The Cervix-Ripening Effect of the Prostaglandin E Analogue Sulprostone, Before Vacuum Aspiration in First Trimester Pregnancy

1983 ◽  
Vol 62 (s113) ◽  
pp. 141-144 ◽  
Author(s):  
H. Fehrmann ◽  
B. Praetorius
1989 ◽  
Vol 27 (26) ◽  
pp. 103-103

During labour endogenous prostaglandins are involved in the process of softening the cervix. Gemeprost, an analogue of prostaglandin E1, is used as a vaginal pessary (Cervagem - May & Baker) to soften and dilate the cervix before vacuum aspiration of first-trimester pregnancy.1 It can now also be used for medical termination of pregnancy in the mid-trimester.


1987 ◽  
Vol 25 (13) ◽  
pp. 51-52

Gemeprost (Cervagem - M & B) is a vaginal pessary licensed for use to promote softening and dilatation of the cervix before operative abortion of first trimester pregnancy. It contains 1mg of a stable methylated analogue of prostaglandin E1. A single pessary is inserted three hours before surgery.


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