scholarly journals Vitamin D Status and its Association with Lipid Profile among Medical Undergraduates in a Medical College in Kerala

2020 ◽  
Vol 15 ◽  
pp. 7
Author(s):  
K. Annapurna ◽  
P. K. Swarnalatha
Keyword(s):  
Vitamin D ◽  
Lipid Profile ◽  
Vitamin D Deficiency ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Medication History ◽  
Chi Square ◽  
Cross Sectional ◽  
Medical Undergraduates ◽  
Chi Square Test

Objectives: To assess the vitamin D status among the study population and to determine the association between Vitamin D deficiency and dyslipidemia. Materials and Methods: This cross sectional study included medical undergraduates aged between 18-20 years with no major illness or medication history. Complete fasting lipid profile was measured by photometry method and biochemical estimation of serum 25-hydroxy 25(OH)D was done using automated chemiluminescent immunoassay. Vitamin D status and lipid profile parameters were compared using Pearson Chi-square test. P < 0.05 was considered as statistically significant. Descriptive statistics such as mean, standard deviation, and inferential statistics like Chi-square test were used. Results: 96.6% were vitamin D deficient and 40% of the subjects were dyslipidemic. There was no significant association between Vitamin D status and Lipid profile. Conclusion: High prevalence of Vitamin D deficiency but no significant association between vitamin D deficiency and dyslipidemia.

scholarly journals Vitamin D Status of Epileptic Children in India: A Prospective Cross-Sectional Study from a Tertiary Care Centre

2020 ◽  
Vol 10 (01) ◽  
pp. e87-e92
Author(s):  
Chandrika Azad ◽  
Vishal Guglani ◽  
Jasbinder Kaur ◽  
Roosy Aulakh ◽  
Sukhvinder Singh ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Epileptic Children ◽  
25 Oh Vitamin D

AbstractVitamin D deficiency is prevalent all over the world, especially in tropical countries. In epileptics, antiepileptic drugs (AED) and associated comorbidities further impact vitamin D status. The aim of this study is to estimate the prevalence of 25(OH) vitamin D deficiency in epileptic children and evaluate probable risk factors. A cross-sectional study of 200 children between 1 and 18 years of age on AED was undertaken in the pediatric neurology clinic of a tertiary care center of Northern India. In all children, serum 25(OH) vitamin D levels, calcium, phosphorus, and alkaline phosphatase were estimated. The deficiency levels of vitamin D were categorized as: deficiency <20 ng/mL, insufficiency 20 to 30 ng/mL, and sufficiency >30 ng/mL. The potential risk factors for hypovitaminosis D, including type of epilepsy, AED regimen (specific medications, polytherapy vs. monotherapy), cerebral palsy, ambulatory status, intellectual disability, body mass index, gender, and vegetarianism were examined. Among the 200 enrolled children (60% boys), 106/200 (53%) were vitamin D deficient. There was no significant relation of vitamin D levels with gender, type of epilepsy, neurological deficit, and type of AED. An inverse relationship of higher phenytoin doses during monotherapy associated with lower vitamin D levels in monotherapy was found, thereby suggesting adverse effect of high doses of phenytoin on vitamin D levels. VDD is common among epileptic children on AED therapy. Vitamin D deficiency is common prevalent among epileptic children on AED therapy, and its detection and treatment correction should be an integral part of epilepsy management.

scholarly journals Vitamin D status among adolescents in Kuwait: a cross-sectional study

BMJ Open ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. e021401 ◽  
Author(s):  
Abdullah Al-Taiar ◽  
Abdur Rahman ◽  
Reem Al-Sabah ◽  
Lemia Shaban ◽  
Anwar Al-Harbi
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Parental Education ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Gulf Region ◽  
Cross Sectional ◽  
Factors Associated ◽  
Vitamin D Supplement

