Serum CA 125 Levels in Patients with a Provisional Diagnosis of Pelvic Inflammatory Disease: Clinical and Theoretical Implications

1989 ◽  
Vol 68 (7) ◽  
pp. 637-641 ◽  
Author(s):  
Jitze M. Duk ◽  
Frank M. Kauer ◽  
Gert Jan Fleuren ◽  
Henk W.A. de Bruijn
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Ca 125 ◽  
Provisional Diagnosis

CA 125 in Benign Gynecological Conditions

1998 ◽  
Vol 13 (4) ◽  
pp. 231-237 ◽  
Author(s):  
H. Meden ◽  
A. Fattahi-Meibodi
Keyword(s):  
Tumor Marker ◽  
Ectopic Pregnancy ◽  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Cirrhosis Of The Liver ◽  
Ca 125 ◽  
Ovarian Cysts ◽  
Gynecological Tumors ◽  
Ovarian Abscess

The tumor marker CA 125 was initially thought to be specific for ovarian malignancies. Subsequently it was found to be raised in a variety of benign conditions, including pregnancy, pelvic inflammatory disease, tuberculosis and cirrhosis of the liver. With respect to gynecological tumors, CA 125 may be elevated in benign ovarian cysts, tubo-ovarian abscess, endometriosis, hyperstimulation syndrome, ectopic pregnancy and fibroids. These results demonstrate that CA 125 is a marker of non-specific peritoneal conditions.

scholarly journals Very High CA125 due to Non-neoplastic Lesion of Ovary

2014 ◽  
Vol 7 (2) ◽  
pp. 52-54
Author(s):  
KDB Bista
Keyword(s):  
Tumor Marker ◽  
Pelvic Inflammatory Disease ◽  
Young Woman ◽  
Inflammatory Disease ◽  
Abdominal Tuberculosis ◽  
Ca 125 ◽  
Ovarian Malignancy ◽  
Obstetrics And Gynaecology ◽  
Neoplastic Lesion ◽  
Very High

High CA-125 levels have been strongly associated with ovarian malignancy. But due to nonspecific nature of this tumor marker it has been found to be raised to high levels above 1000u/Ml even in some non neoplastic conditions which have to be kept in mind. A young woman was found to have very high Ca125 levels of 3500u/Ml after rupture of endometrioma. Endometrioma, pelvic inflammatory disease, abdominal tuberculosis are some of the nonneoplastic conditions associated with very high levels of Ca125. DOI: http://www.dx.doi.org/10.3126/njog.v7i2.11146   Nepal Journal of Obstetrics and Gynaecology / Vol 7 / No. 2 / Issue 14 / July-Dec, 2012 / 52-54

Serum CA-125 in the diagnosis of acute pelvic inflammatory disease

1994 ◽  
Vol 44 (1) ◽  
pp. 53-57 ◽  
Author(s):  
J. Mozas ◽  
J.A. Castilla ◽  
P. Jimena ◽  
T. Gil ◽  
M. Acebal ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Ca 125 ◽  
Acute Pelvic Inflammatory Disease

scholarly journals Pelvic Inflammatory Disease: Possible Catches and Correct Management in Young Women

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Chiara Di Tucci ◽  
Daniele Di Mascio ◽  
Michele Carlo Schiavi ◽  
Giorgia Perniola ◽  
Ludovico Muzii ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Young Women ◽  
Inflammatory Disease ◽  
Transvaginal Ultrasound ◽  
Correct Diagnosis ◽  
Pelvic Mass ◽  
Treatment Decision ◽  
Ca 125 ◽  
Fertility Sparing ◽  
The Right

The incidence of adnexal masses increases exponentially with age and the most frequent causes in young women are physiologic cysts and pelvic abscesses with pelvic inflammatory disease (PID). Clinical examination can direct physicians to an appropriate management of adnexal mass, but the role of transvaginal ultrasound is crucial for diagnosis and treatment decision, even if it sometimes can be misleading, especially in young women. Ca 125, blood count, and CRP are useful to clarify suspected etiology of a pelvic mass, but specificity and positive predictive value are low because elevation of laboratory tests may occur in several benign conditions. In our work we present four cases of suspected pelvic masses. Despite guidelines for management of PID, the right timing to switch to surgical therapy is not clear. Therefore, the treatment decision should be based on a careful evaluation of various parameters such as signs symptoms and above all age. Moreover, we believe that, for a correct diagnosis and for the best fertility sparing treatment, it is also extremely important to refer to a gynecological oncology unit with an expert surgeon.

scholarly journals Erroneously Suspected Ovarian Cancer in a 38-Year-Old Woman with Pelvic Inflammatory Disease and Chlamydia

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Romana Brun ◽  
Juliane Hutmacher ◽  
Daniel Fink ◽  
Patrick Imesch
Keyword(s):  
Ovarian Cancer ◽  
Ct Scan ◽  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Transmitted Disease ◽  
Young Patients ◽  
Chlamydia Infection ◽  
Ca 125 ◽  
Abdominal Sonography ◽  
Sexually Transmitted

Chlamydia trachomatis is the most common bacterial cause of sexually transmitted disease and can cause pelvic inflammatory disease (PID), leading to severe outcomes such as ectopic pregnancy, infertility, or pelvic pain. We report a case of a 38-year-old patient with abdominal pain and dyspareunia. Clinical examination revealed diffuse abdominal tenderness. Vaginal and abdominal sonography showed substantial ascites and CA-125 level was elevated. Therefore, the attendant physician performed an abdominal CT scan for further diagnosis. Radiographically diffuse peritoneal enhancement, consistent with peritoneal carcinomatosis, 4-quadrant ascites, and slightly enlarged ovaries with solid and cystic structures were diagnosed, leading to the suspicion of ovarian cancer. In addition, the results of the cervical smear PCR for chlamydia were positive. Due to the positive chlamydia result, the suspicious CT scan, and the young age, we decided to perform a diagnostic laparoscopy as a first step. Intraoperatively, the ovaries were of normal aspect without any cancerous lesions. However, the ascites and the yellow-reddish jelly-like deposits were consistent with acute PID. Thus, chlamydia infection may simulate the presentation of ovarian cancer. Therefore, especially in young patients, we recommend careful scrutiny of every diagnosis of ovarian cancer even if its presentation seems to be typical.

Serum CA 125 in acute pelvic inflammatory disease

1989 ◽  
Vol 96 (5) ◽  
pp. 574-579 ◽  
Author(s):  
J. PAAVONEN ◽  
A. MIETTINEN ◽  
P. K. HEINONEN ◽  
R-K. AARAN ◽  
K. TEISALA ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Ca 125 ◽  
Acute Pelvic Inflammatory Disease
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