Specific Interaction of Postsynaptic Densities With Membrane Rafts Isolated From Synaptic Plasma Membranes

2013 ◽  
Vol 27 (1-2) ◽  
pp. 43-58 ◽  
Author(s):  
Qian Liu ◽  
Wei-Dong Yao ◽  
Tatsuo Suzuki
Keyword(s):  
Plasma Membranes ◽  
Specific Interaction ◽  
Membrane Rafts ◽  
Synaptic Plasma Membranes

Polypeptide antigens of the synaptic plasma membranes of the rat brain

1982 ◽  
Vol 3 (3) ◽  
pp. 181-185 ◽  
Author(s):  
Mahmoud Dewair ◽  
Johannes Wildmann
Keyword(s):  
Rat Brain ◽  
Plasma Membranes ◽  
Synaptic Plasma Membranes

Sodium affinity of brain Na(+)-K(+)-ATPase is dependent on isozyme and environment of the pump

1990 ◽  
Vol 258 (5) ◽  
pp. C803-C811 ◽  
Author(s):  
J. L. Brodsky ◽  
G. Guidotti
Keyword(s):  
Plasma Membranes ◽  
Fibroblast Cell ◽  
Mouse Fibroblast ◽  
Synaptic Plasma Membranes ◽  
Apparent Dissociation Constant ◽  
Low Sodium ◽  
Physiological Relevance ◽  
Mouse Fibroblast Cell Line

The sodium affinities for the two forms of the Na(+)-K(+)-ATPase in brain were characterized. To mimic physiological conditions, synaptosomes, which are pinched off presynaptic nerve termini, were used. Examination of the pump in vitro was performed by preparing synaptic plasma membranes (SPMs). It was first shown that synaptosomes contain the two forms of the Na(+)-K(+)-ATPase, alpha 1 and alpha 2, and that these forms have markedly different affinities for the inhibitory cardiac glycoside ouabain. The apparent dissociation constant (K0.5) of alpha 1 for sodium changed from 12 to 9 mM when going from synaptosomes to membranes. For alpha 2, however, a shift from 36 to 12.5 mM was evident. The conclusion is that in vivo alpha 2 exists as a low sodium affinity species but can be altered to a high-affinity form simply by vesicle disruption. By comparison, the Na(+)-K(+)-ATPase from the mouse fibroblast cell line, 3T3-F442A cells, expressed only the alpha 1-isozyme, as shown by immunoblotting and by measurement of its ouabain and sodium affinities. The physiological relevance of these observations is also presented.

The Role of Phosphoprotein B-50 in Phosphoinositide Metabolism in Brain Synaptic Plasma Membranes

1985 ◽  
pp. 399-414 ◽  
Author(s):  
W. H. Gispen ◽  
C. J. Van Dongen ◽  
P. N. E. De Graan ◽  
A. B. Oestreicher ◽  
H. Zwiers
Keyword(s):  
Plasma Membranes ◽  
Phosphoinositide Metabolism ◽  
Synaptic Plasma Membranes

Small angle X-ray diffraction studies on the topography of cannabinoids in synaptic plasma membranes

1991 ◽  
Vol 40 (3) ◽  
pp. 547-552 ◽  
Author(s):  
Thomas Mavromoustakos ◽  
De-Ping Yang ◽  
Wanda Broderick ◽  
Donna Fournier ◽  
Alexandros Makriyannis
Keyword(s):  
Small Angle ◽  
Plasma Membranes ◽  
X Ray Diffraction ◽  
Synaptic Plasma Membranes ◽  
X Ray

Effects of Maternal Protein Deficiency on Synaptic Plasma Membranes in Offspring

1982 ◽  
Vol 5 (5-6) ◽  
pp. 403-411 ◽  
Author(s):  
Duane M. Smith ◽  
Mary J. Druse
Keyword(s):  
Plasma Membranes ◽  
Protein Deficiency ◽  
Synaptic Plasma Membranes
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