and their role as biomarkers predicting patients’ responsiveness to therapies warrant further investigation with the vision of developing more effective precision medicine.


1995 ◽  
pp. 419-420 ◽  
Author(s):  
S. Spiegel ◽  
A. Stein ◽  
Y. Tam
Keyword(s):  

2021 ◽  
Author(s):  
Shingo Toyoshima

Abstract C. sasakii is a pest of rosaceous fruits in eastern Asia, and does not spread easily to the non-native areas and countries. C. sasakii has the potential to fly long distances, but usually flies only within and between canopies of fruit trees. Aerial dispersal to non-native areas has not been recorded. International trade of rosaceous fruits is a possible cause of spread of C. sasakii, but it is difficult for it to enter non-native countries under quarantine inspection. Even if C. sasakii enters non-native countries by international trade, it is not easy to establish a population, probably because the larvae in fruits cannot find a cocooning site near rosaceous plants after escaping from the fruits. However, C. sasakii has a strong impact on the management of rosaceous fruit orchards once a population is established. Damage to fruits can reach 100% in some cases in pears [Pyrus spp.] and 40-100% in apples [Malus spp.] if not controlled.


Author(s):  
E. Knapp ◽  
V. Hanzer ◽  
D. Mendonça ◽  
A. da Câmara Machado ◽  
H. Katinger ◽  
...  

HortScience ◽  
1996 ◽  
Vol 31 (4) ◽  
pp. 684c-684
Author(s):  
J. Farias-Larios ◽  
S. Guzman-Gonzalez ◽  
A. Michel-Rosales

The productivity of marginal soils frequently found in the arid tropics might be improved by using VAM fungi as “biofertilizer” and as a tool of sustainable agricultural systems. Study of mycorrhizas of fruit trees was performed in 1987 in western Mexico. More progress has been made in resources, taxonomy, anatomy and morphology, physiology, ecology, effects, and application of mycorrhizas in fruit trees and ornamental plants production. Currently, five genera has been identified and inoculated plants showed significant difference in respect to plants not inoculated with mycorrhizal fungi. Citrus trees were highly dependent on mycorrhizae for normal growth and development, while the banana plants showed lower levels of root colonization by different strains of VAM fungi. The added endomycorrhizal inoculum significantly increased root fungal colonization in fruit trees and reduce the time in nursery. The current status and research trends in the study of fruit tree mycorrhizas in western Mexico are introduced, and the application prospects in sustainable agriculture also are discussed.


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