ObjectivesIn Kuwait, as in many Arab states in the Gulf region, there are limited data on the prevalence of vitamin D deficiency among healthy adolescents. This study aimed to estimate the prevalence of vitamin D deficiency in a nationally representative sample of adolescents and investigate factors associated with vitamin D status.MethodsA cross-sectional study was conducted on 1416 adolescents aged 11–16 years, who were randomly selected from middle schools in all governorates of Kuwait. Data were collected from parents through self-administered questionnaire and from adolescents through face-to-face interview. Vitamin D was measured using liquid chromatography-tandem mass spectrometry. Logistic regression was used to investigate the independent factors associated with vitamin D status.ResultsThe prevalence of vitamin D deficiency was 81.21% (95% CI 71.61% to 90.81%), while severe deficiency was 39.48%. Only 3.60% of adolescents were vitamin D-sufficient. The prevalence of vitamin D deficiency was significantly higher among girls compared with boys (91.69% vs 70.32%; p<0.001). There was a significant inverse correlation between vitamin D and parathyroid hormone (Spearman correlation=−0.35; p<0.001). In the final model, gender, age, governorate, parental education, body mass index, vitamin D supplement and the number of times adolescents walk to schools per week were all significantly related to vitamin D deficiency.ConclusionHigh prevalence of vitamin D deficiency was noted among adolescents in Kuwait despite the abundant sunshine, which may reflect strong sun avoidance behaviour. Adequate outdoor daytime activities should be encouraged especially for girls. We call for locally tailored guidelines for vitamin D supplement in which girls should have a higher dose compared with boys.

scholarly journals Hubungan Kadar Profil Lipid dengan Kejadian Hipertensi pada Masyarakat Etnik Minangkabau di Kota Padang Tahun 2012

2014 ◽  
Vol 3 (2) ◽  
Author(s):  
Rahmat Feryadi ◽  
Delmi Sulastri ◽  
Husnil Kadri
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Cross Sectional Study ◽  
Common Disease ◽  
Ethnic Communities ◽  
Sectional Study ◽  
Significant Relation ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test

AbstrakHipertensi merupakan masalah kesehatan yang banyak dijumpai pada masyarakat dan berkorelasi dengan penyakit lainnya. Banyak faktor penyebab terjadinya hipertensi, salah satunya adalah gangguan profil lipid. Profil lipid dapat memicu terjadinya hipertensi melalui berbagai mekanisme, baik secara langsung atau tidak langsung. Penelitian ini bertujuan untuk meneliti lebih lanjut tentang hubungan obesitas dengan kejadian hipertensi. Penelitian dilakukan pada masyarakat Etnik Minangkabau di 8 kelurahan di kota Padang. Ini adalah studi komparatif menggunakan desain cross sectional study, dengan jumlah subjek 160 responden. Pengumpulan data responden dilakukan dengan wawancara. Pengukuran tekanan darah dilakukan berdasarkan cara yang direkomendasikan WHO dan penetapan nilainya berdasarkan JNC VII. Profil lipid diukur dilaboratorium dengan acuan penilaian berdasarkan NCEP ATP III. Analisis statistik yang digunakan adalah uji chi square. Hasil penelitian ini menunjukkan bahwa sebagian besar gangguan kadar kolesterol terdapat pada penderita hipertensi dari pada normotensi. Uji statistik chi square menunjukkan hubungan yang bermakna antara kadar kolesterol dan trigliserida dengan kejadian hipertensi (total kolesterol p < 0,05; OR = 2,40, trigliserida p< 0,05; OR = 2,49). Kadar HDL dan LDL tidak menunjukkan hubungan yang bermakna terhadap kejadian hipertensi (p > 0,05). Dari hasil tersebut dapat disimpulkan bahwa sebagian fraksi profil lipid mempengaruhi kejadian hipertensi pada etnik Minangkabau yang berada di kota Padang, yaitu kadar kolesterol total dan trigliserida.Kata kunci: Hipertensi, kolestertol total, HDL, LDL, Trigliserida, etnik Minangkabau.AbstractHypertension is a common disease in the community and have correlation with other diseases. Many factor can leads hypertension, such as disturbance of lipid profile. Lipid profile can lead hypertension through a variety of mechanism, either directly or indirectly. This study aims to investigate the lipid profile relation with the incident of hypertension. The research was conducted at the Minangkabau ethnic communities in 8 district in Padang city. This was s a comparative study using a cross sectional study in 160 respondents. Data was collected by interview to get respondent characteristics. Measurement of blood preasure waist and carried out by the WHO recommended and appointment value based on JNC VII. Profile lipid was measured in laboratory and appointment value based on NCEP ATP III. The statistical analysis used chi square test. The result found that the disturbance of total cholesterol and trigliceride more existed in hypertension than normotension population. Chi square statistical test showed there was relation between total cholesterol and triglycerides with hypertension incident (total cholesterol p < 0,05; OR = 2,40 , triglycerides p < 0,05 ; OR = 2,49 ). HDL and LDL had not significant relation with hypertension incident (p > 0.05). The conclusion of this study is some of profil lipid effected hypertension incident at Minangkabau Ethnic in Padang, especially total cholesterol and triglycerides.Keywords: Hypertension, total cholesterol, HDL, LDL, triglycerides, Minangkabau Ethnic

