scholarly journals Mortality Data in Mechanically Ventilated COVID-19 patients admitted to ICU: A Retrospective Study in Brooklyn

2021 ◽  
Vol 03 (04) ◽  
Author(s):  
Ravi Karan Patti ◽  
Claudia De Araujo Duarte ◽  
Rajat Thawani ◽  
Nishil Dalsania ◽  
Bruno Augusto de Brito Gomes ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Mortality Data ◽  
Mechanically Ventilated

Association of opioid exposure during intensive care unit stays with post-discharge opioid use: A retrospective study and literature review

2021 ◽  
Vol 17 (6) ◽  
pp. 511-516
Author(s):  
Yoonsun Mo, MS, PharmD, BCPS, BCCCP ◽  
John Zeibeq, MD ◽  
Nabil Mesiha, MD ◽  
Abou Bakar, PharmD ◽  
Maram Sarsour, PharmD ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Retrospective Study ◽  
Hospital Discharge ◽  
Invasive Mechanical Ventilation ◽  
High Dose ◽  
Opioid Use ◽  
Electronic Health Record Data ◽  
Icu Patients ◽  
Mechanically Ventilated

Objective: To evaluate whether pain management strategies within intensive care unit (ICU) settings contribute to chronic opioid use upon hospital discharge in opioid-naive patients requiring invasive mechanical ventilation. Design: A retrospective, observational study.Setting: An 18-bed mixed ICU at a community teaching hospital located in Brooklyn, New York.Participants: This study included mechanically ventilated patients requiring continuous opioid infusion from April 25, 2017 to May 16, 2019. Patients were excluded if they received chronic opioid therapy at home or expired during this hospital admission. Eligible patients were identified using an electronic health record data query.Main outcome measure(s): The proportion of ICU patients who continued to require opioids upon ICU and hospital discharge. Results: A total of 196 ICU patients were included in this study. Of these, 22 patients were transferred to a regular floor while receiving a fentanyl transdermal patch. However, the fentanyl patch treatment was continued only for three patients (2 percent) at hospital discharge.Conclusions: This retrospective study suggested that high-dose use of opioids in mechanically ventilated, opioid-naive ICU patients was not associated with continued opioid use upon hospital discharge.

scholarly journals Variables predicting weaning outcome in prolonged mechanically ventilated tracheotomized patients: a retrospective study

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Alessandro Ghiani ◽  
Joanna Paderewska ◽  
Alexandros Sainis ◽  
Alexander Crispin ◽  
Swenja Walcher ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Mechanically Ventilated ◽  
Weaning Outcome

scholarly journals Mortality Data in Mechanically Ventilated COVID-19 patients admitted to ICU: A Retrospective Study in Brooklyn

2020 ◽  
Author(s):  
Ravi Karan Patti ◽  
Claudia De Araujo Duarte ◽  
Nishil Dalsania ◽  
Rajat Thawani ◽  
Ankur Sinha ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Ventilatory Support ◽  
Supportive Therapy ◽  
Secondary Outcome ◽  
Mortality Data ◽  
Mechanical Ventilatory Support ◽  
Mechanically Ventilated ◽  
Care Community ◽  
Early Intubation ◽  
Vasopressor Use

Abstract Background: High mortality rates are predominant even in COVID-19 patients requiring minimal supportive therapy, with a short-coming of data on COVID-19 patients requiring mechanical ventilation.Objectives/Design: We performed a single-center, retrospective, cohort study at a tertiary care, community-based teaching hospital with patient who required invasive mechanical ventilatory support and were COVID-19 positive. All patients were treated according to the ARDSnet protocol. The primary outcome was overall mortality, and secondary outcome was successful extubation.Results: A total of 72 COVID-19 positive intubated patients were included. Twenty-six (66.6%) patients died within the first 15 days of hospital admission; thirty-eight (52.7%) died within 28 days, and thirty-nine (54.2%) died within 29 days. A total of 22 patients (30.5%) were successfully extubated. 15 patients (20.8%) who required reintubation or could not be extubated further underwent tracheostomy.Conclusions: Mortality of critically ill COVID-19 patients requiring mechanical ventilatory support is high, our observed mortality rate (54.2%) was significantly lower than currently published reports. We believe our rate to be a consequence of early intubation in conjunction with adherence to ARDSnet protocol. We also observed patients with hyperlipidemia, higher CRP, renal failure, or those requiring vasopressor use had worse outcomes.

Peritoneal Infections in Children Undergoing Acute Peritoneal Dialysis at a Tertiary/Quaternary Central Hospital in Kwazulu-Natal, South Africa

2018 ◽  
Vol 38 (6) ◽  
pp. 413-418 ◽  
Author(s):  
Mulalo Nepfumbada ◽  
Elaene Naicker ◽  
Rajendra Bhimma
Keyword(s):  
South Africa ◽  
Peritoneal Dialysis ◽  
Retrospective Study ◽  
Referral Hospital ◽  
Mortality Data ◽  
Central Hospital ◽  
Poststreptococcal Glomerulonephritis ◽  
Gram Negative ◽  
Kwazulu Natal ◽  
Gram Negative Organisms

