scholarly journals The Role of Chest Computed Tomography in Asymptomatic Patients of Positive Coronavirus Disease 2019: A Case and Literature Review

2020 ◽  
Vol 10 ◽  
pp. 35 ◽  
Author(s):  
Jeton Shatri ◽  
Lirim Tafilaj ◽  
Agon Turkaj ◽  
Kreshnike Dedushi ◽  
Metë Shatri ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Early Detection ◽  
Severe Acute Respiratory Syndrome ◽  
Literature Review ◽  
Primary Source ◽  
Travel History ◽  
Chest Computed Tomography ◽  
Source Of Infection ◽  
Asymptomatic Patients

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. At present, patients are the primary source of infection. A randomly diagnosed confirmed case of COVID-19 highlights the importance of computerized tomography of thorax in diagnosing asymptomatic patients. In the early phase of COVID-19, routine screenings miss patients who are virus carriers, and tracking travel history is of paramount importance to early detection and isolation of SARS-CoV-2 cases.

scholarly journals The role of chest computed tomography in the management of COVID-19: A review of results and recommendations

2020 ◽  
Vol 245 (13) ◽  
pp. 1096-1103 ◽  
Author(s):  
Molly D Wong ◽  
Theresa Thai ◽  
Yuhua Li ◽  
Hong Liu
Keyword(s):  
Computed Tomography ◽  
Early Detection ◽  
Technology Development ◽  
Early Stage ◽  
Chest Ct ◽  
High Rate ◽  
Chest Computed Tomography ◽  
Severity Of The Disease ◽  
The Impact

The rapid and dramatic increase in confirmed cases of COVID-19 has led to a global pandemic. Early detection and containment are currently the most effective methods for controlling the outbreak. A positive diagnosis is determined by laboratory real-time reverse transcriptase polymerase chain reaction (rRT-PCR) testing, but the use of chest computed tomography (CT) has also been indicated as an important tool for detection and management of the disease. Numerous studies reviewed in this paper largely concur in their findings that the early hallmarks of COVID-19 infection are ground-glass opacities (GGOs), often with a bilateral and peripheral lung distribution. In addition, most studies demonstrated similar CT findings related to the progression of the disease, starting with GGOs in early disease, followed by the development of crazy paving in middle stages and finally increasing consolidation in the later stages of the disease. Studies have reported a low rate of misdiagnosis by chest CT, as well as a high rate of misdiagnosis by the rRT-PCR tests. Specifically, chest CT provides more accurate results in the early stages of COVID-19, when it is critical to begin treatment as well as isolate the patient to avoid the spread of the virus. While rRT-PCR will probably remain the definitive final test for COVID-19, until it is more readily available and can consistently provide higher sensitivity, the use of chest CT for early stage detection has proven valuable in avoiding misdiagnosis as well as monitoring the progression of the disease. With the understanding of the role of chest CT, researchers are beginning to apply deep learning and other algorithms to differentiate between COVID-19 and non-COVID-19 CT scans, determine the severity of the disease to guide the course of treatment, and investigate numerous additional COVID-19 applications. Impact statement The impact of the COVID-19 pandemic has been worldwide, and clinicians and researchers around the world have been working to develop effective and efficient methods for early detection as well as monitoring of the disease progression. This minireview compiles the various agency and expert recommendations, along with results from studies published in numerous countries, in an effort to facilitate the research in imaging technology development to benefit the detection and monitoring of COVID-19. To the best of our knowledge, this is the first review paper on the topic, and it provides a brief, yet comprehensive analysis.

scholarly journals Clinical and Dynamic Computed Tomography Features of 24 Patients With Coronavirus Disease 2019

2020 ◽  
pp. 084653712091883 ◽  
Author(s):  
Bingkun Jie ◽  
Xiaojin Liu ◽  
Huaqian Suo ◽  
Guoqing Qiao ◽  
Qingshui Zheng ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Clinical Characteristics ◽  
Close Contact ◽  
Dynamic Computed Tomography ◽  
Chest Tightness ◽  
Wuhan City ◽  
Travel History ◽  
Chest Computed Tomography ◽  
Regional Center ◽  
Interlobular Septal Thickening