scholarly journals Evaluation of Vitamin D Status among the Doctors of Bangladesh – A Multi-Center Cross-Sectional Study

2021 ◽  
Vol 32 (1) ◽  
pp. 31-38
Author(s):  
Quazi Tarikul Islam ◽  
Md Alimur Reza ◽  
Md Khalilur Rahman ◽  
AFM Nazmul Islam ◽  
Saiyeedur Rahman ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Health Care Professionals ◽  
Integrated Approach ◽  
Cross Sectional Study ◽  
Vitamin D Supplementation ◽  
Sunlight Exposure ◽  
Activity Level ◽  
Vitamin D Status ◽  
Cross Sectional

Introduction: Vitamin D deficiency has been linked to a whole spectrum of diseases including osteoporosis, cancer, diabetes, and cardiovascular and immune disorders. Though Bangladesh is low latitude country, vitamin D Deficiency is serious and wide spread problem in Bangladesh. Physicians of Bangladesh are more vulnerable to low vitamin D status due to long indoor work hours and lack of sunlight exposure in both government & private institute. So, the aim of this study to evaluate vitamin D status among the physicians working around the Bangladesh. Methods: This was a cross-sectional, multicenter study where we enrolled 1112 doctors from 9 different areas of Bangladesh from May 2018 to June 2019. A Blood sample was collected from all participants to measure Serum 25(OH)D and various patient data such as age, gender, BMI, physical activity level during leisure time, use of vitamins and medications, sunlight exposure time, tea/coffee drinking, smoking, H/O comorbidities etc. was collected. Results: Of the 1112 doctors assessed in the study,794 (71.4%) was male and 318 (28.6%) was female. Mean age of the participants was 45.5±11.1 Years. Vitamin D deficiency and insufficiency was found in 734 (65.8%) and 105 (9.4%) participants respectively. Mean vitamin D level was 18.9 ng/ml (±8.6 ng/ml). Less than 5% of participants of Rajshahi, Rangpur, Dhaka, Bogura and Sylhet had sufficient vitamin D level. Vitamin D deficiency was significantly associated with age, obesity, sunlight exposure, physical inactivity, hypertension and vitamin D supplementation. Conclusion: Vitamin D deficiency is very common among physicians of all over Bangladesh. The high prevalence of vitamin D deficiency in the present study points towards urgent need of an integrated approach to detect vitamin D deficiency among health care professionals and treat appropriately. Bangladesh J Medicine January 2021; 32(1) : 31-38

scholarly journals Vitamin D status and pathway genes in five European autoimmune Addison’s disease cohorts

2021 ◽  
Vol 184 (3) ◽  
pp. 377-385
Author(s):  
Marissa Penna-Martinez ◽  
Gesine Meyer ◽  
Anette Boe Wolff ◽  
Beate Skinningsrud ◽  
Corrado Betterle ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Addison’S Disease ◽  
Cross Sectional Study ◽  
Primary Objective ◽  
Addison's Disease ◽  
Nucleotide Polymorphisms ◽  
Vitamin D Status ◽  
Vitamin D Metabolism ◽  
Cross Sectional

