In-vivo Proliferative potential of primary human brain tumors; its correlation with histological classification and morphological features: I gliomas

Pathology ◽  
1993 ◽  
Vol 25 (1) ◽  
pp. 4-9 ◽  
Author(s):  
Amit K. Dinda ◽  
Kusum Kharbanda ◽  
Chitra Sarkar ◽  
Subimal Roy ◽  
Meera Mathur ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Morphological Features ◽  
Proliferative Potential ◽  
Histological Classification ◽  
Human Brain Tumors

Cell kinetics studies of human brain tumors by in vitro labeling using anti-BUdR monoclonal antibody

1988 ◽  
Vol 69 (3) ◽  
pp. 371-374 ◽  
Author(s):  
Takafumi Nishizaki ◽  
Tetsuji Orita ◽  
Masahide Saiki ◽  
Yasuhiro Furutani ◽  
Hideo Aoki
Keyword(s):  
Monoclonal Antibody ◽  
Brain Tumors ◽  
Human Brain ◽  
Intravenous Infusion ◽  
Reproductive Age ◽  
Proliferative Potential ◽  
Human Brain Tumor ◽  
Human Brain Tumors

✓ Since the development of a specific monoclonal antibody against the thymidine analogue bromodeoxyuridine (BUdR), many investigators have used intravenous infusion of BUdR to estimate the proliferative potential of human brain tumors. However, side effects such as the induction of cell mutation, latent virus promotion, or inhibition of cytodifferentiation cannot be ignored, and thus many workers hesitate to use it in patients, especially those with hepatic disease or of reproductive age. Furthermore, if BUdR remains in the deoxyribonucleic acid of tumor cells after injection, analysis of the effect of chemical and radiation therapy may not be evaluated correctly. In this report, in vitro BUdR labeling with an anti-BUdR antibody is compared with the in vivo methods described by previous authors. This method appears to be useful for determining the S-phase fraction of human brain tumor. It was more rapid, and was simple, safe, and reproducible as compared to the intravenous infusion method.

Expression of Vascular Endothelial Growth Factor in Human Brain Tumors In Vivo

Brain Tumor ◽  
1996 ◽  
pp. 237-245 ◽  
Author(s):  
Kiyonobu Ikezaki ◽  
Ken Samoto ◽  
Takanori Inamura ◽  
Tadahisa Shono ◽  
Masashi Fukui ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Brain Tumors ◽  
Human Brain ◽  
Vascular Endothelial ◽  
Human Brain Tumors ◽  
Endothelial Growth Factor

In vivo CT measurement of blood-brain transfer constant of iopamidol in human brain tumors

1992 ◽  
Vol 14 (2) ◽  
Author(s):  
W.T. Ivan Yeung ◽  
Ting-Yim Lee ◽  
RolandoF. Del Maestro ◽  
Roman Kozak ◽  
Thomas Brown
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Transfer Constant ◽  
Human Brain Tumors ◽  
Blood Brain ◽  
Ct Measurement

scholarly journals Metabolism of [U-13 C]glucose in human brain tumors in vivo

2012 ◽  
Vol 25 (11) ◽  
pp. 1234-1244 ◽  
Author(s):  
Elizabeth A. Maher ◽  
Isaac Marin-Valencia ◽  
Robert M. Bachoo ◽  
Tomoyuki Mashimo ◽  
Jack Raisanen ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Human Brain Tumors

In vivo and in vitro NMR of human brain tumors

1997 ◽  
pp. 439-440
Author(s):  
V. Tugnoli ◽  
M. R. Tosi ◽  
A. Bertoluzza ◽  
G. Barbarella ◽  
R. Ricci
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Human Brain Tumors

Localized, water-suppressed in vivo H MR spectroscopy of human brain tumors: Preliminary results

1993 ◽  
Vol 29 (5) ◽  
pp. 861 ◽  
Author(s):  
Bo Young Choe ◽  
Tae Suk Suh ◽  
Kyu Ho Choi ◽  
Ki Tae Kim ◽  
Kyung Sub Shinn
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Mr Spectroscopy ◽  
Human Brain Tumors ◽  
Preliminary Results

scholarly journals In vivo 1 H MRS detection of cystathionine in human brain tumors

2019 ◽  
Vol 82 (4) ◽  
pp. 1259-1265
Author(s):  
Francesca Branzoli ◽  
Dinesh K. Deelchand ◽  
Marc Sanson ◽  
Stéphane Lehéricy ◽  
Małgorzata Marjańska
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Human Brain Tumors

Oxidative metabolism and glycolysis in benign brain tumors

1987 ◽  
Vol 67 (3) ◽  
pp. 336-340 ◽  
Author(s):  
Terry Lichtor ◽  
George J. Dohrmann
Keyword(s):  
Brain Tumors ◽  
Human Brain ◽  
Oxidative Metabolism ◽  
Glucose Utilization ◽  
Content Type ◽  
Human Brain Tumors ◽  
Elevated Glucose ◽  
Slow Growing

✓ Glucose utilization in vivo and hexokinase activity and mitochondrial oxygen consumption in vitro were measured in a series of human brain tumors. Several relatively slow-growing tumors appeared to have depressed electron-transport activities coupled with a compensatory elevated glucose utilization. These data suggest that a decrease in oxidative metabolism and a corresponding increase in glycolysis are not necessarily correlated with malignancy in certain human brain tumors.

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