Purpose: To explore the clinical and dynamic computed tomography features of coronavirus disease 2019. Methods: We enrolled 24 patients with coronavirus disease 2019 treated at a regional center in Dezhou, China, from January 22 to February 5, 2020, and analyzed data retrospectively. Results: Nineteen cases had close contact with people with coronavirus disease 2019, and five patients denied a travel history in Wuhan City or contact with patients having coronavirus disease 2019. Symptoms were fever, cough, chest tightness, dyspnea, fatigue, and muscle pain. Chest computed tomography showed multiple ground-glass opacities distributed along peribronchial bundles and subpleural areas, often accompanied by bronchiectasis, vascular thickening, and interlobular septal thickening after coronavirus disease 2019 progression. Conclusions: Coronavirus disease 2019 has certain clinical characteristics and typical computed tomography features.

scholarly journals The utility of chest computed tomography (CT) and RT-PCR screening of asymptomatic patients for SARS-CoV-2 prior to semiurgent or urgent hospital procedures

2020 ◽  
Vol 41 (12) ◽  
pp. 1375-1377 ◽  
Author(s):  
Aditya S. Shah ◽  
Lara A. Walkoff ◽  
Ronald S. Kuzo ◽  
Matthew R. Callstrom ◽  
Michael J. Brown ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Ct Scan ◽  
Tertiary Care ◽  
Case Series ◽  
Chest Ct ◽  
Study Cohort ◽  
Rt Pcr ◽  
Chest Computed Tomography ◽  
Tertiary Care Medical Center ◽  
Asymptomatic Patients

AbstractObjective:Presently, evidence guiding clinicians on the optimal approach to safely screen patients for coronavirus disease 2019 (COVID-19) to a nonemergent hospital procedure is scarce. In this report, we describe our experience in screening for SARS-CoV-2 prior to semiurgent and urgent hospital procedures.Design:Retrospective case series.Setting:A single tertiary-care medical center.Participants:Our study cohort included patients ≥18 years of age who had semiurgent or urgent hospital procedures or surgeries.Methods:Overall, 625 patients were screened for SARS-CoV-2 using a combination of phone questionnaire (7 days prior to the anticipated procedure), RT-PCR and chest computed tomography (CT) between March 1, 2020, and April 30, 2020.Results:Of the 625 patients, 520 scans (83.2%) were interpreted as normal; 1 (0.16%) had typical features of COVID-19; 18 scans (2.88%) had indeterminate features of COVID-19; and 86 (13.76%) had atypical features of COVID-19. In total, 640 RT-PCRs were performed, with 1 positive result (0.15%) in a patient with a CT scan that yielded an atypical finding. Of the 18 patients with chest CTs categorized as indeterminate, 5 underwent repeat negative RT-PCR nasopharyngeal swab 1 week after their initial swab. Also, 1 patient with a chest CT categorized as typical had a follow-up repeat negative RT-PCR, indicating that the chest CT was likely a false positive. After surgery, none of the patients developed signs or symptoms suspicious of COVID-19 that would indicate the need for a repeated RT-PCR or CT scan.Conclusion:In our experience, chest CT scanning did not prove provide valuable information in detecting asymptomatic cases of SARS-CoV-2 (COVID-19) in our low-prevalence population.

scholarly journals Effects of Severe Acute Respiratory Syndrome Coronavirus 2 Infection on Pregnant Women and Their Infants

2020 ◽  
Vol 144 (10) ◽  
pp. 1217-1222 ◽  
Author(s):  
Hui Yang ◽  
Bin Hu ◽  
Sudong Zhan ◽  
Li-ye Yang ◽  
Guoping Xiong
Keyword(s):  
Computed Tomography ◽  
Severe Acute Respiratory Syndrome ◽  
Pregnant Women ◽  
Perinatal Death ◽  
Severe Pneumonia ◽  
Neonatal Morbidity ◽  
Late Pregnancy ◽  
Chest Computed Tomography ◽  
Polymerase Chain ◽  
Novel Coronavirus