Objective While vitamin D regulates immune cells, little is known about it in autoimmune Addison’s disease (AAD). We investigated the vitamin D status in AAD patients from five European populations to assess its deficiency. In addition, we studied two case-control cohorts for vitamin D metabolism and pathway genes. Design Cross-sectional study. Methods A total of 1028 patients with AAD from Germany (n = 239), Italy (n = 328), Norway (n = 378), UK (n = 44) and Poland (n = 39) and 679 controls from Germany (n = 301) and Norway (n = 378) were studied for 25(OH)D3 (primary objective). Secondary objectives (1,25(OH)2D3 and pathway genes) were examined in case-controls from Germany and Norway correlating 25(OH)D3 and single nucleotide polymorphisms within genes encoding the vitamin D receptor (VDR), 1-α-hydroxylase (CYP27B1), 25-hydroxylase (CYP2R1), 24-hydroxylase (CYP24A1) and vitamin D binding protein (GC/DBP). Results Vitamin D deficiency (25(OH)D3 10–20 ng/mL) was highly prevalent in AAD patients (34–57%), 5–22% were severely deficient (<10 ng/mL), 28–38% insufficient (20–30 ng/mL) and only 7–14% sufficient (>30 ng/mL). Lower 25(OH)D3 and 1,25(OH)2D3 levels were observed both in Norwegian and German AAD (P = 0.03/0.003 and P = 1 × 10-5/< 1 × 10-7, respectively) the former was associated with CYP2R1 (rs1553006) genotype G. Whereas controls achieved sufficient median 25(OH)D3 in summers (21.4 to 21.9 ng/mL), AAD patients remained largely deficient (18.0 to 21.2 ng/mL) and synthesize less 1,25(OH)2D3. Conclusion Vitamin D deficiency and insufficiency are highly prevalent in AAD patients. The vitamin D status of AAD may be influenced by genetic factors and suggests individual vitamin D requirements throughout the year.

scholarly journals Dyslipidemia and Vitamin D Status in Diabetic Patients

2022 ◽  
Vol 05 (01) ◽  
Author(s):  
Mohammed Sassi ◽  
Keyword(s):  
Vitamin D ◽  
Lipid Profile ◽  
Vitamin D Deficiency ◽  
Elevated Serum ◽  
Female Gender ◽  
Serum Levels ◽  
Vitamin D Supplementation ◽  
Diabetic Patients ◽  
Vitamin D Status ◽  
Cross Sectional

Background: Dyslipidemia is one of the most common metabolic syndrome among diabetic patients due to several factors include insulin insufficiency, resistance, and central obesity. Furthermore both vitamin D deficiency and diabetes are most public health worldwide problems. Therefore the aim of the present work to study the dyslipidemia and vitamin D status in diabetes patients and also to study the relation between vitamin D status and lipid profile in diabetic patients. Methods: A Cross sectional study conducted on randomly selected diabetic patients whether have vitamin D deficiency with dyslipidemia, vitamin D deficiency with no dyslipidemia or dyslipidemia with no vitamin D deficiency. A total sample 165 patients enrolled in the study with serum lipid profile, vitamin D and glycemic control measured at beginning and end of the study. The data analysis was done through Chi-square or T test at α< 0.05. Result: The data collected on 165 patients revealed that, patients aged 41-60 years were most common, and female gender was twice as male. This study include both types of diabetes with vitamin D deficiency and dyslipidemia or vitamin D deficiency with no dyslipidemia or dyslipidemia with not vitamin D deficiency as control. Therefore, the result of this work confirmed that vitamin D deficiency significant implicated in elevated serum levels of TG, TC, LDL, VLDL, FPG and HbA1C (P< 0.05). However, vitamin D deficiency has linked to slight increased serum HDL levels. In compared to man, vitamin D deficiency linked significantly to dyslipidemia and abnormal high levels blood glucose and HbA1C par in women. Conclusion: The present study revealed that, vitamin D deficiency associated negatively with serum levels of TC, TG, VLDL, LDL, FPG and HbA1C whereas the deficiency of vitamin D linked to elevated HDL levels. In gender distribution lower vitamin D values associated with elevated serum FPG, HbA1C, lipid profile with exception HDL in women. The data of this study suggested that, diabetic patients with dyslipidemia may improve their lipid profile and glucose hemostasis through vitamin D supplementation