Background In a resource-limited setting, acute peritoneal dialysis (APD) is the modality of choice as a form of renal replacement therapy in children with acute kidney injury (AKI). However, there is a high risk of peritonitis that causes significant morbidity and mortality. Data on PD and peritonitis in developing countries are scarce. The purpose of this retrospective study was to determine the prevalence of APD-related peritonitis at a central referral hospital in KwaZulu-Natal, South Africa. Methods A retrospective study from January 2010 until December 2014 was done at Inkosi Albert Luthuli Central Hospital (IALCH). All children under the age of 13 years with AKI requiring APD were included in the study. Results Forty children were included in the study. Age ranged from 0.2 years to 12.25 years; 25 (62.5%) were male and 15 (37.5%) female. Twenty-seven (67.5%) were admitted to the intensive care unit (ICU) and 13 (32.5%) to the pediatric high care ward. Septicemia with multi-organ dysfunction was the was the main cause of AKI requiring APD in 18 (45%) children followed by poststreptococcal glomerulonephritis in 8 (20%). Acute PD was complicated by culture-proven peritonitis in 19 (47.5%) children of whom 16 (84.2%) had a single organism cultured while in 3, (15.7%) there was a mixed culture. The total number of organisms cultured was 24: 8 (33.3%) were gram-positive organisms, 12 (50%) gram-negative organisms, and 4 (16.67%) fungal. The Paediatric Index of Mortality (PIM) 2 Score risk of mortality was 99.4% for patients admitted to ICU. Mortality rate was 65%, and 14 (53%) of the children who demised had peritonitis. Conclusion This study showed an inordinately high complication rate of peritonitis, mostly secondary to gram-negative organisms, of children undergoing APD in a central referral hospital. The use of surgically placed, tunneled catheters, meticulous attention to aseptic techniques and judicious use of antimicrobials is highly recommended in reducing the incidence of peritonitis in children undergoing APD.

scholarly journals A RETROSPECTIVE STUDY OF MECHANICALLY-VENTILATED PATIENTS WITH SNAKEBITE ADMITTED IN ICU

2017 ◽  
Vol 4 (33) ◽  
pp. 1975-1978
Author(s):  
Riyaz Ahamed ◽  
Ravishankar R.B ◽  
Syeda Shaista Naz ◽  
Narasimha Gnani B.C
Keyword(s):  
Retrospective Study ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Ventilated Patients

scholarly journals Retrospective study on 48-h fluid balance and outcome in mechanically ventilated critically ill children

2020 ◽  
Vol 7 (4) ◽  
pp. 174
Author(s):  
Ramachandran Rameshkumar ◽  
Namita Ravikumar ◽  
Ponnarmeni Satheesh ◽  
Subramanian Mahadevan
Keyword(s):  
Retrospective Study ◽  
Critically Ill ◽  
Fluid Balance ◽  
Critically Ill Children ◽  
Mechanically Ventilated

Trends in the epidemiology of invasiveHaemophilus influenzaedisease in Queensland, Australia from 2000 to 2013: what is the impact of an increase in invasive non-typableH. influenzae(NTHi)?

2015 ◽  
Vol 143 (14) ◽  
pp. 2993-3000 ◽  
Author(s):  
J. WAN SAI CHEONG ◽  
H. SMITH ◽  
C. HENEY ◽  
J. ROBSON ◽  
S. SCHLEBUSCH ◽  
...  
Keyword(s):  
Public Health ◽  
Retrospective Study ◽  
Clinical Impact ◽  
Mortality Data ◽  
Infection Site ◽  
Type B ◽  
Indigenous Status ◽  
Epidemiological Trends ◽  
The Impact ◽  
Multicentre Retrospective Study

SUMMARYFollowing the introduction of vaccination againstHaemophilus influenzaetype b (Hib), cases of invasive encapsulated Hib disease have decreased markedly. This study aimed to examine subsequent epidemiological trends in invasiveH. influenzaedisease in Queensland, Australia and in particular, assess the clinical impact and public health implications of invasive non-typableH. influenzae(NTHi) strains. A multicentre retrospective study was conducted from July 2000 to June 2013. Databases of major laboratories in Queensland including Queensland Forensic and Scientific Services (jurisdictional referral laboratory for isolate typing) were examined to identify cases. Demographic, infection site, Indigenous status, serotype, and mortality data were collected. In total, 737 invasive isolates were identified, of which 586 (79·5%) were serotyped. Hib, NTHi and encapsulated non-b strains, respectively, constituted 12·1%, 69·1% and 18·8% of isolates. The predominant encapsulated non-b strains were f (45·5%) and a (27·3%) serotypes. Of isolates causing meningitis, 48·9% were NTHi, 14·9% Hib, 14·9% Hie, 10·6% Hif, 6·4% Hia and 4·3% were untyped. During the study period, there was an increase in the incidence of invasive NTHi disease (P= 0·007) with seasonal peaks in winter and spring (P< 0·001). The incidence of Hib disease (P= 0·295) and of encapsulated non-b disease (P= 0·122) did not change significantly. Highest overall incidence was in infants, Indigenous, and elderly patients. Australian Indigenous patients were more likely to have Hia (P> 0·001) and Hib (P= 0·039) than non-Indigenous patients. In Queensland, invasiveH. influenzaedisease is now predominantly encountered in adults and most commonly caused by NTHi strains with demonstrated pathogenicity extending to otherwise young or immunocompetent individuals. Routine public health notification of these strains is recommended and recent available immunization options should be considered.

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