Context.— The pandemic of a novel coronavirus, termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has created an unprecedented global health burden. Objective.— To investigate the effect of the SARS-CoV-2 infection on maternal, fetal, and neonatal morbidity and other poor obstetrical outcomes. Design.— All suspected cases of pregnant women with coronavirus disease 2019 (COVID-19) admitted into one center in Wuhan from January 20 to March 19, 2020, were included. Detailed clinical data of those pregnancies with COVID-19 were retrospectively collected and analyzed. Results.— Twenty-seven pregnant women (4 early pregnancies included) with laboratory or clinically confirmed SARS-CoV-2 infection and 24 neonates born to the 23 women in late pregnancy were analyzed. On admission, 46.2% (13 of 27) of the patients had symptoms, including fever (11 of 27), cough (9 of 27), and vomiting (1 of 27). Decreased total lymphocytes count was observed in 81.5% (22 of 27) of patients. Twenty-six patients showed typical viral pneumonia by chest computed tomography scan, whereas 1 patient confirmed with COVID-19 infection showed no abnormality on chest computed tomography. One mother developed severe pneumonia 3 days after her delivery. No maternal or perinatal death occurred. Moreover, 1 early preterm newborn born to a mother with the complication of premature rupture of fetal membranes, highly suspected to have SARS-CoV-2 infection, was SARS-CoV-2 negative after repeated real-time reverse transcriptase polymerase chain reaction testing. Statistical differences were observed between the groups of women in early and late pregnancy with COVID-19 in the occurrence of lymphopenia and thrombocytopenia. Conclusions.— No major complications were reported among the studied cohort, though 1 serious case and 1 perinatal infection were observed. Much effort should be made to reduce the pathogenic effect of COVID-19 infection in pregnancies.

scholarly journals Role of Chest Computed Tomography in Head and Neck Cancer

2008 ◽  
Vol 134 (10) ◽  
pp. 1050 ◽  
Author(s):  
Yen-Bin Hsu ◽  
Pen-Yuan Chu ◽  
Juhn-Cherng Liu ◽  
Ming-Chin Lan ◽  
Shyue-Yih Chang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Chest Computed Tomography

scholarly journals The role of a chest computed tomography severity score in coronavirus disease 2019 pneumonia

Medicine ◽  
2020 ◽  
Vol 99 (42) ◽  
pp. e22433
Author(s):  
Fausto Salaffi ◽  
Marina Carotti ◽  
Marika Tardella ◽  
Alessandra Borgheresi ◽  
Andrea Agostini ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Severity Score ◽  
Chest Computed Tomography

scholarly journals Chest Computed Tomography Findings in Asymptomatic Patients with COVID-19

Respiration ◽  
2020 ◽  
Vol 99 (9) ◽  
pp. 748-754 ◽  
Author(s):  
Min Cheol Chang ◽  
Wonho Lee ◽  
Jian Hur ◽  
Donghwi Park
Keyword(s):  
Computed Tomography ◽  
South Korea ◽  
Respiratory System ◽  
Ground Glass Opacity ◽  
Chest Ct ◽  
Effective Management ◽  
Radiographic Findings ◽  
Chest Computed Tomography ◽  
Asymptomatic Patients ◽  
The Right

<b><i>Background:</i></b> Little is known about the damage to the respiratory system in asymptomatic patients with coronavirus disease (COVID-19). <b><i>Objective:</i></b> Herein, we evaluate the findings of chest computed tomography (CT) and radiography in patients with COVID-19 who were asymptomatic. <b><i>Methods:</i></b> We retrospectively investigated patients with a confirmed diagnosis of COVID-19 but who did not show any symptoms. Among the 139 patients with COVID-19 who were hospitalized in Yeungnam University Hopistal in Daegu, South Korea, 10 (7.2%) were asymptomatic. Their chest CT and radiographic findings were analyzed. <b><i>Results:</i></b> In the results, all patients (100%) had ground-glass opacity (GGO) on chest CT. Further, the GGO lesions were predominantly distributed peripherally and posteriorly in all patients. In 9 (90%) patients, the GGO lesions were combined with reticular opacity. Air bronchogram due to bronchiolectasis surrounded by GGO was observed in 8 patients (80%). Additionally, the lung lesions were dominant on the right side in all patients. <b><i>Conclusions:</i></b> In conclusion, considering our results that the lung is affected in asymptomatic patients, it will be necessary to extend the indications of COVID-19 testing for effective management of COVID-19 during the pandemic.

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