Vitamin D Status in Jiroft City Population, South of Iran, 2015-2019

2021 ◽  
Author(s):  
Mohadeseh Kamali ◽  
Mohammad Shariati ◽  
Mehdi Taheri Sarvtin
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Cardiovascular Health ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Men And Women ◽  
The People ◽  
The Status ◽  
25 Oh Vitamin D

Background and Aims: Vitamin D plays an important role in bone health, cardiovascular health, brain development, immune system regulation, mood regulation, and cancer prevention. This study aimed to evaluate the vitamin D status and the prevalence of vitamin D deficiency in Jiroft city, Kerman Province, south of Iran. Materials and Methods: In this cross-sectional study, 5243 people were selected by random sampling during 2015-2019.  Serum 25 (OH) D level was measured by VIDAS 25-OH vitamin D total testing kits. Levels used for definitions were deficient, D3 < 20 ng/ml; insufficient, D3 20-30 ng/ml; adequate, D3 30-100 ng/ml, and potential toxicity, >100 ng/ml.   Results: The mean of vitamin D was 26.03 ng/ml and 24.19 ng/ml in men and women, respectively (p=0.003). The prevalence of vitamin D deficiency was 41.55% and 51.7% in men and women, respectively. A significant relationship was seen between age and level of vitamin D (p=0.001). Conclusions: The results of our study showed that vitamin D deficiency is common among the general population, especially in women in Jiroft city, Kerman Province, south of Iran. Serious plans are needed to improve the status of vitamin D in the people living in this region.

scholarly journals Relationship between 25(OH)D and Colorectal Cancer Prevalence at Dr. Moewardi Hospital Surakarta-Indonesia: A Cross-Sectional Study

2021 ◽  
Vol 9 (B) ◽  
pp. 1591-1595
Author(s):  
Tegoeh Winandar ◽  
Agus Raharjo ◽  
Hari Wujoso ◽  
B. Rina A. Sidharta ◽  
Budhi Ida Bagus
Keyword(s):  
Colorectal Cancer ◽  
Vitamin D ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Colorectal Malignancy ◽  
Diagnostic Measures ◽  
Chi Square Test ◽  
Cross Sectional Design ◽  
Differentiation And Proliferation

Background: Colorectal cancer is a malignancy of the colon and / or rectum. Vitamin D has a role as an inhibitor of tumor progression, namely through the process of influencing cellular differentiation and proliferation. (VDR) Vitamin D Receptor affects cell differentiation by upregulating brush boundary enzymes and improving morphological microvilli. This study seeks to determine the relationship between 25(OH)D levels and colorectal cancer in dr. Moewardi Hospital, Surakarta, Indonesia. Methods: A cross-sectional design study with quantitative-analytical observation was conducted. All patients had symptoms of colorectal cancer, either undiagnosed or previously diagnosed. 25(OH)D samples were taken from a total of 50 patients at dr. Moewardi Surakarta and subsequent diagnostic measures from the results of histopathology were assessed. The parameters assessed were 25(OH)D level and a diagnosis of colorectal malignancy. Statistical analysis of 25(OH)D levels and colorectal diagnosis using the Chi Square test. Results: The prevalence of colorectal cancer is higher in respondents with 25(OH)D deficiency and insufficiency compared to respondents with normal 25(OH)D concentrations who tend to have non-colorectal cancer. Based on the Chi-Square test result, the significance value was 0.004, marking a statistically significant association. Conclusion: This study shows a significant relationship between deficiency and insufficiency of 25(OH)D concentrations with the occurrence of colorectal malignancy

scholarly journals Maternal Awareness of Vitamin D Deficiency in Infants and up to the Age of 6 Years: A Cross Sectional Study in Jordan

2021 ◽  
Author(s):  
Safa'a Al-Qudah ◽  
Leyla Abuhussein ◽  
Samar Al Sbaihi
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Health Problem ◽  
Sun Exposure ◽  
Cross Sectional Study ◽  
Time Of Day ◽  
Online Questionnaire ◽  
Chi Square ◽  
Cross Sectional

Background: Vitamin D Deficiency in children is a worldwide health problem. Yet, there is little known about awareness of parents regarding this issue in Jordan. The recent study aimed to assess the mothers’ knowledge and practices toward vitamin D deficiency in infants and up to age of 6 years. Methods: an online questionnaire was distributed as Google Form on mothers of children between 0-6 yeas, assessing their knowledge about vitamin D, its deficiency, and their practices toward vitamin D deficiency for their children, Descriptive statistics and Chi-Square test were performed. Results: Most of mothers (64.8%) were aged between 30-40 years, and had education level of Bachelor’s degree (63.3%). Sunlight was considered the main source of vitamin D (89.1%), while fish and eggs were the main dietary sources (63.5%, 65.5%, respectively). Vitamin D was considered important for bone and teeth health (93.9%). The majority of participants reported lack of sun exposure and decreased vitamin D rich foods as risk factors and rickets as complication of vitamin D deficiency (98.5%, 96.4%, 89.3%, respectively). Most of mothers (65.1%) indicated the time before 10 AM as the best time of day to expose baby/child to the sun. The majority of participants (82.2%) believe that vitamin D deficiency is a common health problem in children in our country, and 86.4% think they need more information on vitamin D deficiency in children. Age, nationality, nature of housing, and age group of children had an impact on knowledge’s level of participants. Conclusion: Most of participants were aware of vitamin D sources, benefits, risk factors and complications of deficiency, although there was inadequate knowledge among respondents was found in certain domains of vitamin D. More education is required for mothers about vitamin D and its deficiency.

scholarly journals Vitamin D status in Chinese pregnant women and their newborns in Beijing and their relationships to birth size

2012 ◽  
Vol 16 (4) ◽  
pp. 687-692 ◽  
Author(s):  
Shu Jun Song ◽  
Shaoyan Si ◽  
Junli Liu ◽  
Xingming Chen ◽  
Ling Zhou ◽  
...  
Keyword(s):  
Vitamin D ◽  
Birth Weight ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Cross Sectional Study ◽  
Birth Size ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Severe Vitamin ◽  
Beijing China

AbstractObjectiveTo evaluate the prevalence of vitamin D deficiency in pregnant women and their newborns in Beijing, China and the influence of vitamin D deficiency on birth size.DesignA cross-sectional study.SettingData were collected from pregnant women who delivered during April to May 2010 at 306 Hospital of PLA in Beijing, China.SubjectsParticipants in the study were seventy healthy nulliparous pregnant women with singleton pregnancies who delivered healthy babies at full term and their newborns.ResultsSevere vitamin D deficiency (25-hydroxyvitamin D (25(OH)D) < 25 nmol/l) was detected in 54·5 % of mothers and 46·6 % of newborns. Neither mothers nor newborns had serum 25(OH)D concentrations that reached the normal level (>75 nmol/l). The concentration of 25(OH)D in mothers was positively correlated with that in cord blood (r = 0·89, P < 0·001). Newborns of mothers with severe vitamin D deficiency had lower birth length and birth weight. The head circumference and birth weight were lower in vitamin D-deficient newborns.ConclusionsThe study indicates that pregnant women and neonates residing in Beijing are at high risk of vitamin D deficiency. Neonatal 25(OH)D concentrations are dependently related to maternal 25(OH)D levels. Maternal and neonatal vitamin D status influences newborn size.

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